Hub : Genes

KIAA1841

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0460 0.0160 3.0e-07 0.055 0.053 0.058 0.051 0.056 2.9e-07 4.2e-07 1.2e-07 6.6e-07 2.3e-07
2 GTEx Adrenal Gland 0.1280 0.0570 4.7e-03 0.008 NA 0.024 NA 0.004 1.6e-01 NA 4.6e-02 NA 2.3e-01
3 GTEx Brain Cerebellar Hemisphere 0.1610 0.0710 6.6e-04 0.076 NA 0.089 NA -0.009 5.4e-03 NA 2.7e-03 NA 6.2e-01
4 GTEx Brain Cerebellum 0.0990 0.0480 2.6e-03 0.048 NA 0.036 NA 0.053 1.6e-02 NA 3.2e-02 NA 1.2e-02
5 GTEx Brain Cortex 0.1080 0.0560 4.6e-03 0.055 NA 0.054 NA 0.057 1.3e-02 NA 1.3e-02 NA 1.1e-02
6 GTEx Brain Nucleus accumbens basal ganglia 0.1710 0.0730 6.1e-04 0.165 NA 0.141 NA 0.177 3.5e-05 NA 1.3e-04 NA 1.7e-05
7 GTEx Brain Putamen basal ganglia 0.1620 0.0850 5.6e-03 0.162 NA 0.107 NA 0.127 1.2e-04 NA 1.7e-03 NA 6.3e-04
8 GTEx Esophagus Muscularis 0.0650 0.0270 1.2e-04 0.104 NA 0.102 NA 0.102 7.2e-07 NA 9.0e-07 NA 9.7e-07
9 GTEx Nerve Tibial 0.0615 0.0272 2.8e-04 0.010 NA 0.017 NA 0.019 6.1e-02 NA 2.2e-02 NA 1.5e-02
10 GTEx Thyroid 0.0630 0.0290 1.4e-03 0.006 NA 0.020 NA 0.010 1.0e-01 NA 1.0e-02 NA 5.6e-02
11 ROSMAP Brain Pre-frontal Cortex 0.1428 0.0397 1.0e-12 0.127 0.114 0.093 0.125 0.126 4.8e-16 1.7e-14 4.8e-12 8.2e-16 6.2e-16
12 TCGA Breast Invasive Carcinoma 0.0597 0.0344 4.3e-03 0.001 0.012 0.025 NA 0.001 2.0e-01 1.1e-03 5.4e-06 NA 1.8e-01
13 TCGA Lung Squamous Cell Carcinoma 0.0471 0.0257 4.2e-03 0.016 0.017 0.012 NA 0.013 5.2e-03 4.5e-03 1.4e-02 NA 1.0e-02
14 TCGA Pheochromocytoma and Paraganglioma 0.1620 0.0780 3.1e-03 0.021 0.031 0.029 NA 0.007 4.8e-02 2.1e-02 2.4e-02 NA 1.6e-01

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 0.7 1.1 4.4 -1.6 1.6 -0.1 -1.6 -1.3 0.2 0.1 -1.3 -0.3 0.6 0.1 2.1 -0.7 -0.1
Bipolar Disorder or Schizophrenia 0.5 1.2 6.4 -1.6 0.7 0.0 -1.5 -1.3 0.0 0.3 -1.5 -0.3 0.5 0.1 2.5 -0.8 0.4
Depressed Affect (Nagel 2018) 3.8 8.0 12.8 -2.7 -2.2 -3.6 -2.5 -2.1 -1.8 -3.3 -3.1 -3.1 -3.2 3.3 1.2 -3.5 -3.0
Depression (Nagel 2018) 2.5 3.7 8.4 -1.5 -1.7 -2.6 -1.0 -0.7 -0.5 -2.6 -2.2 -1.7 -1.8 2.9 0.4 -2.0 -2.8
Intelligence (Savage-Jansen 2018) 0.8 2.5 6.4 -2.4 -0.1 -1.2 -2.1 -2.5 -2.1 -0.8 -2.3 -1.5 -0.8 0.9 1.6 -0.1 0.2
Neuroticism (Nagel 2018) 6.0 14.2 21.8 -3.9 -3.0 -4.7 -3.6 -3.5 -3.0 -4.5 -4.3 -4.5 -4.2 4.0 1.2 -3.8 -2.9
