[Hub]/) : Traits : Blood White Count : ← →

chr1:246,449,849-248,302,707

Best TWAS P=2.73e-36 · Best GWAS P=7.33e-32 conditioned to 0.41

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous ZNF496 0.24 0.12 lasso 7 0.14 1.1e-11 5.6 5.3 9.1e-08 -0.06 1.00 0.00 FALSE
2 GTEx Artery Tibial ZNF496 0.14 0.11 lasso 3 0.12 2.6e-09 5.6 5.5 4.4e-08 -0.05 1.00 0.00 FALSE
3 GTEx Brain Cerebellum ZNF496 0.26 0.13 enet 24 0.12 1.7e-04 -4.6 5.9 3.0e-09 -0.14 0.21 0.11 FALSE
4 GTEx Breast Mammary Tissue ZNF496 0.15 0.16 lasso 4 0.13 4.0e-07 5.6 5.4 5.7e-08 -0.05 0.99 0.00 FALSE
5 GTEx Breast Mammary Tissue (Female) ZNF496 0.19 0.11 lasso 2 0.10 9.0e-04 5.6 5.6 2.1e-08 -0.05 0.08 0.05 FALSE
6 GTEx Cells Transformed fibroblasts ZNF496 0.17 0.12 lasso 3 0.12 6.0e-09 5.6 5.4 6.9e-08 -0.05 1.00 0.00 FALSE
7 GTEx Nerve Tibial ZNF496 0.29 0.24 lasso 5 0.27 5.2e-19 5.6 5.3 8.7e-08 -0.05 1.00 0.00 FALSE
8 GTEx Pancreas ZNF496 0.27 0.20 lasso 6 0.20 9.0e-09 5.6 5.5 4.7e-08 -0.04 0.98 0.00 FALSE
9 GTEx Skin Sun Exposed Lower leg ZNF496 0.13 0.12 enet 17 0.14 2.4e-11 5.6 6.6 4.3e-11 -0.09 1.00 0.00 TRUE
10 GTEx Spleen ZNF496 0.31 0.35 lasso 2 0.32 4.1e-09 5.6 5.6 2.1e-08 -0.05 0.88 0.01 FALSE
11 GTEx Vagina ZNF670 0.32 0.01 enet 30 0.03 6.2e-02 -1.8 6.3 3.6e-10 -0.21 0.06 0.30 TRUE
12 YFS Blood NLRP3 0.30 0.07 enet 68 0.22 2.7e-71 10.3 11.7 1.7e-31 -0.49 0.03 0.97 TRUE
13 The Cancer Genome Atlas Breast Invasive Carcinoma NLRP3 0.02 0.02 enet 13 0.02 2.3e-04 -9.3 12.6 2.7e-36 -0.76 0.01 0.95 TRUE
14 The Cancer Genome Atlas Brain Lower Grade Glioma ZNF496 0.05 0.08 lasso 2 0.08 1.9e-09 5.6 5.3 1.1e-07 -0.04 0.01 0.99 FALSE
15 The Cancer Genome Atlas Prostate Adenocarcinoma ZNF496 0.04 0.03 blup 50 0.04 2.5e-05 5.3 5.2 1.9e-07 -0.05 0.02 0.97 FALSE