TWAS
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Traits
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Traits
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Blood Platelet Count
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chr6:157,713,662-159,178,345
Best TWAS P=8.65e-12 · Best GWAS P=3.82e-12 conditioned to 0.0138
157.8M
158M
158.2M
158.4M
158.6M
158.8M
159M
159.2M
0
2
4
6
8
10
12
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Thyroid Carcinoma
SNX9
0.04
0.01
blup
111
0.03
6.3e-04
-5.0
6.8
8.7e-12
-0.80
0.12
0.80
TRUE
3
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
TULP4
0.09
0.05
blup
148
0.04
2.0e-05
-3.6
6.0
1.9e-09
0.00
0.04
0.31
TRUE
1
CommonMind
Brain Pre-frontal Cortex
SNX9
0.09
0.06
lasso
4
0.05
9.7e-07
-6.3
6.3
3.6e-10
-0.88
0.05
0.94
FALSE
2
ROSMAP
Brain Pre-frontal Cortex
SNX9
0.04
0.01
enet
11
0.02
6.9e-04
-6.6
6.0
1.9e-09
-0.82
0.04
0.96
FALSE