Schizophrenia (2018) 0.2 0.4 2.3 -0.7 -0.4 0.1 -0.6 -0.6 -0.1 0.3 -0.9 -0.2 0.2 0.0 1.5 -0.4 0.5
Schizophrenia vs Biploar Disorder 0.1 0.2 1.9 -0.3 -1.4 0.1 -0.2 -0.2 0.1 -0.0 0.2 0.3 0.1 0.3 0.3 0.2 0.1
Worry (Nagel 2018) 5.9 12.4 19.5 -4.0 -2.4 -4.3 -3.7 -3.6 -3.4 -3.8 -4.4 -4.1 -3.4 3.7 1.0 -3.4 -2.7
Alzheimer’s Disease (in mother) 0.6 0.7 3.3 0.5 -0.8 0.5 0.9 0.4 -0.7 1.0 0.6 -0.2 -0.2 -1.0 -1.8 -1.2 0.2
Alzheimer’s Disease (in father) 3.0 3.3 10.4 -2.4 -1.3 -1.8 -2.1 -3.2 -2.1 -0.4 -1.4 -2.1 -1.6 1.1 -1.1 -2.1 -0.2
Alzheimer’s Disease (including proxy) 0.4 0.6 1.9 -0.6 -0.6 -0.0 -0.3 -1.2 -1.4 0.3 0.0 -0.6 -0.1 -0.3 -1.3 -1.4 -0.3
Crohns Disease (2017) 6.4 14.1 26.9 -4.2 -1.4 -4.1 -4.1 -3.9 -5.2 -4.0 -4.0 -4.5 -3.0 3.9 0.6 -3.8 -3.6
Irritable Bowel Disease (IBD) 14.2 33.8 61.3 -5.9 -4.1 -6.6 -6.1 -5.7 -7.6 -5.3 -5.8 -7.8 -6.4 5.3 -0.1 -6.4 -4.3
Ulcerative Colitis (UC) 14.5 27.2 57.2 -5.2 -5.1 -6.2 -5.0 -4.8 -6.4 -3.9 -5.0 -7.6 -6.8 4.1 -1.0 -5.8 -2.6
Major Depression (MDD) 0.2 0.3 1.6 0.3 -0.0 0.4 -0.2 -0.2 0.8 -0.2 -0.3 -0.4 -0.4 0.6 1.2 0.4 -0.0
Reaction Time 1.1 2.1 4.4 2.1 0.9 2.0 1.9 1.5 0.9 0.8 1.8 1.7 1.0 -1.2 -0.5 1.2 1.3
Verbal and Numeric Reasoning (VNR) 1.3 3.2 8.9 -3.0 0.2 -1.1 -2.2 -2.4 -1.9 -1.1 -2.8 -1.6 -1.0 1.6 1.9 0.2 -0.9
Breast Cancer 0.5 1.3 3.5 1.6 0.9 1.1 1.5 1.3 1.9 -0.1 1.2 0.9 0.9 -0.5 0.2 1.5 -0.3
Ovarian Cancer 0.4 0.5 1.8 0.2 0.1 1.1 0.5 0.4 0.3 1.2 0.5 0.5 0.8 -0.2 0.3 1.4 0.8
Prostate Cancer 0.3 0.5 1.4 -0.0 0.6 0.5 0.6 0.6 1.1 1.0 0.2 0.6 0.8 -1.2 -0.2 0.2 0.9
Age at First Birth 7.0 10.2 17.5 -3.9 -2.5 -3.2 -3.3 -4.2 -4.0 -2.5 -3.7 -3.8 -3.6 3.1 0.4 -2.3 -2.0
Bipolar Disorder (2011) 0.5 0.5 2.2 -0.2 1.5 -0.2 -0.4 -0.6 0.0 -1.0 -0.6 0.1 0.2 0.7 -0.7 -0.9 -1.1
Body Mass Index (BMI) (2010) 1.0 1.4 3.8 1.9 0.9 0.9 1.5 1.8 1.9 0.3 1.0 1.1 0.8 -0.7 -0.1 1.2 0.6
Coronary Artery Disease (CAD) 0.3 0.3 1.5 -0.5 0.1 -0.3 -0.3 0.4 0.2 -1.1 -0.9 -0.2 -0.3 1.2 -0.3 0.1 -0.2
Crohns Disease (2012) 2.7 4.3 10.8 -2.1 -0.5 -1.9 -1.9 -1.9 -3.3 -2.0 -1.5 -2.6 -1.6 2.1 -0.4 -2.5 -2.8
Mean Putamen Volume 1.3 1.5 7.3 0.6 -0.3 1.0 -0.8 -0.8 -0.2 1.1 -0.5 -0.1 0.7 -0.9 1.7 2.2 2.7
Fasting Glucose 0.7 0.9 3.7 0.4 -0.6 -0.6 -0.9 -0.6 -1.8 -0.7 0.1 -1.1 -1.9 0.6 0.9 -0.3 -0.3
