[Hub]/) : Traits : Blood Platelet Count :

chr12:93,110,493-94,589,220

Best TWAS P=6.49e-30 · Best GWAS P=1.23e-28 conditioned to 0.02

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Colon Transverse UBE2N 0.16 0.00 lasso 4 0.01 1.0e-01 1.63 -6.8 7.8e-12 -0.70 0.02 0.78 FALSE
2 GTEx Muscle Skeletal MRPL42 0.07 0.02 lasso 3 0.04 1.5e-04 8.71 7.0 3.0e-12 0.37 0.69 0.02 FALSE
3 GTEx Testis MRPL42 0.35 0.17 lasso 3 0.24 3.3e-11 10.87 11.2 5.1e-29 0.87 0.00 1.00 FALSE
4 YFS Blood MRPL42 0.06 0.03 lasso 6 0.04 1.7e-14 11.10 10.1 3.7e-24 0.87 0.00 1.00 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma MRPL42 0.05 0.03 blup 49 0.04 3.9e-08 10.78 -8.6 7.8e-18 -0.76 0.01 0.98 FALSE
6 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MRPL42 0.16 0.06 lasso 4 0.10 5.2e-11 10.87 -7.1 1.2e-12 -0.79 0.01 0.99 FALSE
7 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma MRPL42 0.13 0.01 blup 49 0.02 1.4e-02 0.26 -6.0 2.1e-09 -0.71 0.01 0.78 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma MRPL42 0.09 0.04 enet 10 0.06 5.9e-07 0.26 -5.4 8.6e-08 -0.51 0.11 0.54 FALSE
9 The Cancer Genome Atlas Lung Squamous Cell Carcinoma MRPL42 0.05 0.02 blup 49 0.03 5.1e-04 -4.69 -8.3 6.9e-17 -0.53 0.06 0.24 FALSE
10 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma MRPL42 0.11 0.06 lasso 2 0.09 7.1e-07 5.41 -8.7 3.7e-18 -0.74 0.04 0.95 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma MRPL42 0.07 0.03 blup 49 0.03 1.4e-04 11.10 -11.4 6.5e-30 -0.87 0.00 1.00 TRUE
12 The Cancer Genome Atlas Stomach Adenocarcinoma MRPL42 0.12 0.01 blup 49 0.04 4.0e-04 11.10 -9.6 8.5e-22 -0.71 0.00 0.79 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma MRPL42 0.09 0.00 enet 8 0.03 9.4e-04 10.78 -7.0 3.8e-12 -0.68 0.00 0.88 FALSE