Hub : Genes

PGAM5

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cerebellar Hemisphere	0.3250	0.1140	0.00087	-0.001	NA	-0.008	NA	0.024	0.34000	NA	5.8e-01	NA	8.2e-02
2	GTEx	Lung	0.0886	0.0349	0.00100	0.006	NA	0.000	NA	0.002	0.09800	NA	2.9e-01	NA	2.1e-01
3	GTEx	Muscle Skeletal	0.0940	0.0376	0.00034	0.000	NA	0.008	NA	0.010	0.32000	NA	5.2e-02	NA	3.5e-02
4	GTEx	Nerve Tibial	0.1964	0.0597	0.00033	0.040	NA	0.065	NA	0.062	0.00081	NA	2.4e-05	NA	3.6e-05
5	GTEx	Stomach	0.1600	0.0690	0.00400	0.007	NA	0.048	NA	0.017	0.14000	NA	2.5e-03	NA	4.8e-02
6	GTEx	Whole Blood	0.0670	0.0330	0.00660	0.006	NA	0.036	NA	0.003	0.08900	NA	2.9e-04	NA	1.5e-01
7	TCGA	Lung Squamous Cell Carcinoma	0.0298	0.0173	0.00350	-0.001	0.017	0.007	NA	0.001	0.50000	0.0046	4.5e-02	NA	2.1e-01
8	TCGA	Thyroid Carcinoma	0.0690	0.0360	0.00480	-0.002	0.022	0.013	NA	0.005	0.53000	0.0030	1.9e-02	NA	1.0e-01

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.6	1.0	2.8	0.7	1.7	0.3	1.6	0.0	0.0	-1.2	-0.8
Bipolar Disorder or Schizophrenia	0.3	0.7	2.7	1.6	0.6	-0.1	1.4	0.0	0.0	-0.1	-0.6
Depressed Affect (Nagel 2018)	0.3	0.7	3.1	-0.9	-0.6	-0.3	-0.0	0.6	-1.8	0.8	-0.5
Depression (Nagel 2018)	1.2	1.9	4.2	-1.4	-1.6	-0.3	1.2	-1.1	-2.0	0.4	-1.7
Intelligence (Savage-Jansen 2018)	0.7	2.3	11.0	0.4	0.7	1.2	0.9	3.3	-0.1	-1.4	1.6
Neuroticism (Nagel 2018)	0.2	0.6	2.5	-0.7	-0.6	0.1	0.8	-0.1	-1.6	0.5	-0.6
Schizophrenia (2018)	0.2	0.5	2.2	1.5	-0.6	-0.3	0.6	0.0	0.0	0.9	-0.1
Schizophrenia vs Biploar Disorder	0.5	0.6	2.2	1.5	-0.1	0.9	1.1	0.0	0.0	-0.0	-0.8
Worry (Nagel 2018)	0.4	0.9	2.0	-0.8	-1.0	0.5	1.2	-1.0	-1.4	0.4	-0.7
Alzheimer’s Disease (in mother)	0.7	0.8	3.1	0.0	-0.3	0.2	0.4	-1.8	1.4	-0.6	-0.7
Alzheimer’s Disease (in father)	0.5	0.5	1.8	-0.5	0.4	-0.5	-1.3	-0.5	0.1	1.3	-0.2
Alzheimer’s Disease (including proxy)	0.5	0.7	2.8	-0.5	-0.4	-0.1	-0.1	-1.7	1.0	0.1	-1.2
Crohns Disease (2017)	0.4	0.8	1.9	-1.1	0.1	-0.4	-1.4	-0.8	0.2	1.2	1.0
Irritable Bowel Disease (IBD)	0.4	1.0	4.5	-0.3	0.5	1.2	-1.0	-0.7	0.0	0.2	2.1
Ulcerative Colitis (UC)	0.8	1.5	5.2	0.7	1.0	2.3	-0.0	-0.1	0.3	-1.1	2.0
Major Depression (MDD)	0.1	0.1	0.5	0.1	0.1	0.5	0.7	0.0	0.0	-0.3	-0.4
Reaction Time	0.9	1.7	4.3	-0.2	0.3	-0.2	-2.1	-0.9	-0.9	1.9	1.9
Verbal and Numeric Reasoning (VNR)	0.9	2.1	7.0	1.0	1.3	1.2	0.9	2.6	0.2	-1.6	1.4
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ovarian Cancer	2.2	2.9	10.5	2.1	-2.1	-0.8	0.4	1.1	-0.8	0.7	-3.2
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	1.9	2.8	10.9	0.4	3.3	1.8	1.0	1.0	0.5	-1.8	1.5
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	1.3	1.7	3.7	-0.3	-1.4	-1.9	-1.1	0.2	-1.2	1.4	-1.9
Coronary Artery Disease (CAD)	0.2	0.2	0.4	0.6	-0.6	0.6	-0.0	0.0	0.0	-0.6	-0.2
Crohns Disease (2012)	0.1	0.2	1.3	-1.1	0.2	0.1	0.5	0.0	0.0	-0.2	0.2
Mean Putamen Volume	0.6	0.7	3.1	0.5	0.9	1.0	0.2	0.5	1.8	-0.5	0.2
Fasting Glucose	1.8	2.1	5.9	-2.4	-0.7	-1.6	-1.2	-1.5	1.5	1.3	-0.7
HbA1C	0.8	0.9	3.0	-1.5	0.9	-0.3	-1.0	0.1	-0.3	0.5	1.7
HDL Cholesterol	0.2	0.4	1.4	-0.2	-0.3	0.3	-0.6	0.9	-0.0	0.5	1.2
LDL Cholesterol	0.4	0.6	1.6	0.3	1.1	0.8	0.0	0.0	1.3	-1.1	-0.7
Lupus	0.4	0.6	2.7	-0.3	0.7	0.6	1.6	-0.1	0.3	-0.8	-0.5
Neuroticism (2016)	0.1	0.2	0.3	-0.4	-0.4	0.6	0.2	0.4	-0.3	-0.2	-0.5
Primary Biliary Cirrhosis	1.1	1.5	6.5	-0.4	2.0	-0.5	-0.9	-2.5	-0.1	-0.3	0.7
Rheumatoid Arthritis	0.2	0.2	0.7	0.2	0.9	-0.0	-0.3	-0.7	0.1	-0.1	0.5
Schizophrenia (2014)	0.4	0.8	3.7	1.5	-0.0	0.1	1.9	0.0	0.0	0.0	-0.8
Triglycerides	0.1	0.2	0.8	-0.9	0.2	-0.6	-0.7	0.0	-0.1	0.4	0.4
