Best TWAS P=4.6e-08 · Best GWAS P=6.33e-07 conditioned to 0.0467
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Sigmoid | RP11-522I20.3 | 0.43 | 0.13 | lasso | 12 | 0.19 | 3.1e-07 | -4.7 | -5.5 | 4.6e-08 | 0.63 | 0.03 | 0.95 | TRUE |
| 2 | GTEx | Colon Transverse | RP11-522I20.3 | 0.25 | 0.23 | lasso | 4 | 0.20 | 4.4e-10 | -4.7 | -5.3 | 1.1e-07 | 0.34 | 0.02 | 0.96 | FALSE |
| 3 | GTEx | Esophagus Gastroesophageal Junction | RP11-522I20.3 | 0.14 | 0.17 | lasso | 4 | 0.15 | 3.3e-06 | -4.7 | -5.3 | 1.1e-07 | 0.41 | 0.02 | 0.90 | FALSE |