Best TWAS P=1.67e-36 · Best GWAS P=2.29e-56 conditioned to 2.56e-19
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | OSCP1 | 0.04 | 0.04 | lasso | 2 | 0.03 | 1.6e-04 | -6.4 | 6.2 | 4.0e-10 | 0.32 | 0.89 | 0.00 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | MRPS15 | 0.14 | 0.03 | enet | 18 | 0.08 | 6.9e-07 | 5.4 | 6.7 | 2.2e-11 | 0.12 | 0.62 | 0.03 | TRUE |
| 3 | GTEx | Thyroid | OSCP1 | 0.14 | 0.09 | lasso | 4 | 0.10 | 4.3e-08 | -6.4 | -5.6 | 2.5e-08 | -0.33 | 0.99 | 0.00 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | OSCP1 | 0.04 | 0.02 | blup | 67 | 0.02 | 5.8e-03 | 10.0 | -12.6 | 1.7e-36 | -0.55 | 0.03 | 0.75 | TRUE |
| 5 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | OSCP1 | 0.05 | 0.02 | blup | 64 | 0.04 | 6.7e-04 | 10.0 | -7.8 | 8.4e-15 | -0.23 | 0.02 | 0.29 | FALSE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | LSM10 | 0.07 | 0.05 | blup | 44 | 0.04 | 3.4e-05 | 12.6 | 7.4 | 1.9e-13 | 0.35 | 0.09 | 0.46 | FALSE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | OSCP1 | 0.11 | 0.05 | blup | 67 | 0.07 | 2.1e-07 | -1.0 | -6.8 | 1.2e-11 | -0.16 | 0.77 | 0.01 | FALSE |