[Hub]/) : Traits : Blood Platelet Count :

chr1:64,515,379-66,803,080

Best TWAS P=8.2e-12 · Best GWAS P=7.38e-12 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex JAK1 0.09 0.10 lasso 4 0.11 4.7e-13 -6.8 6.6 5.4e-11 -0.98 0.00 1.00 FALSE
2 GTEx Brain Cerebellum JAK1 0.48 0.27 enet 22 0.39 1.6e-12 -6.3 6.8 1.1e-11 -0.93 0.02 0.98 FALSE
3 GTEx Brain Cortex JAK1 0.34 0.21 lasso 2 0.23 4.6e-07 -6.8 6.8 8.2e-12 -1.00 0.01 0.99 TRUE
4 ROSMAP Brain Pre-frontal Cortex LEPR 0.09 0.07 blup 505 0.06 4.6e-08 3.8 -5.2 2.5e-07 0.09 1.00 0.00 TRUE
5 ROSMAP Brain Pre-frontal Cortex JAK1 0.12 0.13 bslmm 478 0.12 3.6e-15 -6.5 6.8 1.3e-11 -0.96 0.02 0.98 FALSE
6 ROSMAP Brain Pre-frontal Cortex RAVER2 0.33 0.32 bslmm 466 0.38 1.0e-51 -5.0 5.5 3.3e-08 -0.62 0.99 0.01 FALSE
7 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma JAK1 0.09 0.08 lasso 1 0.07 1.8e-04 -5.3 5.2 1.5e-07 -0.65 0.06 0.71 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma JAK1 0.08 0.08 blup 91 0.08 5.2e-09 -6.8 5.6 2.2e-08 -0.84 0.00 1.00 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma RAVER2 0.04 0.03 blup 77 0.05 1.0e-06 -6.5 6.5 9.5e-11 -0.88 0.02 0.98 FALSE