Best TWAS P=6.81e-24 · Best GWAS P=3.89e-24 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | SYK | 0.49 | 0.22 | lasso | 7 | 0.29 | 4.8e-21 | 10 | -8.5 | 1.3e-17 | -0.85 | 0 | 1 | FALSE |
| 2 | GTEx | Testis | SYK | 0.29 | 0.30 | lasso | 2 | 0.30 | 1.3e-13 | 10 | -10.1 | 6.8e-24 | -0.99 | 0 | 1 | TRUE |
| 3 | NTR | Blood | SYK | 0.10 | 0.05 | bslmm | 603 | 0.07 | 2.4e-21 | 10 | -5.6 | 2.7e-08 | -0.75 | 0 | 1 | FALSE |
| 4 | YFS | Blood | SYK | 0.20 | 0.14 | bslmm | 594 | 0.15 | 1.5e-45 | 10 | -9.6 | 5.6e-22 | -0.87 | 0 | 1 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SYK | 0.09 | 0.07 | lasso | 5 | 0.06 | 3.8e-07 | 10 | -9.6 | 1.2e-21 | -0.98 | 0 | 1 | FALSE |