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chr13:32,171,381-34,332,027

Best TWAS P=1.57e-36 · Best GWAS P=2.59e-36 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
9	The Cancer Genome Atlas	Breast Invasive Carcinoma	N4BP2L2	0.02	0.02	lasso	2	0.01	1.4e-03	12.58	12.6	1.6e-36	1.00	0.00	0.97	TRUE
19	The Cancer Genome Atlas	Thyroid Carcinoma	EEF1DP3	0.05	0.00	blup	99	0.01	7.1e-02	-1.79	-5.1	3.0e-07	0.03	0.02	0.14	TRUE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	N4BP2L2	0.10	0.10	lasso	4	0.11	5.2e-12	12.47	12.5	1.3e-35	0.97	0.01	0.99	FALSE
8	The Cancer Genome Atlas	Breast Invasive Carcinoma	CG030	0.04	0.01	lasso	3	0.02	2.1e-04	12.47	-12.4	2.5e-35	-0.97	0.00	1.00	FALSE
2	GTEx	Artery Aorta	N4BP2L2	0.13	0.10	lasso	3	0.09	1.1e-05	12.47	12.4	4.1e-35	0.97	0.02	0.98	FALSE
20	The Cancer Genome Atlas	Thyroid Carcinoma	N4BP2L2	0.12	0.14	enet	7	0.16	1.1e-15	11.59	12.3	6.9e-35	0.98	0.01	0.99	FALSE
15	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	N4BP2L2	0.04	0.04	lasso	2	0.03	1.5e-04	12.58	12.3	9.9e-35	0.99	0.00	0.99	FALSE
14	The Cancer Genome Atlas	Lung Adenocarcinoma	N4BP2L2	0.03	0.02	lasso	4	0.02	2.8e-03	12.56	12.1	1.3e-33	0.89	0.01	0.96	FALSE
11	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	N4BP2L2	0.04	0.03	blup	69	0.02	9.4e-04	12.47	11.9	2.0e-32	0.96	0.01	0.98	FALSE
16	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	CG030	0.08	0.04	blup	38	0.04	1.4e-03	12.15	-11.3	1.6e-29	-0.92	0.00	0.92	FALSE
21	The Cancer Genome Atlas	Thyroid Carcinoma	PDS5B	0.02	0.01	blup	78	0.02	1.2e-02	12.30	-11.0	2.2e-28	-0.93	0.02	0.78	FALSE
7	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	CG030	0.06	0.01	blup	38	0.03	6.0e-04	-9.01	-11.0	5.2e-28	-0.83	0.02	0.77	FALSE
10	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CG030	0.07	0.02	lasso	4	0.03	2.4e-04	12.15	-10.4	2.4e-25	-0.83	0.01	0.62	FALSE
12	The Cancer Genome Atlas	Brain Lower Grade Glioma	CG030	0.06	0.01	blup	38	0.02	1.9e-03	-8.34	-10.4	2.6e-25	-0.82	0.03	0.82	FALSE
1	GTEx	Adipose Subcutaneous	RP11-298P3.4	0.09	0.01	lasso	7	0.00	1.9e-01	8.50	9.2	2.3e-20	0.84	0.07	0.84	FALSE
17	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CG030	0.12	0.02	blup	38	0.03	3.1e-02	11.52	-9.1	7.2e-20	-0.81	0.00	0.60	FALSE
6	YFS	Blood	PDS5B	0.03	0.04	lasso	1	0.03	1.4e-11	8.74	8.7	2.4e-18	0.82	0.37	0.63	FALSE
18	The Cancer Genome Atlas	Prostate Adenocarcinoma	N4BP2L2	0.06	0.03	lasso	3	0.05	1.0e-05	-4.96	8.4	4.8e-17	0.79	0.03	0.96	FALSE
4	GTEx	Whole Blood	KL	0.12	0.00	lasso	7	0.00	4.9e-01	0.25	-7.4	1.6e-13	-0.58	0.13	0.12	FALSE
3	GTEx	Nerve Tibial	RP11-298P3.4	0.06	0.01	enet	19	0.01	7.8e-02	8.90	7.1	1.0e-12	0.66	0.12	0.56	FALSE
5	YFS	Blood	KL	0.05	0.01	blup	522	0.04	7.6e-13	8.44	-5.2	2.2e-07	-0.50	0.13	0.87	FALSE