TWAS
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About
Usage
Models
Genes
Traits
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Traits
:
Blood White Count
:
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chr3:150,346,654-151,744,900
Best TWAS P=7.23e-18 · Best GWAS P=1.06e-14 conditioned to 1
150.4M
150.6M
150.8M
151M
151.2M
151.4M
151.6M
151.8M
0
5
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
YFS
Blood
P2RY13
0.13
0.15
enet
27
0.16
3.7e-50
-7.7
-8.6
7.2e-18
0.96
0.01
0.99
TRUE
1
GTEx
Spleen
P2RY13
0.33
0.09
lasso
5
0.00
2.4e-01
-7.3
7.6
3.9e-14
-0.86
0.05
0.63
FALSE
2
NTR
Blood
P2RY13
0.05
0.03
blup
499
0.04
2.3e-13
-6.7
-6.8
8.8e-12
0.75
0.05
0.95
FALSE
4
The Cancer Genome Atlas
Thyroid Carcinoma
GPR87
0.09
0.11
blup
75
0.11
1.8e-10
3.5
-5.4
6.6e-08
0.65
1.00
0.00
FALSE