Hub : Genes

CAND2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Cells Transformed fibroblasts	0.3420	0.0740	1.4e-06	0.082	NA	0.097	NA	0.128	9.2e-07	NA	9.5e-08	NA	8.1e-10
2	GTEx	Muscle Skeletal	0.3418	0.0444	0.0e+00	0.286	NA	0.308	NA	0.308	3.3e-28	NA	1.2e-30	NA	1.0e-30
3	GTEx	Nerve Tibial	0.1195	0.0477	4.2e-03	0.005	NA	0.027	NA	0.006	1.3e-01	NA	4.9e-03	NA	1.1e-01
4	GTEx	Pituitary	0.3320	0.1070	5.6e-03	0.001	NA	-0.004	NA	0.015	3.0e-01	NA	4.1e-01	NA	1.3e-01
5	GTEx	Thyroid	0.2280	0.0590	3.3e-05	0.071	NA	0.083	NA	0.094	4.4e-06	NA	6.6e-07	NA	1.2e-07
6	METSIM	Adipose	0.1045	0.0354	3.5e-04	0.003	0.029	0.056	0.027	0.017	1.0e-01	2.7e-05	8.5e-09	4.6e-05	1.2e-03
7	ROSMAP	Brain Pre-frontal Cortex	0.0797	0.0323	4.5e-03	0.037	0.016	0.024	0.092	0.034	1.2e-05	3.2e-03	3.7e-04	7.0e-12	2.8e-05
8	TCGA	Breast Invasive Carcinoma	0.0304	0.0179	2.2e-03	0.004	0.013	0.010	NA	0.003	4.5e-02	8.6e-04	3.7e-03	NA	7.3e-02
9	TCGA	Kidney Renal Clear Cell Carcinoma	0.1574	0.0724	1.0e-04	0.053	0.031	0.050	NA	0.052	1.1e-06	1.7e-04	2.3e-06	NA	1.5e-06
10	TCGA	Kidney Renal Papillary Cell Carcinoma	0.2530	0.0840	2.6e-05	0.108	0.091	0.054	NA	0.095	1.0e-06	7.1e-06	4.6e-04	NA	4.6e-06
11	TCGA	Brain Lower Grade Glioma	0.1102	0.0409	5.9e-07	0.018	0.048	0.046	NA	0.040	3.1e-03	3.6e-06	5.0e-06	NA	2.4e-05
12	TCGA	Lung Squamous Cell Carcinoma	0.1010	0.0496	3.4e-03	0.027	0.006	0.014	NA	0.008	4.0e-04	5.6e-02	8.7e-03	NA	3.4e-02
13	TCGA	Pancreatic Adenocarcinoma	0.1040	0.0550	7.3e-03	-0.003	0.005	-0.005	NA	-0.003	4.5e-01	1.8e-01	6.0e-01	NA	4.8e-01
14	TCGA	Prostate Adenocarcinoma	0.0682	0.0312	2.2e-04	0.024	0.044	0.040	NA	0.043	1.2e-03	1.9e-05	4.4e-05	NA	2.6e-05
15	TCGA	Thyroid Carcinoma	0.1170	0.0450	2.1e-06	0.023	0.064	0.092	NA	0.075	2.4e-03	7.2e-07	2.8e-09	NA	8.3e-08

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Bipolar Disorder (2018)	0.5	0.8	3.0	0.2	1.1	-0.2	1.7	-1.0	-1.2	0.9	0.7	1.0	0.9	1.1	0.4	0.5	0.3	0.3
Bipolar Disorder or Schizophrenia	0.7	1.6	3.5	1.7	1.8	-0.9	0.9	-1.4	-0.9	1.1	1.0	1.5	1.5	1.9	0.9	1.5	0.6	0.1
Depressed Affect (Nagel 2018)	1.3	2.6	7.0	-0.3	-1.7	2.6	1.3	1.7	1.2	1.5	2.1	1.1	1.3	0.7	1.4	0.2	2.3	2.7
Depression (Nagel 2018)	1.0	1.4	3.9	-0.3	-1.3	1.9	1.6	1.3	2.0	1.4	0.9	0.7	0.6	0.1	0.6	-0.6	1.3	1.5
Intelligence (Savage-Jansen 2018)	0.5	1.5	5.5	-0.4	-1.8	1.7	-2.4	1.5	-0.4	-1.2	-0.8	0.5	0.6	0.1	0.9	0.0	1.5	1.7
Neuroticism (Nagel 2018)	0.6	1.5	6.3	0.7	-1.6	1.5	0.6	1.7	0.8	0.3	0.7	1.0	1.1	0.3	0.7	0.4	2.0	2.5
Schizophrenia (2018)	0.6	1.2	4.2	2.0	1.5	-1.0	-0.2	-1.0	-0.3	0.7	0.7	1.1	1.2	1.5	0.8	1.5	0.6	-0.1
Schizophrenia vs Biploar Disorder	0.7	0.9	3.7	0.4	-1.3	0.7	-1.1	1.1	1.9	-0.9	-0.8	-0.5	-0.2	-1.5	-0.3	-0.9	-0.2	0.1
Worry (Nagel 2018)	0.1	0.2	0.7	0.2	-0.4	-0.1	0.5	0.4	-0.5	-0.5	-0.3	0.0	0.3	-0.5	-0.7	0.1	0.2	0.8
Alzheimer’s Disease (in mother)	2.1	2.5	8.5	1.5	1.8	-1.6	0.4	-1.9	0.9	1.3	1.7	1.5	1.2	2.9	1.0	2.6	0.7	-0.5
Alzheimer’s Disease (in father)	0.5	0.5	3.6	1.9	0.4	-0.6	0.0	-0.2	-0.2	0.7	0.8	0.4	-0.1	0.8	0.4	0.8	1.0	0.4
Alzheimer’s Disease (including proxy)	1.5	2.2	7.2	2.7	1.1	-1.4	0.4	-1.2	0.9	1.2	2.2	1.4	0.9	2.3	0.7	2.2	1.1	-0.0
Crohns Disease (2017)	0.8	1.8	8.2	1.4	1.2	-1.2	2.9	-1.2	-0.1	0.9	1.9	0.9	0.8	1.9	0.4	1.4	0.7	0.2
Irritable Bowel Disease (IBD)	0.3	0.7	2.4	0.8	1.2	-1.0	1.6	-1.1	-0.6	0.6	1.1	0.3	0.4	1.3	0.3	0.8	0.4	0.1
Ulcerative Colitis (UC)	0.2	0.3	1.2	0.2	1.0	-0.7	-0.3	-0.8	-1.1	0.4	-0.3	-0.2	-0.1	0.8	0.3	0.1	0.1	-0.2
Major Depression (MDD)	0.5	0.6	1.5	-0.7	0.7	-0.2	-0.2	-0.8	1.2	-1.0	-0.9	-0.1	-0.5	-0.6	-0.8	-0.7	-1.2	-0.3
Reaction Time	0.3	0.5	3.4	-1.2	0.1	0.3	1.8	-0.2	0.3	1.2	0.2	-0.2	-0.1	0.2	-0.4	0.5	0.3	-0.3
Verbal and Numeric Reasoning (VNR)	0.3	0.6	3.7	-0.3	-0.5	0.1	-1.5	0.2	-0.4	-1.9	-1.2	-0.6	-0.2	-0.5	-0.1	-0.3	0.4	0.6
Breast Cancer	0.5	1.1	3.5	-0.3	1.5	-0.8	1.6	-1.6	-1.6	0.6	0.0	0.0	-0.6	-0.2	-1.9	0.3	-1.1	-1.0
Ovarian Cancer	0.3	0.4	1.8	-0.5	0.1	0.5	0.6	0.1	0.2	0.7	-0.5	-0.1	-0.6	-1.3	-1.2	-0.6	-0.5	0.1
Prostate Cancer	0.5	0.6	2.4	0.3	0.2	0.3	1.1	-0.2	-0.7	0.1	-0.6	-1.2	-1.5	-0.9	-0.6	-1.3	-1.0	-0.1
Age at First Birth	0.1	0.1	0.6	-0.1	-0.1	-0.1	-0.3	-0.1	0.3	0.1	-0.1	-0.1	-0.5	0.4	-0.1	0.4	0.8	0.3
Bipolar Disorder (2011)	0.7	0.7	2.4	1.3	1.0	-0.4	1.6	-0.7	-0.4	1.5	1.2	0.0	0.3	0.9	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.2	0.2	0.8	-0.1	0.3	-0.2	0.2	-0.4	0.8	0.9	0.5	0.2	0.6	0.5	0.4	-0.1	-0.4	-0.6
Coronary Artery Disease (CAD)	0.4	0.4	0.9	0.4	-0.8	0.9	0.2	0.9	0.8	0.4	0.8	0.8	0.9	-0.3	-0.0	-0.0	0.6	1.0
Crohns Disease (2012)	0.4	0.7	2.5	0.3	0.4	-0.3	1.6	-0.3	-0.2	-1.3	-0.5	-0.6	-0.3	-1.0	-1.3	-1.0	-0.9	-0.3
Mean Putamen Volume	0.4	0.4	1.7	-0.5	-0.8	1.1	1.3	0.8	0.3	0.1	0.4	-0.0	0.1	0.1	1.2	-0.0	0.4	0.2
Fasting Glucose	1.4	1.7	4.1	0.4	-2.0	1.6	-1.6	1.9	-0.1	-0.3	-0.3	1.4	1.9	-0.2	1.1	-0.3	1.1	2.0
HbA1C	0.4	0.4	1.4	-0.5	-1.2	-0.0	-0.9	0.9	0.6	-0.8	-0.1	0.3	0.4	-0.6	-0.1	-0.6	0.4	0.8
HDL Cholesterol	0.3	0.5	0.9	0.5	0.1	0.9	-0.4	0.4	-0.9	0.7	0.9	0.7	0.3	0.9	0.9	0.7	1.0	1.0
