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chr3:51,616,334-53,860,103

Best TWAS P=5.14e-10 · Best GWAS P=1.36e-08 conditioned to 0.00981

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	NT5DC2	0.11	0.05	enet	22	0.04	5.0e-06	-5.5	5.3	9.2e-08	-0.63	0.00	0.99	FALSE
2	GTEx	Adipose Subcutaneous	TMEM110	0.12	0.05	lasso	6	0.03	7.3e-04	-5.7	5.9	4.2e-09	-0.96	0.00	0.99	FALSE
3	GTEx	Adipose Visceral Omentum	TMEM110	0.25	0.15	enet	18	0.20	7.3e-11	3.7	5.7	1.1e-08	-0.49	0.85	0.09	FALSE
4	GTEx	Adrenal Gland	RFT1	0.15	0.02	enet	11	0.03	4.0e-02	-4.6	-5.1	2.7e-07	0.20	0.16	0.28	FALSE
5	GTEx	Artery Aorta	PPM1M	0.14	0.04	enet	17	0.06	2.2e-04	-2.4	-5.2	2.4e-07	0.40	0.07	0.82	FALSE
6	GTEx	Artery Tibial	TMEM110	0.15	0.07	lasso	3	0.07	2.0e-06	3.8	5.7	1.4e-08	-0.69	0.06	0.93	FALSE
7	GTEx	Artery Tibial	RP5-966M1.6	0.07	0.07	lasso	4	0.08	1.4e-06	3.7	5.3	1.3e-07	-0.62	0.16	0.79	FALSE
8	GTEx	Colon Sigmoid	RP5-966M1.6	0.14	0.00	enet	17	0.02	9.1e-02	2.1	5.3	9.2e-08	-0.60	0.04	0.76	FALSE
9	GTEx	Esophagus Muscularis	ITIH4-AS1	0.07	0.05	lasso	3	0.07	4.7e-05	3.8	5.7	1.6e-08	-0.69	0.05	0.91	FALSE
10	GTEx	Nerve Tibial	TMEM110	0.13	0.06	lasso	3	0.10	1.4e-07	3.8	5.8	5.1e-09	-0.74	0.03	0.96	FALSE
11	GTEx	Prostate	RFT1	0.39	0.18	enet	17	0.24	1.1e-06	-4.4	-5.6	2.0e-08	0.50	0.25	0.56	FALSE
12	GTEx	Prostate	RP5-966M1.6	0.19	0.19	lasso	2	0.19	1.8e-05	3.5	5.3	1.5e-07	-0.61	0.05	0.72	FALSE
13	GTEx	Skin Not Sun Exposed Suprapubic	TMEM110	0.15	0.05	lasso	5	0.08	3.1e-05	-5.1	5.8	5.9e-09	-0.82	0.01	0.98	FALSE
14	GTEx	Stomach	RFT1	0.23	0.03	enet	19	0.06	6.3e-04	-4.4	-6.2	5.1e-10	0.57	0.25	0.47	TRUE
15	GTEx	Testis	ITIH4-AS1	0.23	0.13	enet	12	0.21	8.2e-10	-4.7	5.2	1.6e-07	-0.75	0.03	0.97	FALSE
16	GTEx	Thyroid	NISCH	0.08	0.04	enet	17	0.04	5.5e-04	-4.7	-5.9	3.9e-09	0.71	0.10	0.86	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	ITIH4	0.30	0.19	enet	22	0.27	9.0e-35	-5.7	5.8	8.9e-09	-0.83	0.00	1.00	FALSE
18	YFS	Blood	ITIH4	0.63	0.34	enet	95	0.50	2.9e-192	-5.1	5.5	4.3e-08	-0.66	0.04	0.96	FALSE
19	The Cancer Genome Atlas	Breast Invasive Carcinoma	RFT1	0.10	0.08	enet	11	0.15	2.3e-29	-4.8	-5.7	1.0e-08	0.54	0.01	0.97	FALSE
20	The Cancer Genome Atlas	Breast Invasive Carcinoma	TMEM110	0.13	0.09	lasso	3	0.10	5.9e-20	-4.2	-5.2	2.1e-07	0.94	0.02	0.98	FALSE
21	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	RFT1	0.14	0.08	enet	12	0.15	5.5e-08	-4.7	-5.7	1.2e-08	0.49	0.02	0.96	FALSE
22	The Cancer Genome Atlas	Colon Adenocarcinoma	RFT1	0.10	0.05	enet	12	0.05	1.0e-03	-4.7	-5.7	1.2e-08	0.56	0.01	0.79	FALSE
