[Hub]/) : Traits : Blood Platelet Count :

chr9:18,355,044-19,797,850

Best TWAS P=5.07e-14 · Best GWAS P=1.34e-14 conditioned to 0.0445

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous HAUS6 0.14 0.13 lasso 4 0.12 2.3e-10 5.8 -6.8 1.3e-11 -0.90 0.01 0.99 FALSE
2 GTEx Adipose Visceral Omentum HAUS6 0.15 0.02 lasso 5 0.05 1.4e-03 7.5 -6.9 6.4e-12 -0.78 0.02 0.90 FALSE
3 GTEx Artery Aorta HAUS6 0.14 0.05 lasso 5 0.07 8.7e-05 5.8 -6.0 1.7e-09 -0.83 0.02 0.97 FALSE
4 GTEx Artery Tibial HAUS6 0.14 0.14 lasso 1 0.14 3.7e-11 5.8 -5.8 6.4e-09 -0.83 0.65 0.35 FALSE
5 GTEx Breast Mammary Tissue HAUS6 0.12 0.06 lasso 2 0.05 1.7e-03 7.3 -6.9 5.2e-12 -0.94 0.02 0.97 FALSE
6 GTEx Cells Transformed fibroblasts HAUS6 0.28 0.17 lasso 8 0.20 1.4e-14 7.6 -7.5 5.1e-14 -0.92 0.01 0.99 TRUE
7 GTEx Nerve Tibial HAUS6 0.14 0.04 enet 22 0.08 1.9e-06 4.1 -5.5 4.9e-08 -0.76 0.05 0.95 FALSE
8 GTEx Thyroid HAUS6 0.12 0.05 lasso 3 0.02 5.3e-03 5.8 -6.3 2.3e-10 -0.88 0.01 0.98 FALSE
9 METSIM Adipose HAUS6 0.06 0.04 bslmm 666 0.03 4.9e-06 7.5 -7.2 8.8e-13 -0.87 0.02 0.98 FALSE
10 The Cancer Genome Atlas Breast Invasive Carcinoma HAUS6 0.04 0.03 blup 87 0.05 4.1e-10 7.5 -7.2 4.8e-13 -0.88 0.02 0.98 FALSE
11 The Cancer Genome Atlas Colon Adenocarcinoma HAUS6 0.05 0.04 lasso 2 0.03 5.1e-03 -6.4 -6.9 6.3e-12 -0.74 0.05 0.71 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma HAUS6 0.04 0.06 lasso 2 0.05 9.1e-07 5.8 -5.8 6.1e-09 -0.83 0.12 0.88 FALSE
13 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma HAUS6 0.09 0.04 lasso 5 0.07 1.2e-04 4.0 -7.0 1.8e-12 -0.80 0.05 0.89 FALSE
14 The Cancer Genome Atlas Lung Adenocarcinoma HAUS6 0.06 0.04 blup 87 0.04 6.9e-06 7.3 -6.1 1.2e-09 -0.88 0.02 0.98 FALSE
15 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma FAM154A 0.06 0.00 blup 174 0.01 1.3e-01 7.3 -6.4 1.7e-10 -0.87 0.02 0.92 FALSE
16 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma HAUS6 0.07 0.00 enet 7 0.04 1.3e-03 1.4 -5.6 1.8e-08 -0.60 0.03 0.84 FALSE
17 The Cancer Genome Atlas Prostate Adenocarcinoma HAUS6 0.12 0.09 blup 87 0.10 1.4e-10 5.8 -6.1 8.9e-10 -0.81 0.02 0.98 FALSE
18 The Cancer Genome Atlas Thyroid Carcinoma HAUS6 0.07 0.11 blup 87 0.11 6.8e-11 5.8 -6.7 1.9e-11 -0.89 0.06 0.94 FALSE