LDL Cholesterol	2.1	3.2	8.5	-2.1	-2.5	1.8	-1.6	1.9	-0.6	-1.7	-1.9	-2.3	-1.7	-2.3	-0.2	-2.9	-0.6	0.1
Lupus	0.6	0.9	3.0	0.9	1.1	-1.2	0.3	-1.0	-0.9	0.0	-0.2	0.9	1.1	1.7	0.8	1.1	0.8	0.5
Neuroticism (2016)	0.5	0.8	3.4	-1.8	-0.9	1.2	0.5	0.8	1.5	0.1	0.3	-0.7	-0.9	-0.4	-0.5	-1.0	-0.2	0.1
Primary Biliary Cirrhosis	0.3	0.4	1.0	0.7	-0.8	0.4	0.9	1.0	-1.0	0.4	0.3	0.5	0.5	0.3	0.4	-0.2	0.9	0.5
Rheumatoid Arthritis	0.6	0.8	3.2	1.1	0.9	-1.3	-0.4	-0.6	-1.8	0.2	0.3	0.6	1.1	0.9	0.6	1.2	0.2	-0.4
Schizophrenia (2014)	0.4	0.9	3.0	1.7	1.7	-1.5	0.7	-1.3	-0.2	0.8	0.3	0.5	0.3	0.8	-0.0	1.1	0.1	-0.7
Triglycerides	1.3	2.1	6.0	-2.0	-2.3	1.3	-0.5	1.9	1.2	-1.1	-1.3	-1.1	-0.8	-1.9	0.1	-2.4	-0.4	0.5
Type 2 Diabetes (T2D) (2012)	1.5	1.7	5.4	-0.8	-2.2	1.7	-0.7	2.3	2.2	0.4	-0.6	0.2	-0.1	-1.4	0.7	-0.9	0.8	1.4
Ulcerative Colitis	0.2	0.3	0.8	-0.4	0.9	-0.6	-0.2	-0.8	-0.8	-0.6	-0.9	-0.8	-0.3	-0.1	-0.1	-0.4	-0.4	-0.4
Blood Eosinophil Count	0.7	5.5	30.6	-5.5	1.1	-0.1	0.5	-0.6	-0.8	-2.0	-2.6	-3.2	-2.7	-1.8	-1.0	-2.4	-2.5	-2.1
Blood Platelet Count	0.6	7.2	53.1	-7.3	2.6	-1.6	2.7	-2.9	-0.8	-1.8	-0.8	-2.5	-1.7	0.2	-1.4	-0.6	-2.2	-3.0
Blood Red Count	0.3	3.1	7.1	0.9	2.3	-2.3	1.4	-2.2	0.1	-2.0	-2.5	-0.3	-0.6	-1.5	-2.7	-0.4	-2.3	-1.8
Blood White Count	1.2	9.0	34.5	-5.9	2.2	-1.9	2.3	-2.2	-0.5	-2.2	-2.5	-2.8	-2.1	-2.3	-3.7	-2.6	-4.0	-4.0
Heel T-Score	0.3	2.3	10.0	3.2	2.5	-2.3	-0.7	-1.9	0.5	1.0	0.4	1.2	0.9	1.2	0.1	1.5	-0.5	0.7
BMI	0.6	3.7	10.0	2.5	-1.7	2.5	1.7	2.1	2.4	2.8	3.2	1.6	1.1	-0.3	1.1	0.6	1.9	0.5
Height	0.9	17.8	48.2	-3.3	-6.9	6.9	-5.3	6.6	2.6	-2.8	-3.4	-1.1	-1.1	-5.1	0.9	-4.2	1.5	3.5
Waist Hip Ratio (WHR)	3.6	16.2	42.4	-6.4	-6.0	6.5	-1.8	5.9	1.9	-1.9	-3.4	-2.8	-1.5	-5.1	0.0	-5.4	0.3	1.7
Systolic Blood Pressure	0.8	4.1	13.0	-2.1	-1.0	0.5	-0.4	0.5	0.3	-2.5	-2.9	-2.6	-1.5	-3.3	-1.5	-3.6	-2.0	-1.2
Smoking Status	1.9	4.6	14.2	0.8	3.5	-3.4	3.0	-3.8	-0.2	1.1	1.9	0.7	0.4	2.7	-0.5	2.4	-0.6	-1.1
Allergy or Eczema	0.2	0.5	1.8	-0.5	0.4	-0.5	-1.3	-0.3	0.8	0.5	-0.1	-0.8	-0.6	1.3	1.3	0.4	0.4	-0.2
Cardiovascular Disease	0.7	2.5	6.5	-2.1	-2.2	2.1	-0.5	2.1	1.6	-0.8	-1.0	-0.9	-0.4	-2.0	1.3	-2.5	0.2	1.2
Hypothyroidism (self reported)	1.0	2.3	6.2	0.1	1.2	-1.6	2.5	-1.1	1.6	1.6	2.2	0.7	0.3	2.3	2.0	1.5	0.8	-0.1
Respiratory disease	0.6	1.3	5.2	-2.2	-0.5	0.7	-0.3	0.5	-2.3	-0.6	-0.8	-1.6	-1.4	-0.3	0.8	-1.5	-0.2	0.0
Type 2 Diabetes (T2D) (2018)	1.1	2.1	7.7	-2.8	-1.4	0.2	-0.6	1.1	1.2	-1.6	-0.8	-1.3	-1.2	-2.5	-0.8	-2.0	-1.1	-0.5
Lung FEV1/FVC ratio	0.4	2.1	4.3	-1.5	-1.2	1.6	-1.8	1.3	0.3	-1.7	-2.0	-1.6	-1.2	-1.8	-0.2	-2.1	-0.5	-1.3
Lung FVC	1.5	7.8	24.8	2.2	4.0	-5.0	3.1	-4.3	-2.4	1.4	2.6	-0.1	-0.5	3.6	-0.2	2.8	-0.9	-2.7
Neuroticism	0.9	2.2	7.8	-0.2	-2.4	2.8	1.3	2.2	1.4	-0.0	0.2	0.7	0.8	-0.7	-0.0	-0.6	1.6	2.4
Chronotype (morning person)	0.7	1.5	4.7	-0.1	1.5	-1.7	-0.0	-1.8	-0.6	-1.1	-0.8	-0.9	-0.6	-0.7	-1.4	-0.4	-1.9	-2.2
Hair Pigment	0.1	3.0	10.2	0.1	3.2	-2.9	1.6	-3.2	-1.1	-0.1	0.2	0.5	0.6	1.9	-0.4	1.4	-1.7	-1.8
Tanning	0.1	1.6	4.4	-1.4	2.1	-1.9	0.5	-2.0	-1.4	0.2	-0.0	-1.2	-1.4	0.2	-0.8	0.4	-1.3	-1.4
Hand grip strength (left)	0.5	1.4	4.9	-1.5	1.7	-1.5	2.2	-1.8	1.8	0.2	0.6	-0.0	-0.1	0.5	0.0	0.3	-1.2	-0.1
Number of treatments/medications taken	0.6	1.1	2.7	-1.1	0.3	-0.4	-0.8	-0.2	0.6	-1.6	-1.6	-1.6	-1.5	-0.9	-0.2	-1.5	-0.8	-0.9
Average weekly spirits intake	0.3	0.4	1.8	-0.0	0.0	-0.3	0.2	-0.3	1.4	1.2	1.1	-0.2	-0.0	0.3	0.6	0.4	0.0	-0.2
Sensitivity / hurt feelings	0.4	0.7	2.7	-0.3	-0.8	0.8	1.6	0.6	0.5	-1.0	-0.9	-0.4	-0.9	-0.8	-1.3	-0.8	0.0	-0.0
Frequency of depressed mood in last 2 weeks	1.4	1.9	4.2	0.2	-1.2	1.7	1.2	1.3	1.4	1.6	1.5	1.4	1.2	1.2	1.6	0.1	1.8	2.0
Hearing difficulty/problems: Yes	0.3	0.5	1.3	0.7	-0.9	1.2	0.7	1.1	0.6	-0.5	-0.4	0.3	-0.3	-0.2	0.4	-0.4	0.7	0.9
Relative age of first facial hair	1.6	3.3	13.7	-0.2	-3.0	3.7	-0.7	3.2	-1.0	-0.5	0.4	1.5	1.1	-1.2	0.9	-0.8	1.3	2.7
Other serious medical condition/disability diagnosed by doctor	1.2	1.5	5.5	-0.2	2.3	-2.0	1.6	-2.3	0.8	0.3	-0.2	0.1	-0.5	1.1	-1.5	0.0	-0.9	-0.6
Ever used hormone-replacement therapy (HRT)	0.5	0.6	2.0	-0.7	-1.4	0.8	0.1	1.1	1.3	-0.7	-0.0	0.5	0.6	-1.0	-0.4	-0.4	0.1	1.0
Ever had hysterectomy (womb removed)	0.3	0.4	1.6	-1.0	-0.5	0.3	0.6	0.4	-0.6	-0.3	-0.7	-0.7	-0.4	-0.5	0.3	-1.3	-0.1	-0.1
Systolic blood pressure, automated reading	0.7	2.0	4.7	-0.6	-2.0	1.7	-0.3	1.8	1.6	-1.8	-1.7	-0.8	-0.1	-2.2	-0.1	-2.0	-0.3	0.6
Eye problems/disorders: Diabetes related eye disease	2.0	2.2	7.4	-0.0	-1.6	1.4	0.2	1.8	1.9	0.3	0.6	2.5	2.3	-0.7	-0.5	0.3	1.2	2.7
Angina	0.7	0.9	2.2	0.9	-1.5	1.4	0.2	1.5	1.4	0.5	0.5	0.8	0.2	-0.3	0.3	0.0	1.3	1.3
Medication for hormone replacement therapy	0.4	0.4	1.7	0.1	-0.4	-0.4	-0.9	0.4	0.9	-1.3	-1.1	-0.2	-0.1	-0.6	-0.6	-0.7	-0.4	-0.2
Vitamin and mineral supplements	0.5	0.7	2.6	-0.4	-1.3	1.6	0.2	0.9	0.7	0.3	-0.3	-0.4	0.5	-1.1	0.1	-1.6	-0.4	-0.0
Supplements: Zinc	1.6	1.7	6.3	-0.2	2.0	-2.5	0.3	-2.3	-1.1	-0.7	-0.9	-0.8	-1.2	0.7	-0.6	0.6	-1.4	-1.3