HbA1C 0.5 0.6 3.5 -0.0 -0.6 0.8 -1.2 -1.0 -0.4 0.1 0.3 -0.2 -0.3 0.5 1.9 0.5 0.7
HDL Cholesterol 0.8 1.3 9.2 -0.4 -0.8 -1.3 -1.0 -0.7 -0.9 -0.7 -0.5 -1.3 -1.1 -0.3 -0.3 -3.0 0.4
LDL Cholesterol 0.2 0.3 0.8 0.9 -0.0 0.1 0.6 0.3 0.4 -0.7 0.8 0.1 0.4 0.7 -0.5 0.7 -0.5
Lupus 2.0 3.0 10.4 -1.1 -1.8 -1.7 -0.8 -1.3 -0.4 -2.0 -0.7 -1.9 -2.4 1.7 -0.8 -2.1 -3.2
Neuroticism (2016) 6.0 8.7 15.8 -3.6 -2.0 -3.2 -3.1 -3.3 -2.5 -2.8 -3.4 -3.2 -2.7 4.0 1.0 -2.7 -2.6
Primary Biliary Cirrhosis 0.5 0.7 2.3 -0.6 0.6 -0.8 -0.7 -0.6 1.1 -1.4 -1.0 0.2 -0.5 1.5 0.4 0.6 -1.2
Rheumatoid Arthritis 1.0 1.4 5.3 1.8 -1.5 0.2 1.2 1.6 0.7 0.2 1.5 0.0 -2.3 -0.2 -1.3 -0.0 -0.2
Schizophrenia (2014) 0.5 1.0 6.2 -1.4 0.3 0.2 -1.1 -1.5 0.0 0.1 -1.4 -0.4 0.2 0.0 2.5 -0.6 0.7
Triglycerides 1.1 1.8 5.2 2.0 0.8 1.1 2.3 2.2 1.4 -0.3 1.4 1.0 0.3 -0.3 -1.2 1.5 -0.6
Type 2 Diabetes (T2D) (2012) 0.5 0.6 1.7 -1.3 -0.1 -0.4 -0.6 -0.7 -1.2 0.8 -0.6 -0.6 -0.7 0.7 0.4 -1.0 -0.4
Ulcerative Colitis 8.7 12.6 28.4 -3.5 -2.9 -4.2 -3.2 -3.1 -4.3 -1.9 -3.0 -5.3 -4.5 2.6 -1.2 -4.9 -2.6
Blood Eosinophil Count 4.0 30.6 62.3 5.3 5.6 7.7 4.3 5.1 3.7 4.2 7.3 7.8 7.9 -4.6 0.3 5.5 2.0
Blood Platelet Count 0.8 9.3 28.3 3.9 2.2 3.0 3.0 3.3 2.9 2.4 5.3 3.8 2.6 -3.0 -2.6 1.2 0.5
Blood Red Count 0.5 4.7 20.1 -4.0 1.3 -1.3 -0.2 -0.5 1.0 -1.6 -2.5 0.2 0.6 3.1 -0.5 -2.5 -4.5
Blood White Count 11.1 82.3 123.2 9.9 5.5 11.1 8.9 9.2 8.6 9.0 10.7 10.9 10.7 -9.4 -1.8 9.0 7.7
Heel T-Score 0.1 0.9 3.5 0.8 -1.1 -0.6 -0.1 0.4 0.6 -1.2 1.2 0.0 -0.8 1.9 -0.8 -0.7 -1.6
BMI 0.5 2.7 11.0 0.8 1.3 1.1 1.6 1.6 3.3 0.3 -1.1 1.2 1.9 -0.9 1.5 1.9 2.3
Height 0.4 7.4 35.8 -0.6 6.0 2.8 0.5 1.1 2.5 2.2 1.4 3.5 3.1 -1.8 3.4 2.5 -1.3
Waist Hip Ratio (WHR) 0.8 3.7 8.7 2.2 1.2 1.8 1.8 1.2 1.0 2.2 2.7 1.4 2.1 -3.0 -2.8 -0.8 0.7
Systolic Blood Pressure 0.6 2.9 14.1 3.8 0.4 1.7 1.7 2.1 1.1 -0.3 2.0 1.2 0.8 -1.4 0.9 2.2 1.1
Smoking Status 1.8 4.3 10.8 3.3 0.6 2.0 3.1 3.0 2.7 1.2 2.1 2.1 1.3 -2.1 -0.4 1.2 1.1
Allergy or Eczema 6.2 16.5 27.8 -5.1 -0.2 -4.3 -5.2 -4.3 -5.3 -3.7 -4.3 -4.0 -2.7 4.4 2.0 -3.7 -4.4
Cardiovascular Disease 2.9 9.5 17.0 4.1 2.8 4.0 2.5 2.2 2.7 2.5 3.4 3.8 3.8 -3.1 0.5 3.1 2.7
