Best TWAS P=1.37e-09 · Best GWAS P=2.63e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Heart Left Ventricle | SNCA | 0.16 | 0.15 | lasso | 8 | 0.14 | 5.3e-08 | 6.3 | 6.1 | 1.4e-09 | 0.99 | 0.00 | 1.00 | TRUE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | SNCA | 0.05 | 0.05 | blup | 101 | 0.04 | 1.1e-05 | 3.9 | -5.5 | 2.9e-08 | -0.94 | 0.01 | 0.98 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SNCA | 0.16 | 0.16 | enet | 9 | 0.17 | 3.1e-17 | 5.6 | 5.6 | 1.8e-08 | 0.90 | 0.10 | 0.90 | FALSE |