Medication: Co-codamol	0.3	0.3	1.5	0.1	-0.5	0.1	-0.6	0.1	0.1	0.4	1.2	0.3	0.4	0.5	1.0	0.3	0.5	0.6
Medication: Metformin	2.1	2.9	8.5	-1.9	-2.3	1.8	-0.8	2.2	1.4	-1.8	-1.5	-0.9	-0.9	-2.9	-1.0	-2.7	-0.5	0.4
Diabetes (father)	0.6	0.7	2.4	0.6	-0.4	-0.1	-0.3	0.5	0.5	0.6	0.6	1.4	1.6	0.7	1.0	0.7	1.2	1.2
Diabetes (mother)	0.8	1.0	4.8	-1.3	0.0	-0.3	-2.2	0.1	-1.8	-0.9	-1.2	-0.2	-0.4	-1.2	-0.5	-1.0	-0.8	-0.1
Severe depression (siblings)	0.7	0.8	6.0	-0.8	0.8	-0.2	2.5	-1.0	0.4	0.8	0.7	-0.4	-0.5	-0.0	-0.4	-0.3	-1.0	-0.5
Pack years adult smoking proportion	0.6	0.9	2.5	0.1	0.3	0.4	1.1	-0.4	1.6	0.2	-0.6	-1.2	-1.1	-1.1	-1.5	-1.3	-1.0	-0.7
Impedance of leg (right)	0.5	2.5	7.7	0.4	2.7	-2.0	0.6	-2.5	-0.7	0.9	1.1	0.8	0.7	2.8	-0.4	2.6	-0.0	-1.0
Leg fat-free mass (left)	0.8	4.4	15.3	0.1	-3.7	3.9	-0.2	3.6	2.3	1.0	0.9	1.0	0.8	-2.1	1.2	-1.2	1.7	2.1
Trunk fat percentage	1.8	7.0	18.6	2.3	-2.5	4.3	0.1	3.0	1.7	3.5	3.7	2.6	2.4	0.8	2.5	1.5	3.5	1.9
Hand grip strength (right)	1.0	2.9	8.3	-1.0	2.5	-2.3	2.9	-2.6	1.9	1.2	1.8	0.5	0.4	1.7	0.4	1.5	-0.9	-0.6
Townsend deprivation index at recruitment	1.6	2.2	7.6	-0.4	-1.7	1.5	-0.0	1.5	0.7	-1.7	-2.2	-0.4	-1.1	-2.8	-2.3	-1.7	-0.1	0.8
Current tobacco smoking	2.1	3.4	10.6	0.3	3.0	-2.9	2.8	-3.2	0.5	1.8	1.3	0.2	-0.2	2.0	-0.6	1.7	-0.9	-1.3
Average weekly fortified wine intake	0.6	0.7	2.3	0.2	0.6	-0.6	-1.1	-0.6	0.9	0.5	0.3	0.4	0.4	1.5	1.2	1.4	0.9	0.2
Maternal smoking around birth	0.4	0.6	4.6	2.1	0.5	-0.9	-0.8	-0.5	0.7	0.3	0.0	0.7	0.2	0.6	0.0	0.9	0.6	-0.1
Fed-up feelings	0.4	0.7	3.1	-0.5	-0.6	1.8	1.1	0.7	0.6	0.4	-0.1	0.6	0.7	-0.2	0.1	-1.1	0.3	1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	2.9	-0.4	-1.0	1.5	1.7	0.8	-0.2	0.4	-0.1	-0.5	-0.4	0.2	1.2	-1.4	0.8	0.8
Relative age voice broke	1.0	1.6	4.9	0.9	-2.1	1.9	-0.4	2.2	-0.6	0.9	0.9	1.3	1.0	-0.2	0.7	-0.0	1.6	1.6
Taking other prescription medications	0.9	1.5	5.5	-1.3	1.5	-1.5	0.1	-1.6	-0.1	-0.9	-0.6	-1.8	-2.4	0.3	-0.0	-0.8	-0.8	-1.3
Age when periods started (menarche)	0.1	0.2	0.7	-0.1	-0.3	0.4	-0.3	-0.0	0.0	-0.6	0.5	-0.0	-0.2	0.8	0.8	0.6	0.4	0.2
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.9	-0.3	1.2	-1.2	1.4	-1.4	-0.6	0.1	-0.1	0.0	-0.0	1.0	0.3	-0.3	-0.6	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	2.5	1.6	0.2	-0.5	-0.8	0.3	-0.2	0.8	0.6	1.0	0.9	0.7	0.9	0.8	0.7	0.6
Tinnitus: Yes, but not now, but have in the past	1.7	1.8	4.7	1.2	-0.8	0.6	1.2	0.6	1.9	1.0	1.9	2.2	1.6	1.1	0.3	0.9	1.6	1.5
Qualifications: CSEs or equivalent	0.9	1.1	3.8	0.5	-0.2	0.5	-1.3	0.5	0.9	0.3	0.9	1.4	1.7	1.4	2.0	1.1	1.0	0.5
Serious illness, injury or assault to yourself	2.2	2.7	7.7	0.7	2.8	-2.7	1.3	-2.8	0.7	0.9	1.1	1.2	1.6	2.2	-0.6	2.0	-0.6	-0.1
High blood pressure	0.8	2.2	6.5	-0.9	-2.3	1.9	-0.7	2.2	1.0	0.7	0.1	1.1	1.4	-0.3	1.8	-0.7	1.5	2.5
Hayfever, allergic rhinitis or eczema	0.6	1.3	2.8	0.5	-0.2	0.1	-1.6	0.5	1.1	1.3	0.8	0.5	0.9	1.6	1.7	1.6	1.6	0.9
Multivitamins +/- minerals	0.7	0.8	4.4	-0.1	1.7	-2.1	-0.3	-1.4	-0.6	-0.5	0.0	-0.1	-0.4	0.7	-0.5	1.0	-0.5	-0.6
Stomach or abdominal pain in last month	2.7	3.3	8.3	-0.7	1.5	-2.0	-0.8	-1.5	-1.4	-1.4	-2.2	-2.9	-2.6	-0.8	-1.1	-1.8	-2.0	-2.6
Supplements: Glucosamine	0.3	0.4	2.2	0.3	0.2	-0.9	-1.2	-0.2	-1.0	0.0	0.5	0.1	-0.2	0.6	1.5	0.4	0.0	0.5
Diverticular disease/diverticulitis (self-reported)	1.5	1.7	4.1	-1.7	0.1	-0.1	0.8	-0.4	-2.0	-1.4	-1.5	-1.5	-1.4	-1.4	-1.5	-1.2	-1.5	-1.4
Medication: Atenolol	0.7	0.9	4.0	-1.6	-1.2	2.0	1.1	1.2	0.5	0.1	-0.1	-0.0	-0.0	-0.5	0.5	-0.8	0.4	1.0
Medication: Levothyroxine sodium	2.0	3.4	11.1	0.7	0.1	-0.8	1.4	-0.0	2.1	2.6	3.3	2.2	1.9	2.2	1.6	2.2	1.9	1.1
Sitting height	0.8	5.8	17.2	-0.3	-4.0	4.1	-1.0	4.1	2.0	0.6	0.5	1.7	1.5	-1.2	1.4	-0.4	2.8	3.7
Chronic bronchitis/emphysema (father)	1.2	1.4	3.3	-0.5	0.4	-0.7	-0.2	-0.8	-1.3	-1.7	-1.3	-1.7	-1.5	-0.9	-1.0	-1.1	-1.3	-1.8
High blood pressure (mother)	2.1	3.0	9.2	0.2	-2.9	2.8	0.4	3.0	1.8	0.8	0.2	1.5	1.7	-0.7	0.3	-0.1	2.2	2.1
Body mass index (BMI)	0.6	2.5	6.8	1.5	-1.3	2.4	1.4	1.6	1.4	2.6	2.6	1.4	1.1	-0.0	1.2	0.4	1.5	0.6
Impedance of leg (left)	0.5	2.4	8.1	0.3	2.9	-2.1	0.3	-2.6	-0.6	0.6	1.0	0.3	0.5	2.7	-0.4	2.4	-0.1	-1.2
Leg predicted mass (left)	0.8	4.2	14.6	0.1	-3.6	3.8	-0.3	3.6	2.4	1.0	0.8	0.9	0.8	-2.1	1.2	-1.2	1.7	2.1
Trunk fat mass	1.4	6.2	22.6	1.4	-3.2	4.8	-0.1	3.6	2.2	2.6	2.9	1.9	1.8	-0.4	2.3	0.4	3.0	2.0
Waist circumference	1.3	4.6	22.0	-0.9	-3.4	4.7	0.6	3.7	2.2	1.3	0.9	0.4	0.6	-2.2	0.9	-1.8	1.7	1.4
Number of incorrect matches in round	1.1	1.7	6.0	-0.5	0.5	-0.6	0.1	-0.6	-0.9	-1.5	-1.6	-2.5	-2.1	-0.7	0.2	-1.5	-1.5	-2.0
Past tobacco smoking	1.2	2.1	6.2	0.9	-2.3	2.0	-0.8	2.5	2.0	1.3	1.0	1.0	1.0	-0.2	1.2	0.5	1.7	1.3
Alcohol usually taken with meals	0.7	1.2	4.4	-1.1	-1.3	1.3	0.6	1.2	-0.1	-1.0	-1.3	-0.8	-0.7	-2.1	-0.8	-1.5	-0.4	0.0
Nervous feelings	0.4	0.7	2.1	-0.6	-1.0	0.8	0.0	0.9	-1.0	-1.0	-1.4	-0.8	-0.6	-1.1	-0.8	-1.1	0.0	0.6
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.4	1.9	0.5	-0.0	0.4	0.2	0.1	0.7	0.5	0.1	0.3	0.4	1.2	1.4	-0.3	0.6	0.7
