[Hub]/) : Traits : Blood White Count :

chr3:118,316,719-120,486,383

Best TWAS P=3.14e-12 · Best GWAS P=3.92e-12 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous GSK3B 0.15 0.09 lasso 5 0.07 1.4e-06 -6.5 -6.3 2.4e-10 0.95 0.03 0.97 FALSE
2 GTEx Artery Aorta GSK3B 0.09 0.11 lasso 8 0.09 1.7e-05 -6.6 -7.0 3.1e-12 0.97 0.03 0.97 TRUE
3 GTEx Artery Tibial GSK3B 0.19 0.08 enet 41 0.18 2.5e-14 3.6 -6.4 1.3e-10 0.70 0.03 0.97 FALSE
4 GTEx Breast Mammary Tissue (Female) GSK3B 0.05 -0.01 lasso 11 0.00 2.8e-01 -6.5 -6.5 6.0e-11 0.97 0.04 0.46 FALSE
5 GTEx Cells Transformed fibroblasts GSK3B 0.06 0.07 lasso 3 0.05 2.2e-04 -6.7 -6.7 2.2e-11 0.97 0.02 0.97 FALSE
6 GTEx Esophagus Mucosa GSK3B 0.14 0.05 lasso 5 0.08 8.5e-06 -5.4 -5.6 2.6e-08 0.75 0.08 0.91 FALSE
7 GTEx Esophagus Muscularis GSK3B 0.13 0.06 enet 18 0.08 1.3e-05 -6.5 -6.3 2.9e-10 0.84 0.03 0.97 FALSE
8 GTEx Muscle Skeletal GSK3B 0.10 0.04 lasso 8 0.07 1.3e-07 2.5 -5.2 1.8e-07 0.49 0.69 0.24 FALSE
9 GTEx Nerve Tibial GSK3B 0.19 0.12 lasso 5 0.10 2.0e-07 -6.5 -6.6 3.7e-11 0.95 0.04 0.96 FALSE
10 NTR Blood ARHGAP31 0.03 0.01 enet 26 0.02 1.9e-06 -4.9 5.9 4.2e-09 0.00 0.54 0.01 TRUE
11 ROSMAP Brain Pre-frontal Cortex GSK3B 0.17 0.16 bslmm 598 0.17 6.7e-21 -5.4 -5.8 6.1e-09 0.51 0.96 0.04 FALSE
12 The Cancer Genome Atlas Colon Adenocarcinoma NR1I2 0.10 0.06 blup 67 0.05 6.9e-04 -5.6 6.5 5.7e-11 -0.51 0.05 0.39 FALSE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma GSK3B 0.04 0.05 lasso 3 0.04 2.4e-05 -6.5 -6.7 1.6e-11 0.97 0.02 0.97 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma GSK3B 0.03 0.02 lasso 4 0.02 1.1e-03 4.5 -5.2 2.0e-07 0.54 0.05 0.61 FALSE
15 The Cancer Genome Atlas Thyroid Carcinoma GSK3B 0.07 0.07 blup 145 0.05 9.5e-06 -6.6 -6.7 2.3e-11 0.93 0.03 0.97 FALSE