23	The Cancer Genome Atlas	Colon Adenocarcinoma	TMEM110	0.21	0.14	lasso	3	0.13	5.1e-08	-5.4	-5.2	1.9e-07	0.96	0.01	0.99	FALSE
24	The Cancer Genome Atlas	Glioblastoma Multiforme	RFT1	0.20	0.14	enet	11	0.09	8.8e-04	-4.5	-5.3	1.1e-07	0.38	0.02	0.77	FALSE
25	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	GLT8D1	0.21	0.02	enet	15	0.04	5.8e-05	-4.0	-5.4	5.6e-08	0.73	0.00	0.04	FALSE
26	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TMEM110	0.27	0.10	blup	59	0.14	3.0e-15	-4.9	-5.2	1.6e-07	0.90	0.05	0.94	FALSE
27	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	RFT1	0.15	0.21	lasso	8	0.22	1.4e-24	-4.6	-5.2	1.5e-07	0.30	0.03	0.94	FALSE
28	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	RFT1	0.24	0.12	lasso	5	0.20	1.3e-11	-4.8	-5.6	2.2e-08	0.52	0.01	0.97	FALSE
29	The Cancer Genome Atlas	Brain Lower Grade Glioma	RFT1	0.22	0.28	enet	13	0.31	2.5e-36	-4.4	-5.3	1.1e-07	0.37	0.04	0.91	FALSE
30	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	RFT1	0.31	0.07	blup	45	0.19	1.8e-09	-4.3	-5.4	7.8e-08	0.58	0.02	0.96	FALSE
31	The Cancer Genome Atlas	Lung Adenocarcinoma	RFT1	0.14	0.11	blup	45	0.11	1.9e-12	-4.8	-5.7	1.0e-08	0.61	0.01	0.98	FALSE
32	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	RFT1	0.07	0.03	enet	7	0.06	1.2e-07	-4.5	-5.8	7.6e-09	0.58	0.02	0.96	FALSE
33	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RFT1	0.21	0.10	lasso	6	0.23	1.9e-15	-4.7	-5.7	1.4e-08	0.52	0.02	0.96	FALSE
34	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	RFT1	0.41	0.17	enet	12	0.16	2.4e-07	-4.4	-5.4	6.3e-08	0.44	0.03	0.92	FALSE
35	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	RFT1	0.23	0.09	blup	45	0.08	3.8e-04	-4.7	-5.9	4.7e-09	0.41	0.02	0.86	FALSE
36	The Cancer Genome Atlas	Prostate Adenocarcinoma	RFT1	0.18	0.09	blup	45	0.09	4.8e-10	-4.7	-5.4	6.9e-08	0.66	0.01	0.98	FALSE
37	The Cancer Genome Atlas	Soft Tissue Sarcoma	RFT1	0.16	0.12	enet	16	0.14	1.7e-08	-4.7	-5.6	2.2e-08	0.58	0.01	0.97	FALSE
38	The Cancer Genome Atlas	Skin Cutaneous Melanoma	RFT1	0.29	0.04	blup	45	0.11	8.2e-04	-4.8	-5.2	1.6e-07	0.50	0.01	0.66	FALSE
39	The Cancer Genome Atlas	Stomach Adenocarcinoma	RFT1	0.13	0.05	blup	45	0.10	6.9e-08	-4.7	-5.6	2.5e-08	0.53	0.02	0.96	FALSE
40	The Cancer Genome Atlas	Testicular Germ Cell Tumors	RFT1	0.39	0.22	lasso	4	0.25	3.1e-09	-4.8	-5.1	2.9e-07	0.63	0.01	0.98	FALSE
41	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	RFT1	0.29	0.15	blup	45	0.15	6.5e-05	-4.5	-5.2	1.5e-07	0.51	0.01	0.74	FALSE