Best TWAS P=1.09e-12 · Best GWAS P=7.84e-13 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | USP15 | 0.36 | 0.38 | lasso | 3 | 0.39 | 1.2e-22 | -7.1 | -7.1 | 1.1e-12 | 0.99 | 0.01 | 0.99 | TRUE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | MON2 | 0.02 | 0.02 | lasso | 3 | 0.01 | 1.5e-03 | 5.5 | -5.5 | 4.6e-08 | 0.24 | 0.47 | 0.06 | FALSE |