TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Blood White Count
:
←
→
chr4:73,245,191-75,146,143
Best TWAS P=1.88e-49 · Best GWAS P=4.21e-170 conditioned to 7.4e-143
73.5M
74M
74.5M
75M
0
50
100
150
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
CXCL6
0.05
0.03
lasso
4
0.02
0.0031
14.8
14.8
1.9e-49
0.02
0.01
0.67
TRUE
4
The Cancer Genome Atlas
Prostate Adenocarcinoma
CXCL6
0.07
0.01
blup
40
0.02
0.0036
18.4
12.7
8.8e-37
0.02
0.00
0.82
TRUE
5
The Cancer Genome Atlas
Stomach Adenocarcinoma
CXCL6
0.04
0.02
blup
42
0.02
0.0072
3.5
11.5
1.7e-30
0.05
0.00
0.84
TRUE
2
The Cancer Genome Atlas
Esophageal Carcinoma
CXCL3
0.12
-0.01
blup
17
0.02
0.0864
3.2
8.3
7.7e-17
0.31
0.01
0.10
TRUE
1
YFS
Blood
ANKRD17
0.01
0.00
bslmm
348
0.00
0.0198
1.7
6.2
4.2e-10
-0.04
0.10
0.02
TRUE