TWAS hub - CXCL6

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Kidney Renal Clear Cell Carcinoma	0.0526	0.0298	0.0069	0.028	0.016	0.005	NA	0.019	0.00036	0.0060	0.078	NA	0.0031
2	TCGA	Prostate Adenocarcinoma	0.0709	0.0351	0.0027	0.006	0.019	0.012	NA	0.011	0.06500	0.0036	0.017	NA	0.0210
3	TCGA	Stomach Adenocarcinoma	0.0390	0.0230	0.0099	0.016	0.024	0.008	NA	0.013	0.02200	0.0072	0.081	NA	0.0390

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Blood White Count	23.1	170.9	219.0	14.8	12.7	11.5
Medication: Gliclazide	5.0	5.7	6.6	2.6	2.2	2.4
Fasting Glucose	3.6	4.3	7.7	2.2	0.8	2.8
Mouth/teeth dental problems: Mouth ulcers	3.5	5.6	8.1	-2.8	-1.7	-2.4
Osteoarthritis (self-reported)	3.3	4.3	5.8	-2.4	-1.7	-2.0
Mean time to correctly identify matches	3.1	6.0	7.3	-2.6	-2.7	-2.0
Birth weight	3.0	6.5	17.5	1.4	0.3	4.2
Fractured/broken bones in last 5 years	2.9	3.7	8.1	1.7	2.8	-0.4
Medication: Blood pressure	2.8	5.3	10.9	-2.2	-0.3	-3.3
Reaction Time	2.7	5.2	5.8	-2.4	-2.1	-2.3
HbA1C	2.6	2.9	6.5	-2.5	-0.8	-1.3
Hair/balding pattern: Pattern 2	2.6	3.3	7.1	2.7	0.3	1.7
Average weekly spirits intake	2.4	2.9	4.8	1.9	2.2	0.7
Medication for pain relief, constipation, heartburn	2.3	4.0	6.9	1.0	2.6	2.0
Commuting to job workplace: Public transport	2.3	2.8	4.5	1.4	2.1	1.4
Mouth/teeth dental problems: Bleeding gums	2.1	2.7	4.7	-1.5	-1.1	-2.2
Health satisfaction	2.1	2.8	5.5	2.4	1.0	1.3
Illnesses of father: Heart disease	2.0	2.7	3.3	1.8	1.8	1.3
Breast cancer (self-reported)	2.0	2.3	2.9	1.7	1.2	1.7
Trunk fat-free mass	1.9	10.9	16.5	4.1	2.0	3.5
Trunk predicted mass	1.9	10.9	16.5	4.1	2.0	3.5
Wheeze or whistling in the chest in last year	1.9	3.5	9.2	0.1	-3.0	-1.1
Ever depressed for a whole week	1.9	2.3	3.7	1.9	1.7	-0.5
Tinnitus: Yes, but not now, but have in the past	1.8	2.0	4.7	0.4	2.2	1.0
Qualifications: A levels/AS levels or equivalent	1.8	4.0	5.0	2.2	-1.5	2.2
Forced expiratory volume in 1-second (FEV1), Best measure	1.8	5.8	7.5	1.5	2.7	2.7
Whole body fat-free mass	1.8	10.0	15.5	3.9	1.9	3.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.8	2.1	3.8	2.0	1.0	1.3
High blood pressure (mother)	1.7	2.4	3.0	1.7	1.5	1.3
Arm fat-free mass (right)	1.7	8.5	13.2	3.6	2.0	2.8
Whole body water mass	1.7	9.8	15.5	3.9	1.9	3.2
Verbal and Numeric Reasoning (VNR)	1.6	3.8	7.7	-1.7	-2.8	-0.8
Leg predicted mass (left)	1.6	8.3	13.3	3.6	1.7	3.0
Mouth/teeth dental problems	1.6	2.4	4.8	2.2	0.5	1.5