Hearing difficulty/problems with background noise	1.5	2.4	8.0	1.5	-0.3	0.6	-0.6	0.4	-0.1	0.9	1.0	1.8	1.5	2.6	2.8	1.5	2.0	2.1
Hair/balding pattern: Pattern 2	2.9	3.7	11.2	2.4	2.5	-2.8	0.6	-2.5	0.4	1.9	1.8	0.5	0.6	3.3	1.6	2.4	0.5	-1.5
Had menopause	0.8	1.0	2.2	-0.9	-1.4	1.1	0.3	1.3	0.2	-0.6	-1.1	-1.0	-1.1	-1.5	-0.3	-1.5	0.0	0.3
Had other major operations	0.6	0.8	2.5	0.4	0.9	-1.6	1.2	-0.9	0.9	0.8	0.2	1.0	0.9	0.9	-0.7	0.6	0.1	0.8
Forced vital capacity (FVC)	0.3	1.0	2.7	1.5	0.0	-0.7	1.1	-0.1	-0.1	0.8	1.6	0.5	0.3	1.6	1.4	1.2	0.9	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	1.3	1.2	0.6	-0.7	-0.4	-0.1	0.4	0.3	-0.2	0.4	0.1	0.1	-0.3	0.1	-0.1	0.2
Ever unenthusiastic/disinterested for a whole week	1.5	1.8	6.1	0.6	0.8	-0.7	0.5	-1.0	-1.4	1.4	1.1	1.6	1.7	2.5	1.3	1.9	1.2	0.9
Qualifications: None of the above	0.3	0.6	2.1	0.1	0.0	-0.6	0.8	-0.6	0.0	-0.4	-0.4	-1.3	-0.9	-0.5	-0.9	-0.9	-0.9	-1.5
Financial difficulties in last 2 years	0.6	0.8	2.4	1.3	-0.1	0.0	1.5	0.2	0.9	1.3	0.9	0.9	0.7	1.1	0.5	0.8	1.0	0.6
Mouth/teeth dental problems	0.9	1.3	3.9	0.9	1.5	-2.0	0.0	-1.5	0.1	1.1	1.0	0.4	0.6	1.9	0.3	1.8	0.2	-1.0
Heart attack	0.7	0.8	2.5	-0.3	0.7	-0.2	0.9	-0.6	-1.0	-1.6	-1.2	-0.9	-1.3	-0.7	-0.8	-1.1	-0.9	-0.1
Allergy	0.2	0.4	1.9	0.9	0.3	-0.1	1.4	-0.3	0.3	-0.3	0.0	0.7	0.0	-0.5	-1.2	-0.4	-0.6	-0.2
Pain all over the body in last month	0.4	0.4	1.6	1.2	-0.5	0.8	0.4	0.6	0.3	0.4	0.2	0.5	0.1	0.5	0.5	0.2	1.1	1.0
Diabetes (self-reported)	1.2	1.8	6.9	-1.5	-2.6	1.4	-0.3	2.5	1.4	-0.6	-0.2	-0.1	-0.3	-1.6	0.6	-1.6	0.7	1.2
Hayfever/allergic rhinitis (self-reported)	0.8	1.0	3.9	0.6	-0.2	0.1	1.2	0.3	-0.7	1.8	2.0	0.4	0.5	1.2	1.1	0.3	1.1	1.0
Medication: Ramipril	0.5	0.7	2.0	0.6	-1.3	1.1	-0.4	1.4	1.0	0.2	-0.3	0.1	0.4	-0.5	1.0	-0.0	1.1	0.9
Medication: Simvastatin	0.8	1.1	5.5	-1.3	-1.4	1.4	-0.8	1.2	2.3	-0.3	0.2	-0.4	-0.2	-1.4	0.1	-1.2	-0.1	0.2
Fluid intelligence score	0.1	0.3	1.4	-0.3	-0.3	0.0	-1.2	0.2	-0.7	-0.7	-0.1	-0.2	-0.0	0.3	0.7	0.4	0.6	0.5
Illnesses of siblings	1.1	1.6	6.4	-1.3	2.5	-1.5	-0.3	-2.3	-0.0	-0.2	-0.2	0.6	0.4	0.8	-1.7	1.3	-1.1	-0.9
Neuroticism score	0.4	0.9	3.7	-0.3	-1.6	1.9	0.8	1.5	-0.4	-0.5	-0.2	0.1	0.2	-0.4	0.1	-0.8	1.0	1.5
Weight	1.0	5.0	20.9	0.3	-3.5	4.6	0.5	3.7	2.5	1.8	1.7	1.1	0.9	-1.5	1.7	-0.7	2.1	1.8
Impedance of arm (right)	0.9	4.2	10.3	1.1	-1.8	3.2	-2.1	2.5	-1.1	1.0	0.8	2.5	2.0	1.1	1.6	1.7	2.9	2.9
Arm fat percentage (right)	1.4	5.7	17.1	1.8	-2.4	4.1	0.4	2.9	1.1	3.1	3.3	2.6	2.2	0.3	2.3	1.0	2.8	1.9
Trunk fat-free mass	0.6	3.5	10.3	-1.9	-3.0	2.6	0.2	2.5	2.1	-0.9	-1.2	-1.0	-0.9	-3.2	0.1	-2.7	-0.3	0.7
Hip circumference	1.1	4.7	13.7	2.6	-1.4	2.4	1.7	1.7	1.3	3.1	3.7	2.6	2.2	0.7	1.6	1.4	2.4	1.5
Time employed in main current job	0.3	0.4	1.3	-0.4	-1.1	0.9	0.2	1.1	-0.8	-0.2	-0.3	-0.3	-0.0	-0.9	-0.2	-0.7	0.5	0.1
Alcohol intake versus 10 years previously	0.7	1.1	3.6	0.6	1.5	-1.9	0.7	-1.4	0.5	-0.5	-0.4	-0.1	-0.7	-0.5	-1.6	-0.6	-1.6	-1.2
Father’s age at death	0.2	0.3	2.4	-0.3	0.3	-0.5	-0.1	-0.6	-1.6	0.2	0.6	0.0	-0.0	0.2	-0.3	0.3	-0.6	-0.2
Worrier / anxious feelings	0.4	0.8	2.5	-1.6	-0.9	0.8	-0.0	0.8	-0.5	-1.6	-0.8	-0.7	-0.6	-1.1	0.1	-1.3	-0.6	0.2
Frequency of tiredness / lethargy in last 2 weeks	2.3	3.8	14.6	0.2	-3.1	3.8	-1.4	3.3	-0.3	-0.9	-1.5	0.1	0.4	-1.7	0.7	-2.4	1.4	2.4
Falls in the last year	1.1	1.4	6.2	0.2	-1.4	2.2	-2.5	1.5	0.1	-0.6	-1.5	-0.0	0.4	-0.7	0.4	-1.0	0.5	1.2
Hair/balding pattern: Pattern 3	1.0	1.5	3.3	-0.6	-1.8	1.6	-0.8	1.7	1.2	-1.4	-1.6	-0.4	-0.4	-1.8	-0.7	-1.1	0.2	0.9
Number of live births	0.7	0.9	1.7	1.2	-0.3	0.7	-0.1	0.6	1.0	1.0	1.3	1.2	0.9	1.1	1.1	1.1	1.2	0.9
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	2.3	1.4	-0.4	-0.2	0.8	0.3	-0.4	0.7	1.5	0.4	0.4	1.3	1.5	1.0	0.9	0.0
Pulse rate	1.7	2.9	9.5	-0.3	2.5	-3.1	-0.5	-2.7	-1.0	-0.5	0.3	-1.9	-1.6	0.5	-0.9	0.1	-1.8	-2.8
Happiness	1.1	1.3	5.4	-0.0	-1.3	1.6	0.9	1.3	0.2	0.8	1.0	1.4	1.2	0.4	0.9	0.0	1.5	2.3
Noisy workplace	0.4	0.5	1.5	-0.1	-1.0	0.9	-0.1	1.0	-0.2	-1.0	0.3	1.2	1.1	-0.5	0.1	-0.1	0.2	0.9
Qualifications: A levels/AS levels or equivalent	0.6	1.2	4.7	0.6	0.2	-0.2	-0.2	-0.1	1.1	0.8	1.1	1.7	1.8	1.0	0.5	1.3	1.1	2.2
Serious illness, injury or assault of a close relative in last 2 years	2.6	3.0	6.7	2.1	-1.0	0.5	0.4	1.0	1.7	1.4	1.4	1.8	1.6	2.1	2.5	2.2	2.6	2.0
Mouth/teeth dental problems: Dentures	0.6	1.0	3.0	-1.0	0.0	0.3	1.2	-0.3	-1.2	-0.5	-0.9	-1.7	-1.2	-1.0	-0.5	-1.4	-1.1	-0.8
Asthma	0.8	1.7	7.6	-2.8	-0.7	0.5	-1.1	0.4	-2.0	-1.3	-0.6	-1.7	-1.0	-0.7	1.2	-1.8	-0.4	-0.1
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	0.7	0.7	0.9	-0.9	-0.0	-0.8	0.6	-0.7	-0.3	-0.3	-0.5	-0.1	-0.1	0.2	-0.7	-0.7
Medication: Cholesterol lowering	3.7	5.8	16.6	-3.2	-1.1	1.5	0.1	0.9	2.0	-2.3	-2.0	-3.0	-2.9	-3.8	-1.7	-4.1	-2.2	-1.3
Depression (self-reported)	1.1	1.4	4.8	-0.3	-0.1	0.1	1.0	0.1	2.0	2.2	1.8	1.4	1.3	1.1	0.1	0.4	1.2	1.1
Medication: Lansoprazole	0.7	0.8	3.4	0.8	-0.3	-0.1	-1.8	0.2	-1.2	-0.8	-0.3	-1.0	-0.4	0.7	1.9	0.0	0.8	0.0
