TWAS
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Genes
Traits
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Traits
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Blood Platelet Count
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chr6:160,071,844-161,571,560
Best TWAS P=5.13e-08 · Best GWAS P=7.67e-12 conditioned to 8.26e-07
160M
160.2M
160.4M
160.6M
160.8M
161M
161.2M
161.4M
161.6M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Testis
SLC22A3
0.19
0.01
lasso
14
0.05
0.0026
3.3
5.5
5.1e-08
0.45
0.85
0.04
TRUE
2
The Cancer Genome Atlas
Ovarian Serous Cystadenocarcinoma
LPAL2
0.07
0.00
blup
74
0.04
0.0011
5.5
-5.3
1.3e-07
-0.37
0.01
0.87
FALSE