Migraine (self-reported)	1.6	2.0	4.0	-0.6	-2.0	1.3
Arm predicted mass (right)	1.6	8.1	13.2	3.6	1.8	2.8
Commuting to job workplace: Car/motor vehicle	1.6	1.9	2.9	0.6	-1.7	1.5
Basal metabolic rate	1.6	9.1	14.0	3.7	2.0	3.0
Severe depression (siblings)	1.5	1.7	3.4	1.8	0.7	1.1
Leg fat-free mass (left)	1.5	8.1	13.0	3.6	1.6	2.9
Vitamin and mineral supplements	1.4	1.9	2.7	-1.6	-1.1	-1.3
Forced expiratory volume in 1-second (FEV1)	1.4	4.6	6.7	1.2	2.4	2.6
Lung cancer (father)	1.4	1.6	3.1	1.3	1.8	-0.2
Arm fat-free mass (left)	1.4	6.9	10.3	3.2	2.1	2.4
Arm predicted mass (left)	1.4	6.9	10.8	3.3	2.0	2.4
Prostate Cancer	1.3	1.9	3.1	1.5	1.8	0.6
Lung FEV1/FVC ratio	1.3	6.6	9.4	2.8	1.6	3.1
Medication: Lansoprazole	1.3	1.5	2.7	-0.9	0.9	-1.6
Breastfed as a baby	1.3	1.6	2.4	-1.3	-0.9	-1.5
Leg fat-free mass (right)	1.3	6.9	11.4	3.4	1.5	2.7
Medication for cholesterol	1.3	2.0	3.2	1.7	0.1	1.8
Leg predicted mass (right)	1.3	6.8	11.2	3.4	1.5	2.7
Body Mass Index (BMI) (2010)	1.2	1.6	2.6	-0.7	-1.6	-1.3
Forced vital capacity (FVC), Best measure	1.2	4.5	6.7	1.2	2.3	2.6
Medication: Ibuprofen	1.2	1.5	3.2	-1.1	-1.8	-0.3
Commuting to job workplace: Walk	1.2	1.3	3.0	-0.8	-0.3	-1.7
Mean Putamen Volume	1.1	1.2	3.0	0.7	-1.7	-0.4
Ever unenthusiastic/disinterested for a whole week	1.1	1.4	3.8	1.9	0.6	0.2
Fluid intelligence score	1.1	2.3	6.0	-0.7	-2.4	-0.6
Illnesses of mother	1.1	1.3	3.4	-1.8	-0.1	-0.7
Blood clot in the leg (DVT)	1.1	1.4	1.6	-1.3	1.2	-1.1
Illnesses of father: None of the above (group 1)	1.1	1.3	2.0	-0.8	-1.4	1.1
Irritability	1.1	1.9	3.7	0.7	-1.9	-1.2
Sensitivity / hurt feelings	1.0	1.7	4.6	0.1	0.8	-2.1
Hearing difficulty/problems: Yes	1.0	1.6	3.8	0.6	0.7	-2.0
Townsend deprivation index at recruitment	1.0	1.3	2.4	-0.7	1.0	-1.6
Age when periods started (menarche)	1.0	2.4	5.0	1.4	2.2	0.5
Multivitamins +/- minerals	1.0	1.2	3.4	0.4	1.8	0.4
Weight	1.0	4.7	7.0	2.6	2.1	1.7
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.3	2.9	-1.0	-1.7	-0.1
Birth weight of first child	1.0	1.8	3.9	2.0	0.1	1.3
Ever highly irritable/argumentative for 2 days	1.0	1.1	2.9	-0.7	0.3	-1.7
Hypothyroidism/myxoedema (self-reported)	1.0	1.9	2.1	-1.4	-1.4	-1.3
Exposure to tobacco smoke outside home	1.0	1.4	2.0	-1.4	0.7	-1.2
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	2.5	1.6	1.1	0.0
Mineral and other dietary supplements	1.0	1.3	2.5	-1.1	-0.7	-1.6
Lupus	0.9	1.4	3.8	-0.4	-0.4	2.0
Primary Biliary Cirrhosis	0.9	1.3	3.7	0.0	-1.9	-0.5
