[Hub]/) : Traits : Blood Platelet Count :

chr13:32,171,381-34,332,027

Best TWAS P=1.57e-36 · Best GWAS P=2.59e-36 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RP11-298P3.4 0.09 0.01 lasso 7 0.00 1.9e-01 8.50 9.2 2.3e-20 0.84 0.07 0.84 FALSE
2 GTEx Artery Aorta N4BP2L2 0.13 0.10 lasso 3 0.09 1.1e-05 12.47 12.4 4.1e-35 0.97 0.02 0.98 FALSE
3 GTEx Nerve Tibial RP11-298P3.4 0.06 0.01 enet 19 0.01 7.8e-02 8.90 7.1 1.0e-12 0.66 0.12 0.56 FALSE
4 GTEx Whole Blood KL 0.12 0.00 lasso 7 0.00 4.9e-01 0.25 -7.4 1.6e-13 -0.58 0.13 0.12 FALSE
5 YFS Blood KL 0.05 0.01 blup 522 0.04 7.6e-13 8.44 -5.2 2.2e-07 -0.50 0.13 0.87 FALSE
6 YFS Blood PDS5B 0.03 0.04 lasso 1 0.03 1.4e-11 8.74 8.7 2.4e-18 0.82 0.37 0.63 FALSE
7 The Cancer Genome Atlas Bladder Urothelial Carcinoma CG030 0.06 0.01 blup 38 0.03 6.0e-04 -9.01 -11.0 5.2e-28 -0.83 0.02 0.77 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma CG030 0.04 0.01 lasso 3 0.02 2.1e-04 12.47 -12.4 2.5e-35 -0.97 0.00 1.00 FALSE
9 The Cancer Genome Atlas Breast Invasive Carcinoma N4BP2L2 0.02 0.02 lasso 2 0.01 1.4e-03 12.58 12.6 1.6e-36 1.00 0.00 0.97 TRUE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CG030 0.07 0.02 lasso 4 0.03 2.4e-04 12.15 -10.4 2.4e-25 -0.83 0.01 0.62 FALSE
11 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma N4BP2L2 0.04 0.03 blup 69 0.02 9.4e-04 12.47 11.9 2.0e-32 0.96 0.01 0.98 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma CG030 0.06 0.01 blup 38 0.02 1.9e-03 -8.34 -10.4 2.6e-25 -0.82 0.03 0.82 FALSE
13 The Cancer Genome Atlas Brain Lower Grade Glioma N4BP2L2 0.10 0.10 lasso 4 0.11 5.2e-12 12.47 12.5 1.3e-35 0.97 0.01 0.99 FALSE
14 The Cancer Genome Atlas Lung Adenocarcinoma N4BP2L2 0.03 0.02 lasso 4 0.02 2.8e-03 12.56 12.1 1.3e-33 0.89 0.01 0.96 FALSE
15 The Cancer Genome Atlas Lung Squamous Cell Carcinoma N4BP2L2 0.04 0.04 lasso 2 0.03 1.5e-04 12.58 12.3 9.9e-35 0.99 0.00 0.99 FALSE
16 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma CG030 0.08 0.04 blup 38 0.04 1.4e-03 12.15 -11.3 1.6e-29 -0.92 0.00 0.92 FALSE
17 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CG030 0.12 0.02 blup 38 0.03 3.1e-02 11.52 -9.1 7.2e-20 -0.81 0.00 0.60 FALSE
18 The Cancer Genome Atlas Prostate Adenocarcinoma N4BP2L2 0.06 0.03 lasso 3 0.05 1.0e-05 -4.96 8.4 4.8e-17 0.79 0.03 0.96 FALSE
19 The Cancer Genome Atlas Thyroid Carcinoma EEF1DP3 0.05 0.00 blup 99 0.01 7.1e-02 -1.79 -5.1 3.0e-07 0.03 0.02 0.14 TRUE
20 The Cancer Genome Atlas Thyroid Carcinoma N4BP2L2 0.12 0.14 enet 7 0.16 1.1e-15 11.59 12.3 6.9e-35 0.98 0.01 0.99 FALSE
21 The Cancer Genome Atlas Thyroid Carcinoma PDS5B 0.02 0.01 blup 78 0.02 1.2e-02 12.30 -11.0 2.2e-28 -0.93 0.02 0.78 FALSE