Best TWAS P=1.24e-07 · Best GWAS P=2.25e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | PRPS1P2 | 0.06 | 0.06 | enet | 6 | 0.05 | 9.2e-05 | -5.2 | -5.1 | 2.8e-07 | 1.00 | 0.02 | 0.97 | FALSE |
| 2 | GTEx | Breast Mammary Tissue (Female) | PPP6C | 0.14 | 0.04 | lasso | 4 | 0.04 | 3.1e-02 | -5.1 | 5.2 | 1.9e-07 | -0.97 | 0.04 | 0.88 | FALSE |
| 3 | GTEx | Cells Transformed fibroblasts | PRPS1P2 | 0.09 | 0.11 | enet | 8 | 0.13 | 9.6e-10 | -4.9 | -5.3 | 1.2e-07 | 0.97 | 0.04 | 0.96 | TRUE |
| 4 | GTEx | Pancreas | PRPS1P2 | 0.16 | 0.13 | lasso | 6 | 0.12 | 8.7e-06 | -5.2 | -5.1 | 3.1e-07 | 0.99 | 0.02 | 0.97 | FALSE |