Chronotype (morning person)	0.9	2.2	6.5	0.3	2.5	-0.1
Number of treatments/medications taken	0.9	1.6	3.9	0.6	-0.8	-2.0
Medication: Co-codamol	0.9	1.1	1.7	1.3	1.0	0.7
Taking other prescription medications	0.9	1.4	2.9	-0.5	-1.7	-1.1
Medication: Atenolol	0.9	1.2	3.1	-0.0	-0.7	-1.8
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.0	2.6	-0.4	-0.5	-1.6
Shortness of breath walking on level ground	0.9	1.0	1.7	1.3	1.0	-0.6
Chest pain or discomfort	0.9	1.2	2.0	-0.8	-1.4	-1.0
Tinnitus: Yes, now most or all of the time	0.9	1.1	2.1	-0.0	-1.5	-1.0
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	1.8	-0.1	-1.3	-1.4
Supplements: Calcium	0.9	1.0	2.6	0.5	0.5	1.6
Breast Cancer	0.8	1.9	5.1	-0.1	-2.3	-0.7
Neuroticism (2016)	0.8	1.1	1.9	1.1	1.4	0.5
Ulcerative Colitis	0.8	1.1	3.2	-0.3	-1.8	-0.0
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	1.8	0.1	1.3	-0.9
Hand grip strength (right)	0.8	2.3	4.3	1.4	0.6	2.1
Forced vital capacity (FVC)	0.8	3.0	4.7	0.9	1.9	2.2
Qualifications: None of the above	0.8	1.7	3.6	-1.1	0.6	-1.9
Allergy	0.8	1.7	3.6	0.8	1.9	1.0
Worry too long after embarrassment	0.8	1.3	3.1	0.7	1.8	-0.6
Age at first live birth	0.8	1.5	2.5	-1.2	-1.6	0.7
Comparative height size at age 10	0.8	4.4	7.2	1.9	1.5	2.7
Supplements: Vitamin C	0.8	1.0	2.3	1.5	-0.4	0.7
Guilty feelings	0.8	1.1	3.0	-0.6	-0.1	-1.7
Wears glasses or contact lenses	0.8	0.9	1.4	1.1	0.4	1.2
Hearing aid user	0.8	0.9	1.8	-0.6	1.3	-0.8
Deep venous thrombosis (DVT) (self-reported)	0.8	1.1	1.1	-1.0	1.1	-1.1
Alcohol drinker status: Previous	0.8	0.9	1.5	1.2	0.6	0.9
Ovarian Cancer	0.7	1.0	1.4	-1.0	-1.2	-0.7
Ever used hormone-replacement therapy (HRT)	0.7	0.9	1.4	-0.0	1.2	-1.1
Supplements: Zinc	0.7	0.7	1.2	0.4	-1.1	0.8
Diabetes (mother)	0.7	0.9	1.4	1.1	1.2	0.1
Serious illness, injury or assault to yourself	0.7	0.8	1.6	-0.0	-1.3	-0.9
High blood pressure	0.7	1.8	4.0	-1.2	-0.0	-2.0
Supplements: Glucosamine	0.7	0.9	2.1	-1.4	-0.5	-0.5
Medication: Levothyroxine sodium	0.7	1.2	2.2	-1.5	-0.8	-0.8
Chronic bronchitis/emphysema (father)	0.7	0.9	1.7	-0.8	-0.5	-1.3
Medication: Simvastatin	0.7	1.0	2.9	1.7	0.1	0.0
Worrier / anxious feelings	0.7	1.2	1.9	1.3	1.4	-0.2
Mouth/teeth dental problems: Dentures	0.7	1.3	2.8	-0.8	1.7	0.6
Standing height	0.7	7.2	11.4	2.6	1.9	3.4
Peak expiratory flow (PEF)	0.7	1.6	2.2	0.8	1.5	1.4
Medication: Paracetamol	0.7	1.1	3.1	-0.1	-1.8	-0.6
