Best TWAS P=1.11e-21 · Best GWAS P=8.54e-20 conditioned to 0.03
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ENDOD1 | 0.08 | 0.02 | enet | 20 | 0.06 | 8.4e-08 | -9.1 | 7.7 | 1.3e-14 | -0.66 | 0.00 | 1.00 | FALSE |
| 2 | NTR | Blood | ENDOD1 | 0.02 | 0.01 | lasso | 5 | 0.01 | 1.4e-03 | 4.5 | 6.2 | 6.1e-10 | -0.59 | 0.14 | 0.81 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | ENDOD1 | 0.20 | 0.08 | enet | 10 | 0.14 | 2.6e-17 | -6.6 | 7.0 | 2.8e-12 | -0.68 | 0.01 | 0.99 | FALSE |
| 4 | YFS | Blood | ENDOD1 | 0.09 | 0.05 | enet | 28 | 0.06 | 1.1e-19 | -9.0 | 9.6 | 1.1e-21 | -0.82 | 0.00 | 1.00 | TRUE |