Type 2 Diabetes (T2D) (2012)	0.2	0.3	1.2	-0.3	0.5	-0.2	0.2	0.0	0.0	-0.6	-1.1
Ulcerative Colitis	0.7	1.0	3.6	0.9	0.1	1.9	0.2	0.0	0.0	-1.2	1.3
Blood Eosinophil Count	0.5	4.1	13.8	-0.1	3.7	1.9	0.9	1.9	0.8	-3.0	1.3
Blood Platelet Count	1.3	15.1	28.5	-4.3	-3.9	-3.1	-3.0	-4.8	-5.3	3.8	1.6
Blood Red Count	0.2	2.1	5.5	-1.3	-0.3	-1.3	-1.2	-1.4	-1.0	1.8	2.3
Blood White Count	0.1	0.5	2.3	0.5	-1.5	0.2	-0.5	0.0	-0.3	0.4	-1.1
Heel T-Score	0.3	2.6	6.8	1.1	0.0	1.9	1.7	-0.0	2.6	-2.1	-1.4
BMI	0.8	4.8	21.8	2.4	-2.5	-0.5	0.3	2.0	-0.0	0.3	-4.7
Height	0.5	10.3	45.8	0.1	1.0	1.9	3.2	6.8	0.9	-3.2	-3.2
Waist Hip Ratio (WHR)	0.5	2.0	9.3	-3.0	-0.2	-0.8	-1.2	1.6	-0.4	0.2	1.4
Systolic Blood Pressure	0.8	3.9	14.9	-0.6	3.9	2.7	1.3	0.2	1.3	-2.0	1.2
Smoking Status	0.7	1.7	9.0	-0.6	1.7	1.2	0.1	3.0	-0.6	-0.1	0.1
Allergy or Eczema	1.9	5.0	8.8	3.0	2.6	2.7	1.5	2.6	0.9	-2.3	1.3
Cardiovascular Disease	0.2	0.6	2.6	-0.1	0.8	0.3	0.1	0.9	1.6	0.0	-1.0
Hypothyroidism (self reported)	0.3	0.6	1.8	0.4	1.3	0.7	0.6	0.8	-0.5	-1.1	-0.2
Respiratory disease	0.9	2.0	7.0	-0.4	2.6	1.0	-0.3	2.1	0.2	-0.9	1.5
Type 2 Diabetes (T2D) (2018)	1.0	1.9	9.4	0.9	-3.1	-0.3	-0.6	-0.9	0.6	0.6	-1.8
Lung FEV1/FVC ratio	0.8	3.9	9.8	1.8	-0.4	1.8	2.5	-0.3	1.8	-3.1	-2.2
Lung FVC	0.9	4.3	8.2	-2.9	-1.0	-1.8	-2.3	-1.3	-2.5	2.3	2.0
Neuroticism	0.4	1.0	3.1	-0.6	-1.2	0.5	1.4	0.1	-1.0	0.3	-1.8
Chronotype (morning person)	0.2	0.5	2.8	0.3	0.5	0.2	-0.4	-0.2	1.7	-0.7	0.5
Hair Pigment	0.0	1.2	5.9	0.6	-0.2	0.8	0.8	2.4	-1.2	-0.6	-0.3
Tanning	0.1	0.7	1.8	-0.6	-0.9	-0.5	-0.7	-1.3	0.7	1.3	-0.4
Hand grip strength (left)	1.3	3.5	11.1	-3.3	-1.3	-1.1	-2.7	0.9	-0.1	2.2	1.0
Number of treatments/medications taken	0.3	0.5	1.8	-1.3	0.6	-0.7	0.3	0.6	0.4	0.1	-0.9
Average weekly spirits intake	1.0	1.3	3.1	0.9	1.8	0.9	0.6	0.5	1.5	-1.6	0.3
Sensitivity / hurt feelings	1.2	2.1	6.6	2.0	0.6	1.8	0.7	2.6	-0.3	-1.1	-1.0
Frequency of depressed mood in last 2 weeks	1.6	2.3	6.3	-1.8	-1.7	-1.1	0.2	-1.2	-2.5	1.4	-1.0
Hearing difficulty/problems: Yes	0.5	0.8	3.8	0.3	-0.2	0.6	0.9	1.9	-0.9	-0.8	-0.1
Relative age of first facial hair	0.4	0.9	3.6	-0.6	0.7	0.5	0.3	1.9	0.4	-1.5	-0.5
Other serious medical condition/disability diagnosed by doctor	2.7	3.5	10.5	0.7	3.2	1.9	1.9	0.8	0.8	-2.9	-0.4
Ever used hormone-replacement therapy (HRT)	1.0	1.2	4.3	-1.2	-0.7	-1.2	-0.4	1.1	-2.1	0.9	-0.2
Ever had hysterectomy (womb removed)	0.2	0.2	0.7	0.9	0.6	-0.0	-0.3	0.3	0.1	0.2	0.2
Systolic blood pressure, automated reading	1.4	4.1	9.9	-0.1	3.1	2.6	2.5	-0.5	1.8	-2.4	-0.5
Eye problems/disorders: Diabetes related eye disease	1.2	1.3	4.1	1.1	-1.5	-0.6	0.9	-0.4	1.1	-0.2	-2.0
Angina	0.7	0.9	3.4	0.4	-1.9	0.1	-0.2	0.3	0.5	0.6	-1.8
Medication for hormone replacement therapy	1.8	2.0	8.1	0.7	-0.9	-1.2	-1.2	1.3	-2.8	1.5	0.4
Vitamin and mineral supplements	0.4	0.6	1.6	-1.0	-0.7	-1.2	-0.1	0.4	-0.3	0.4	-1.1
Supplements: Zinc	4.0	4.3	12.9	3.6	1.3	2.0	1.8	1.5	0.6	-2.6	-1.9
Medication: Co-codamol	0.9	1.0	3.9	-0.3	-0.7	-0.0	0.3	2.0	1.1	0.1	-1.5
Medication: Metformin	1.4	1.9	7.6	1.3	-2.1	-0.6	0.1	0.6	0.8	-0.3	-2.8
Diabetes (father)	0.2	0.3	0.7	-0.3	-0.8	0.1	0.3	0.0	0.7	-0.7	-0.8
Diabetes (mother)	1.2	1.6	4.9	1.0	-0.7	0.6	1.7	-0.6	2.2	-1.0	-1.4
Severe depression (siblings)	0.5	0.6	2.4	-0.4	0.4	0.1	0.9	-0.9	-0.2	-1.5	0.0
Pack years adult smoking proportion	0.2	0.3	1.7	0.3	-0.3	1.3	-0.2	0.4	0.2	-0.8	0.3
Impedance of leg (right)	0.6	2.9	8.8	-2.8	1.5	-0.7	0.1	-1.9	-0.7	-0.4	3.0
