[Hub]/) : Traits : Worry (Nagel 2018) :

chr9:95,502,571-96,898,436

Best TWAS P=8.2e-10 · Best GWAS P=4.18e-09 conditioned to 0.383

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum RP11-165J3.6 0.26 0.13 lasso 6 0.13 4.2e-07 4.7 5.5 3.9e-08 0.70 0.23 0.76 FALSE
2 GTEx Artery Aorta RP11-165J3.6 0.23 0.22 enet 10 0.22 2.3e-12 5.8 5.7 9.6e-09 0.86 0.02 0.98 FALSE
3 GTEx Artery Tibial RP11-165J3.6 0.22 0.20 lasso 2 0.19 4.9e-15 5.8 5.7 1.2e-08 0.85 0.01 0.99 FALSE
4 GTEx Brain Caudate basal ganglia RP11-165J3.6 0.47 0.33 lasso 7 0.31 1.0e-09 5.8 5.4 7.5e-08 0.83 0.01 0.99 FALSE
5 GTEx Brain Cerebellum RP11-165J3.6 0.44 0.31 lasso 7 0.28 5.0e-09 5.8 5.4 5.9e-08 0.86 0.01 0.99 FALSE
6 GTEx Brain Frontal Cortex BA9 RP11-165J3.6 0.41 0.14 lasso 6 0.20 6.1e-06 5.8 5.7 1.2e-08 0.84 0.01 0.99 FALSE
7 GTEx Brain Nucleus accumbens basal ganglia RP11-165J3.6 0.31 0.11 lasso 6 0.16 5.4e-05 5.8 5.7 1.4e-08 0.79 0.01 0.93 FALSE
8 GTEx Breast Mammary Tissue RP11-165J3.6 0.28 0.11 enet 24 0.13 2.7e-07 5.5 5.5 4.9e-08 0.85 0.02 0.98 FALSE
9 GTEx Breast Mammary Tissue (Female) RP11-165J3.6 0.21 0.02 lasso 3 0.00 2.3e-01 5.5 5.7 1.4e-08 0.88 0.03 0.68 FALSE
10 GTEx Colon Sigmoid RP11-165J3.6 0.31 0.12 enet 17 0.16 1.8e-06 5.7 5.2 1.5e-07 0.83 0.01 0.98 FALSE
11 GTEx Colon Transverse RP11-165J3.6 0.37 0.20 lasso 4 0.18 3.6e-09 5.8 6.1 8.2e-10 0.89 0.01 0.99 TRUE
12 GTEx Esophagus Gastroesophageal Junction RP11-165J3.6 0.34 0.26 lasso 8 0.27 3.0e-10 5.8 5.9 4.8e-09 0.88 0.01 0.99 FALSE
13 GTEx Heart Atrial Appendage RP11-165J3.6 0.38 0.21 lasso 7 0.25 8.7e-12 5.5 5.9 3.6e-09 0.94 0.01 0.99 FALSE
14 GTEx Heart Left Ventricle RP11-165J3.6 0.13 0.06 lasso 5 0.05 1.9e-03 5.8 5.3 1.2e-07 0.82 0.02 0.96 FALSE
15 GTEx Lung RP11-165J3.6 0.25 0.16 lasso 7 0.17 4.1e-13 5.8 5.9 3.1e-09 0.89 0.01 0.99 FALSE
16 GTEx Pituitary RP11-165J3.6 0.49 0.22 lasso 8 0.29 6.9e-08 5.5 5.5 3.7e-08 0.94 0.01 0.99 FALSE
17 GTEx Skin Not Sun Exposed Suprapubic RP11-165J3.6 0.27 0.14 lasso 7 0.19 1.4e-10 5.8 5.9 3.9e-09 0.94 0.01 0.99 FALSE
18 GTEx Skin Sun Exposed Lower leg RP11-165J3.6 0.32 0.27 lasso 5 0.35 6.8e-30 5.5 5.9 4.7e-09 0.96 0.01 0.99 FALSE
19 GTEx Thyroid RP11-165J3.6 0.35 0.27 lasso 3 0.29 1.2e-22 5.8 5.8 5.2e-09 0.86 0.01 0.99 FALSE