[Hub]/) : Traits : Blood Platelet Count :

chr16:85,011,622-86,515,110

Best TWAS P=4.74e-28 · Best GWAS P=7.21e-52 conditioned to 5.04e-52

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Testis GINS2 0.21 0.01 enet 12 0.00 2.5e-01 7.4 6.6 3.8e-11 -0.07 0.16 0.05 FALSE
2 GTEx Thyroid GINS2 0.28 0.12 lasso 7 0.12 8.9e-10 10.0 10.0 1.9e-23 -0.07 0.04 0.96 FALSE
3 GTEx Vagina RNU1-103P 0.44 0.07 lasso 6 0.09 4.6e-03 9.3 11.0 4.7e-28 0.00 0.08 0.15 TRUE
4 YFS Blood GINS2 0.07 0.06 enet 18 0.07 1.3e-22 8.5 9.3 1.5e-20 -0.03 1.00 0.00 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma GINS2 0.02 0.03 lasso 3 0.02 4.7e-05 9.0 9.3 1.3e-20 -0.05 0.15 0.80 FALSE
6 The Cancer Genome Atlas Lung Squamous Cell Carcinoma GINS2 0.08 0.01 lasso 5 0.02 2.1e-03 8.5 -9.0 2.6e-19 0.08 0.14 0.29 FALSE
7 The Cancer Genome Atlas Prostate Adenocarcinoma GINS2 0.05 0.06 lasso 2 0.05 1.4e-05 9.2 9.9 2.8e-23 -0.02 0.12 0.87 FALSE
8 The Cancer Genome Atlas Thyroid Carcinoma GINS2 0.14 0.10 enet 8 0.13 7.7e-13 9.3 10.0 2.1e-23 -0.03 0.62 0.38 FALSE
9 The Cancer Genome Atlas Thyroid Carcinoma KIAA0182 0.03 0.00 blup 45 0.02 3.5e-03 9.0 -10.2 1.9e-24 0.06 0.01 0.68 FALSE