Best TWAS P=4.04e-13 · Best GWAS P=2.85e-15 conditioned to 1.6e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | TBC1D14 | 0.05 | 0.03 | lasso | 7 | 0.02 | 7.5e-08 | -7.4 | 7.2 | 4.0e-13 | -0.62 | 0.04 | 0.96 | TRUE |
| 2 | YFS | Blood | TBC1D14 | 0.20 | 0.18 | bslmm | 650 | 0.19 | 2.6e-60 | -7.4 | 6.7 | 2.1e-11 | -0.47 | 0.04 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | TBC1D14 | 0.06 | 0.04 | lasso | 2 | 0.05 | 7.6e-06 | -4.5 | 6.9 | 6.3e-12 | -0.77 | 0.09 | 0.86 | FALSE |