Medication: Amlodipine	0.7	1.0	1.5	0.2	1.2	-1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	2.5	1.6	-0.0	0.2
Emphysema/chronic bronchitis	0.7	0.8	1.9	-1.4	0.5	-0.6
Leg fat mass (right)	0.7	2.9	4.6	2.1	1.7	1.1
Number of full sisters	0.7	0.8	1.5	0.8	1.2	-0.6
Had major operations	0.7	0.8	2.2	-1.5	0.4	-0.1
Family relationship satisfaction	0.7	0.9	2.2	0.7	1.5	0.3
Leg pain on walking	0.7	0.8	1.7	0.8	1.3	-0.1
Knee pain experienced in last month	0.7	1.1	2.0	-1.4	-0.8	-0.9
Long-standing illness, disability or infirmity	0.7	1.1	1.8	1.0	-1.4	-0.6
Osteoporosis (self-reported)	0.7	0.8	1.5	1.2	1.0	0.1
Medication: Aspirin	0.7	1.0	1.7	0.4	-1.0	-1.3
Number of operations (self-reported)	0.7	1.0	1.5	-1.2	-0.9	-0.8
Ever had prostate specific antigen (PSA) test	0.7	0.8	2.0	0.0	0.6	1.4
Vascular/heart problems diagnosed by doctor	0.7	1.9	4.7	0.8	0.6	2.2
Leg fat mass (left)	0.7	2.7	4.2	2.1	1.7	1.0
Bipolar Disorder (2018)	0.6	0.9	2.3	-1.5	0.6	-0.2
Hypothyroidism (self reported)	0.6	1.4	1.8	-1.3	-1.3	-0.9
Neuroticism	0.6	1.4	4.2	0.1	0.4	-2.0
Medication: Metformin	0.6	0.9	1.5	-1.2	-0.8	-0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.7	1.3	1.1	-0.4	-0.9
Hayfever, allergic rhinitis or eczema	0.6	1.3	3.9	-0.3	-2.0	0.1
Alcohol usually taken with meals	0.6	1.0	1.6	-1.3	-0.8	-0.9
Had menopause	0.6	0.7	1.6	-0.5	-0.6	-1.3
Falls in the last year	0.6	0.9	1.9	1.4	0.5	-0.6
Noisy workplace	0.6	0.8	2.2	0.4	0.2	1.5
Number of full brothers	0.6	0.8	2.2	0.4	1.5	-0.1
Medication: Allopurinol	0.6	0.9	2.4	0.1	-1.6	0.4
Hypertension (Self-reported)	0.6	1.6	3.4	-1.0	0.5	-1.9
Number of self-reported non-cancer illnesses	0.6	1.0	1.7	0.5	-1.0	-1.3
Pain type(s) experienced in last month: Hip pain	0.6	0.7	2.0	0.2	-1.4	-0.4
High cholesterol (Self-reported)	0.6	1.0	3.0	1.7	0.2	0.2
Medication: Paracetamol	0.6	0.9	2.5	-0.1	-1.6	-0.5
Age started oral contraceptive pill	0.6	0.7	2.0	0.4	1.4	0.3
Heart attack/myocardial infarction (self-reported)	0.6	0.7	0.9	0.9	-0.7	-0.9
Schizophrenia vs Biploar Disorder	0.5	0.6	1.0	0.9	-1.0	0.1
Irritable Bowel Disease (IBD)	0.5	1.3	2.8	-1.7	-0.8	-0.6
LDL Cholesterol	0.5	0.9	1.7	0.0	-0.9	-1.3
Pack years adult smoking proportion	0.5	0.8	1.5	-0.2	1.2	-0.9
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.0	-0.7	0.5	-1.0
Trunk fat mass	0.5	2.3	3.5	1.9	1.7	0.9
Hearing difficulty/problems with background noise	0.5	0.7	1.2	1.1	-0.6	-0.9
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	3.3	-1.8	-0.2	-0.1