Prospective memory result	0.2	0.2	0.9	-0.5	-0.0	0.4	-0.3	0.1	-1.0	0.1	-0.1	-0.2	-0.5	-0.0	0.7	-0.6	-0.7	-0.4
Lung cancer (father)	0.1	0.2	0.8	0.5	0.1	-0.0	0.3	-0.4	-0.3	0.7	0.7	-0.0	-0.1	0.0	-0.2	0.2	0.0	-0.9
Illnesses of mother	3.3	4.1	7.7	-0.2	2.0	-2.4	-0.7	-2.2	-1.7	-2.5	-1.6	-2.7	-2.7	-1.1	-1.4	-1.2	-2.7	-2.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.1	2.7	1.2	-0.1	-0.3	1.3	0.1	-0.6	1.6	1.6	0.9	0.9	1.5	0.9	1.4	0.9	0.4
Pulse wave Arterial Stiffness index	1.9	2.3	5.8	-1.4	0.7	-1.3	-1.7	-0.9	-0.9	-1.9	-2.4	-1.4	-0.9	-1.6	-1.7	-1.7	-1.9	-1.2
Impedance of arm (left)	0.6	2.9	6.2	0.8	-1.3	2.3	-1.9	1.8	-1.1	0.8	0.9	1.9	1.8	1.4	1.6	2.0	2.5	2.3
Arm fat mass (right)	1.3	5.1	17.0	1.1	-2.8	4.1	0.5	3.1	1.9	2.7	3.0	2.1	1.8	-0.4	2.0	0.3	2.5	1.9
Trunk predicted mass	0.6	3.5	10.5	-2.0	-2.9	2.6	0.3	2.5	2.0	-1.0	-1.2	-1.0	-1.0	-3.2	0.0	-2.8	-0.3	0.7
Standing height	0.9	9.1	28.5	-2.6	-5.2	5.3	-2.2	5.0	2.8	-1.4	-1.8	-0.6	-0.5	-3.6	1.1	-2.6	1.5	2.8
Length of working week for main job	1.1	1.2	3.6	0.2	-1.3	1.9	1.5	1.3	0.7	0.4	0.4	0.9	0.6	-0.0	1.8	-0.6	0.8	1.7
Exposure to tobacco smoke at home	1.1	1.2	4.1	0.6	-0.1	-0.3	-0.6	0.0	1.3	0.7	1.3	2.0	1.8	0.8	0.3	1.4	1.3	1.5
Breastfed as a baby	0.3	0.3	0.8	0.2	-0.5	0.4	-0.9	0.7	-0.4	-0.9	-0.8	0.6	0.2	0.2	0.3	0.4	0.7	0.7
Tense / ‘highly strung’	0.1	0.2	0.9	0.5	0.2	-0.6	0.3	-0.3	0.4	-0.2	-0.3	0.3	0.2	0.1	-0.9	0.5	0.1	0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	4.8	0.8	-0.8	1.3	-0.2	1.0	-0.5	0.4	-0.5	-0.2	-0.0	1.1	2.2	-0.1	1.7	1.8
Hair/balding pattern: Pattern 4	0.2	0.5	1.2	-1.1	0.9	-0.5	0.9	-0.9	-0.4	0.2	-0.2	-0.7	-0.8	-0.2	-0.8	-0.4	-0.8	-0.9
Birth weight of first child	0.3	0.5	1.6	1.1	0.4	-1.2	0.6	-0.5	0.2	0.4	1.1	-0.6	-0.3	-0.1	0.8	0.0	-0.1	-1.0
Peak expiratory flow (PEF)	0.3	0.8	2.4	0.4	-1.5	1.4	-1.4	1.5	-1.2	-0.1	0.4	-0.2	0.4	-0.3	0.9	-0.2	0.7	0.1
Pulse wave reflection index	0.7	0.9	3.6	-1.6	-0.8	0.5	-1.9	0.4	-1.1	-0.9	-1.0	-0.1	0.2	-1.3	-0.4	-1.0	-0.6	-0.2
Ever highly irritable/argumentative for 2 days	0.7	0.8	2.3	-0.8	0.0	0.2	-0.3	0.1	-0.8	-0.5	-1.3	-1.0	-1.4	-0.9	-1.5	-1.0	-0.7	-0.9
Loud music exposure frequency	0.2	0.2	0.7	0.7	-0.3	-0.2	0.8	0.3	-0.8	0.0	0.6	0.2	-0.2	0.5	-0.4	0.6	0.6	-0.3
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	2.9	-0.2	-0.3	0.7	-1.7	0.4	-0.8	-0.1	-0.8	0.3	0.1	-1.4	-1.4	-0.2	-0.1	1.1
Mouth/teeth dental problems: Bleeding gums	1.2	1.5	4.3	0.4	-1.3	1.6	-0.2	1.6	0.9	0.9	1.0	1.9	1.7	0.3	0.3	0.5	1.2	2.1
Blood clot in the leg (DVT)	0.2	0.3	1.5	0.3	-0.7	1.2	0.6	0.9	-0.1	0.2	-0.1	0.5	0.5	-0.6	0.1	-0.3	0.4	0.7
Medication: Paracetamol	0.4	0.7	2.3	1.3	0.3	-0.5	0.7	-0.5	0.0	0.4	1.0	1.3	1.5	0.8	-0.4	1.2	0.5	0.4
Headache pain in last month	0.4	0.6	2.1	0.2	-0.8	1.1	-1.1	0.7	1.4	-0.2	-0.8	-0.6	-0.6	-0.8	0.2	-1.3	0.0	0.4
Medication for cholesterol, blood pressure or diabetes	2.3	3.8	10.1	1.7	2.5	-2.3	1.5	-2.4	-2.4	1.3	1.8	1.7	1.4	2.9	0.2	3.2	0.2	-0.2
Glaucoma (self-reported)	0.6	0.7	2.0	-0.1	1.3	-0.8	0.3	-1.1	-1.4	0.5	-0.4	-0.9	-0.8	0.7	-0.3	0.3	-0.6	-1.4
Gout (self-reported)	0.4	0.6	2.0	1.4	-0.6	-0.5	0.1	0.3	-0.9	-0.1	-0.0	-1.0	-1.2	-0.9	-0.6	-0.6	-0.3	-0.8
Hypothyroidism/myxoedema (self-reported)	1.5	2.9	7.7	1.0	0.9	-1.3	2.0	-0.8	2.5	2.3	2.8	1.3	0.7	2.3	1.9	2.0	1.3	0.3
Medication: Amlodipine	0.9	1.3	4.0	-0.1	0.5	-0.7	-0.8	-0.8	0.3	-0.6	-1.5	-1.4	-1.3	-1.4	-2.0	-1.2	-1.3	-1.5
Medication: Ventolin 100micrograms inhaler	0.8	1.0	7.8	-0.4	-0.0	0.4	-2.8	0.0	-1.3	-0.6	-0.3	-0.9	-0.4	0.5	1.7	-0.8	0.3	0.1
Birth weight	1.9	4.2	9.9	2.0	-0.0	-0.1	-0.2	0.0	-0.8	2.8	2.9	2.5	2.0	3.1	2.5	2.9	2.5	1.2
Chronic bronchitis/emphysema (mother)	2.5	3.0	6.1	2.2	-1.5	1.7	-0.5	2.0	2.5	2.3	1.4	1.4	1.3	1.0	1.6	0.9	2.1	2.1
High blood pressure (siblings)	0.5	0.7	2.7	1.4	-1.4	0.3	-0.3	1.2	-0.0	0.9	1.1	0.0	0.1	0.3	1.6	-0.0	1.0	0.6
Forced vital capacity (FVC), Best measure	0.3	1.1	2.9	1.2	0.0	-0.4	1.5	-0.1	-0.7	1.4	1.5	0.6	0.6	1.7	1.1	1.4	0.9	0.5
Body fat percentage	1.4	5.4	14.0	2.1	-1.6	3.5	0.6	2.0	1.5	3.5	3.7	2.5	2.3	1.0	2.1	1.6	2.8	1.3
Leg fat percentage (right)	0.7	2.6	9.5	1.4	0.2	1.5	2.0	0.1	1.2	3.0	3.1	1.7	1.3	1.2	0.9	1.3	1.2	-0.2
Arm fat-free mass (right)	0.3	1.6	8.1	-0.9	-1.8	1.4	0.9	1.4	2.9	0.3	0.3	-0.6	-0.5	-1.9	0.0	-1.5	0.1	0.1
Exposure to tobacco smoke outside home	0.2	0.2	0.7	0.3	-0.6	0.5	-0.7	0.5	-0.3	0.0	-0.5	0.6	0.4	-0.3	-0.3	-0.2	0.3	0.8
Comparative body size at age 10	0.4	1.1	4.4	1.1	1.4	-1.2	0.7	-1.4	2.1	1.3	1.3	0.1	-0.5	0.8	-0.1	1.1	-0.0	-0.5
Number of full brothers	3.8	4.8	12.3	3.5	-0.3	0.7	0.2	0.6	0.2	3.1	3.0	2.8	2.8	2.2	1.5	2.3	2.9	1.7
Worry too long after embarrassment	0.8	1.4	5.7	1.3	-1.0	1.0	1.4	1.2	0.4	0.2	0.6	1.5	0.8	0.7	0.7	1.2	1.6	2.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	2.3	-1.0	-0.2	0.7	-0.3	0.2	-1.5	-1.3	-1.4	-1.5	-1.3	-0.1	0.9	-1.2	0.0	-0.1
Wheeze or whistling in the chest in last year	1.7	3.0	8.3	-2.4	-1.3	1.2	-0.3	1.1	0.5	-2.5	-2.0	-2.1	-2.2	-2.2	0.2	-2.9	-1.1	-0.1