Hypothyroidism (self reported) 2.5 5.6 11.7 -2.4 -1.0 -2.7 -2.8 -2.4 -2.3 -3.1 -2.5 -2.3 -2.0 3.4 1.5 -0.9 -2.4
Respiratory disease 1.0 2.3 10.8 -1.0 -2.4 -0.9 -2.2 -1.6 -3.3 -0.3 -0.6 -2.1 -0.4 0.3 0.6 -0.8 0.8
Type 2 Diabetes (T2D) (2018) 0.2 0.3 1.2 0.9 -0.6 0.4 0.5 0.4 0.2 -1.1 0.3 0.4 0.2 0.0 -0.4 0.5 -0.9
Lung FEV1/FVC ratio 5.1 25.7 47.9 -6.9 -3.6 -6.9 -4.7 -4.3 -3.6 -5.2 -6.6 -5.7 -4.6 5.3 -0.5 -5.4 -3.9
Lung FVC 2.3 11.9 22.5 3.6 1.6 3.8 4.2 3.0 3.6 4.5 4.7 3.4 4.1 -2.7 -4.2 1.5 0.6
Neuroticism 5.5 13.2 20.7 -3.5 -3.1 -4.2 -3.3 -3.2 -3.5 -4.5 -4.1 -4.1 -4.1 4.3 0.9 -3.4 -3.2
Chronotype (morning person) 4.1 9.6 21.2 -4.6 -1.6 -3.7 -3.0 -3.1 -2.7 -3.4 -3.4 -2.5 -2.1 4.1 0.2 -2.0 -4.0
Hair Pigment 0.1 1.8 9.4 -0.4 3.1 0.8 -0.1 -0.5 0.8 0.4 -0.8 0.5 1.4 0.1 2.6 2.1 0.8
Tanning 0.2 2.1 5.9 -1.8 -0.9 -1.8 -1.5 -2.0 -1.1 0.5 -1.4 -1.9 -1.4 0.4 -0.7 -2.4 -0.2
Hand grip strength (left) 0.4 1.1 3.2 0.7 0.5 1.5 0.1 -0.0 -0.7 1.0 0.1 -0.0 0.7 -1.5 1.6 1.8 1.6
Number of treatments/medications taken 0.3 0.5 2.5 1.6 0.6 0.9 0.3 0.7 0.1 -0.5 0.9 0.8 0.8 -0.1 0.5 0.5 -0.7
Average weekly spirits intake 0.5 0.7 2.2 -0.1 -0.6 -1.1 -0.0 0.1 -0.5 -1.5 -0.9 -0.7 -1.1 1.0 0.1 -0.6 -1.0
Sensitivity / hurt feelings 0.4 0.7 2.0 -0.1 -0.9 -0.3 -0.7 -0.6 -1.1 -0.2 -0.7 -1.2 -0.9 -0.5 1.0 -0.3 1.4
Frequency of depressed mood in last 2 weeks 3.7 5.1 9.3 -2.1 -2.0 -3.0 -1.9 -1.6 -1.3 -2.5 -2.7 -2.7 -2.7 2.7 1.0 -2.2 -2.2
Hearing difficulty/problems: Yes 0.6 0.9 2.0 -1.1 -1.4 -0.6 -1.1 -1.2 -1.2 -0.5 -1.2 -1.1 -1.0 1.1 0.5 0.1 -0.2
Relative age of first facial hair 4.1 8.5 19.3 -3.6 0.1 -3.4 -2.5 -3.0 -2.2 -2.9 -3.1 -2.6 -2.4 4.1 0.6 -2.8 -4.4
Other serious medical condition/disability diagnosed by doctor 4.0 5.2 10.6 -2.2 -1.1 -2.6 -2.4 -1.6 -3.0 -3.2 -2.6 -2.2 -1.9 2.5 1.3 -1.9 -2.2
Ever used hormone-replacement therapy (HRT) 0.6 0.8 1.9 0.1 -0.5 -0.8 -1.0 -0.6 -0.4 -1.4 -0.8 -0.2 -0.8 1.0 1.4 0.9 1.1
Ever had hysterectomy (womb removed) 1.7 1.9 4.1 -1.1 -1.6 -1.8 -1.2 -1.0 -1.3 -2.0 -1.8 -1.3 -1.4 2.0 0.5 -0.2 -1.2
Systolic blood pressure, automated reading 0.3 0.8 3.2 1.8 -0.6 -0.2 0.2 0.5 -0.0 -1.5 0.2 0.2 -0.6 0.6 1.4 1.5 0.6
Eye problems/disorders: Diabetes related eye disease 0.3 0.3 1.3 1.0 0.1 0.2 0.9 1.1 0.2 -0.1 0.0 0.4 -0.6 -0.3 -0.7 -0.1 0.1
