[Hub]/) : Traits : Blood Platelet Count :

chr16:74,578,110-76,197,034

Best TWAS P=9.68e-20 · Best GWAS P=4.13e-20 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CFDP1 0.08 0.04 lasso 4 0.04 1.6e-05 -8.6 -8.0 1.8e-15 0.93 0.03 0.97 FALSE
2 GTEx Adipose Subcutaneous CFDP1 0.11 0.09 lasso 2 0.09 1.1e-07 -5.5 -5.5 4.2e-08 0.65 0.78 0.21 FALSE
3 GTEx Adipose Subcutaneous TMEM170A 0.11 0.00 lasso 5 0.01 6.7e-02 -6.1 -6.0 1.4e-09 0.79 0.03 0.87 FALSE
4 GTEx Adrenal Gland TMEM170A 0.11 0.06 enet 4 0.04 1.7e-02 -9.1 9.1 9.7e-20 -0.98 0.02 0.92 TRUE
5 GTEx Artery Aorta BCAR1 0.18 0.13 lasso 3 0.11 9.8e-07 -9.1 8.9 6.4e-19 -0.98 0.02 0.98 FALSE
6 GTEx Artery Tibial BCAR1 0.07 0.06 lasso 1 0.04 2.4e-04 -8.8 8.8 1.0e-18 -0.99 0.03 0.96 FALSE
7 GTEx Brain Cerebellum BCAR1 0.18 0.08 enet 12 0.09 1.1e-03 -8.6 -7.6 2.6e-14 0.77 0.05 0.79 FALSE
8 GTEx Brain Cerebellum CFDP1 0.25 -0.01 lasso 2 0.05 1.7e-02 -9.1 -8.5 1.4e-17 0.81 0.02 0.88 FALSE
9 GTEx Brain Cortex CFDP1 0.18 0.07 lasso 3 0.08 3.4e-03 -4.9 -6.1 8.4e-10 0.77 0.04 0.76 FALSE
10 GTEx Cells EBV-transformed lymphocytes TMEM170A 0.13 0.07 lasso 3 0.02 6.2e-02 -8.6 -8.1 7.9e-16 0.78 0.04 0.76 FALSE
11 GTEx Cells Transformed fibroblasts CFDP1 0.17 0.20 enet 10 0.24 9.9e-18 -8.6 -8.3 1.1e-16 0.96 0.11 0.89 FALSE
12 GTEx Esophagus Gastroesophageal Junction CFDP1 0.31 0.17 lasso 4 0.16 3.0e-06 -4.9 -5.2 1.9e-07 0.61 0.56 0.38 FALSE
13 GTEx Esophagus Mucosa BCAR1 0.16 0.13 lasso 8 0.14 1.8e-09 -9.1 -8.9 7.1e-19 0.96 0.02 0.98 FALSE
14 GTEx Nerve Tibial CFDP1 0.16 0.14 lasso 3 0.12 1.6e-08 -5.5 -6.9 7.1e-12 0.79 0.16 0.84 FALSE
15 GTEx Nerve Tibial TMEM170A 0.12 0.09 enet 7 0.11 4.1e-08 -6.4 -8.7 4.6e-18 0.87 0.12 0.88 FALSE
16 GTEx Skin Not Sun Exposed Suprapubic TMEM170A 0.09 0.02 lasso 3 0.05 1.1e-03 -4.7 5.8 6.2e-09 -0.63 0.06 0.86 FALSE
17 GTEx Skin Sun Exposed Lower leg TMEM170A 0.13 0.08 lasso 5 0.06 1.2e-05 -8.6 7.9 3.2e-15 -0.76 0.04 0.96 FALSE
18 GTEx Thyroid TMEM170A 0.09 0.02 lasso 4 0.00 4.0e-01 -6.1 -6.4 2.0e-10 0.60 0.08 0.69 FALSE
19 METSIM Adipose TMEM170A 0.03 0.01 lasso 3 0.02 1.5e-03 -8.6 -6.9 7.1e-12 0.87 0.06 0.93 FALSE
20 The Cancer Genome Atlas Breast Invasive Carcinoma CFDP1 0.04 0.03 enet 10 0.03 5.2e-07 -5.5 -5.9 3.5e-09 0.67 0.94 0.06 FALSE
21 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CFDP1 0.02 0.02 lasso 4 0.02 1.9e-03 -8.4 -8.3 1.4e-16 0.93 0.03 0.85 FALSE
22 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma CFDP1 0.13 0.07 enet 10 0.10 2.1e-06 -4.9 -5.4 7.7e-08 0.56 0.38 0.34 FALSE
23 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma TMEM170A 0.08 0.10 blup 36 0.13 9.1e-08 -5.7 -8.4 2.8e-17 0.90 0.02 0.98 FALSE
24 The Cancer Genome Atlas Brain Lower Grade Glioma CFDP1 0.04 0.02 lasso 6 0.03 4.0e-04 -5.0 -7.3 2.6e-13 0.87 0.04 0.95 FALSE
25 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CFDP1 0.23 0.00 blup 70 0.02 4.2e-02 -4.9 -6.3 2.6e-10 0.65 0.03 0.20 FALSE
26 The Cancer Genome Atlas Testicular Germ Cell Tumors CFDP1 0.10 0.00 blup 70 0.04 1.4e-02 -8.4 -8.1 4.8e-16 0.89 0.02 0.46 FALSE
27 The Cancer Genome Atlas Testicular Germ Cell Tumors CHST6 0.20 0.08 enet 10 0.10 2.2e-04 -9.1 6.9 5.4e-12 -0.86 0.01 0.92 FALSE