[Hub]/) : Traits : Blood Platelet Count :

chr6:78,880,271-80,486,611

Best TWAS P=1.19e-07 · Best GWAS P=1.98e-07 conditioned to 0.274

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial IRAK1BP1 0.11 0.15 lasso 4 0.16 1.4e-12 -4.8 -5.1 2.9e-07 -0.80 0.04 0.95 FALSE
2 GTEx Brain Hypothalamus IRAK1BP1 0.21 0.16 enet 28 0.18 4.4e-05 5.2 -5.2 2.1e-07 -0.89 0.04 0.93 FALSE
3 GTEx Breast Mammary Tissue (Male) IRAK1BP1 0.10 0.00 enet 2 0.00 3.9e-01 5.2 -5.2 2.2e-07 -1.00 0.04 0.46 FALSE
4 GTEx Colon Transverse IRAK1BP1 0.11 0.18 lasso 2 0.16 4.0e-08 5.1 -5.1 2.7e-07 -0.91 0.02 0.98 FALSE
5 GTEx Esophagus Muscularis IRAK1BP1 0.17 0.22 lasso 4 0.22 1.6e-13 -4.9 -5.1 2.7e-07 -0.79 0.04 0.95 FALSE
6 GTEx Nerve Tibial IRAK1BP1 0.12 0.16 lasso 6 0.14 8.8e-10 5.1 -5.3 1.2e-07 -0.89 0.03 0.96 TRUE
7 GTEx Skin Sun Exposed Lower leg IRAK1BP1 0.17 0.18 lasso 4 0.18 2.0e-14 5.1 -5.2 2.3e-07 -0.91 0.02 0.98 FALSE
8 METSIM Adipose IRAK1BP1 0.15 0.17 lasso 6 0.16 1.1e-23 5.1 -5.2 2.3e-07 -0.94 0.02 0.98 FALSE
9 YFS Blood PHIP 0.05 0.07 lasso 5 0.08 1.8e-24 5.1 -5.2 1.6e-07 -0.96 0.02 0.98 FALSE
10 The Cancer Genome Atlas Lung Adenocarcinoma IRAK1BP1 0.03 0.03 lasso 4 0.02 1.2e-03 5.1 -5.2 2.5e-07 -0.90 0.02 0.80 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma PHIP 0.11 0.08 blup 75 0.07 2.6e-07 -5.0 -5.2 2.7e-07 -0.70 0.03 0.97 FALSE