Angina 0.6 0.8 2.4 0.1 -1.6 -0.3 -0.2 0.9 1.1 -1.2 -0.8 -0.4 -1.0 1.0 1.3 0.8 -0.6
Medication for hormone replacement therapy 1.7 1.9 5.9 -1.5 -0.7 -1.9 -1.0 -0.6 0.3 -1.6 -2.4 -1.8 -1.5 1.2 1.9 -0.2 0.7
Vitamin and mineral supplements 0.7 0.9 2.7 -1.6 0.6 -1.1 -0.9 -0.8 -0.5 -0.3 -1.5 -0.5 -0.6 0.7 0.3 -1.5 -0.8
Supplements: Zinc 0.8 0.9 4.8 -0.3 -2.2 -0.6 -0.9 -1.2 -0.8 -0.7 -0.2 -1.4 -1.2 0.7 -0.4 -0.1 -0.0
Medication: Co-codamol 0.7 0.8 2.5 1.6 0.5 0.9 1.3 1.2 0.3 0.1 1.3 0.9 -0.6 -0.4 -0.1 1.1 0.2
Medication: Metformin 0.2 0.2 0.8 0.9 -0.9 0.3 0.2 0.6 -0.1 -0.4 -0.1 -0.3 -0.2 -0.6 0.4 0.6 0.0
Diabetes (father) 0.9 1.1 3.6 -0.9 -1.3 -1.0 -0.2 -0.3 -1.0 -0.5 -1.4 -1.9 -1.6 0.4 -0.3 -1.3 -0.6
Diabetes (mother) 0.4 0.5 1.9 -0.9 0.8 -0.6 -0.7 -0.7 -0.6 -1.4 -1.3 -0.2 0.2 0.5 0.6 0.0 -0.6
Severe depression (siblings) 0.6 0.6 1.6 0.9 -1.3 -0.2 0.4 1.1 -0.5 0.6 0.7 -0.2 -1.1 -0.6 -1.2 -0.8 0.6
Pack years adult smoking proportion 1.8 2.7 7.6 2.0 0.8 1.5 2.0 2.1 2.8 0.3 1.3 1.9 1.6 -1.2 0.6 2.2 0.8
Impedance of leg (right) 0.2 1.2 3.5 -0.1 -1.0 -0.6 -0.7 -1.2 -1.9 -0.4 0.4 -1.4 -1.3 0.1 -1.7 -1.6 -0.7
Leg fat-free mass (left) 0.5 2.9 9.1 -0.7 2.8 1.1 0.4 1.2 2.3 0.7 -1.1 1.6 2.1 -0.9 3.0 2.0 1.3
Trunk fat percentage 0.2 0.8 4.0 0.1 2.0 0.3 0.7 0.8 1.9 -0.4 -0.8 0.5 0.8 0.5 0.8 0.1 -0.6
Hand grip strength (right) 1.2 3.2 6.9 1.8 1.5 2.6 1.2 1.0 0.9 2.5 1.7 1.4 1.6 -2.3 1.2 2.4 1.8
Townsend deprivation index at recruitment 0.2 0.3 0.9 0.6 -0.3 -0.3 -0.1 0.9 -0.3 -1.0 0.5 -0.0 -0.6 0.5 0.6 -0.2 -0.5
Current tobacco smoking 0.8 1.3 5.9 2.4 0.8 0.9 1.7 1.4 1.4 -0.1 1.3 1.3 0.4 -0.6 -0.2 0.2 -0.1
Average weekly fortified wine intake 0.4 0.5 3.5 -0.3 -0.4 -0.7 0.5 -0.5 -0.3 0.2 -0.1 -0.4 -0.7 -0.1 -1.9 -0.7 0.7
Maternal smoking around birth 2.4 3.4 9.6 1.3 1.6 2.0 1.9 2.5 3.1 1.1 1.7 2.5 1.7 -1.0 0.4 2.5 0.2
Fed-up feelings 2.4 4.4 9.1 -2.5 -1.1 -2.0 -3.0 -2.3 -1.3 -2.0 -2.5 -1.9 -1.2 2.0 2.8 -2.1 -1.4
Frequency of unenthusiasm / disinterest in last 2 weeks 2.0 2.7 5.2 -1.7 -1.1 -1.9 -1.3 -1.3 -0.7 -1.5 -2.3 -1.5 -2.2 2.0 0.5 -1.9 -1.8
Relative age voice broke 0.4 0.6 4.0 0.0 0.4 -0.4 0.8 -0.0 -0.4 -0.7 -0.2 0.0 -0.0 1.1 -1.2 -0.3 -2.0
