[Hub]/) : Traits : Blood Platelet Count :

chr1:117,451,498-119,169,364

Best TWAS P=8.21e-27 · Best GWAS P=1.21e-79 conditioned to 1.39e-20

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex GDAP2 0.06 0.01 blup 407 0.04 2.5e-05 -4.8 6.0 2.1e-09 0.29 0.54 0.06 FALSE
2 GTEx Colon Transverse GDAP2 0.19 -0.01 enet 40 0.00 3.4e-01 8.8 7.7 1.4e-14 0.42 0.04 0.40 TRUE
3 GTEx Heart Left Ventricle FAM46C 0.25 0.14 lasso 4 0.17 1.9e-09 -6.4 7.1 1.3e-12 0.18 1.00 0.00 FALSE
4 GTEx Thyroid GDAP2 0.09 0.04 lasso 6 0.02 2.0e-02 -4.8 -6.8 7.5e-12 -0.26 0.33 0.03 FALSE
5 ROSMAP Brain Pre-frontal Cortex FAM46C 0.04 0.00 bslmm 409 0.01 4.1e-02 -11.6 -9.5 2.5e-21 -0.39 0.04 0.38 TRUE
6 YFS Blood FAM46C 0.04 0.01 bslmm 394 0.01 6.8e-04 11.0 -8.5 1.6e-17 -0.50 0.13 0.45 TRUE
7 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma FAM46C 0.12 0.00 blup 77 0.05 1.6e-03 10.3 -10.7 8.2e-27 -0.55 0.02 0.23 TRUE