Number of children fathered	0.6	0.7	2.2	-0.1	0.8	-0.3	-1.3	-0.8	-1.5	-0.4	-1.4	-0.4	0.1	0.7	1.3	-0.4	-0.2	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.9	2.2	0.0	1.4	-0.7	0.6	-1.4	-0.2	-0.9	-1.1	-0.6	-0.4	-0.5	-1.4	-0.5	-1.5	-1.0
Age at first live birth	0.8	1.4	3.7	0.5	1.0	-1.6	1.6	-1.0	-1.1	0.7	1.9	0.2	0.2	1.9	1.1	1.4	0.3	-0.9
Pulse wave peak to peak time	2.2	2.6	6.0	1.4	-1.0	1.6	1.3	1.2	1.0	2.1	2.5	1.6	1.1	1.5	1.8	1.7	2.1	1.5
Health satisfaction	0.4	0.5	1.5	0.1	0.4	-0.0	1.2	-0.2	-0.6	1.1	0.9	0.6	0.4	0.9	0.5	0.7	0.8	0.6
Shortness of breath walking on level ground	0.8	0.9	4.0	-0.9	1.1	-0.6	0.6	-0.9	-0.8	-0.8	-1.1	-0.3	-0.7	-0.4	-2.0	-0.7	-1.4	-0.6
Qualifications: College or University degree	0.1	0.4	1.3	-1.1	-0.8	0.6	-0.3	1.0	-0.5	-0.5	-0.5	-0.8	-1.0	-0.3	0.3	-0.3	0.7	0.4
Eye problems/disorders: None of the above	1.7	1.9	4.7	1.5	2.0	-2.0	0.3	-2.2	-0.5	-0.4	-1.2	-1.8	-1.7	0.9	-0.1	0.1	-0.9	-2.1
Mouth/teeth dental problems: Loose teeth	1.4	1.7	5.7	-1.5	-1.9	1.8	-0.8	1.5	0.7	-1.4	-1.2	-0.1	-0.2	-2.4	-1.1	-1.3	-0.8	0.8
Emphysema/chronic bronchitis	2.0	2.3	4.5	-2.1	-0.1	0.0	-1.3	-0.4	-1.3	-1.6	-1.7	-2.1	-1.9	-1.6	-0.3	-2.1	-1.9	-1.2
Medication for pain relief, constipation, heartburn	1.1	1.8	4.1	0.2	-1.9	1.6	-1.1	2.0	0.2	1.3	1.2	0.9	1.1	0.5	1.6	0.6	1.8	1.9
Neck or shoulder pain in last month	0.7	0.9	3.1	-0.4	0.2	-0.5	1.1	-0.3	0.6	-0.7	-0.4	-1.4	-1.4	-1.3	-0.4	-1.8	-1.4	-0.9
Medication: Blood pressure	1.7	3.0	7.5	-0.9	-2.5	2.1	-1.7	2.5	1.3	-1.0	-1.7	-1.7	-1.2	-2.6	0.2	-2.7	-0.0	0.1
Angina (self-reported)	0.9	1.2	3.3	0.8	-1.8	1.6	0.1	1.8	1.6	0.5	0.4	0.8	0.1	-0.4	0.4	-0.1	1.5	1.6
Migraine (self-reported)	1.0	1.3	4.9	-1.1	-0.2	0.1	1.2	-0.1	0.3	-1.3	-0.8	-2.0	-2.2	-1.3	-0.4	-1.4	-0.8	-0.7
Medication: Ibuprofen	0.4	0.5	3.8	1.9	0.6	-0.8	-0.5	-0.5	0.6	0.1	0.2	0.2	0.4	0.3	-0.0	0.8	-0.1	-0.4
Medication: Allopurinol	0.5	0.6	1.7	1.2	-1.0	0.5	-0.5	1.0	-0.5	-0.6	-0.9	-0.2	-0.6	-1.3	-1.0	-0.7	0.1	0.8
Medication: Omeprazole	0.3	0.4	1.3	-0.6	-0.7	0.7	1.0	0.6	-1.1	0.4	0.2	-0.6	-0.8	-0.1	0.7	-0.2	0.6	-0.0
Medication: Seretide 50 evohaler	0.4	0.5	1.7	-0.3	0.2	-0.5	-1.3	-0.2	0.0	0.0	0.5	0.2	0.4	1.3	1.3	0.8	0.7	0.1
Mean time to correctly identify matches	0.5	0.9	4.0	-2.0	-0.7	1.2	1.2	0.6	0.4	-0.1	-1.0	-1.0	-1.1	-0.8	-0.1	-1.1	-0.1	0.0
Heart disease (mother)	0.9	1.1	4.1	-0.5	-0.6	0.5	1.6	0.5	0.2	2.0	1.5	1.2	0.7	1.0	1.1	0.5	1.1	1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	5.1	-0.9	-1.8	1.9	-0.8	1.6	-0.7	-0.3	0.6	0.2	0.5	0.8	2.3	0.1	1.5	1.1
Whole body fat mass	1.2	5.1	17.9	1.3	-2.6	4.2	0.3	3.0	2.1	2.6	2.9	2.0	1.8	-0.3	2.0	0.4	2.5	1.8
Leg fat mass (right)	0.9	3.5	9.2	1.3	-1.4	2.9	1.3	1.7	2.0	2.9	3.0	1.9	1.6	0.3	1.3	0.7	2.0	1.0
Arm predicted mass (right)	0.3	1.7	8.1	-1.1	-1.8	1.3	0.8	1.4	2.9	0.1	-0.0	-0.8	-0.8	-2.2	-0.1	-1.7	-0.1	0.0
Pulse rate, automated reading	1.5	4.9	15.0	0.9	3.6	-3.9	1.8	-3.7	-0.8	1.5	1.8	-0.4	-0.3	2.8	-0.5	1.9	-0.9	-2.8
Alcohol intake frequency.	0.2	0.4	2.2	-0.8	-0.4	0.6	-0.1	0.4	1.5	-0.5	-0.5	0.0	0.5	-0.5	0.3	-0.9	-0.0	0.0
Comparative height size at age 10	1.1	6.3	17.1	-1.6	-4.1	4.1	-2.3	3.6	1.4	-1.9	-2.5	-1.6	-1.1	-3.2	0.7	-3.2	0.9	1.3
Number of full sisters	0.3	0.3	1.7	1.3	-0.4	0.6	0.9	0.5	0.2	-0.1	0.6	0.6	0.4	-0.1	0.1	-0.3	0.5	0.4
Suffer from ‘nerves’	1.0	1.5	4.2	-0.8	-0.3	-0.0	-0.8	0.3	-1.4	-2.0	-1.9	-1.6	-1.1	-1.7	-1.2	-1.3	-1.1	-0.4
Overall health rating	0.3	0.6	1.7	-0.8	0.3	0.3	0.7	-0.3	0.8	-1.1	-1.0	-0.8	-1.0	-0.8	-0.6	-1.3	-0.5	0.3
Chest pain or discomfort	0.2	0.3	1.6	0.1	0.5	0.6	1.0	-0.3	-0.2	0.3	-0.2	-0.0	-0.8	0.2	0.5	-0.4	0.4	1.2
Had major operations	0.2	0.2	1.3	0.1	-0.0	0.1	-1.2	-0.0	1.1	-0.4	-0.5	0.3	0.1	-0.0	-0.3	-0.3	0.0	0.1
Age at last live birth	1.7	2.5	6.7	1.8	1.6	-1.8	2.0	-1.4	-0.3	1.1	2.6	0.8	0.5	2.4	1.4	2.1	0.5	-0.5
Family relationship satisfaction	1.5	1.9	4.2	1.8	-1.2	0.5	-0.3	1.0	1.4	1.0	1.7	1.4	0.8	1.3	1.9	1.0	2.0	1.9
Leg pain on walking	0.6	0.7	2.5	1.6	0.4	-0.5	0.5	-0.3	-1.4	0.4	0.7	0.8	0.7	0.7	0.6	1.2	1.0	0.3
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	3.8	-1.0	1.9	-1.2	0.2	-1.7	0.3	0.1	-0.6	-0.5	-0.8	0.8	-0.3	-0.2	-1.0	-1.2
Commuting to job workplace: Car/motor vehicle	1.1	1.3	3.4	0.2	-1.7	1.8	-1.4	1.7	-0.1	-1.0	0.5	0.4	0.6	-0.4	1.4	0.1	1.5	1.4
Illness, injury, bereavement, stress in last 2 years	2.8	3.4	8.8	-1.9	-0.7	1.2	-1.4	0.8	-0.3	-2.4	-3.0	-1.8	-1.9	-2.9	-1.6	-2.8	-1.5	-0.2
Medication: Aspirin	1.8	2.3	5.4	-0.1	1.7	-1.4	0.5	-1.8	0.0	-0.8	-2.0	-1.9	-2.3	-0.5	-1.7	-1.5	-1.7	-2.1
Supplements: Vitamin C	0.3	0.3	1.0	-0.1	0.7	-0.2	-0.2	-0.8	-0.8	-0.5	-0.4	-0.4	-1.0	0.2	-0.2	-0.0	-0.4	-0.9
Knee pain experienced in last month	1.3	2.1	6.2	-0.6	-1.5	1.7	-0.6	1.4	-0.3	-1.8	-1.5	-1.4	-1.3	-2.5	-0.7	-2.5	-1.0	-0.0
Hypertension (Self-reported)	0.7	1.8	5.1	-1.2	-2.3	1.9	-0.6	2.2	0.9	0.3	-0.2	0.5	0.8	-0.7	1.7	-1.2	1.3	2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.9	2.2	7.6	-0.3	-0.9	0.8	0.3	0.6	-1.2	-0.7	-1.8	-2.8	-2.4	-2.2	-0.8	-2.1	-0.7	-1.4
