Best TWAS P=2.41e-09 · Best GWAS P=1.24e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | ST3GAL6-AS1 | 0.16 | 0.15 | lasso | 6 | 0.14 | 2.7e-11 | 5.7 | -6.0 | 2.7e-09 | -0.99 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Artery Aorta | ST3GAL6-AS1 | 0.32 | 0.22 | lasso | 9 | 0.25 | 5.7e-14 | 5.7 | -5.2 | 1.8e-07 | -0.90 | 0.00 | 1.00 | FALSE |
| 3 | GTEx | Artery Tibial | ST3GAL6-AS1 | 0.24 | 0.09 | lasso | 7 | 0.17 | 1.6e-13 | -4.2 | -5.7 | 1.2e-08 | -0.83 | 0.00 | 1.00 | FALSE |
| 4 | GTEx | Brain Caudate basal ganglia | ST3GAL6-AS1 | 0.20 | 0.22 | enet | 7 | 0.12 | 2.2e-04 | 5.7 | -5.5 | 2.9e-08 | -0.98 | 0.00 | 0.99 | FALSE |
| 5 | GTEx | Brain Cerebellum | ST3GAL6-AS1 | 0.37 | 0.31 | lasso | 4 | 0.30 | 1.5e-09 | 5.7 | -5.8 | 6.3e-09 | -0.99 | 0.00 | 1.00 | FALSE |
| 6 | GTEx | Brain Hypothalamus | ST3GAL6-AS1 | 0.62 | 0.30 | enet | 38 | 0.15 | 2.8e-04 | 5.7 | -6.0 | 2.7e-09 | -0.80 | 0.00 | 0.99 | FALSE |
| 7 | GTEx | Brain Putamen basal ganglia | ST3GAL6-AS1 | 0.22 | 0.24 | lasso | 3 | 0.02 | 1.2e-01 | 5.7 | -5.7 | 1.4e-08 | -1.00 | 0.00 | 0.98 | FALSE |
| 8 | GTEx | Breast Mammary Tissue (Female) | ST3GAL6-AS1 | 0.15 | 0.14 | lasso | 5 | 0.10 | 5.0e-04 | 5.6 | -5.8 | 6.1e-09 | -0.88 | 0.01 | 0.92 | FALSE |
| 9 | GTEx | Cells EBV-transformed lymphocytes | ST3GAL6-AS1 | 0.45 | 0.04 | enet | 2 | 0.04 | 2.0e-02 | 5.7 | -5.7 | 1.3e-08 | -1.00 | 0.01 | 0.88 | FALSE |
| 10 | GTEx | Esophagus Gastroesophageal Junction | ST3GAL6-AS1 | 0.28 | 0.13 | lasso | 6 | 0.17 | 1.1e-06 | -4.1 | -5.4 | 6.1e-08 | -0.90 | 0.01 | 0.99 | FALSE |
| 11 | GTEx | Esophagus Mucosa | ST3GAL6 | 0.21 | 0.14 | enet | 9 | 0.09 | 2.5e-06 | 5.7 | -5.3 | 1.2e-07 | -0.94 | 0.00 | 1.00 | FALSE |
| 12 | GTEx | Esophagus Mucosa | ST3GAL6-AS1 | 0.17 | 0.16 | lasso | 4 | 0.14 | 1.4e-09 | 5.7 | -5.7 | 1.2e-08 | -1.00 | 0.00 | 1.00 | FALSE |
| 13 | GTEx | Esophagus Muscularis | ST3GAL6-AS1 | 0.23 | 0.20 | lasso | 7 | 0.20 | 3.7e-12 | 5.7 | -5.9 | 4.7e-09 | -0.96 | 0.00 | 1.00 | FALSE |
| 14 | GTEx | Heart Atrial Appendage | ST3GAL6-AS1 | 0.55 | 0.38 | enet | 20 | 0.43 | 8.9e-21 | 5.7 | -5.4 | 7.3e-08 | -0.93 | 0.00 | 1.00 | FALSE |
| 15 | GTEx | Heart Left Ventricle | ST3GAL6-AS1 | 0.36 | 0.35 | lasso | 7 | 0.34 | 1.5e-18 | 5.7 | -5.8 | 8.2e-09 | -0.99 | 0.00 | 1.00 | FALSE |
| 16 | GTEx | Lung | ST3GAL6-AS1 | 0.11 | 0.11 | lasso | 2 | 0.10 | 2.1e-08 | 5.7 | -5.7 | 1.2e-08 | -1.00 | 0.00 | 1.00 | FALSE |
| 17 | GTEx | Muscle Skeletal | ST3GAL6-AS1 | 0.19 | 0.12 | lasso | 6 | 0.16 | 2.0e-15 | -3.9 | -5.2 | 2.0e-07 | -0.88 | 0.06 | 0.94 | FALSE |
| 18 | GTEx | Nerve Tibial | ST3GAL6-AS1 | 0.24 | 0.25 | lasso | 4 | 0.24 | 1.0e-16 | 5.7 | -5.8 | 7.3e-09 | -1.00 | 0.00 | 1.00 | FALSE |
| 19 | GTEx | Skin Not Sun Exposed Suprapubic | ST3GAL6-AS1 | 0.20 | 0.11 | lasso | 4 | 0.09 | 1.7e-05 | 5.7 | -5.7 | 1.4e-08 | -1.00 | 0.00 | 1.00 | FALSE |
| 20 | GTEx | Skin Sun Exposed Lower leg | ST3GAL6-AS1 | 0.18 | 0.15 | enet | 12 | 0.17 | 9.6e-14 | 5.7 | -5.8 | 8.0e-09 | -0.96 | 0.00 | 1.00 | FALSE |
| 21 | GTEx | Testis | ST3GAL6-AS1 | 0.13 | 0.20 | lasso | 2 | 0.18 | 1.9e-08 | 5.7 | -5.7 | 1.2e-08 | -1.00 | 0.00 | 1.00 | FALSE |
| 22 | GTEx | Thyroid | ST3GAL6-AS1 | 0.25 | 0.22 | lasso | 5 | 0.20 | 3.8e-15 | 5.7 | -6.0 | 2.4e-09 | -0.99 | 0.00 | 1.00 | TRUE |