Best TWAS P=1.03e-15 · Best GWAS P=8.14e-17 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | FGD6 | 0.19 | 0.19 | lasso | 6 | 0.19 | 6.2e-11 | 2.4 | -5.8 | 8.3e-09 | -0.56 | 0.66 | 0.34 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | FGD6 | 0.19 | 0.22 | lasso | 5 | 0.20 | 2.4e-15 | 8.2 | -8.0 | 1.0e-15 | -0.95 | 0.01 | 0.99 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | NDUFA12 | 0.02 | 0.01 | blup | 93 | 0.01 | 2.2e-02 | 3.0 | 6.0 | 2.3e-09 | 0.51 | 0.04 | 0.18 | FALSE |
| 4 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | NDUFA12 | 0.08 | 0.00 | blup | 93 | 0.04 | 1.0e-03 | -1.3 | 5.4 | 8.4e-08 | 0.40 | 0.01 | 0.28 | FALSE |