Illnesses of father: Heart disease	1.6	2.3	5.8	-0.2	-2.4	1.7	0.8	2.0	0.8	-1.2	-1.5	-1.6	-1.7	-2.0	0.8	-2.4	0.3	0.5
Illnesses of siblings: Diabetes	0.7	0.9	2.5	1.6	-1.5	0.1	0.9	1.2	0.1	0.6	1.1	0.1	0.2	-0.1	1.4	-0.1	1.2	0.9
Smoking status: Previous	0.6	1.0	4.7	-0.9	1.2	-0.8	0.2	-1.3	-2.2	-1.5	-0.6	-0.7	-0.5	0.2	-0.1	-0.6	-1.0	-0.7
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.1	6.6	-1.1	-2.6	2.3	-1.1	2.5	2.0	-0.3	0.2	0.4	0.6	-0.6	1.2	-0.5	1.0	1.6
Whole body fat-free mass	0.6	3.2	9.9	-1.2	-3.1	3.0	0.1	2.8	2.2	-0.2	-0.4	-0.4	-0.4	-2.8	0.4	-2.2	0.4	1.1
Leg fat-free mass (right)	0.8	4.4	15.4	-0.1	-3.8	3.9	-0.6	3.7	2.2	0.5	0.4	0.4	0.4	-2.5	1.1	-1.7	1.5	1.9
Arm fat percentage (left)	1.3	5.2	14.0	1.8	-2.1	3.7	0.6	2.6	1.2	3.1	3.4	2.5	2.1	0.4	2.2	1.1	2.6	1.7
Average weekly red wine intake	0.6	0.9	2.3	-1.5	1.3	-0.4	0.4	-1.4	0.1	-1.0	-1.4	-1.1	-0.9	-0.4	-0.5	-0.6	-1.0	-0.2
Handedness (chirality/laterality): Left-handed	1.7	2.1	5.4	-1.8	0.4	-0.4	-1.4	-0.5	0.1	-1.0	-1.2	-2.2	-2.1	-1.4	-1.1	-2.0	-1.3	-2.3
Mood swings	0.6	1.1	5.5	-0.9	-1.6	2.3	-0.2	1.6	0.1	0.1	0.5	0.0	-0.1	0.0	0.7	-0.9	1.0	1.4
Loneliness, isolation	0.3	0.5	2.1	-0.5	-0.9	1.4	-0.2	0.9	-0.1	0.8	-0.1	-0.0	0.4	-0.3	0.2	-0.4	0.6	1.4
Long-standing illness, disability or infirmity	0.2	0.4	1.6	0.3	-0.6	0.3	0.3	0.9	1.3	-0.7	0.1	-0.3	-0.8	-0.5	0.7	-0.7	0.3	0.4
Ever had bowel cancer screening	1.8	2.1	4.6	-0.5	1.5	-1.6	-0.8	-1.6	-0.7	-1.7	-2.2	-1.7	-1.6	-1.0	-2.0	-0.6	-1.7	-1.6
Diabetes diagnosed by doctor	1.3	2.2	7.0	-1.7	-2.6	1.5	-0.6	2.5	2.1	-0.9	-0.6	-0.5	-0.4	-2.0	0.1	-1.7	0.6	0.7
Ever had stillbirth, spontaneous miscarriage or termination	1.3	1.4	2.9	1.3	0.1	0.0	-1.5	0.2	1.7	0.7	0.8	1.2	1.2	1.3	1.2	1.6	1.6	1.2
Friendships satisfaction	1.2	1.4	5.0	0.9	-1.5	1.1	-0.1	1.1	-0.3	0.5	1.1	1.0	1.1	0.9	1.2	0.8	2.1	2.2
Qualifications: nursing, teaching	1.0	1.6	3.6	0.1	-1.2	1.3	-1.1	1.4	-0.0	0.7	1.6	1.3	1.9	0.3	1.2	0.8	1.6	1.9
Commuting to job workplace: Walk	0.7	0.7	2.3	0.4	0.8	-0.6	1.5	-0.7	-0.9	1.3	1.1	0.8	0.1	1.1	-0.0	0.9	-0.3	-0.6
Eye problems/disorders: Cataract	4.4	5.1	14.0	-0.2	-3.7	3.2	-0.8	3.7	1.9	0.7	1.6	2.4	2.1	-0.7	1.5	0.3	2.2	3.6
Mouth/teeth dental problems: Mouth ulcers	0.2	0.4	2.4	0.2	-0.6	0.4	-0.5	0.6	0.0	-1.6	-0.5	0.5	-0.3	-1.1	-0.2	-0.4	-0.3	0.5
Medication for cholesterol	0.5	0.7	2.7	1.2	0.2	0.1	0.5	-0.2	-0.9	1.3	1.6	0.9	0.3	0.6	-0.7	1.2	0.5	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	1.1	-0.2	0.8	-0.8	1.0	-0.7	1.0	0.2	0.5	0.3	0.1	0.1	-0.1	-0.0	-0.4	-0.1
Back pain experienced in last month	0.5	0.8	3.2	-0.6	-0.0	0.2	0.6	-0.0	1.0	-1.2	-1.8	-1.0	-0.7	-1.3	-0.4	-1.3	-0.6	-0.1
Mineral and other dietary supplements	0.4	0.5	2.2	-0.1	-1.1	1.5	0.0	1.1	0.1	0.7	0.4	0.3	1.0	-0.2	-0.3	-0.1	0.9	0.2
Breast cancer (self-reported)	0.4	0.5	1.7	-0.3	0.7	-0.9	-1.1	-0.7	1.3	0.5	0.4	0.3	0.2	0.6	0.9	0.3	0.2	0.4
Asthma (self-reported)	0.7	1.5	7.2	-2.7	-0.8	0.6	-1.1	0.5	-1.6	-1.3	-0.5	-1.6	-1.0	-0.6	1.1	-1.6	-0.3	0.2
Osteoporosis (self-reported)	0.9	1.1	10.7	1.0	0.4	-0.6	-0.6	-0.4	3.3	0.1	1.0	0.3	0.9	0.5	0.2	1.0	0.5	0.2
Osteoarthritis (self-reported)	0.2	0.3	1.4	-0.5	0.6	-0.4	1.2	-0.5	-0.4	-0.1	-0.4	-0.5	-0.7	0.1	-0.2	-0.6	-0.8	-0.3
Medication: Aspirin	1.3	1.7	4.5	-0.1	1.3	-1.1	0.3	-1.4	0.1	-0.6	-2.1	-1.7	-2.1	-0.4	-1.3	-1.4	-1.4	-1.7
Medication: Gliclazide	3.4	3.8	9.2	-2.7	-2.2	1.4	-1.1	2.0	-1.1	-2.3	-1.7	-2.1	-1.8	-3.0	-0.9	-2.9	-0.9	-0.6
Illnesses of father: None of the above (group 1)	0.7	0.8	2.4	0.6	1.5	-1.1	-1.5	-1.2	0.2	0.6	0.8	0.4	0.4	0.8	-0.6	1.3	-0.5	-0.6
Smoking status: Current	2.0	3.2	10.5	0.4	3.0	-3.0	2.3	-3.2	0.2	1.8	1.2	0.4	-0.1	2.1	-0.6	1.8	-0.8	-1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.3	3.8	0.8	1.6	-1.9	0.4	-1.6	-1.7	0.2	0.8	-0.4	0.0	1.7	0.6	0.6	-0.1	-1.5
Whole body water mass	0.5	3.0	9.2	-1.0	-3.0	2.8	0.1	2.7	2.5	-0.0	-0.2	-0.3	-0.3	-2.7	0.6	-2.0	0.5	1.1
Leg predicted mass (right)	0.8	4.2	14.9	-0.2	-3.7	3.9	-0.6	3.6	2.2	0.5	0.4	0.4	0.4	-2.5	1.1	-1.7	1.4	1.9
Arm fat mass (left)	1.1	4.7	15.6	1.0	-2.7	4.0	0.6	2.9	1.9	2.6	2.9	1.9	1.6	-0.3	2.0	0.2	2.4	1.6
Number of self-reported non-cancer illnesses	1.3	2.2	6.6	-2.0	-1.0	1.0	0.2	0.8	1.3	-1.9	-1.8	-1.9	-1.7	-1.9	-0.3	-2.6	-0.8	-0.2
Average weekly champagne plus white wine intake	0.2	0.3	0.9	0.1	0.9	-0.7	-0.3	-0.6	0.9	-0.3	-0.1	0.2	-0.0	-0.3	-0.9	0.2	-0.6	-0.5
Miserableness	0.5	0.9	2.4	-1.5	-0.9	1.5	-0.3	0.8	-1.2	-0.6	0.2	-1.0	-0.6	0.2	1.5	-0.8	0.6	0.6
Guilty feelings	1.9	2.9	9.7	0.5	-3.1	2.9	-1.0	3.1	-0.5	-0.4	-0.6	0.3	0.3	-0.6	1.5	-0.8	2.0	2.6
Wears glasses or contact lenses	0.5	0.6	1.8	-1.2	-0.7	0.6	-0.6	0.5	-0.8	-1.1	-1.4	-0.5	-0.2	-1.0	-0.4	-0.9	-0.2	-0.4
Ever taken oral contraceptive pill	1.4	1.6	4.8	1.5	1.1	-1.2	0.2	-0.9	-0.4	2.2	1.9	0.5	0.8	1.9	1.3	1.3	0.7	-0.4
Hearing aid user	0.8	0.9	2.9	1.0	-0.7	0.6	0.3	0.6	1.6	0.6	0.6	1.1	1.7	0.3	0.2	0.9	1.5	0.9
Mother’s age at death	0.3	0.4	1.2	0.2	-1.1	0.7	-0.9	0.9	-0.9	0.0	-0.2	0.7	0.7	-0.2	-0.1	0.2	0.2	1.0