Heart attack	0.5	0.7	1.3	1.1	-0.5	-0.7
Pain all over the body in last month	0.5	0.5	1.3	1.1	0.2	0.6
Medication: Ramipril	0.5	0.6	1.5	-0.5	-0.4	-1.2
Neuroticism score	0.5	1.0	3.1	-0.1	0.2	-1.8
Pulse rate	0.5	0.8	2.3	-0.3	-1.5	-0.1
Depression (self-reported)	0.5	0.6	1.8	-0.3	-1.3	-0.3
Impedance of arm (left)	0.5	2.1	3.6	-1.9	-1.1	-1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	1.5	0.7	-1.2	-0.5
Headache pain in last month	0.5	0.8	2.1	0.4	-1.5	0.3
Number of children fathered	0.5	0.5	1.4	1.2	-0.1	0.5
Qualifications: College or University degree	0.5	1.6	4.2	-0.2	-2.1	0.7
Medication: Seretide 50 evohaler	0.5	0.6	1.1	0.8	1.1	-0.1
Heart disease (mother)	0.5	0.6	0.9	0.9	0.4	-0.9
Whole body fat mass	0.5	2.2	3.2	1.8	1.7	0.9
Age at last live birth	0.5	0.7	1.2	-1.1	-0.9	0.0
Medication: Aspirin	0.5	0.6	1.2	0.3	-0.8	-1.1
Average weekly red wine intake	0.5	0.7	1.5	-0.3	-0.7	-1.2
Qualifications: nursing, teaching	0.5	0.8	1.3	0.5	-0.9	1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.1	2.0	0.9	1.4	0.7
Arm fat mass (left)	0.5	2.1	3.9	2.0	1.4	0.7
Financial situation satisfaction	0.5	0.6	1.5	1.2	0.5	-0.0
Medication: Bendroflumethiazide	0.5	0.8	2.1	-0.4	-0.2	-1.5
Unable to work because of sickness or disability	0.5	0.7	1.5	-0.6	0.3	-1.2
Pack years of smoking	0.5	0.7	1.1	-0.3	1.0	-0.9
Impedance of whole body	0.5	2.4	5.0	-2.2	-0.7	-1.3
Depressed Affect (Nagel 2018)	0.4	0.9	1.2	0.9	-1.1	-0.8
Depression (Nagel 2018)	0.4	0.6	1.4	1.2	0.5	-0.4
Neuroticism (Nagel 2018)	0.4	0.9	1.3	1.1	0.4	-1.1
Worry (Nagel 2018)	0.4	0.8	1.4	1.0	1.2	-0.3
Ulcerative Colitis (UC)	0.4	0.7	1.7	-1.3	-0.5	-0.4
Coronary Artery Disease (CAD)	0.4	0.5	1.0	1.0	0.5	0.3
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.1	-1.1	-0.5	-0.0
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	1.1	0.1	0.6	-1.1
Average weekly fortified wine intake	0.4	0.5	1.0	1.0	-0.6	-0.2
Qualifications: CSEs or equivalent	0.4	0.5	0.6	0.5	-0.8	0.7
Sitting height	0.4	2.7	3.9	1.9	0.8	2.0
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	1.6	0.5	-0.1	-1.3
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.4	0.2	-1.2	0.1
Impedance of arm (right)	0.4	2.0	3.9	-2.0	-0.9	-1.1
Hip circumference	0.4	1.5	2.5	1.6	0.8	1.2
Alcohol intake versus 10 years previously	0.4	0.6	1.2	0.1	0.8	1.1
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	0.9	0.7	-0.7	-1.0
Arm fat mass (right)	0.4	1.6	3.0	1.7	1.3	0.4
Exposure to tobacco smoke at home	0.4	0.5	0.7	-0.8	0.8	0.3
