TWAS
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Traits
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Traits
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Blood Platelet Count
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chr11:84,971,275-86,479,920
Best TWAS P=6.86e-21 · Best GWAS P=4.68e-19 conditioned to 0.0665
85M
85.2M
85.4M
85.6M
85.8M
86M
86.2M
86.4M
0
5
10
15
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Brain Lower Grade Glioma
PICALM
0.04
0.01
blup
87
0.02
1.9e-03
-5.5
-9.4
6.9e-21
0.85
0.03
0.82
TRUE
2
NTR
Blood
PICALM
0.02
0.01
blup
501
0.01
3.2e-05
6.4
7.8
4.1e-15
-0.47
0.91
0.06
FALSE
5
The Cancer Genome Atlas
Prostate Adenocarcinoma
CCDC83
0.06
0.00
blup
79
0.03
4.0e-04
4.4
7.8
4.5e-15
-0.47
0.01
0.36
FALSE
1
GTEx
Skin Not Sun Exposed Suprapubic
PICALM
0.10
0.02
enet
9
0.01
5.5e-02
7.2
7.2
7.2e-13
-0.31
0.06
0.80
FALSE
4
The Cancer Genome Atlas
Lung Adenocarcinoma
PICALM
0.05
0.00
blup
87
0.01
5.0e-02
2.6
-6.5
5.7e-11
0.61
0.02
0.31
FALSE