Financial situation satisfaction	0.8	1.0	2.6	0.7	-0.5	0.5	0.6	0.4	1.6	1.0	1.5	1.1	0.8	1.1	0.8	0.9	1.1	1.3
Tinnitus: Yes, now most or all of the time	0.7	0.8	2.5	0.1	0.8	-1.2	-0.0	-0.9	-1.6	-1.4	-0.5	-0.8	-1.2	-0.4	-0.9	-0.1	-1.1	-0.6
Commuting to job workplace: Public transport	0.1	0.1	0.6	0.3	0.2	-0.4	-0.3	-0.2	0.4	0.8	-0.5	0.0	-0.1	0.2	-0.5	-0.1	-0.2	-0.3
Eye problems/disorders: Glaucoma	1.1	1.3	3.6	-1.9	0.3	0.2	-0.2	-0.2	-1.4	-0.6	-1.5	-1.7	-1.6	-0.9	-0.9	-1.1	-1.1	-1.3
Medication: Blood pressure	0.2	0.3	1.0	-0.8	-0.4	0.5	0.7	0.3	-0.2	0.5	-0.1	0.1	0.6	0.0	1.0	-0.4	0.7	0.9
Pain type(s) experienced in last month: Hip pain	0.8	1.0	3.5	-0.2	0.3	0.2	-1.7	-0.2	-0.4	-1.9	-1.2	-1.3	-1.1	-1.2	-0.3	-1.2	-1.1	-0.8
Supplements: Fish oil (including cod liver oil)	0.8	1.1	3.0	-1.1	1.4	-1.1	0.3	-1.4	-0.7	-0.5	-1.3	-0.8	-1.0	-0.3	-0.9	-0.5	-1.7	-1.0
High cholesterol (Self-reported)	2.4	4.2	11.7	-3.2	-1.9	2.0	-0.9	1.7	2.3	-1.9	-1.4	-2.3	-1.9	-2.9	0.1	-3.4	-1.3	-0.3
Medication: Bendroflumethiazide	0.3	0.5	1.0	-0.3	-0.9	0.9	-0.2	0.7	1.0	1.0	0.7	0.4	0.7	-0.3	0.8	-0.3	0.6	0.6
Medication: Paracetamol	1.0	1.5	6.1	1.5	-0.1	-0.3	1.2	-0.1	0.5	1.2	1.7	1.9	2.5	1.0	-0.1	1.6	1.1	0.6
Medication: Lisinopril	1.0	1.3	3.1	-0.5	-1.7	1.8	-1.1	1.3	-0.1	-0.5	-1.7	-1.1	-0.8	-1.4	0.1	-1.7	-0.1	1.0
Medication: Atorvastatin	0.8	1.0	3.7	-1.1	-0.6	0.7	1.0	0.6	1.4	-0.6	-0.8	-1.4	-1.4	-1.0	0.4	-1.9	-0.3	0.1
Illnesses of father: High blood pressure	1.3	1.6	4.0	-0.8	-1.9	1.7	1.2	2.0	1.3	-1.3	-0.6	0.1	-0.4	-1.1	0.4	-1.8	0.6	1.5
Alcohol drinker status: Never	0.6	0.7	2.9	-0.2	0.3	-0.3	-0.5	-0.3	0.3	-1.2	-0.4	-1.7	-1.3	-0.5	-0.2	-0.9	-0.8	-1.6
Ever smoked	1.4	2.5	10.4	-0.3	2.8	-2.7	1.5	-3.2	0.1	-0.3	-0.7	-0.9	-0.8	0.7	-1.5	0.3	-1.5	-1.5
Basal metabolic rate	0.6	3.3	11.2	-0.6	-3.2	3.4	0.3	3.0	2.4	0.6	0.5	0.2	0.2	-2.3	0.9	-1.6	1.1	1.4
Leg fat percentage (left)	0.6	2.1	8.6	1.4	0.3	1.5	1.8	0.1	1.3	2.8	2.9	1.2	0.9	1.1	0.9	1.0	1.1	-0.4
Arm fat-free mass (left)	0.4	2.1	6.9	-0.6	-2.5	2.2	0.6	2.2	2.6	0.9	0.6	-0.1	-0.1	-1.8	0.8	-1.4	0.8	0.9
Number of operations (self-reported)	0.7	1.0	4.4	0.2	-1.4	0.7	-1.3	1.1	0.7	-0.8	-0.7	1.2	1.1	-0.5	-0.1	-0.1	0.9	2.1
Average weekly beer plus cider intake	0.3	0.5	1.8	-0.4	0.5	-0.9	1.4	-0.7	0.8	0.4	1.0	-0.0	0.2	0.3	-0.6	0.1	-0.7	-0.9
Irritability	0.1	0.2	1.7	-0.4	0.2	0.2	1.3	-0.1	-0.5	0.5	0.2	0.1	-0.4	0.2	-0.5	-0.5	0.1	0.1
Risk taking	0.8	1.2	4.1	1.5	-0.5	0.3	-0.7	0.3	0.4	-0.1	0.4	1.5	2.0	1.3	0.9	1.4	1.4	1.1
Ever had prostate specific antigen (PSA) test	1.4	1.6	6.4	-0.1	0.8	-0.5	-1.9	-0.7	-0.2	-1.8	-2.5	-1.3	-1.6	-1.1	-1.2	-0.8	-1.0	-0.9
Fractured/broken bones in last 5 years	0.7	0.8	2.5	-0.1	-1.4	1.4	0.2	1.3	1.6	0.5	0.5	-0.0	0.0	0.2	1.3	-0.5	0.9	1.0
Age started oral contraceptive pill	1.2	1.5	5.9	-0.4	-0.3	-0.1	-0.4	0.1	-1.7	-0.8	-0.4	-2.4	-1.5	-1.3	0.0	-1.7	-1.0	-2.1
Diastolic blood pressure, automated reading	1.0	3.0	8.6	-1.7	-2.5	2.9	-0.7	2.3	-0.2	-1.4	-2.1	-0.8	-0.3	-2.6	-0.5	-2.4	-0.1	0.8
Ever depressed for a whole week	2.7	3.3	12.6	0.3	2.3	-1.6	0.3	-2.2	-1.3	1.8	1.4	2.0	1.8	3.5	1.1	2.8	1.2	0.9
Unable to work because of sickness or disability	1.3	1.7	5.2	-0.8	1.9	-1.8	2.1	-2.3	1.7	0.3	-0.0	-0.4	-0.8	0.5	-1.4	-0.4	-1.2	-0.4
Commuting to job workplace: Cycle	0.8	0.9	2.2	-1.0	1.5	-1.2	0.0	-1.3	-1.0	-0.8	-1.4	-0.7	-0.3	-0.2	-0.9	-0.2	-1.3	-0.9
Myopia	0.1	0.2	0.9	0.6	0.3	0.1	-0.9	-0.0	-0.1	0.3	-0.1	-0.1	-0.6	0.4	0.4	0.5	0.1	-0.4
Vascular/heart problems diagnosed by doctor	0.5	1.4	4.7	1.2	1.7	-1.6	0.5	-1.6	-1.0	-0.5	0.5	-0.9	-1.1	0.6	-1.1	0.9	-0.9	-2.2
Cholesterol lowering medication	0.5	0.8	2.8	-0.1	-0.4	0.2	0.2	0.4	1.2	1.0	0.8	1.0	1.1	1.0	1.7	0.6	1.1	0.7
Medication: Omeprazole (e.g. Zanprol)	0.4	0.4	1.9	-1.4	-0.7	0.9	0.1	0.5	-1.0	-0.4	-0.6	-0.7	-0.8	-0.3	0.4	-0.3	0.3	-0.1
Pain experienced in last month	1.1	1.8	3.4	-0.3	-0.7	0.7	0.1	0.9	1.0	1.5	1.7	1.7	1.6	1.5	1.6	1.8	1.7	1.2
Supplements: Calcium	2.1	2.4	6.0	2.0	0.5	-1.5	0.2	-0.4	2.0	1.2	1.8	1.9	1.1	2.0	1.5	2.5	1.3	1.1
Basal cell carcinoma (self-reported)	0.1	0.1	0.5	-0.0	0.3	-0.4	-0.7	-0.2	0.5	0.1	0.6	0.6	0.5	0.2	-0.1	0.4	-0.0	0.1
Heart attack/myocardial infarction (self-reported)	0.6	0.7	2.3	-0.0	0.7	-0.3	0.8	-0.6	-0.7	-1.5	-1.1	-1.0	-1.3	-0.6	-0.8	-1.0	-0.9	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.1	0.8	-0.7	1.1	0.5	0.8	-0.1	0.6	0.4	0.9	0.8	-0.3	0.2	0.1	0.8	0.8
Heart disease (siblings)	0.4	0.5	1.3	0.9	-1.1	0.7	0.5	1.0	0.4	0.8	1.1	-0.1	-0.0	-0.6	0.2	-0.3	0.7	0.5
Alcohol drinker status: Previous	0.7	0.9	2.4	-0.3	-0.1	0.5	-0.1	0.1	1.0	-1.5	-1.5	-0.2	0.1	-1.6	-1.5	-1.2	-0.8	0.4
Pack years of smoking	0.8	1.2	3.4	-0.1	-0.2	0.8	0.5	0.1	1.2	-0.3	-1.2	-1.5	-1.4	-1.7	-1.6	-1.8	-1.1	-0.6
Impedance of whole body	0.3	1.5	5.5	0.7	0.6	0.4	-1.2	-0.1	-0.9	0.9	1.1	1.3	1.2	2.2	1.0	2.3	1.5	0.7
Leg fat mass (left)	0.8	3.0	8.6	1.2	-1.4	2.9	1.1	1.7	2.1	2.6	2.8	1.5	1.3	0.1	1.2	0.4	1.8	0.8
Arm predicted mass (left)	0.3	1.7	6.9	-0.4	-2.2	2.0	0.6	1.9	2.6	0.8	0.7	-0.0	0.1	-1.6	0.8	-1.1	0.8	0.8