Leg fat-free mass (left)	1.0	5.3	15.3	2.6	-2.1	0.1	0.6	3.9	1.1	0.2	-3.8
Trunk fat percentage	0.3	1.3	4.2	-0.1	-0.1	-0.8	1.1	2.1	-0.6	-0.7	-1.8
Hand grip strength (right)	1.3	3.5	10.6	-3.3	-1.2	-1.0	-2.8	0.5	-0.2	2.4	1.1
Townsend deprivation index at recruitment	0.2	0.2	0.6	0.1	0.7	0.4	-0.3	0.8	0.5	0.2	0.2
Current tobacco smoking	0.6	1.0	3.6	-0.5	0.0	1.5	-0.2	1.9	-1.0	0.1	-0.9
Average weekly fortified wine intake	1.4	1.6	3.0	-1.4	1.7	0.8	1.4	-0.2	1.7	-1.3	0.7
Maternal smoking around birth	0.4	0.6	2.5	-0.8	0.0	-0.9	-0.6	1.6	-0.2	0.2	-0.5
Fed-up feelings	0.5	0.9	4.6	-0.3	-0.7	-0.5	1.0	0.4	-0.6	0.0	-2.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	2.2	-1.1	-1.5	-0.5	0.5	0.9	-0.9	0.7	-1.1
Relative age voice broke	0.7	1.1	2.4	-1.5	1.4	-0.2	0.1	1.6	-1.1	-0.9	-0.1
Taking other prescription medications	0.4	0.6	2.4	-0.9	1.6	-0.8	0.5	0.4	0.2	0.3	-0.4
Age when periods started (menarche)	2.1	5.1	13.2	-0.3	3.6	2.6	1.5	2.1	1.0	-3.4	1.2
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	2.9	1.7	0.5	-0.4	-0.5	1.3	0.5	-0.1	1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.1	0.3	0.4	0.4	-0.1	-0.5	0.4	-0.2	0.2	-0.3
Tinnitus: Yes, but not now, but have in the past	0.4	0.5	1.2	-1.0	-0.7	0.4	-0.2	-0.2	0.7	0.7	1.1
Qualifications: CSEs or equivalent	2.8	3.7	10.0	-0.7	-0.2	-2.4	-3.2	0.8	-1.9	2.4	1.7
Serious illness, injury or assault to yourself	1.1	1.3	4.0	1.1	1.4	0.1	0.7	2.0	1.2	-0.8	-0.8
High blood pressure	0.5	1.3	3.1	-1.2	1.1	0.4	0.7	1.8	1.2	-0.4	-1.5
Hayfever, allergic rhinitis or eczema	1.8	3.8	8.8	3.0	1.9	2.4	1.1	2.5	0.6	-1.9	1.0
Multivitamins +/- minerals	0.9	1.2	2.7	1.3	1.2	1.7	0.2	-1.3	-0.5	-1.2	0.4
Stomach or abdominal pain in last month	2.6	3.2	6.7	-1.8	-1.7	-2.1	-2.2	-1.0	-1.4	2.6	0.9
Supplements: Glucosamine	0.4	0.5	2.4	-1.5	0.3	-0.5	-0.1	-0.8	0.4	0.2	0.8
Diverticular disease/diverticulitis (self-reported)	0.8	0.9	2.8	-1.3	1.0	-0.4	-0.3	-1.7	-1.2	0.3	0.3
Medication: Atenolol	1.1	1.4	3.7	-1.9	-0.2	-0.6	-1.8	-0.9	-0.0	1.2	1.3
Medication: Levothyroxine sodium	0.9	1.4	3.9	0.1	0.9	1.2	1.3	1.0	-0.9	-2.0	-1.4
Sitting height	0.2	1.3	3.3	1.7	-0.0	1.0	0.0	1.8	1.7	-0.6	0.5
Chronic bronchitis/emphysema (father)	0.3	0.3	0.8	-0.6	0.0	-0.2	-0.3	0.7	-0.8	0.3	0.9
High blood pressure (mother)	0.3	0.4	2.2	0.4	-0.6	-0.5	-0.1	-0.4	0.4	0.4	-1.5
Body mass index (BMI)	0.8	3.3	12.3	0.5	-2.5	-1.9	-0.1	1.4	-0.4	1.3	-3.5
Impedance of leg (left)	0.9	4.3	16.0	-2.8	1.4	-0.8	-0.8	-2.5	-0.9	-0.1	4.0
Leg predicted mass (left)	1.0	5.3	14.9	2.6	-2.1	0.1	0.7	3.9	1.2	0.2	-3.8
Trunk fat mass	0.6	2.4	8.9	0.4	-1.1	-0.9	1.1	2.6	-0.0	-0.3	-3.0
Waist circumference	1.1	4.0	14.6	0.2	-2.2	-1.7	0.1	2.9	0.1	0.8	-3.8
Number of incorrect matches in round	0.5	0.8	2.6	1.6	-0.4	1.2	-0.4	0.5	-0.2	0.2	-1.2
Past tobacco smoking	0.9	1.6	9.9	-0.3	0.0	-0.4	-0.7	-3.1	0.7	-0.1	1.3
Alcohol usually taken with meals	0.2	0.3	1.2	-0.1	0.2	0.3	-0.6	-0.6	0.2	-0.3	1.1
Nervous feelings	0.3	0.6	2.0	-0.7	1.1	0.5	1.4	0.5	-0.4	-0.6	-0.1
Frequency of tenseness / restlessness in last 2 weeks	1.5	2.3	4.6	-2.0	-2.1	-1.1	-0.3	-1.8	-1.3	1.4	-1.3
Hearing difficulty/problems with background noise	0.6	1.0	2.2	0.6	-1.4	-0.3	1.1	1.5	-0.5	0.3	-1.5
Hair/balding pattern: Pattern 2	0.6	0.8	3.3	-1.8	0.0	0.3	-1.0	-0.7	-0.8	0.6	0.5
Had menopause	1.4	1.7	5.5	0.2	1.8	0.3	2.3	0.2	0.4	-2.0	-1.1
Had other major operations	2.8	3.4	8.7	2.2	-0.9	-0.5	1.5	1.2	3.0	-0.7	-2.9
Forced vital capacity (FVC)	0.4	1.5	3.4	-0.9	-0.3	-0.9	-1.4	1.0	-1.1	1.9	1.7
