Best TWAS P=6.86e-21 · Best GWAS P=4.68e-19 conditioned to 0.0665
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Not Sun Exposed Suprapubic | PICALM | 0.10 | 0.02 | enet | 9 | 0.01 | 5.5e-02 | 7.2 | 7.2 | 7.2e-13 | -0.31 | 0.06 | 0.80 | FALSE |
| 2 | NTR | Blood | PICALM | 0.02 | 0.01 | blup | 501 | 0.01 | 3.2e-05 | 6.4 | 7.8 | 4.1e-15 | -0.47 | 0.91 | 0.06 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | PICALM | 0.04 | 0.01 | blup | 87 | 0.02 | 1.9e-03 | -5.5 | -9.4 | 6.9e-21 | 0.85 | 0.03 | 0.82 | TRUE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | PICALM | 0.05 | 0.00 | blup | 87 | 0.01 | 5.0e-02 | 2.6 | -6.5 | 5.7e-11 | 0.61 | 0.02 | 0.31 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CCDC83 | 0.06 | 0.00 | blup | 79 | 0.03 | 4.0e-04 | 4.4 | 7.8 | 4.5e-15 | -0.47 | 0.01 | 0.36 | FALSE |