Best TWAS P=1.71e-10 · Best GWAS P=3.77e-33 conditioned to 3.33e-22
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | CAND2 | 0.34 | 0.08 | lasso | 14 | 0.13 | 8.1e-10 | -3.2 | -5.9 | 4.3e-09 | 0.40 | 0.76 | 0.19 | FALSE |
| 2 | GTEx | Nerve Tibial | MKRN2 | 0.12 | 0.00 | enet | 41 | 0.00 | 3.0e-01 | -2.8 | 5.4 | 5.7e-08 | -0.08 | 0.18 | 0.15 | TRUE |
| 3 | METSIM | Adipose | TSEN2 | 0.06 | 0.02 | enet | 30 | 0.06 | 9.3e-10 | -8.0 | 6.4 | 1.7e-10 | -0.57 | 0.48 | 0.51 | TRUE |