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chr3:97,736,804-99,235,739

Best TWAS P=2.41e-09 · Best GWAS P=1.24e-08 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
22	GTEx	Thyroid	ST3GAL6-AS1	0.25	0.22	lasso	5	0.20	3.8e-15	5.7	-6.0	2.4e-09	-0.99	0.00	1.00	TRUE
1	GTEx	Adipose Subcutaneous	ST3GAL6-AS1	0.16	0.15	lasso	6	0.14	2.7e-11	5.7	-6.0	2.7e-09	-0.99	0.00	1.00	FALSE
6	GTEx	Brain Hypothalamus	ST3GAL6-AS1	0.62	0.30	enet	38	0.15	2.8e-04	5.7	-6.0	2.7e-09	-0.80	0.00	0.99	FALSE
13	GTEx	Esophagus Muscularis	ST3GAL6-AS1	0.23	0.20	lasso	7	0.20	3.7e-12	5.7	-5.9	4.7e-09	-0.96	0.00	1.00	FALSE
8	GTEx	Breast Mammary Tissue (Female)	ST3GAL6-AS1	0.15	0.14	lasso	5	0.10	5.0e-04	5.6	-5.8	6.1e-09	-0.88	0.01	0.92	FALSE
5	GTEx	Brain Cerebellum	ST3GAL6-AS1	0.37	0.31	lasso	4	0.30	1.5e-09	5.7	-5.8	6.3e-09	-0.99	0.00	1.00	FALSE
18	GTEx	Nerve Tibial	ST3GAL6-AS1	0.24	0.25	lasso	4	0.24	1.0e-16	5.7	-5.8	7.3e-09	-1.00	0.00	1.00	FALSE
20	GTEx	Skin Sun Exposed Lower leg	ST3GAL6-AS1	0.18	0.15	enet	12	0.17	9.6e-14	5.7	-5.8	8.0e-09	-0.96	0.00	1.00	FALSE
15	GTEx	Heart Left Ventricle	ST3GAL6-AS1	0.36	0.35	lasso	7	0.34	1.5e-18	5.7	-5.8	8.2e-09	-0.99	0.00	1.00	FALSE
3	GTEx	Artery Tibial	ST3GAL6-AS1	0.24	0.09	lasso	7	0.17	1.6e-13	-4.2	-5.7	1.2e-08	-0.83	0.00	1.00	FALSE
12	GTEx	Esophagus Mucosa	ST3GAL6-AS1	0.17	0.16	lasso	4	0.14	1.4e-09	5.7	-5.7	1.2e-08	-1.00	0.00	1.00	FALSE
16	GTEx	Lung	ST3GAL6-AS1	0.11	0.11	lasso	2	0.10	2.1e-08	5.7	-5.7	1.2e-08	-1.00	0.00	1.00	FALSE
21	GTEx	Testis	ST3GAL6-AS1	0.13	0.20	lasso	2	0.18	1.9e-08	5.7	-5.7	1.2e-08	-1.00	0.00	1.00	FALSE
9	GTEx	Cells EBV-transformed lymphocytes	ST3GAL6-AS1	0.45	0.04	enet	2	0.04	2.0e-02	5.7	-5.7	1.3e-08	-1.00	0.01	0.88	FALSE
7	GTEx	Brain Putamen basal ganglia	ST3GAL6-AS1	0.22	0.24	lasso	3	0.02	1.2e-01	5.7	-5.7	1.4e-08	-1.00	0.00	0.98	FALSE
19	GTEx	Skin Not Sun Exposed Suprapubic	ST3GAL6-AS1	0.20	0.11	lasso	4	0.09	1.7e-05	5.7	-5.7	1.4e-08	-1.00	0.00	1.00	FALSE
4	GTEx	Brain Caudate basal ganglia	ST3GAL6-AS1	0.20	0.22	enet	7	0.12	2.2e-04	5.7	-5.5	2.9e-08	-0.98	0.00	0.99	FALSE
10	GTEx	Esophagus Gastroesophageal Junction	ST3GAL6-AS1	0.28	0.13	lasso	6	0.17	1.1e-06	-4.1	-5.4	6.1e-08	-0.90	0.01	0.99	FALSE
14	GTEx	Heart Atrial Appendage	ST3GAL6-AS1	0.55	0.38	enet	20	0.43	8.9e-21	5.7	-5.4	7.3e-08	-0.93	0.00	1.00	FALSE
11	GTEx	Esophagus Mucosa	ST3GAL6	0.21	0.14	enet	9	0.09	2.5e-06	5.7	-5.3	1.2e-07	-0.94	0.00	1.00	FALSE
2	GTEx	Artery Aorta	ST3GAL6-AS1	0.32	0.22	lasso	9	0.25	5.7e-14	5.7	-5.2	1.8e-07	-0.90	0.00	1.00	FALSE
17	GTEx	Muscle Skeletal	ST3GAL6-AS1	0.19	0.12	lasso	6	0.16	2.0e-15	-3.9	-5.2	2.0e-07	-0.88	0.06	0.94	FALSE