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	1.5	0.4	-1.2	0.0
Glaucoma (self-reported)	0.4	0.4	0.6	-0.5	0.6	-0.8
Overall health rating	0.4	0.8	1.4	0.3	-1.0	-1.2
Average weekly champagne plus white wine intake	0.4	0.6	0.9	-0.7	-0.5	-0.9
Ever taken oral contraceptive pill	0.4	0.4	0.9	-0.9	-0.2	-0.5
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.0	0.2	-0.8	1.0
Illnesses of father: High blood pressure	0.4	0.5	1.4	0.1	0.5	-1.2
Risk taking	0.4	0.5	0.6	0.7	0.7	-0.7
Myopia	0.4	0.5	1.4	0.4	1.2	-0.3
Intelligence (Savage-Jansen 2018)	0.3	1.0	1.9	-0.9	-1.4	-0.7
Alzheimer’s Disease (in mother)	0.3	0.3	0.8	-0.4	-0.1	-0.9
Crohns Disease (2017)	0.3	0.6	1.5	-1.2	-0.4	-0.3
Age at First Birth	0.3	0.5	1.3	1.1	-0.0	0.3
Rheumatoid Arthritis	0.3	0.5	1.4	0.0	1.2	0.1
BMI	0.3	1.6	4.7	2.2	0.4	0.0
Waist Hip Ratio (WHR)	0.3	1.2	1.7	-1.3	-1.1	-0.8
Lung FVC	0.3	1.5	2.6	-1.4	1.6	-0.0
Relative age of first facial hair	0.3	0.5	0.9	-0.9	-0.2	-0.8
Diabetes (father)	0.3	0.4	1.2	-0.1	-1.1	-0.1
Current tobacco smoking	0.3	0.4	1.0	-0.5	-0.1	-1.0
Relative age voice broke	0.3	0.5	0.8	-0.8	0.4	-0.9
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	0.4	0.7	0.6	0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.8	1.9	-1.4	-0.6	-0.1
Body mass index (BMI)	0.3	1.3	2.3	1.5	1.2	0.1
Impedance of leg (left)	0.3	1.3	3.2	-1.8	-0.2	-0.8
Financial difficulties in last 2 years	0.3	0.5	1.1	-1.1	-0.5	0.0
Illnesses of siblings	0.3	0.4	0.7	-0.8	0.8	-0.1
Father’s age at death	0.3	0.4	0.7	-0.3	0.5	0.8
Asthma	0.3	0.7	1.5	0.7	-1.2	-0.0
Medication: Cholesterol lowering	0.3	0.5	1.5	1.2	0.0	-0.0
Tense / ‘highly strung’	0.3	0.5	0.9	0.2	1.0	-0.7
Loud music exposure frequency	0.3	0.3	0.7	0.4	0.1	0.8
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.4	-1.2	-0.0	0.5
Gout (self-reported)	0.3	0.4	0.7	0.6	-0.8	0.4
High blood pressure (siblings)	0.3	0.5	1.2	1.1	-0.5	-0.0
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	0.6	0.8	-0.0	0.6
Mouth/teeth dental problems: Loose teeth	0.3	0.4	0.6	0.4	-0.8	0.7
Medication: Blood pressure	0.3	0.5	1.1	1.1	0.6	-0.1
Medication: Omeprazole	0.3	0.3	0.8	0.2	-0.4	-0.9
Suffer from ‘nerves’	0.3	0.5	0.9	0.5	0.9	-0.7
Handedness (chirality/laterality): Left-handed	0.3	0.3	0.5	-0.7	-0.3	-0.6
Loneliness, isolation	0.3	0.4	0.7	0.8	-0.6	-0.5
Diabetes diagnosed by doctor	0.3	0.4	1.2	0.3	1.1	0.1
Eye problems/disorders: Cataract	0.3	0.3	0.6	-0.6	-0.7	0.2
