[Hub]/) : Traits : Blood White Count : ← →

chr3:118,316,719-120,486,383

Best TWAS P=3.14e-12 · Best GWAS P=3.92e-12 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Artery Aorta	GSK3B	0.09	0.11	lasso	8	0.09	1.7e-05	-6.6	-7.0	3.1e-12	0.97	0.03	0.97	TRUE
10	NTR	Blood	ARHGAP31	0.03	0.01	enet	26	0.02	1.9e-06	-4.9	5.9	4.2e-09	0.00	0.54	0.01	TRUE
13	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GSK3B	0.04	0.05	lasso	3	0.04	2.4e-05	-6.5	-6.7	1.6e-11	0.97	0.02	0.97	FALSE
5	GTEx	Cells Transformed fibroblasts	GSK3B	0.06	0.07	lasso	3	0.05	2.2e-04	-6.7	-6.7	2.2e-11	0.97	0.02	0.97	FALSE
15	The Cancer Genome Atlas	Thyroid Carcinoma	GSK3B	0.07	0.07	blup	145	0.05	9.5e-06	-6.6	-6.7	2.3e-11	0.93	0.03	0.97	FALSE
9	GTEx	Nerve Tibial	GSK3B	0.19	0.12	lasso	5	0.10	2.0e-07	-6.5	-6.6	3.7e-11	0.95	0.04	0.96	FALSE
12	The Cancer Genome Atlas	Colon Adenocarcinoma	NR1I2	0.10	0.06	blup	67	0.05	6.9e-04	-5.6	6.5	5.7e-11	-0.51	0.05	0.39	FALSE
4	GTEx	Breast Mammary Tissue (Female)	GSK3B	0.05	-0.01	lasso	11	0.00	2.8e-01	-6.5	-6.5	6.0e-11	0.97	0.04	0.46	FALSE
3	GTEx	Artery Tibial	GSK3B	0.19	0.08	enet	41	0.18	2.5e-14	3.6	-6.4	1.3e-10	0.70	0.03	0.97	FALSE
1	GTEx	Adipose Subcutaneous	GSK3B	0.15	0.09	lasso	5	0.07	1.4e-06	-6.5	-6.3	2.4e-10	0.95	0.03	0.97	FALSE
7	GTEx	Esophagus Muscularis	GSK3B	0.13	0.06	enet	18	0.08	1.3e-05	-6.5	-6.3	2.9e-10	0.84	0.03	0.97	FALSE
11	ROSMAP	Brain Pre-frontal Cortex	GSK3B	0.17	0.16	bslmm	598	0.17	6.7e-21	-5.4	-5.8	6.1e-09	0.51	0.96	0.04	FALSE
6	GTEx	Esophagus Mucosa	GSK3B	0.14	0.05	lasso	5	0.08	8.5e-06	-5.4	-5.6	2.6e-08	0.75	0.08	0.91	FALSE
8	GTEx	Muscle Skeletal	GSK3B	0.10	0.04	lasso	8	0.07	1.3e-07	2.5	-5.2	1.8e-07	0.49	0.69	0.24	FALSE
14	The Cancer Genome Atlas	Prostate Adenocarcinoma	GSK3B	0.03	0.02	lasso	4	0.02	1.1e-03	4.5	-5.2	2.0e-07	0.54	0.05	0.61	FALSE