TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Blood Platelet Count
:
←
→
chr12:61,957,419-63,506,862
Best TWAS P=1.09e-12 · Best GWAS P=7.84e-13 conditioned to 1
62M
62.2M
62.4M
62.6M
62.8M
63M
63.2M
63.4M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Artery Aorta
USP15
0.36
0.38
lasso
3
0.39
1.2e-22
-7.1
-7.1
1.1e-12
0.99
0.01
0.99
TRUE
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
MON2
0.02
0.02
lasso
3
0.01
1.5e-03
5.5
-5.5
4.6e-08
0.24
0.47
0.06
FALSE