[Hub]/) : Traits : Blood Platelet Count : ← →

chr12:132,369,172-133,778,796

Best TWAS P=7.7e-10 · Best GWAS P=4.22e-06 conditioned to 0.00589

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts ANKLE2 0.39 0.39 enet 19 0.44 1.9e-36 -4.0 -5.2 2.2e-07 0.33 0.09 0.68 FALSE
2 GTEx Colon Sigmoid ZNF605 0.14 -0.01 lasso 4 0.01 1.8e-01 -4.0 -5.2 2.7e-07 0.09 0.01 0.17 FALSE
3 GTEx Esophagus Gastroesophageal Junction ZNF605 0.27 0.03 lasso 13 0.10 1.8e-04 -3.1 -5.3 1.3e-07 0.37 0.06 0.47 FALSE
4 GTEx Thyroid ZNF605 0.16 0.03 enet 29 0.07 7.4e-06 -4.3 -6.1 1.2e-09 0.43 0.05 0.80 FALSE
5 GTEx Whole Blood PGAM5 0.07 0.01 enet 20 0.04 2.9e-04 -4.2 -5.3 9.2e-08 0.13 0.01 0.27 FALSE
6 METSIM Adipose FBRSL1 0.09 0.01 blup 286 0.03 1.7e-05 -4.4 -5.4 6.3e-08 0.69 0.01 0.90 FALSE
7 NTR Blood ZNF605 0.03 0.04 blup 211 0.04 1.8e-12 4.2 -6.2 7.7e-10 0.32 0.05 0.82 TRUE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ANKLE2 0.15 0.05 enet 12 0.06 1.6e-07 -4.0 -5.2 1.7e-07 0.16 0.01 0.69 FALSE