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.6	1.7	1.2	1.0	1.3	-0.0	0.5	0.3	-0.5	-0.1
Ever unenthusiastic/disinterested for a whole week	1.1	1.3	5.6	-0.0	0.5	2.0	-0.4	0.2	-0.1	-0.3	2.4
Qualifications: None of the above	0.5	1.0	6.7	-0.3	-0.8	-0.4	0.1	0.3	0.2	0.3	-2.6
Financial difficulties in last 2 years	0.9	1.1	2.4	-0.2	-0.1	1.1	-1.6	-1.0	-0.4	1.4	1.5
Mouth/teeth dental problems	0.4	0.6	1.7	0.6	-0.8	-0.4	0.3	0.9	-0.8	0.4	-1.3
Heart attack	0.4	0.5	1.8	-0.2	-1.3	0.3	-0.4	-0.2	-0.5	0.6	-1.1
Allergy	0.8	1.7	3.7	-0.6	-1.8	-1.4	-0.0	-1.9	0.0	1.0	-1.9
Pain all over the body in last month	0.6	0.7	3.7	0.1	0.3	-0.7	-0.4	1.9	-0.7	0.4	-0.5
Diabetes (self-reported)	1.5	2.4	9.9	1.4	-2.2	-0.0	0.8	-0.2	1.0	-0.7	-3.1
Hayfever/allergic rhinitis (self-reported)	1.5	1.9	3.3	1.6	1.8	1.8	1.7	1.3	0.5	-1.2	0.5
Medication: Ramipril	2.9	3.7	11.3	1.9	1.8	1.5	0.9	2.1	3.4	-2.1	-0.4
Medication: Simvastatin	0.2	0.3	1.0	0.2	-1.0	0.5	-0.5	0.8	-0.4	0.1	-0.7
Fluid intelligence score	1.6	3.3	9.6	0.9	2.3	1.5	1.1	3.1	0.4	-2.1	1.7
Illnesses of siblings	1.3	1.8	5.3	-0.6	-1.2	-1.6	-1.5	-0.8	-0.1	2.3	1.3
Neuroticism score	0.4	0.8	2.3	-0.4	-0.9	0.1	1.2	0.6	-1.0	0.4	-1.5
Weight	0.8	3.8	14.6	1.0	-2.1	-0.9	0.6	3.0	0.3	0.3	-3.8
Impedance of arm (right)	1.1	5.3	17.5	-1.5	4.2	1.3	1.2	-0.1	-1.2	-2.6	3.3
Arm fat percentage (right)	0.4	1.6	6.1	-0.3	-1.1	-1.5	0.5	1.5	-0.8	0.2	-2.5
Trunk fat-free mass	0.8	4.4	14.0	2.1	-2.7	-0.3	0.2	2.6	1.6	0.6	-3.7
Hip circumference	0.8	3.4	14.6	1.8	-1.7	-0.9	0.8	1.9	1.0	0.3	-3.8
Time employed in main current job	0.6	0.7	1.9	-1.2	1.4	-0.1	0.4	0.6	1.2	-0.7	0.5
Alcohol intake versus 10 years previously	0.6	0.8	2.0	0.0	0.4	0.2	-1.3	-1.0	-1.4	0.8	1.0
Father’s age at death	1.1	1.5	5.2	-0.2	-0.3	-0.7	-1.1	-2.3	-0.7	0.9	1.8
Worrier / anxious feelings	0.5	0.9	3.1	-0.7	0.1	0.4	0.7	-1.5	-1.8	-0.2	0.8
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.5	4.1	-1.1	-1.6	-1.2	-0.2	-0.8	-0.9	1.2	-2.0
Falls in the last year	1.5	2.1	8.0	0.8	0.3	-0.1	2.8	-0.5	2.1	-1.2	-1.4
Hair/balding pattern: Pattern 3	1.8	2.7	10.6	3.3	0.7	0.8	1.5	1.4	1.3	-1.7	-0.9
Number of live births	0.8	1.2	3.6	0.4	-1.3	-0.6	0.5	1.1	1.9	0.4	-1.3
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	2.9	-0.7	-1.3	-1.2	-1.2	0.2	-1.0	1.7	1.1
Pulse rate	0.8	1.3	2.6	1.5	-0.8	-0.2	-1.6	-1.2	-0.8	0.7	1.4
Happiness	0.9	1.1	2.2	-0.2	0.6	1.2	1.5	0.9	1.5	-1.2	-0.4
Noisy workplace	1.8	2.2	5.5	-0.8	-2.0	-0.8	-1.3	-1.4	-1.8	2.4	-0.4
Qualifications: A levels/AS levels or equivalent	0.5	1.2	4.0	-0.7	2.0	-0.3	1.2	0.3	-0.4	-1.3	1.2
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	2.0	0.3	1.4	0.9	-0.1	0.3	-0.4	-0.6	0.0
Mouth/teeth dental problems: Dentures	0.2	0.4	1.3	-0.7	1.2	-0.3	-0.2	-0.8	0.4	0.3	0.6
Asthma	0.8	1.5	5.1	-0.4	1.9	0.5	-0.6	2.3	-0.6	-0.3	1.4
Medication: Ibuprofen (e.g. Nurofen)	1.3	1.6	3.4	-1.8	-1.0	-1.7	0.2	-0.2	-1.6	1.7	-0.3
Medication: Cholesterol lowering	2.3	3.6	6.2	1.3	0.0	1.5	2.4	1.7	1.9	-2.4	-2.5
Depression (self-reported)	1.7	2.0	5.1	-0.9	-1.3	-0.9	-1.9	0.5	-1.0	1.8	2.3
Medication: Lansoprazole	1.5	1.7	3.6	-1.5	-1.8	-1.1	-0.8	0.7	-1.9	1.5	-0.2
Prospective memory result	0.8	1.0	2.4	-1.2	1.3	1.0	-0.5	-1.6	0.9	-0.2	0.7
Lung cancer (father)	1.0	1.1	2.8	0.9	0.7	1.7	1.4	-0.5	0.2	-1.3	-1.1
Illnesses of mother	1.4	1.8	5.0	0.4	1.0	-0.1	-1.1	2.2	-1.8	0.5	1.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.5	3.5	-0.5	-1.6	-1.4	-1.6	-0.3	-0.5	1.9	0.9
Pulse wave Arterial Stiffness index	0.8	0.9	3.2	1.8	-0.4	-0.5	0.8	0.9	-0.3	0.3	-1.6
