[Hub]/) : Traits : Blood White Count : ← →

chr4:37,915,462-39,824,758

Best TWAS P=4.45e-20 · Best GWAS P=1.76e-19 conditioned to 0.000908

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Aorta	RP11-617D20.1	0.27	0.18	lasso	6	0.24	1.6e-13	-2.5	-5.7	1.3e-08	0.14	0.19	0.81	FALSE
2	GTEx	Artery Tibial	RP11-617D20.1	0.32	0.23	enet	39	0.28	5.0e-22	-2.5	-7.2	5.1e-13	0.14	0.50	0.50	FALSE
3	GTEx	Brain Cerebellar Hemisphere	AC021860.1	0.50	0.30	lasso	6	0.34	1.7e-09	-8.8	-6.9	5.7e-12	0.42	0.04	0.92	FALSE
4	GTEx	Brain Cerebellar Hemisphere	RP11-617D20.1	0.53	0.25	lasso	8	0.32	5.1e-09	-8.8	-6.0	1.5e-09	0.45	0.04	0.81	FALSE
5	GTEx	Brain Cerebellum	AC021860.1	0.63	0.33	lasso	16	0.43	5.7e-14	-8.8	-7.7	9.9e-15	0.40	0.03	0.96	FALSE
6	GTEx	Brain Cerebellum	RP11-617D20.1	0.59	0.23	lasso	8	0.39	1.0e-12	-8.8	-6.5	7.0e-11	0.26	0.11	0.89	FALSE
7	GTEx	Brain Frontal Cortex BA9	RP11-617D20.1	0.34	0.14	lasso	4	0.14	1.7e-04	-8.8	-6.4	1.6e-10	0.48	0.08	0.62	FALSE
8	GTEx	Brain Hippocampus	AC021860.1	0.46	0.17	enet	35	0.19	2.8e-05	1.6	-5.4	6.6e-08	0.42	0.11	0.53	FALSE
9	GTEx	Brain Nucleus accumbens basal ganglia	AC021860.1	0.37	0.05	enet	20	0.12	5.2e-04	1.6	-7.2	8.4e-13	0.27	0.16	0.40	FALSE
10	GTEx	Brain Nucleus accumbens basal ganglia	RP11-617D20.1	0.65	0.14	lasso	14	0.27	7.6e-08	-8.8	-7.7	1.8e-14	0.36	0.09	0.76	FALSE
11	GTEx	Breast Mammary Tissue (Female)	FAM114A1	0.07	-0.01	lasso	4	0.01	1.7e-01	-4.5	-6.0	2.7e-09	0.34	0.05	0.09	FALSE
12	GTEx	Esophagus Muscularis	KLHL5	0.11	0.04	lasso	7	0.01	5.2e-02	4.7	5.8	8.2e-09	-0.08	0.34	0.12	TRUE
13	GTEx	Heart Atrial Appendage	RP11-617D20.1	0.29	0.14	lasso	6	0.17	3.7e-08	-2.5	-5.7	1.5e-08	0.14	0.14	0.86	FALSE
14	GTEx	Heart Left Ventricle	AC021860.1	0.26	0.15	lasso	5	0.19	1.4e-10	-8.8	-6.9	5.5e-12	0.28	0.04	0.96	FALSE
15	GTEx	Muscle Skeletal	AC021860.1	0.16	0.10	lasso	7	0.13	1.1e-12	-8.8	-6.1	9.0e-10	0.27	0.04	0.96	FALSE
16	GTEx	Pancreas	AC021860.1	0.41	0.33	lasso	6	0.44	5.0e-20	-8.8	-6.4	1.2e-10	0.36	0.02	0.98	FALSE
17	GTEx	Pancreas	RP11-617D20.1	0.34	0.27	lasso	6	0.33	1.8e-14	-8.8	-6.5	5.9e-11	0.24	0.05	0.95	FALSE
18	GTEx	Prostate	AC021860.1	0.28	0.15	enet	29	0.28	8.1e-08	-8.8	-6.3	3.4e-10	0.29	0.09	0.66	FALSE
19	GTEx	Skin Sun Exposed Lower leg	RP11-617D20.1	0.20	0.10	lasso	4	0.11	3.2e-09	-2.5	-5.2	2.5e-07	0.03	0.72	0.28	FALSE
20	GTEx	Testis	RP11-617D20.1	0.28	0.16	lasso	5	0.18	1.9e-08	-2.4	-5.3	1.1e-07	0.05	0.25	0.74	FALSE
21	GTEx	Vagina	RP11-617D20.1	0.31	0.01	lasso	8	0.02	1.4e-01	-2.5	-6.1	1.0e-09	0.15	0.07	0.16	FALSE
22	GTEx	Whole Blood	RP11-617D20.1	0.14	0.06	lasso	3	0.05	4.2e-05	7.7	-7.1	1.7e-12	0.33	0.30	0.61	FALSE
23	NTR	Blood	KLHL5	0.06	0.01	enet	26	0.04	3.1e-12	4.0	-5.8	8.2e-09	0.26	0.28	0.70	FALSE
24	The Cancer Genome Atlas	Esophageal Carcinoma	FLJ13197	0.16	0.04	lasso	2	0.02	8.9e-02	-8.8	-8.8	2.1e-18	0.59	0.02	0.31	FALSE
25	The Cancer Genome Atlas	Brain Lower Grade Glioma	FLJ13197	0.06	0.04	enet	9	0.06	1.3e-07	-8.8	-5.6	1.9e-08	0.28	0.03	0.97	FALSE
26	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	FLJ13197	0.06	0.00	blup	81	0.01	3.4e-02	-2.5	-6.1	8.7e-10	0.24	0.04	0.22	FALSE
27	The Cancer Genome Atlas	Testicular Germ Cell Tumors	FLJ13197	0.22	0.05	blup	85	0.10	2.4e-04	6.6	-9.2	4.5e-20	0.66	0.03	0.39	TRUE
28	The Cancer Genome Atlas	Thyroid Carcinoma	FLJ13197	0.16	0.08	blup	82	0.13	7.1e-13	-8.8	-5.3	8.8e-08	0.34	0.03	0.97	FALSE