Best TWAS P=7.23e-18 · Best GWAS P=1.06e-14 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Spleen | P2RY13 | 0.33 | 0.09 | lasso | 5 | 0.00 | 2.4e-01 | -7.3 | 7.6 | 3.9e-14 | -0.86 | 0.05 | 0.63 | FALSE |
| 2 | NTR | Blood | P2RY13 | 0.05 | 0.03 | blup | 499 | 0.04 | 2.3e-13 | -6.7 | -6.8 | 8.8e-12 | 0.75 | 0.05 | 0.95 | FALSE |
| 3 | YFS | Blood | P2RY13 | 0.13 | 0.15 | enet | 27 | 0.16 | 3.7e-50 | -7.7 | -8.6 | 7.2e-18 | 0.96 | 0.01 | 0.99 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | GPR87 | 0.09 | 0.11 | blup | 75 | 0.11 | 1.8e-10 | 3.5 | -5.4 | 6.6e-08 | 0.65 | 1.00 | 0.00 | FALSE |