Impedance of arm (left)	1.4	6.5	21.6	-0.9	4.6	2.2	1.8	0.8	-0.6	-3.2	3.2
Arm fat mass (right)	0.6	2.6	9.8	0.2	-2.0	-1.5	0.2	2.0	-0.3	0.7	-3.1
Trunk predicted mass	0.7	4.1	12.7	2.0	-2.6	-0.3	0.1	2.7	1.5	0.6	-3.6
Standing height	0.3	3.3	13.2	1.1	0.2	1.5	1.5	3.6	1.8	-1.8	-1.1
Length of working week for main job	0.9	1.0	2.9	-0.8	-0.1	0.4	-1.3	-0.8	1.3	0.0	1.7
Exposure to tobacco smoke at home	0.4	0.5	2.0	-0.5	-0.7	-0.6	-1.4	0.2	0.5	-0.3	-0.2
Breastfed as a baby	0.3	0.4	0.9	-0.2	0.5	0.7	-0.3	-0.8	0.1	-0.9	0.8
Tense / ‘highly strung’	0.6	1.1	4.5	-0.0	-2.1	-0.3	-0.4	0.2	-0.7	1.0	-1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	6.5	-0.4	0.5	0.4	0.7	2.6	-1.0	-0.3	0.7
Hair/balding pattern: Pattern 4	0.2	0.4	1.6	0.1	0.6	1.3	0.4	-0.5	0.1	-0.4	0.5
Birth weight of first child	4.3	7.8	14.6	2.5	1.3	2.6	3.2	2.4	3.8	-3.8	-1.7
Peak expiratory flow (PEF)	0.0	0.1	0.2	-0.2	-0.2	-0.1	0.2	0.5	-0.2	-0.1	0.5
Pulse wave reflection index	0.9	1.1	4.7	0.4	-1.1	0.0	1.4	0.8	0.3	-0.3	-2.2
Ever highly irritable/argumentative for 2 days	0.3	0.3	0.8	0.1	-0.6	0.4	-0.9	-0.3	-0.2	0.9	0.6
Loud music exposure frequency	2.5	2.7	5.5	-1.5	-1.4	-2.4	-1.9	0.4	-1.5	2.3	-0.5
Qualifications: O levels/GCSEs or equivalent	0.7	1.0	3.3	0.9	0.8	0.4	0.6	1.8	-0.0	-0.9	1.5
Mouth/teeth dental problems: Bleeding gums	0.3	0.3	0.7	-0.5	0.8	0.8	0.0	0.6	0.2	-0.7	0.4
Blood clot in the leg (DVT)	0.2	0.2	1.4	-0.4	-0.2	0.4	0.2	1.2	0.1	-0.2	-0.0
Medication: Paracetamol	2.6	4.3	11.2	-1.6	-2.7	-3.3	-1.6	-0.5	-0.0	3.0	-1.3
Headache pain in last month	1.5	2.5	6.8	-0.4	-2.6	-2.1	-0.5	-0.2	-0.9	2.6	-0.9
Medication for cholesterol, blood pressure or diabetes	0.6	1.1	4.5	-0.3	-0.3	-0.5	-1.0	-0.7	-0.9	1.1	2.1
Glaucoma (self-reported)	0.4	0.5	1.6	-0.5	-0.9	0.4	0.6	-0.1	-1.3	-0.7	-0.7
Gout (self-reported)	0.7	1.0	2.7	-0.7	1.5	1.4	0.6	0.3	0.1	-0.6	1.6
Hypothyroidism/myxoedema (self-reported)	0.9	1.8	3.6	1.0	1.5	1.6	1.3	1.1	-1.3	-1.9	-0.7
Medication: Amlodipine	0.4	0.6	1.6	-1.1	1.3	-0.6	0.4	-0.2	1.0	-0.4	-0.3
Medication: Ventolin 100micrograms inhaler	0.5	0.6	1.9	0.3	1.4	0.9	-0.8	0.2	-0.2	-0.6	1.1
Birth weight	0.9	1.9	4.3	0.7	2.1	1.0	1.0	1.5	1.6	-1.9	0.5
Chronic bronchitis/emphysema (mother)	0.4	0.5	2.0	-1.0	-0.5	-1.4	0.2	0.7	0.4	0.3	-0.6
High blood pressure (siblings)	1.0	1.5	4.8	0.5	0.8	1.2	1.1	1.0	0.6	-1.3	-2.2
Forced vital capacity (FVC), Best measure	0.4	1.5	4.7	-0.6	-1.3	-1.1	-1.6	0.3	-0.4	2.2	1.2
Body fat percentage	0.4	1.6	5.3	-0.4	-1.1	-1.4	0.8	1.6	-0.8	0.0	-2.3
Leg fat percentage (right)	0.9	3.2	6.8	-0.9	-2.6	-2.5	-0.4	0.3	-1.6	1.6	-2.5
Arm fat-free mass (right)	0.9	4.5	12.2	2.0	-3.0	-0.4	-0.1	2.6	1.5	1.1	-3.5
Exposure to tobacco smoke outside home	0.8	1.1	2.4	-0.6	1.5	1.6	0.8	0.6	-0.1	-1.5	0.8
Comparative body size at age 10	1.3	3.5	9.2	-0.8	-1.5	-3.0	-0.8	-1.8	-1.8	1.7	-2.5
Number of full brothers	2.8	3.5	10.4	-0.3	-3.2	-0.6	-2.3	-0.7	-2.4	2.4	-0.0
Worry too long after embarrassment	0.8	1.3	3.1	-0.0	1.4	0.7	1.7	-1.1	1.7	-1.1	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.1	4.3	-0.6	0.8	0.5	0.2	2.1	-1.7	-0.4	0.7
Wheeze or whistling in the chest in last year	0.7	1.2	2.6	-0.8	1.6	1.0	-1.4	0.7	-0.3	-0.3	1.6
Number of children fathered	1.6	1.8	6.2	-0.3	-0.8	-0.7	-2.3	-0.1	-2.5	1.1	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	3.0	-0.7	0.3	-0.2	-1.0	0.1	-0.2	0.3	1.7
Age at first live birth	0.9	1.6	3.3	-0.6	1.7	1.1	1.8	-0.6	1.2	-1.5	0.6
