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chr7:71,935,903-73,843,516

Best TWAS P=1.44e-21 · Best GWAS P=1.42e-19 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
9	GTEx	Spleen	NCF1B	0.22	0.10	enet	9	0.08	5.1e-03	-8.1	9.5	1.4e-21	-0.69	0.02	0.60	TRUE
1	GTEx	Adipose Subcutaneous	MLXIPL	0.11	0.07	enet	16	0.07	1.6e-06	-9.0	-9.1	7.6e-20	0.90	0.01	0.99	TRUE
7	GTEx	Skin Not Sun Exposed Suprapubic	MLXIPL	0.11	0.11	lasso	3	0.06	2.7e-04	-8.8	-8.4	4.0e-17	0.93	0.01	0.98	TRUE
6	GTEx	Lung	MLXIPL	0.10	0.07	enet	14	0.07	6.3e-06	-9.0	-7.6	3.9e-14	0.65	0.01	0.98	TRUE
14	METSIM	Adipose	BCL7B	0.10	0.02	enet	20	0.05	1.2e-07	-9.0	-5.9	3.6e-09	0.72	0.01	0.99	TRUE
13	METSIM	Adipose	ABHD11	0.08	0.08	enet	22	0.09	2.5e-13	4.9	-5.8	5.9e-09	-0.02	1.00	0.00	TRUE
11	GTEx	Testis	VPS37D	0.15	0.01	lasso	5	0.03	2.7e-02	5.4	5.7	1.6e-08	-0.24	0.13	0.05	TRUE
4	GTEx	Cells Transformed fibroblasts	MLXIPL	0.13	0.06	enet	6	0.09	2.2e-07	-8.8	-9.3	9.0e-21	0.90	0.01	0.99	FALSE
12	GTEx	Thyroid	MLXIPL	0.23	0.14	lasso	7	0.15	2.1e-11	-9.0	-9.3	1.3e-20	0.91	0.01	0.99	FALSE
8	GTEx	Skin Sun Exposed Lower leg	MLXIPL	0.12	0.09	lasso	4	0.06	6.1e-06	-8.7	-9.2	4.8e-20	0.94	0.01	0.99	FALSE
15	METSIM	Adipose	MLXIPL	0.12	0.14	lasso	4	0.13	1.8e-19	-8.5	-9.0	1.9e-19	0.83	0.03	0.97	FALSE
2	GTEx	Adipose Visceral Omentum	MLXIPL	0.16	0.02	lasso	3	0.03	7.8e-03	-9.0	-9.0	3.2e-19	0.98	0.00	1.00	FALSE
18	The Cancer Genome Atlas	Lung Adenocarcinoma	MLXIPL	0.04	0.03	lasso	1	0.02	2.3e-03	-8.5	-8.5	2.5e-17	0.74	0.00	0.91	FALSE
17	The Cancer Genome Atlas	Breast Invasive Carcinoma	MLXIPL	0.06	0.05	lasso	2	0.05	5.1e-10	-8.5	-8.1	5.9e-16	0.74	0.00	1.00	FALSE
10	GTEx	Testis	MLXIPL	0.10	0.00	lasso	3	0.00	3.3e-01	-5.2	-7.6	2.4e-14	0.63	0.02	0.64	FALSE
19	The Cancer Genome Atlas	Prostate Adenocarcinoma	MLXIPL	0.08	0.05	enet	4	0.05	5.3e-06	-8.5	-7.3	3.1e-13	0.68	0.00	0.98	FALSE
20	The Cancer Genome Atlas	Thyroid Carcinoma	BCL7B	0.05	0.01	blup	5	0.03	1.3e-03	-8.5	7.2	6.1e-13	-0.44	0.00	0.63	FALSE
3	GTEx	Adipose Visceral Omentum	NSUN5	0.07	0.03	enet	11	0.04	4.0e-03	-8.5	-6.2	4.5e-10	0.69	0.01	0.84	FALSE
5	GTEx	Heart Left Ventricle	MLXIPL	0.14	0.00	enet	24	0.01	1.3e-01	-2.4	-6.0	2.0e-09	0.57	0.06	0.67	FALSE
16	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	STX1A	0.03	0.02	lasso	1	0.01	2.9e-02	5.5	5.5	3.1e-08	-0.21	0.00	0.79	FALSE