TWAS
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Traits
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Blood Platelet Count
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chr10:24,445,550-25,939,515
Best TWAS P=8.53e-27 · Best GWAS P=2.59e-24 conditioned to 0.248
24.4M
24.6M
24.8M
25M
25.2M
25.4M
25.6M
25.8M
26M
0
5
10
15
20
25
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells Transformed fibroblasts
PRTFDC1
0.24
0.03
lasso
4
0.02
0.011
-10
11
8.5e-27
-0.9
0.01
0.98
TRUE