[Hub]/) : Traits : Blood White Count : ← →

chr1:246,449,849-248,302,707

Best TWAS P=2.73e-36 · Best GWAS P=7.33e-32 conditioned to 0.41

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
13	The Cancer Genome Atlas	Breast Invasive Carcinoma	NLRP3	0.02	0.02	enet	13	0.02	2.3e-04	-9.3	12.6	2.7e-36	-0.76	0.01	0.95	TRUE
12	YFS	Blood	NLRP3	0.30	0.07	enet	68	0.22	2.7e-71	10.3	11.7	1.7e-31	-0.49	0.03	0.97	TRUE
9	GTEx	Skin Sun Exposed Lower leg	ZNF496	0.13	0.12	enet	17	0.14	2.4e-11	5.6	6.6	4.3e-11	-0.09	1.00	0.00	TRUE
11	GTEx	Vagina	ZNF670	0.32	0.01	enet	30	0.03	6.2e-02	-1.8	6.3	3.6e-10	-0.21	0.06	0.30	TRUE
3	GTEx	Brain Cerebellum	ZNF496	0.26	0.13	enet	24	0.12	1.7e-04	-4.6	5.9	3.0e-09	-0.14	0.21	0.11	FALSE
5	GTEx	Breast Mammary Tissue (Female)	ZNF496	0.19	0.11	lasso	2	0.10	9.0e-04	5.6	5.6	2.1e-08	-0.05	0.08	0.05	FALSE
10	GTEx	Spleen	ZNF496	0.31	0.35	lasso	2	0.32	4.1e-09	5.6	5.6	2.1e-08	-0.05	0.88	0.01	FALSE
2	GTEx	Artery Tibial	ZNF496	0.14	0.11	lasso	3	0.12	2.6e-09	5.6	5.5	4.4e-08	-0.05	1.00	0.00	FALSE
8	GTEx	Pancreas	ZNF496	0.27	0.20	lasso	6	0.20	9.0e-09	5.6	5.5	4.7e-08	-0.04	0.98	0.00	FALSE
4	GTEx	Breast Mammary Tissue	ZNF496	0.15	0.16	lasso	4	0.13	4.0e-07	5.6	5.4	5.7e-08	-0.05	0.99	0.00	FALSE
6	GTEx	Cells Transformed fibroblasts	ZNF496	0.17	0.12	lasso	3	0.12	6.0e-09	5.6	5.4	6.9e-08	-0.05	1.00	0.00	FALSE
7	GTEx	Nerve Tibial	ZNF496	0.29	0.24	lasso	5	0.27	5.2e-19	5.6	5.3	8.7e-08	-0.05	1.00	0.00	FALSE
1	GTEx	Adipose Subcutaneous	ZNF496	0.24	0.12	lasso	7	0.14	1.1e-11	5.6	5.3	9.1e-08	-0.06	1.00	0.00	FALSE
14	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZNF496	0.05	0.08	lasso	2	0.08	1.9e-09	5.6	5.3	1.1e-07	-0.04	0.01	0.99	FALSE
15	The Cancer Genome Atlas	Prostate Adenocarcinoma	ZNF496	0.04	0.03	blup	50	0.04	2.5e-05	5.3	5.2	1.9e-07	-0.05	0.02	0.97	FALSE