Pulse wave peak to peak time	0.6	0.7	2.6	-1.6	0.1	0.5	-0.7	-0.7	0.4	-0.3	1.3
Health satisfaction	1.4	1.8	7.4	-0.3	-1.0	-0.8	1.6	0.9	2.7	-0.3	-1.5
Shortness of breath walking on level ground	0.3	0.3	1.3	0.8	-1.1	0.3	-0.1	-0.1	-0.2	0.4	-0.7
Qualifications: College or University degree	1.3	4.1	7.8	1.7	2.6	2.8	2.1	0.0	1.5	-2.7	0.9
Eye problems/disorders: None of the above	1.6	1.8	9.3	-0.4	1.3	0.1	-1.5	0.3	-0.8	0.5	3.1
Mouth/teeth dental problems: Loose teeth	0.8	1.0	4.0	0.7	-0.4	0.3	0.8	0.8	2.0	-0.2	-1.4
Emphysema/chronic bronchitis	0.8	0.9	3.1	-0.1	0.9	0.7	1.0	-0.3	1.8	-1.1	-0.3
Medication for pain relief, constipation, heartburn	2.4	4.0	9.4	2.4	2.0	3.1	1.5	0.5	1.0	-2.7	1.5
Neck or shoulder pain in last month	0.6	0.8	2.2	-1.3	-0.3	-0.1	1.5	-0.4	0.3	0.5	-1.5
Medication: Blood pressure	0.4	0.7	4.5	-0.1	-0.0	0.3	0.6	0.7	-0.0	-0.2	-2.1
Angina (self-reported)	0.7	0.9	3.1	0.5	-1.7	0.5	-0.0	0.5	0.8	0.5	-1.7
Migraine (self-reported)	1.0	1.2	3.1	0.1	-1.4	1.8	0.8	-0.6	0.0	0.9	-1.6
Medication: Ibuprofen	1.4	1.7	3.4	-1.6	-1.0	-1.9	0.3	0.2	-1.8	1.7	-0.2
Medication: Allopurinol	0.7	0.9	2.0	0.8	1.4	1.4	0.3	0.8	0.6	-0.4	1.3
Medication: Omeprazole	0.5	0.6	1.7	-0.1	1.3	0.6	1.0	0.1	0.8	-0.9	0.3
Medication: Seretide 50 evohaler	0.2	0.2	1.4	0.0	0.5	0.1	0.3	0.0	1.2	-0.4	0.2
Mean time to correctly identify matches	0.4	0.8	2.0	-0.5	0.2	0.2	-1.2	-1.2	-0.4	1.1	1.4
Heart disease (mother)	1.0	1.2	2.5	1.4	-1.6	0.6	0.9	-0.4	1.3	0.4	-1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	0.8	0.8	0.0	0.7	-0.9	0.2	-0.1	-0.2	0.2
Whole body fat mass	0.6	2.6	9.6	0.1	-2.0	-1.6	0.6	2.1	-0.3	0.5	-3.1
Leg fat mass (right)	1.0	3.8	12.0	0.1	-2.9	-2.2	-0.1	1.6	-0.4	1.5	-3.5
Arm predicted mass (right)	0.9	4.8	12.2	2.2	-3.2	-0.5	-0.0	2.7	1.5	1.1	-3.5
Pulse rate, automated reading	0.7	2.1	8.1	2.8	-2.0	0.2	-1.1	-0.5	0.3	1.4	1.1
Alcohol intake frequency.	0.7	1.7	5.6	-0.6	-2.4	-1.1	-1.4	-1.4	-1.1	1.0	-0.4
Comparative height size at age 10	0.3	1.6	8.1	0.5	-2.8	-0.7	0.5	0.1	0.7	0.9	-1.6
Number of full sisters	1.1	1.3	5.1	-1.0	-2.2	-0.7	-1.1	-1.5	-0.2	0.2	0.6
Suffer from ‘nerves’	0.7	1.1	4.0	-0.9	-1.6	-0.3	0.0	-0.6	-2.0	0.9	-0.2
Overall health rating	0.9	1.9	7.8	-1.1	-0.6	-1.1	1.1	1.0	1.5	0.1	-2.8
Chest pain or discomfort	1.0	1.5	5.8	0.4	-1.5	-0.7	-0.0	0.5	-0.9	1.4	-2.4
Had major operations	0.3	0.3	0.8	0.2	0.3	0.9	0.7	-0.5	-0.5	-0.4	-0.5
Age at last live birth	1.3	1.8	4.8	-0.6	1.4	2.2	1.0	0.8	1.5	-1.5	1.2
Family relationship satisfaction	1.0	1.2	2.2	1.0	-0.2	0.5	1.3	1.5	-0.9	-1.2	-1.5
Leg pain on walking	0.3	0.4	2.3	0.1	-0.4	0.5	0.5	0.2	-0.1	-0.4	-1.5
Qualifications: NVQ or HND or HNC or equivalent	2.2	2.6	5.3	-0.4	-2.3	-1.8	-1.0	-2.0	-1.5	2.2	0.2
Commuting to job workplace: Car/motor vehicle	0.1	0.2	0.5	-0.2	-0.7	0.7	-0.2	-0.1	0.4	-0.3	0.1
Illness, injury, bereavement, stress in last 2 years	0.4	0.4	2.0	0.7	0.0	-0.2	1.4	0.3	0.5	-0.3	-0.7
Medication: Aspirin	0.3	0.4	0.9	-0.8	-0.3	-0.7	-0.5	0.5	0.5	0.1	-0.9
Supplements: Vitamin C	0.4	0.5	0.9	0.8	0.8	0.0	-1.0	0.4	0.6	0.9	0.6
Knee pain experienced in last month	1.4	2.2	4.2	-1.6	-1.8	-2.0	-1.8	-0.6	0.9	1.8	0.6
Hypertension (Self-reported)	0.3	0.9	2.5	-1.3	0.7	0.3	0.3	1.6	0.9	-0.2	-1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.8	2.1	4.5	-2.1	-1.3	-1.4	-1.4	-0.8	-1.6	1.9	0.0
Illnesses of father: Heart disease	0.4	0.6	3.2	0.6	0.5	-0.6	0.1	0.7	1.8	-0.3	0.1
Illnesses of siblings: Diabetes	0.2	0.3	0.9	-0.7	-0.4	-0.2	-0.5	-1.0	0.2	-0.4	0.1
