Best TWAS P=1.88e-49 · Best GWAS P=4.21e-170 conditioned to 7.4e-143
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | YFS | Blood | ANKRD17 | 0.01 | 0.00 | bslmm | 348 | 0.00 | 0.0198 | 1.7 | 6.2 | 4.2e-10 | -0.04 | 0.10 | 0.02 | TRUE |
| 2 | The Cancer Genome Atlas | Esophageal Carcinoma | CXCL3 | 0.12 | -0.01 | blup | 17 | 0.02 | 0.0864 | 3.2 | 8.3 | 7.7e-17 | 0.31 | 0.01 | 0.10 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CXCL6 | 0.05 | 0.03 | lasso | 4 | 0.02 | 0.0031 | 14.8 | 14.8 | 1.9e-49 | 0.02 | 0.01 | 0.67 | TRUE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CXCL6 | 0.07 | 0.01 | blup | 40 | 0.02 | 0.0036 | 18.4 | 12.7 | 8.8e-37 | 0.02 | 0.00 | 0.82 | TRUE |
| 5 | The Cancer Genome Atlas | Stomach Adenocarcinoma | CXCL6 | 0.04 | 0.02 | blup | 42 | 0.02 | 0.0072 | 3.5 | 11.5 | 1.7e-30 | 0.05 | 0.00 | 0.84 | TRUE |