Best TWAS P=5.2e-18 · Best GWAS P=2.56e-19 conditioned to 2.1e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | NEK10 | 0.04 | 0.03 | blup | 450 | 0.03 | 9.5e-05 | -4.0 | 5.5 | 5.1e-08 | -0.10 | 0.71 | 0.01 | TRUE |
2 | NTR | Blood | EOMES | 0.03 | 0.02 | lasso | 3 | 0.02 | 3.0e-08 | 8.7 | 8.7 | 5.2e-18 | 0.83 | 0.02 | 0.98 | TRUE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | EOMES | 0.11 | 0.10 | enet | 10 | 0.10 | 1.3e-10 | 6.5 | 6.5 | 9.8e-11 | 0.66 | 0.96 | 0.04 | FALSE |