Smoking status: Previous	0.7	1.0	3.9	0.8	0.0	-0.5	1.1	2.0	0.0	0.3	-1.4
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.5	5.1	1.5	0.5	0.5	0.3	2.2	1.9	-0.7	0.1
Whole body fat-free mass	0.8	4.8	14.1	2.4	-2.7	-0.1	0.2	3.1	1.3	0.6	-3.8
Leg fat-free mass (right)	0.8	4.5	12.4	2.7	-2.2	0.1	0.2	3.5	1.0	0.5	-3.2
Arm fat percentage (left)	0.4	1.7	6.6	0.2	-0.9	-1.1	0.8	2.0	-0.4	-0.1	-2.6
Average weekly red wine intake	0.6	0.9	3.2	0.1	-0.2	0.8	0.8	-0.6	0.9	-1.8	-1.1
Handedness (chirality/laterality): Left-handed	0.8	1.0	3.5	-1.0	-0.9	-0.8	-1.0	-1.9	-0.0	0.9	0.5
Mood swings	1.7	3.0	6.2	-2.1	-1.9	-1.5	-1.4	-0.6	-2.5	2.3	-0.4
Loneliness, isolation	0.6	0.9	2.4	-0.3	1.3	0.4	1.5	0.4	0.4	-1.0	-1.2
Long-standing illness, disability or infirmity	0.5	0.7	3.5	-0.1	0.1	0.1	0.8	0.4	0.9	-0.8	-1.9
Ever had bowel cancer screening	0.6	0.7	3.9	0.7	0.4	-0.1	-0.5	0.4	-2.0	0.6	-0.0
Diabetes diagnosed by doctor	1.7	2.9	10.1	1.4	-2.7	-0.3	1.0	-0.6	1.3	-0.5	-3.2
Ever had stillbirth, spontaneous miscarriage or termination	1.3	1.4	5.3	-1.4	-2.3	-0.9	-0.9	0.4	0.2	1.1	-1.0
Friendships satisfaction	0.8	1.0	3.1	-0.5	-0.1	0.8	1.2	1.3	0.1	-1.8	-0.9
Qualifications: nursing, teaching	1.4	2.2	5.3	-0.2	2.3	1.0	1.7	1.0	1.8	-1.5	1.4
Commuting to job workplace: Walk	0.4	0.4	1.2	0.7	0.5	-0.2	0.4	0.3	1.0	-0.4	-1.1
Eye problems/disorders: Cataract	1.6	1.8	5.4	1.1	-0.1	0.9	1.8	-0.5	1.8	-0.6	-2.3
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.4	0.7	-1.2	-0.1	0.5	-0.4	0.2	-0.2	-0.3
Medication for cholesterol	1.7	2.6	5.4	1.6	0.4	2.1	1.8	-0.7	2.1	-2.3	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	1.5	0.7	-1.1	-0.6	0.0	1.2	-0.4	-0.2	-1.0
Back pain experienced in last month	0.7	1.0	3.7	-0.3	0.6	-0.3	-0.7	1.9	1.8	0.1	-0.5
Mineral and other dietary supplements	1.5	2.0	7.0	0.6	-2.5	-0.3	0.8	-1.2	0.5	0.4	-2.6
Breast cancer (self-reported)	0.8	0.9	4.1	1.3	-0.8	0.2	0.6	0.2	2.0	0.6	-0.2
Asthma (self-reported)	0.7	1.5	4.9	-0.4	1.9	0.7	-0.5	2.2	-0.5	-0.5	1.3
Osteoporosis (self-reported)	0.8	1.0	4.8	-1.1	1.1	-0.2	0.2	0.0	0.6	-0.2	2.2
Osteoarthritis (self-reported)	0.3	0.4	2.1	0.4	-0.7	0.4	0.5	-1.5	0.3	0.1	-0.2
Medication: Aspirin	0.4	0.6	1.3	-0.8	-0.2	-1.1	-0.6	0.8	0.2	0.4	-1.1
Medication: Gliclazide	1.0	1.1	4.3	2.1	0.3	0.7	0.5	0.4	0.6	-0.5	-1.7
Illnesses of father: None of the above (group 1)	0.5	0.6	1.6	-0.2	0.6	1.2	0.8	-0.1	-1.3	-0.7	-0.5
Smoking status: Current	0.6	1.0	3.9	-0.7	0.1	1.6	-0.3	2.0	-0.8	-0.0	-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.1	0.4	0.1	-0.2	-0.6	0.3	-0.6	0.2	0.2	0.3
Whole body water mass	0.8	4.8	14.1	2.4	-2.7	-0.1	0.2	3.1	1.2	0.5	-3.8
Leg predicted mass (right)	0.8	4.4	12.1	2.7	-2.1	0.2	0.1	3.5	1.0	0.5	-3.1
Arm fat mass (left)	0.6	2.4	8.9	0.6	-1.8	-1.2	0.5	2.3	-0.2	0.3	-3.0
Number of self-reported non-cancer illnesses	0.5	1.0	3.5	-0.7	1.9	0.6	0.3	1.5	0.3	-0.7	-0.6
Average weekly champagne plus white wine intake	0.6	0.8	3.3	-1.4	-0.2	-0.2	-0.8	-0.5	0.2	0.4	1.8
Miserableness	0.9	1.5	4.3	-1.3	-0.5	-0.9	-0.9	1.2	-2.1	1.6	0.1
Guilty feelings	0.3	0.5	1.4	0.7	0.0	0.5	1.2	0.1	0.1	-0.7	-1.1
Wears glasses or contact lenses	0.6	0.7	2.8	-0.2	0.5	0.4	1.7	-0.6	0.3	-1.1	-0.9
Ever taken oral contraceptive pill	0.8	0.9	3.6	0.3	1.2	0.8	0.6	1.9	-0.9	-0.3	-0.2
Hearing aid user	1.7	1.9	6.1	0.3	0.3	1.5	2.5	0.7	1.2	-1.9	-1.3
Mother’s age at death	0.2	0.2	0.4	-0.3	0.7	0.2	0.5	0.5	0.3	-0.7	0.0
Financial situation satisfaction	0.7	0.8	1.7	1.0	-1.3	0.4	0.1	-1.1	1.1	0.4	-1.0
