Best TWAS P=5.13e-08 · Best GWAS P=7.67e-12 conditioned to 8.26e-07
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Testis | SLC22A3 | 0.19 | 0.01 | lasso | 14 | 0.05 | 0.0026 | 3.3 | 5.5 | 5.1e-08 | 0.45 | 0.85 | 0.04 | TRUE |
2 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | LPAL2 | 0.07 | 0.00 | blup | 74 | 0.04 | 0.0011 | 5.5 | -5.3 | 1.3e-07 | -0.37 | 0.01 | 0.87 | FALSE |