Mother’s age at death	0.3	0.4	1.0	0.2	0.3	1.0
Medication: Lisinopril	0.3	0.3	0.7	-0.5	-0.8	0.2
Cholesterol lowering medication	0.3	0.5	0.5	0.7	0.6	-0.7
Crohns Disease (2012)	0.2	0.3	0.7	0.0	-0.3	-0.8
Height	0.2	3.7	6.5	1.7	1.3	2.5
Systolic Blood Pressure	0.2	0.8	1.7	-0.2	1.3	-0.8
Allergy or Eczema	0.2	0.4	0.6	0.7	-0.8	0.4
Cardiovascular Disease	0.2	0.8	2.2	-0.2	0.3	-1.5
Respiratory disease	0.2	0.4	0.6	0.8	-0.7	0.3
Hand grip strength (left)	0.2	0.5	0.8	-0.4	-0.7	0.9
Systolic blood pressure, automated reading	0.2	0.6	1.2	0.3	1.1	-0.8
Trunk fat percentage	0.2	0.6	1.2	0.8	1.1	-0.2
Fed-up feelings	0.2	0.4	0.7	0.8	0.1	-0.8
Waist circumference	0.2	0.7	1.8	1.4	0.4	0.4
Hair/balding pattern: Pattern 3	0.2	0.3	0.4	-0.6	-0.6	-0.4
Number of live births	0.2	0.3	0.6	0.1	0.8	-0.5
Length of working week for main job	0.2	0.3	0.7	0.9	-0.2	-0.0
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.4	-0.3	-0.4	0.6
Leg fat percentage (right)	0.2	0.8	1.3	1.1	1.1	0.0
Comparative body size at age 10	0.2	0.6	1.5	-0.4	1.2	-0.5
Eye problems/disorders: None of the above	0.2	0.3	0.8	0.9	-0.1	0.0
Neck or shoulder pain in last month	0.2	0.3	0.6	0.8	-0.2	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	1.0	0.7	0.1	1.0
Ever had bowel cancer screening	0.2	0.2	0.4	0.6	0.1	-0.6
Friendships satisfaction	0.2	0.2	0.6	0.3	-0.2	-0.8
Back pain experienced in last month	0.2	0.2	0.6	0.4	0.0	-0.8
Asthma (self-reported)	0.2	0.4	1.1	0.3	-1.1	-0.2
Smoking status: Current	0.2	0.3	0.4	-0.6	0.2	-0.6
Miserableness	0.2	0.4	1.0	1.0	0.4	0.1
Eye problems/disorders: Glaucoma	0.2	0.2	0.6	-0.2	0.8	0.1
Alcohol drinker status: Never	0.2	0.2	0.3	-0.6	0.2	-0.5
Commuting to job workplace: Cycle	0.2	0.2	0.5	-0.7	-0.1	0.3
Pain experienced in last month	0.2	0.4	0.6	-0.4	0.7	0.8
Basal cell carcinoma (self-reported)	0.2	0.3	0.7	-0.3	0.1	-0.9
Bipolar Disorder or Schizophrenia	0.1	0.2	0.4	-0.7	-0.2	-0.1
Schizophrenia (2018)	0.1	0.2	0.5	0.4	-0.7	-0.0
Alzheimer’s Disease (in father)	0.1	0.1	0.2	-0.3	-0.5	0.3
Alzheimer’s Disease (including proxy)	0.1	0.1	0.1	0.3	0.4	-0.1
Major Depression (MDD)	0.1	0.1	0.2	0.4	0.0	-0.1
Bipolar Disorder (2011)	0.1	0.1	0.1	-0.3	-0.2	-0.1
HDL Cholesterol	0.1	0.2	0.4	-0.1	-0.4	0.6
Blood Eosinophil Count	0.1	1.0	2.8	0.1	1.7	-0.6
Blood Platelet Count	0.1	1.7	3.8	-1.9	0.5	-1.0
Blood Red Count	0.1	0.5	1.2	0.0	-0.7	-1.1
Smoking Status	0.1	0.2	0.7	-0.2	-0.2	-0.8
Hair Pigment	0.1	2.8	3.8	-1.0	-1.9	-2.0
Tanning	0.1	1.6	2.2	1.5	1.4	0.7