Taking other prescription medications 0.5 0.8 3.3 0.1 1.0 -0.1 -0.8 -0.3 -0.5 -1.6 0.0 0.2 0.7 1.2 1.1 0.5 -1.8
Age when periods started (menarche) 2.1 5.1 21.3 3.5 0.1 0.2 3.0 2.2 1.9 0.6 3.7 1.3 -0.7 -0.3 -4.6 -0.3 -1.7
Bilateral oophorectomy (both ovaries removed) 0.8 1.0 2.8 -0.8 -1.7 -1.1 -0.8 -1.2 -1.4 -0.2 -0.8 -1.1 -0.5 0.7 -0.4 -1.5 -0.1
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.1 3.6 1.9 -0.2 1.2 1.2 0.7 0.7 1.3 1.7 0.8 0.8 -0.7 -1.2 -0.0 0.3
Tinnitus: Yes, but not now, but have in the past 1.0 1.1 2.7 1.0 0.3 0.7 1.1 1.3 1.4 0.9 0.9 0.8 1.1 -1.2 -0.3 1.6 1.1
Qualifications: CSEs or equivalent 0.7 0.9 3.0 0.5 1.5 0.5 0.6 1.7 1.6 -0.3 0.2 0.9 0.4 -0.5 1.3 -0.4 -0.7
Serious illness, injury or assault to yourself 1.3 1.6 4.4 -1.1 -1.0 -1.4 -1.3 -1.0 -0.5 -1.2 -1.1 -0.9 -2.1 1.7 1.6 -0.2 -1.3
High blood pressure 3.2 9.0 16.7 4.1 2.7 4.0 2.1 2.3 2.0 2.6 3.5 3.6 3.4 -3.2 1.0 3.2 2.6
Hayfever, allergic rhinitis or eczema 7.3 15.9 29.5 -5.0 -0.6 -4.2 -5.2 -4.1 -5.4 -3.8 -4.4 -4.0 -2.7 4.1 2.7 -3.3 -3.8
Multivitamins +/- minerals 0.7 0.8 2.9 1.7 0.0 1.4 0.8 0.5 0.6 0.3 1.7 0.4 0.6 -0.6 -0.2 1.2 0.7
Stomach or abdominal pain in last month 0.8 1.1 3.0 -0.3 0.1 -1.7 -0.3 0.4 0.1 -1.4 -1.1 -0.9 -1.6 1.2 0.4 -1.3 -1.4
Supplements: Glucosamine 6.5 8.5 15.1 3.1 1.3 3.6 2.9 3.0 3.9 2.6 2.9 3.6 3.3 -2.5 0.2 3.6 2.0
Diverticular disease/diverticulitis (self-reported) 2.9 3.5 7.5 2.6 1.7 1.7 2.7 2.7 2.3 1.5 2.0 1.6 1.6 -1.9 -1.0 -0.5 -0.1
Medication: Atenolol 2.4 3.0 7.4 2.3 1.7 2.2 1.8 2.0 2.7 0.2 0.7 1.8 0.9 -1.4 1.4 1.9 1.5
Medication: Levothyroxine sodium 2.4 4.0 7.2 -1.6 -0.8 -2.1 -2.6 -2.5 -2.7 -2.5 -1.8 -2.3 -2.0 2.4 0.6 -1.1 -1.5
Sitting height 0.4 2.7 9.9 -2.1 2.9 1.4 -1.1 -0.5 0.7 1.3 -0.8 1.2 1.8 -0.9 3.1 1.7 0.6
Chronic bronchitis/emphysema (father) 2.4 2.8 6.0 1.9 0.8 1.8 2.3 2.4 2.5 0.3 1.4 1.8 0.9 -1.4 0.0 2.2 1.2
High blood pressure (mother) 0.2 0.3 1.8 -0.2 -0.4 0.4 -0.1 -0.4 0.1 -0.2 -0.0 -0.2 1.4 0.1 0.2 1.4 -0.2
Body mass index (BMI) 0.3 1.3 5.2 0.1 1.0 0.3 0.9 1.1 2.3 -0.3 -1.4 0.8 1.4 0.1 1.6 1.0 1.0
Impedance of leg (left) 0.3 1.3 3.5 -0.1 -0.8 -0.9 -0.6 -1.1 -1.2 -0.5 0.3 -1.3 -1.7 0.6 -1.5 -1.9 -1.6
Leg predicted mass (left) 0.6 3.0 9.3 -0.7 2.8 1.1 0.5 1.3 2.4 0.7 -1.1 1.6 2.2 -1.0 3.0 2.0 1.3
