[Hub]/) : Traits : Blood White Count :

chr2:127,902,643-129,337,275

Best TWAS P=1.57e-08 · Best GWAS P=5.37e-07 conditioned to 0.112

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous POLR2D 0.15 0.01 lasso 5 0.01 6.4e-02 4.3 5.3 1.1e-07 0.76 0.06 0.55 FALSE
2 GTEx Artery Aorta POLR2D 0.18 0.03 enet 35 0.07 7.1e-05 4.9 5.5 3.5e-08 0.45 0.04 0.65 FALSE
3 GTEx Cells Transformed fibroblasts AMMECR1L 0.08 0.00 enet 17 0.00 1.6e-01 4.6 5.2 1.9e-07 0.32 0.04 0.35 FALSE
4 GTEx Colon Transverse AC006011.4 0.24 0.00 enet 21 0.02 3.6e-02 4.3 5.5 4.3e-08 0.57 0.05 0.35 FALSE
5 GTEx Esophagus Gastroesophageal Junction RP5-935K16.1 0.30 0.36 lasso 6 0.39 4.1e-15 4.5 -5.6 1.8e-08 -0.56 0.04 0.94 FALSE
6 GTEx Lung POLR2D 0.12 0.03 lasso 4 0.05 8.4e-05 4.5 5.2 1.7e-07 0.45 0.03 0.88 FALSE
7 GTEx Muscle Skeletal RP5-935K16.1 0.21 0.15 enet 16 0.19 9.4e-19 4.9 -5.2 2.0e-07 -0.52 0.02 0.96 FALSE
8 GTEx Testis RP5-935K16.1 0.45 0.34 enet 26 0.50 1.7e-25 4.5 -5.2 2.1e-07 -0.48 0.02 0.96 FALSE
9 The Cancer Genome Atlas Breast Invasive Carcinoma LIMS2 0.03 0.00 blup 56 0.01 1.4e-03 4.3 -5.7 1.6e-08 -0.68 0.01 0.29 TRUE