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chr6:51,528,984-53,664,707

Best TWAS P=4.63e-48 · Best GWAS P=2.03e-44 conditioned to 0.405

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	PAQR8	0.09	0.01	enet	17	0.05	2.9e-05	3.66	-6.6	4.1e-11	-0.44	0.14	0.24	FALSE
2	GTEx	Artery Aorta	PAQR8	0.21	0.02	enet	22	0.04	1.9e-03	8.62	10.5	1.1e-25	0.03	0.30	0.04	TRUE
3	GTEx	Cells Transformed fibroblasts	PAQR8	0.27	0.13	enet	17	0.21	9.4e-16	-6.19	7.2	6.7e-13	0.03	1.00	0.00	FALSE
4	GTEx	Colon Sigmoid	TRAM2-AS1	0.20	0.02	lasso	4	0.02	7.4e-02	3.22	5.8	5.8e-09	0.00	0.08	0.15	FALSE
5	GTEx	Esophagus Mucosa	RP1-152L7.5	0.13	0.04	lasso	3	0.05	3.8e-04	11.37	-10.6	2.2e-26	-0.63	0.25	0.67	FALSE
6	METSIM	Adipose	FBXO9	0.09	0.00	bslmm	538	0.01	1.6e-02	-0.53	5.2	2.5e-07	0.03	0.07	0.02	TRUE
7	NTR	Blood	TRAM2	0.04	0.02	blup	589	0.02	9.3e-08	3.60	-8.4	2.9e-17	-0.03	0.99	0.00	TRUE
8	YFS	Blood	EFHC1	0.04	0.00	enet	18	0.02	2.2e-06	5.66	-7.6	3.4e-14	0.00	0.45	0.01	FALSE
9	YFS	Blood	GSTA4	0.02	0.01	blup	511	0.01	1.0e-04	1.14	-6.8	7.4e-12	-0.37	0.61	0.17	FALSE
10	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	GSTA1	0.04	0.03	blup	34	0.04	4.0e-04	-12.27	-14.2	1.7e-45	-0.84	0.05	0.77	FALSE
11	The Cancer Genome Atlas	Breast Invasive Carcinoma	GSTA1	0.02	0.03	blup	34	0.03	1.1e-06	13.49	-14.2	7.6e-46	-0.92	0.02	0.98	FALSE
12	The Cancer Genome Atlas	Colon Adenocarcinoma	GSTA1	0.08	0.06	blup	34	0.09	7.2e-06	13.65	-14.6	4.6e-48	-0.90	0.07	0.92	TRUE
13	The Cancer Genome Atlas	Esophageal Carcinoma	GSTA1	0.10	0.07	enet	11	0.09	7.0e-04	13.92	-14.5	1.5e-47	-0.95	0.01	0.97	FALSE
14	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PAQR8	0.07	0.06	blup	90	0.06	1.6e-07	3.66	7.0	1.9e-12	0.04	0.29	0.71	FALSE
15	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	GSTA1	0.05	0.04	enet	10	0.05	1.1e-03	13.65	-13.1	5.1e-39	-0.82	0.04	0.34	FALSE
16	The Cancer Genome Atlas	Brain Lower Grade Glioma	EFHC1	0.05	0.00	blup	126	0.02	3.4e-03	5.39	5.3	1.2e-07	0.04	0.05	0.43	FALSE
17	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	GSTA1	0.11	0.05	blup	34	0.08	1.6e-04	13.51	-12.9	4.3e-38	-0.84	0.02	0.91	FALSE
18	The Cancer Genome Atlas	Lung Adenocarcinoma	GSTA1	0.06	0.11	lasso	4	0.11	1.5e-12	13.49	-13.5	3.0e-41	-0.84	0.30	0.70	FALSE
19	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	GSTA1	0.10	0.18	blup	34	0.18	1.7e-12	13.49	-14.1	2.3e-45	-0.92	0.07	0.93	FALSE
20	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	GSTA1	0.16	0.17	lasso	4	0.12	1.1e-05	13.62	-13.9	5.0e-44	-0.84	0.09	0.89	FALSE
21	The Cancer Genome Atlas	Prostate Adenocarcinoma	GSTA1	0.04	0.03	blup	34	0.06	1.5e-06	13.61	-14.2	1.7e-45	-0.86	0.12	0.88	FALSE
22	The Cancer Genome Atlas	Prostate Adenocarcinoma	PAQR8	0.04	0.03	enet	6	0.03	6.9e-04	8.62	6.9	3.9e-12	0.03	0.00	0.96	FALSE
23	The Cancer Genome Atlas	Rectum Adenocarcinoma	GSTA1	0.15	0.11	blup	34	0.08	5.2e-03	13.62	-13.5	1.4e-41	-0.89	0.02	0.64	FALSE
24	The Cancer Genome Atlas	Stomach Adenocarcinoma	GSTA1	0.12	0.10	enet	4	0.11	1.4e-08	13.62	-13.7	5.3e-43	-0.82	0.30	0.70	FALSE
25	The Cancer Genome Atlas	Thyroid Carcinoma	EFHC1	0.05	0.03	enet	14	0.04	1.0e-04	2.76	6.1	1.1e-09	-0.03	0.14	0.51	FALSE
26	The Cancer Genome Atlas	Thyroid Carcinoma	GSTA1	0.04	0.05	blup	34	0.06	1.2e-06	13.66	-13.9	5.0e-44	-0.94	0.02	0.97	FALSE
27	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	GSTA1	0.13	0.15	blup	34	0.15	6.1e-05	13.65	-14.3	2.9e-46	-0.93	0.03	0.96	FALSE