Trunk fat mass 0.3 1.3 5.8 -0.2 2.4 0.4 0.6 0.8 2.2 -0.2 -1.1 0.7 1.2 0.2 1.5 0.4 -0.2
Waist circumference 0.8 2.9 8.4 1.2 2.3 1.4 1.8 2.0 2.9 0.9 0.3 2.0 2.5 -1.4 0.4 1.1 1.0
Number of incorrect matches in round 0.9 1.6 4.9 1.1 0.5 1.8 0.6 0.9 0.7 0.8 1.4 1.2 1.7 -1.0 0.2 2.2 1.6
Past tobacco smoking 0.9 1.7 4.9 -1.5 0.3 -1.2 -2.2 -2.0 -1.7 -0.9 -0.6 -0.7 -0.9 1.3 0.9 -0.7 -1.3
Alcohol usually taken with meals 0.8 1.3 2.9 -1.3 -1.7 -0.9 -1.5 -1.0 -1.2 -0.8 -0.9 -1.3 -1.5 1.3 0.9 0.1 -0.5
Nervous feelings 4.0 7.5 13.0 -2.8 -1.4 -2.7 -3.3 -3.1 -2.8 -2.8 -3.1 -3.6 -2.9 2.5 1.7 -2.8 -2.1
Frequency of tenseness / restlessness in last 2 weeks 2.2 3.4 7.0 -1.9 -1.0 -2.5 -1.4 -1.5 -0.2 -1.9 -2.2 -1.9 -2.1 2.6 0.6 -2.1 -2.2
Hearing difficulty/problems with background noise 2.3 3.7 9.2 -2.5 -1.2 -1.6 -2.6 -3.0 -2.0 -1.0 -2.4 -2.0 -1.5 2.1 1.4 -1.5 -1.1
Hair/balding pattern: Pattern 2 3.9 5.0 10.2 2.5 1.8 2.5 2.6 2.5 2.0 2.4 3.2 3.0 2.3 -1.9 -1.0 1.7 0.4
Had menopause 0.4 0.5 1.6 0.3 -0.5 -0.9 -0.3 -0.6 -0.7 -1.3 -0.6 -0.6 -1.1 0.7 -0.2 -0.1 -0.7
Had other major operations 0.8 1.0 3.3 -0.3 -0.7 -1.1 -0.3 -0.3 0.4 -1.8 -0.9 -0.3 -1.2 1.6 0.6 0.8 -1.7
Forced vital capacity (FVC) 1.6 6.2 11.9 1.9 2.8 3.1 2.5 2.1 2.8 3.5 3.0 2.9 2.8 -2.4 -1.2 1.7 0.3
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.5 2.3 1.2 -1.5 0.1 0.4 -0.0 -0.2 0.6 0.7 -0.7 -0.6 -0.1 -1.2 -0.6 0.3
Ever unenthusiastic/disinterested for a whole week 0.7 0.9 2.3 -0.9 -0.9 -1.1 -0.7 -0.3 -1.0 -1.0 -0.5 -0.6 -1.2 1.2 0.0 -1.3 -1.5
Qualifications: None of the above 0.8 1.6 6.1 2.5 0.1 0.4 1.7 1.2 1.2 0.0 1.8 0.7 0.4 -0.8 -2.4 0.1 0.7
Financial difficulties in last 2 years 0.5 0.6 2.8 0.0 -1.7 -0.8 -0.1 0.3 -0.4 -0.5 -0.8 -1.0 -1.3 0.4 0.3 -0.8 0.5
Mouth/teeth dental problems 1.4 2.2 5.3 0.3 2.1 1.9 0.3 0.4 0.9 0.7 0.3 1.7 2.1 -1.4 1.7 2.3 1.8
Heart attack 2.9 3.8 6.8 2.2 1.2 2.2 2.6 2.6 2.2 1.8 2.0 1.9 1.9 -2.2 -1.0 1.5 0.8
Allergy 7.0 16.2 37.5 4.6 1.9 4.2 5.4 4.1 6.1 3.3 3.8 4.6 2.4 -3.9 -2.6 3.6 3.5
Pain all over the body in last month 0.3 0.3 1.0 0.5 -0.1 -0.1 0.9 0.8 0.5 0.2 0.5 0.7 0.2 0.0 -0.9 -0.5 -1.0
Diabetes (self-reported) 0.4 0.6 4.1 0.4 -2.0 -0.2 0.1 0.5 -0.6 -1.2 -0.7 -0.5 -0.7 0.3 0.1 0.5 -0.1
