Best TWAS P=6.4e-28 · Best GWAS P=3.15e-20 conditioned to 0.00431
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NTR | Blood | LAPTM5 | 0.06 | 0.04 | bslmm | 540 | 0.04 | 2.7e-12 | 6.3 | 6.8 | 9.2e-12 | 0.28 | 1.00 | 0.00 | FALSE |
2 | YFS | Blood | LAPTM5 | 0.09 | 0.04 | lasso | 5 | 0.09 | 1.9e-26 | 6.3 | 11.0 | 6.4e-28 | 0.64 | 0.12 | 0.88 | TRUE |