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Traits
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Blood Platelet Count
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chr2:60,598,672-62,123,953
Best TWAS P=3.79e-10 · Best GWAS P=2.45e-10 conditioned to 1
60.6M
60.8M
61M
61.2M
61.4M
61.6M
61.8M
62M
62.2M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
GTEx
Esophagus Muscularis
RP11-493E12.2
0.05
0.09
lasso
3
0.06
2.0e-04
6.3
-6.3
3.8e-10
-0.99
0.02
0.98
TRUE
2
GTEx
Adipose Subcutaneous
RP11-493E12.2
0.05
0.02
lasso
4
0.03
1.3e-03
6.3
-5.5
3.0e-08
-0.98
0.02
0.97
FALSE
5
GTEx
Ovary
RP11-493E12.2
0.14
0.12
lasso
7
0.13
5.0e-04
5.7
-5.4
5.6e-08
-0.94
0.08
0.80
FALSE
1
CommonMind
Brain Pre-frontal Cortex
LOC339803
0.06
0.05
enet
15
0.05
1.8e-06
-3.3
-5.3
1.1e-07
-0.67
0.19
0.80
FALSE
3
GTEx
Esophagus Muscularis
KIAA1841
0.06
0.10
enet
10
0.10
9.0e-07
5.6
5.3
1.1e-07
0.92
0.04
0.96
FALSE