[Hub]/) : Traits : Blood Platelet Count : ← →

chr1:77,655,651-79,300,939

Best TWAS P=6.39e-10 · Best GWAS P=8.78e-10 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells EBV-transformed lymphocytes NEXN 0.23 0.10 lasso 3 0.08 1.4e-03 -5.9 -6.2 6.4e-10 0.95 0.01 0.94 TRUE
2 GTEx Lung GIPC2 0.15 0.09 enet 17 0.12 2.5e-09 -5.5 6.1 1.3e-09 -0.84 0.04 0.96 FALSE
3 GTEx Nerve Tibial DNAJB4 0.08 0.07 lasso 3 0.07 1.3e-05 -5.8 -5.9 3.0e-09 0.85 0.02 0.98 FALSE
4 GTEx Skin Sun Exposed Lower leg DNAJB4 0.07 0.05 lasso 5 0.05 6.5e-05 -5.8 -5.7 1.2e-08 0.83 0.02 0.97 FALSE
5 GTEx Spleen GIPC2 0.43 0.07 enet 19 0.22 2.9e-06 -5.2 6.0 2.5e-09 -0.74 0.07 0.92 FALSE
6 ROSMAP Brain Pre-frontal Cortex DNAJB4 0.08 0.09 lasso 2 0.09 1.3e-11 -5.7 -5.8 7.4e-09 0.80 0.03 0.97 FALSE
7 The Cancer Genome Atlas Bladder Urothelial Carcinoma DNAJB4 0.05 0.03 lasso 3 0.02 3.3e-03 -5.7 -6.0 2.4e-09 0.84 0.00 0.99 FALSE
8 The Cancer Genome Atlas Colon Adenocarcinoma GIPC2 0.04 0.01 blup 65 0.00 2.5e-01 -5.0 5.9 3.0e-09 -0.73 0.02 0.67 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma DNAJB4 0.08 0.07 lasso 1 0.06 9.3e-08 -5.7 -5.7 1.2e-08 0.78 0.00 1.00 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma GIPC2 0.02 0.02 lasso 3 0.02 1.0e-03 -5.2 5.5 5.1e-08 -0.64 0.04 0.90 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma GIPC2 0.10 0.11 blup 64 0.13 1.1e-13 -5.3 5.9 4.4e-09 -0.76 0.02 0.98 FALSE
12 The Cancer Genome Atlas Testicular Germ Cell Tumors DNAJB4 0.24 0.14 lasso 1 0.11 1.1e-04 -5.7 -5.7 1.2e-08 0.78 0.00 0.98 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma GIPC2 0.07 0.05 blup 64 0.06 1.5e-06 -3.9 5.2 1.9e-07 -0.60 0.29 0.57 FALSE