[Hub]/) : Traits : Blood Platelet Count : ← →

chr7:35,070,620-37,033,221

Best TWAS P=5.84e-13 · Best GWAS P=1.4e-22 conditioned to 8.32e-11

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Coronary RP11-379H18.1 0.16 0.18 lasso 2 0.15 7.0e-06 5.1 -5.6 2.7e-08 0.08 0.66 0.02 FALSE
2 GTEx Cells Transformed fibroblasts RP11-379H18.1 0.29 0.28 lasso 7 0.28 1.4e-21 5.1 -5.3 1.0e-07 0.09 1.00 0.00 FALSE
3 GTEx Esophagus Mucosa SEPT7 0.11 0.13 lasso 2 0.11 1.5e-07 -7.2 7.2 5.8e-13 0.08 1.00 0.00 TRUE
4 GTEx Muscle Skeletal RP11-379H18.1 0.22 0.18 enet 19 0.16 1.2e-15 5.1 -5.4 6.3e-08 0.11 1.00 0.00 FALSE
5 GTEx Nerve Tibial RP11-379H18.1 0.20 0.12 lasso 5 0.10 7.2e-08 5.0 -5.1 2.9e-07 0.11 1.00 0.00 FALSE
6 GTEx Skin Sun Exposed Lower leg RP11-379H18.1 0.14 0.14 lasso 3 0.14 2.1e-11 5.0 -5.4 5.2e-08 0.09 1.00 0.00 FALSE
7 GTEx Spleen RP11-379H18.1 0.44 0.22 lasso 7 0.20 8.9e-06 5.1 -5.3 1.2e-07 0.09 0.19 0.04 FALSE
8 GTEx Stomach RP11-379H18.1 0.13 0.11 lasso 5 0.09 3.8e-05 5.0 -5.8 4.9e-09 0.06 0.72 0.01 FALSE
9 GTEx Vagina RP11-379H18.1 0.30 0.26 lasso 16 0.20 3.1e-05 -5.4 -6.3 2.5e-10 0.02 0.26 0.17 FALSE
10 GTEx Whole Blood RP11-379H18.1 0.07 0.04 lasso 3 0.02 9.1e-03 -4.5 -5.4 6.5e-08 0.09 0.72 0.02 FALSE
11 METSIM Adipose EEPD1 0.15 0.04 enet 44 0.10 3.4e-14 -3.1 -5.8 8.3e-09 -0.37 0.96 0.04 TRUE
12 The Cancer Genome Atlas Prostate Adenocarcinoma EEPD1 0.06 0.00 blup 168 0.03 5.6e-04 -3.1 5.2 2.1e-07 0.24 0.02 0.76 TRUE
13 The Cancer Genome Atlas Rectum Adenocarcinoma HERPUD2 0.21 0.08 blup 75 0.14 3.0e-04 -4.1 -5.3 1.4e-07 0.02 0.06 0.11 FALSE