Best TWAS P=7.16e-17 · Best GWAS P=1.45e-21 conditioned to 0.000868
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | TRIB2 | 0.17 | 0.03 | lasso | 7 | 0.04 | 2.9e-03 | -7.3 | -8.3 | 7.2e-17 | 0.86 | 0.04 | 0.91 | TRUE |
| 4 | NTR | Blood | TRIB2 | 0.03 | 0.00 | blup | 477 | 0.01 | 7.2e-04 | 7.5 | -7.7 | 1.0e-14 | 0.48 | 0.08 | 0.32 | TRUE |
| 5 | ROSMAP | Brain Pre-frontal Cortex | TRIB2 | 0.13 | 0.06 | enet | 19 | 0.12 | 1.6e-14 | -5.9 | -6.9 | 4.0e-12 | 0.63 | 0.99 | 0.01 | FALSE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | TRIB2 | 0.04 | 0.01 | blup | 56 | 0.01 | 2.3e-02 | -6.7 | -6.8 | 1.0e-11 | 0.62 | 0.02 | 0.26 | FALSE |
| 6 | YFS | Blood | TRIB2 | 0.04 | 0.01 | enet | 16 | 0.03 | 2.6e-09 | -3.7 | -5.9 | 3.1e-09 | 0.51 | 0.78 | 0.19 | FALSE |
| 2 | GTEx | Lung | TRIB2 | 0.11 | 0.04 | lasso | 6 | 0.05 | 8.9e-05 | 4.9 | -5.3 | 9.9e-08 | 0.59 | 0.46 | 0.14 | FALSE |
| 3 | GTEx | Muscle Skeletal | TRIB2 | 0.08 | 0.03 | lasso | 3 | 0.02 | 2.5e-03 | -6.7 | -5.2 | 2.3e-07 | 0.55 | 0.21 | 0.08 | FALSE |