Best TWAS P=6.36e-11 · Best GWAS P=1.54e-07 conditioned to 0.205
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | DCAF16 | 0.10 | 0.01 | enet | 6 | 0.02 | 4.7e-02 | 4.8 | -6.1 | 1.2e-09 | -0.69 | 0.08 | 0.67 | FALSE |
| 2 | GTEx | Artery Tibial | DCAF16 | 0.16 | 0.16 | lasso | 5 | 0.13 | 1.5e-10 | -4.8 | -5.3 | 1.4e-07 | -0.31 | 0.10 | 0.90 | FALSE |
| 3 | GTEx | Breast Mammary Tissue (Male) | DCAF16 | 0.24 | 0.03 | enet | 18 | -0.01 | 4.4e-01 | 3.6 | -5.5 | 3.8e-08 | -0.69 | 0.04 | 0.56 | FALSE |
| 4 | GTEx | Esophagus Mucosa | DCAF16 | 0.10 | 0.02 | lasso | 4 | 0.02 | 8.3e-03 | -4.8 | -5.5 | 3.2e-08 | -0.32 | 0.07 | 0.68 | FALSE |
| 5 | GTEx | Spleen | DCAF16 | 0.35 | 0.02 | lasso | 5 | 0.11 | 8.5e-04 | -4.6 | -6.5 | 6.4e-11 | -0.66 | 0.04 | 0.64 | TRUE |
| 6 | GTEx | Stomach | DCAF16 | 0.21 | 0.04 | lasso | 6 | 0.02 | 5.6e-02 | -5.0 | -5.5 | 3.6e-08 | -0.23 | 0.04 | 0.78 | FALSE |
| 7 | GTEx | Thyroid | DCAF16 | 0.11 | 0.02 | lasso | 5 | 0.03 | 2.3e-03 | -4.6 | -6.1 | 1.1e-09 | -0.53 | 0.06 | 0.89 | FALSE |
| 8 | The Cancer Genome Atlas | Brain Lower Grade Glioma | DCAF16 | 0.09 | 0.02 | lasso | 3 | 0.04 | 5.2e-05 | -4.8 | -5.4 | 5.3e-08 | -0.55 | 0.01 | 0.96 | FALSE |
| 9 | The Cancer Genome Atlas | Prostate Adenocarcinoma | DCAF16 | 0.04 | 0.04 | blup | 31 | 0.04 | 2.2e-05 | -4.6 | -5.4 | 6.2e-08 | -0.60 | 0.01 | 0.95 | FALSE |
| 10 | The Cancer Genome Atlas | Thyroid Carcinoma | DCAF16 | 0.07 | 0.04 | blup | 31 | 0.07 | 4.9e-07 | -5.0 | -5.8 | 7.2e-09 | -0.55 | 0.01 | 0.98 | FALSE |