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chr1:77,655,651-79,300,939

Best TWAS P=6.39e-10 · Best GWAS P=8.78e-10 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Cells EBV-transformed lymphocytes	NEXN	0.23	0.10	lasso	3	0.08	1.4e-03	-5.9	-6.2	6.4e-10	0.95	0.01	0.94	TRUE
2	GTEx	Lung	GIPC2	0.15	0.09	enet	17	0.12	2.5e-09	-5.5	6.1	1.3e-09	-0.84	0.04	0.96	FALSE
7	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	DNAJB4	0.05	0.03	lasso	3	0.02	3.3e-03	-5.7	-6.0	2.4e-09	0.84	0.00	0.99	FALSE
5	GTEx	Spleen	GIPC2	0.43	0.07	enet	19	0.22	2.9e-06	-5.2	6.0	2.5e-09	-0.74	0.07	0.92	FALSE
3	GTEx	Nerve Tibial	DNAJB4	0.08	0.07	lasso	3	0.07	1.3e-05	-5.8	-5.9	3.0e-09	0.85	0.02	0.98	FALSE
8	The Cancer Genome Atlas	Colon Adenocarcinoma	GIPC2	0.04	0.01	blup	65	0.00	2.5e-01	-5.0	5.9	3.0e-09	-0.73	0.02	0.67	FALSE
11	The Cancer Genome Atlas	Prostate Adenocarcinoma	GIPC2	0.10	0.11	blup	64	0.13	1.1e-13	-5.3	5.9	4.4e-09	-0.76	0.02	0.98	FALSE
6	ROSMAP	Brain Pre-frontal Cortex	DNAJB4	0.08	0.09	lasso	2	0.09	1.3e-11	-5.7	-5.8	7.4e-09	0.80	0.03	0.97	FALSE
4	GTEx	Skin Sun Exposed Lower leg	DNAJB4	0.07	0.05	lasso	5	0.05	6.5e-05	-5.8	-5.7	1.2e-08	0.83	0.02	0.97	FALSE
9	The Cancer Genome Atlas	Brain Lower Grade Glioma	DNAJB4	0.08	0.07	lasso	1	0.06	9.3e-08	-5.7	-5.7	1.2e-08	0.78	0.00	1.00	FALSE
12	The Cancer Genome Atlas	Testicular Germ Cell Tumors	DNAJB4	0.24	0.14	lasso	1	0.11	1.1e-04	-5.7	-5.7	1.2e-08	0.78	0.00	0.98	FALSE
10	The Cancer Genome Atlas	Brain Lower Grade Glioma	GIPC2	0.02	0.02	lasso	3	0.02	1.0e-03	-5.2	5.5	5.1e-08	-0.64	0.04	0.90	FALSE
13	The Cancer Genome Atlas	Thyroid Carcinoma	GIPC2	0.07	0.05	blup	64	0.06	1.5e-06	-3.9	5.2	1.9e-07	-0.60	0.29	0.57	FALSE