TWAS
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Usage
Models
Genes
Traits
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Traits
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Blood White Count
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chr3:19,382,787-20,893,060
Best TWAS P=3.06e-09 · Best GWAS P=9.28e-09 conditioned to 0.0119
19.4M
19.6M
19.8M
20M
20.2M
20.4M
20.6M
20.8M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
KAT2B
0.05
0.02
bslmm
462
0.02
2.7e-03
-5.7
-5.9
3.1e-09
0.64
0.01
0.98
TRUE
2
GTEx
Nerve Tibial
KAT2B
0.28
0.27
enet
9
0.29
1.8e-20
-5.5
-5.7
1.3e-08
0.75
0.02
0.98
FALSE
4
ROSMAP
Brain Pre-frontal Cortex
KAT2B
0.22
0.19
enet
21
0.29
7.0e-38
-3.7
-5.6
2.3e-08
0.69
0.99
0.00
FALSE
3
GTEx
Thyroid
KAT2B
0.13
0.18
lasso
3
0.17
5.5e-13
-5.5
-5.5
3.6e-08
0.79
0.04
0.96
FALSE
5
The Cancer Genome Atlas
Brain Lower Grade Glioma
KAT2B
0.06
0.04
blup
120
0.04
9.5e-06
-5.7
-5.3
1.2e-07
0.68
0.01
0.99
FALSE