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.3	0.6	0.4	-0.0
Angina	0.1	0.1	0.2	0.1	-0.1	-0.5
Medication for hormone replacement therapy	0.1	0.1	0.2	0.3	-0.3	0.4
Impedance of leg (right)	0.1	0.4	1.3	-1.1	0.0	-0.3
Maternal smoking around birth	0.1	0.1	0.4	-0.0	0.1	0.6
Stomach or abdominal pain in last month	0.1	0.1	0.3	-0.2	0.2	-0.6
Number of incorrect matches in round	0.1	0.2	0.5	0.7	0.1	0.4
Nervous feelings	0.1	0.2	0.4	-0.2	0.6	-0.1
Had other major operations	0.1	0.1	0.3	-0.0	-0.6	-0.2
Diabetes (self-reported)	0.1	0.2	0.4	-0.1	0.6	-0.4
Arm fat percentage (right)	0.1	0.5	0.7	0.9	0.7	-0.5
Happiness	0.1	0.1	0.2	0.4	-0.4	-0.1
Prospective memory result	0.1	0.2	0.4	-0.3	0.2	0.6
Pulse wave Arterial Stiffness index	0.1	0.1	0.1	0.4	-0.1	0.3
Medication: Ventolin 100micrograms inhaler	0.1	0.2	0.3	0.4	0.5	-0.3
Body fat percentage	0.1	0.5	0.8	0.8	0.9	-0.3
Pulse wave peak to peak time	0.1	0.1	0.2	-0.1	0.5	0.0
Angina (self-reported)	0.1	0.1	0.3	-0.1	-0.2	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.2	0.5	-0.3	0.3
Alcohol intake frequency.	0.1	0.3	0.8	-0.1	0.9	-0.3
Illness, injury, bereavement, stress in last 2 years	0.1	0.2	0.4	-0.3	0.6	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.2	-0.3	0.2	-0.4
Arm fat percentage (left)	0.1	0.5	0.8	0.9	0.6	-0.6
Mood swings	0.1	0.2	0.5	0.7	0.1	-0.5
Ever smoked	0.1	0.1	0.3	0.6	-0.2	0.1
Leg fat percentage (left)	0.1	0.5	1.0	0.6	1.0	-0.4
Diastolic blood pressure, automated reading	0.1	0.5	0.9	1.0	0.6	-0.2
Schizophrenia (2014)	0.0	0.1	0.2	0.3	-0.5	-0.2
Triglycerides	0.0	0.1	0.1	0.0	0.3	-0.4
Heel T-Score	0.0	0.0	0.0	-0.0	0.2	-0.2
Type 2 Diabetes (T2D) (2018)	0.0	0.0	0.1	0.3	-0.1	0.0
Ever had hysterectomy (womb removed)	0.0	0.0	0.1	-0.2	-0.1	-0.3
Past tobacco smoking	0.0	0.0	0.1	-0.2	-0.0	-0.3
Time employed in main current job	0.0	0.0	0.1	0.0	-0.3	0.0
Hair/balding pattern: Pattern 4	0.0	0.0	0.0	-0.2	-0.1	-0.1
Pulse wave reflection index	0.0	0.0	0.1	0.3	0.2	-0.1
Pulse rate, automated reading	0.0	0.0	0.1	-0.3	-0.2	-0.1
Illnesses of siblings: Diabetes	0.0	0.1	0.1	-0.3	-0.1	-0.3
Smoking status: Previous	0.0	0.1	0.1	0.4	0.2	0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.0	0.0	0.1	-0.2	0.2	-0.2
Medication: Atorvastatin	0.0	0.0	0.1	-0.3	0.1	-0.0
Average weekly beer plus cider intake	0.0	0.1	0.2	0.4	0.0	-0.2
Heart disease (siblings)	0.0	0.0	0.1	-0.1	-0.2	0.2

Hub : Genes

CXCL6

Models

Trait associations