Tinnitus: Yes, now most or all of the time	0.7	0.8	3.0	0.9	1.7	-1.1	-0.2	1.1	-0.3	0.0	0.4
Commuting to job workplace: Public transport	0.3	0.3	1.5	0.0	0.8	1.2	0.7	0.1	-0.3	0.0	0.0
Eye problems/disorders: Glaucoma	0.3	0.4	1.7	-1.3	-0.1	0.1	0.0	-0.5	-0.9	-0.2	0.6
Medication: Blood pressure	1.2	2.3	8.4	-2.9	0.3	-1.8	-1.5	0.9	-1.1	1.4	0.3
Pain type(s) experienced in last month: Hip pain	1.4	1.7	5.5	1.0	-2.4	0.6	1.1	1.9	0.0	-0.8	-1.3
Supplements: Fish oil (including cod liver oil)	1.1	1.5	5.1	-0.2	2.3	0.4	-0.6	1.5	0.3	-0.4	1.9
High cholesterol (Self-reported)	0.4	0.6	2.4	0.5	-1.0	-0.1	0.6	1.0	0.2	-0.4	-1.6
Medication: Bendroflumethiazide	0.9	1.3	3.2	-1.7	0.8	-0.9	-1.8	0.9	0.2	1.2	0.7
Medication: Paracetamol	2.3	3.5	9.1	-1.5	-2.4	-3.0	-1.1	-0.4	-0.0	2.7	-1.6
Medication: Lisinopril	0.5	0.7	1.8	0.4	0.6	1.0	1.3	0.9	-0.1	-0.5	-1.2
Medication: Atorvastatin	0.7	0.9	1.8	0.7	-0.2	0.0	1.2	1.3	1.2	-1.0	-0.9
Illnesses of father: High blood pressure	1.1	1.4	4.2	0.1	-1.0	-2.0	-1.5	-0.2	-0.3	1.9	-0.4
Alcohol drinker status: Never	0.6	0.7	3.2	-0.7	-0.8	-0.7	0.0	-1.8	0.3	-0.7	-0.6
Ever smoked	0.8	1.4	6.7	-0.1	1.2	1.2	0.6	2.6	-0.9	-0.5	-0.6
Basal metabolic rate	0.9	4.7	14.7	2.1	-2.8	-0.4	0.1	3.1	0.9	0.7	-3.8
Leg fat percentage (left)	0.9	3.2	7.3	-0.8	-2.7	-2.5	-0.7	-0.4	-1.8	1.7	-2.1
Arm fat-free mass (left)	0.7	3.8	9.9	1.4	-3.0	-1.0	-0.5	2.4	0.6	1.4	-3.1
Number of operations (self-reported)	0.9	1.3	4.0	1.8	-0.9	-0.1	0.7	1.2	-0.3	0.2	-2.0
Average weekly beer plus cider intake	0.5	0.8	2.7	-0.6	-0.6	-0.7	-0.6	-0.4	1.6	1.2	-0.6
Irritability	0.5	0.9	3.3	-0.2	-0.9	0.0	-0.1	1.8	-1.5	0.8	-0.2
Risk taking	0.7	1.0	2.6	0.3	1.4	1.0	-0.4	0.0	1.6	-1.1	0.9
Ever had prostate specific antigen (PSA) test	0.8	0.9	2.5	0.2	-0.2	0.5	-1.6	-0.4	0.6	1.4	1.4
Fractured/broken bones in last 5 years	2.3	2.9	5.9	1.2	1.6	1.4	2.4	0.7	1.8	-2.3	-1.7
Age started oral contraceptive pill	0.3	0.4	1.9	-0.7	0.5	-0.4	0.6	-1.4	-0.1	0.1	0.6
Diastolic blood pressure, automated reading	0.4	1.3	5.3	0.3	1.6	0.7	0.8	0.8	2.3	-0.6	0.6
Ever depressed for a whole week	0.8	1.0	2.6	0.3	0.9	1.6	1.0	1.6	0.2	-0.6	0.9
Unable to work because of sickness or disability	0.5	0.7	1.3	0.7	0.9	-0.0	0.9	0.9	1.0	-0.6	-1.1
Commuting to job workplace: Cycle	0.4	0.4	1.8	1.4	-0.9	0.2	-0.0	0.3	0.1	0.8	0.4
Myopia	0.2	0.2	0.6	0.3	-0.3	0.4	-0.2	0.8	0.6	-0.2	-0.6
Vascular/heart problems diagnosed by doctor	0.4	1.2	4.1	1.1	-0.0	-0.2	-0.4	-1.6	-1.2	-0.0	2.0
Cholesterol lowering medication	1.6	2.4	4.2	-1.6	-1.4	-2.1	-1.6	-0.6	-1.8	2.0	-0.2
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	1.5	-1.2	0.1	-0.3	-0.2	0.3	-0.0	0.3	0.1
Pain experienced in last month	1.2	2.0	7.2	0.1	2.7	1.6	0.5	-0.7	-0.3	-1.8	1.5
Supplements: Calcium	1.4	1.6	5.2	-0.3	2.0	0.3	-0.5	1.6	-0.3	-0.6	2.3
Basal cell carcinoma (self-reported)	0.6	0.7	1.8	-0.1	-0.5	-1.0	-0.6	0.9	-1.3	0.9	-0.8
Heart attack/myocardial infarction (self-reported)	0.6	0.7	3.1	-0.1	-1.8	0.2	-0.4	-0.3	-0.4	0.8	-1.4
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.1	-0.0	0.3	0.8	0.7	1.1	0.8	-0.6	-0.0
Heart disease (siblings)	1.2	1.5	6.3	0.4	-0.6	1.6	0.9	2.5	0.3	-0.7	-1.0
Alcohol drinker status: Previous	0.4	0.5	2.0	-0.2	-0.4	0.6	0.7	1.4	0.0	-0.9	-0.0
Pack years of smoking	0.5	0.7	2.5	0.2	-0.2	1.5	0.6	0.2	0.6	-1.6	-0.2
Impedance of whole body	1.0	5.2	18.5	-2.2	3.5	0.9	0.5	-0.8	-0.8	-1.9	4.3
Leg fat mass (left)	0.9	3.7	10.9	0.1	-3.0	-2.2	-0.2	1.3	-0.6	1.5	-3.3
Arm predicted mass (left)	0.8	4.1	11.2	1.5	-3.3	-0.9	-0.6	2.2	0.5	1.4	-3.3