Best TWAS P=3.79e-10 · Best GWAS P=2.45e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | LOC339803 | 0.06 | 0.05 | enet | 15 | 0.05 | 1.8e-06 | -3.3 | -5.3 | 1.1e-07 | -0.67 | 0.19 | 0.80 | FALSE |
| 2 | GTEx | Adipose Subcutaneous | RP11-493E12.2 | 0.05 | 0.02 | lasso | 4 | 0.03 | 1.3e-03 | 6.3 | -5.5 | 3.0e-08 | -0.98 | 0.02 | 0.97 | FALSE |
| 3 | GTEx | Esophagus Muscularis | KIAA1841 | 0.06 | 0.10 | enet | 10 | 0.10 | 9.0e-07 | 5.6 | 5.3 | 1.1e-07 | 0.92 | 0.04 | 0.96 | FALSE |
| 4 | GTEx | Esophagus Muscularis | RP11-493E12.2 | 0.05 | 0.09 | lasso | 3 | 0.06 | 2.0e-04 | 6.3 | -6.3 | 3.8e-10 | -0.99 | 0.02 | 0.98 | TRUE |
| 5 | GTEx | Ovary | RP11-493E12.2 | 0.14 | 0.12 | lasso | 7 | 0.13 | 5.0e-04 | 5.7 | -5.4 | 5.6e-08 | -0.94 | 0.08 | 0.80 | FALSE |