Best TWAS P=1.07e-11 · Best GWAS P=8.03e-17 conditioned to 1.27e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | YME1L1 | 0.02 | 0.02 | lasso | 2 | 0.02 | 6.9e-07 | -6.8 | -6.8 | 1.1e-11 | 0.85 | 0.06 | 0.94 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | YME1L1 | 0.02 | 0.01 | blup | 65 | 0.02 | 4.4e-05 | -4.6 | 5.4 | 5.4e-08 | -0.76 | 0.38 | 0.45 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | MASTL | 0.19 | 0.17 | blup | 61 | 0.17 | 9.2e-10 | -3.5 | 5.2 | 1.7e-07 | -0.72 | 1.00 | 0.00 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | MASTL | 0.10 | 0.08 | blup | 61 | 0.09 | 2.0e-10 | -3.5 | 5.7 | 1.1e-08 | -0.83 | 0.72 | 0.28 | FALSE |