TWAS
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Traits
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Traits
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Blood Platelet Count
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chr10:26,699,872-28,142,838
Best TWAS P=1.07e-11 · Best GWAS P=8.03e-17 conditioned to 1.27e-06
26.8M
27M
27.2M
27.4M
27.6M
27.8M
28M
28.2M
0
5
10
15
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
NTR
Blood
YME1L1
0.02
0.02
lasso
2
0.02
6.9e-07
-6.8
-6.8
1.1e-11
0.85
0.06
0.94
TRUE
4
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
MASTL
0.10
0.08
blup
61
0.09
2.0e-10
-3.5
5.7
1.1e-08
-0.83
0.72
0.28
FALSE
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
YME1L1
0.02
0.01
blup
65
0.02
4.4e-05
-4.6
5.4
5.4e-08
-0.76
0.38
0.45
FALSE
3
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
MASTL
0.19
0.17
blup
61
0.17
9.2e-10
-3.5
5.2
1.7e-07
-0.72
1.00
0.00
FALSE