Best TWAS P=8.65e-12 · Best GWAS P=3.82e-12 conditioned to 0.0138
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | SNX9 | 0.09 | 0.06 | lasso | 4 | 0.05 | 9.7e-07 | -6.3 | 6.3 | 3.6e-10 | -0.88 | 0.05 | 0.94 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | SNX9 | 0.04 | 0.01 | enet | 11 | 0.02 | 6.9e-04 | -6.6 | 6.0 | 1.9e-09 | -0.82 | 0.04 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | TULP4 | 0.09 | 0.05 | blup | 148 | 0.04 | 2.0e-05 | -3.6 | 6.0 | 1.9e-09 | 0.00 | 0.04 | 0.31 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | SNX9 | 0.04 | 0.01 | blup | 111 | 0.03 | 6.3e-04 | -5.0 | 6.8 | 8.7e-12 | -0.80 | 0.12 | 0.80 | TRUE |