Hayfever/allergic rhinitis (self-reported) 1.0 1.4 3.4 -1.2 1.0 -0.7 -1.4 -1.2 -1.9 -1.3 -1.4 -0.5 -0.3 1.1 1.8 0.0 -1.0
Medication: Ramipril 1.0 1.3 2.8 1.3 1.7 1.5 -0.1 0.7 0.5 -0.5 0.7 1.5 1.5 -0.1 1.6 1.4 -0.1
Medication: Simvastatin 1.3 1.9 7.0 2.6 -0.3 1.3 1.3 1.7 1.3 0.4 1.7 1.4 0.6 -0.9 -0.7 1.8 1.1
Fluid intelligence score 3.8 8.0 14.2 -3.8 -0.9 -2.8 -3.4 -3.4 -3.5 -2.5 -3.5 -3.3 -2.9 2.6 1.2 -1.6 -2.3
Illnesses of siblings 2.6 3.6 8.5 -2.6 -0.6 -2.4 -1.7 -1.9 -1.5 -1.2 -1.5 -2.1 -1.7 1.9 -0.9 -2.9 -2.2
Neuroticism score 5.6 11.7 18.8 -3.8 -2.1 -3.9 -3.7 -3.5 -2.7 -3.7 -4.3 -4.3 -3.5 3.3 2.0 -3.6 -2.3
Weight 0.5 2.2 6.7 -0.7 2.6 0.6 0.5 0.9 2.5 0.3 -1.5 1.2 1.8 -0.4 2.5 1.4 0.9
Impedance of arm (right) 0.2 0.9 3.3 0.1 0.2 0.6 -0.1 -0.0 -1.4 -0.2 1.6 -0.5 -0.5 0.1 -1.6 -1.0 -1.8
Arm fat percentage (right) 0.2 0.8 2.9 0.1 1.2 0.7 0.9 0.9 1.7 -0.4 -1.0 0.4 1.4 0.4 0.9 0.4 -0.0
Trunk fat-free mass 0.5 3.1 8.5 -0.6 2.7 1.0 0.4 1.0 2.2 1.2 -0.8 1.9 2.2 -1.3 2.9 2.2 1.8
Hip circumference 0.2 1.1 4.2 -0.3 1.7 0.4 0.2 0.9 1.8 0.1 -1.1 0.8 0.8 -0.0 2.0 0.8 0.5
Time employed in main current job 0.6 0.7 3.5 -0.6 0.8 0.2 -0.5 -1.4 -0.4 0.1 -0.4 -0.1 0.6 -0.1 0.8 1.3 1.9
Alcohol intake versus 10 years previously 0.7 1.1 3.3 0.2 1.8 0.5 0.9 1.3 1.8 0.1 1.0 1.6 0.9 -0.1 0.3 -0.3 -1.2
Father’s age at death 1.7 2.3 5.3 -2.3 -0.3 -2.3 -1.0 -1.2 -1.2 -0.7 -1.4 -1.1 -1.1 1.7 -1.5 -2.0 -2.1
Worrier / anxious feelings 5.7 10.8 17.4 -3.8 -2.8 -3.7 -4.2 -3.8 -3.6 -3.3 -3.4 -3.7 -3.1 2.9 0.4 -3.5 -1.9
Frequency of tiredness / lethargy in last 2 weeks 2.3 3.8 6.9 -1.4 -2.1 -2.4 -1.7 -1.4 -1.8 -2.2 -1.9 -2.4 -2.6 2.3 0.5 -2.0 -1.5
Falls in the last year 0.4 0.6 1.7 0.9 0.9 0.3 0.8 0.8 1.2 -0.8 0.6 1.3 0.6 0.1 0.0 0.2 -0.9
Hair/balding pattern: Pattern 3 2.5 3.8 7.2 -1.1 -1.3 -2.1 -1.9 -2.0 -1.4 -2.4 -1.5 -2.2 -1.9 2.6 0.2 -2.2 -2.7
Number of live births 0.7 1.0 2.7 1.2 -0.4 1.5 0.9 0.4 1.5 0.7 1.4 0.9 0.1 -0.1 0.3 1.6 0.9
Forced expiratory volume in 1-second (FEV1) 0.3 1.0 3.2 -0.8 1.4 0.6 0.6 0.1 1.2 1.8 0.5 0.7 1.1 -0.4 -1.2 -0.4 -1.3
Pulse rate 0.2 0.3 0.8 -0.3 -0.3 0.1 -0.9 -0.8 -0.6 -0.3 0.1 -0.5 0.6 0.0 0.7 0.7 0.6
Happiness 2.5 3.1 11.5 -1.3 -0.7 -1.8 -1.0 -0.8 -0.8 -1.4 -1.1 -1.5 -2.0 2.1 0.5 -3.1 -3.4
Noisy workplace 1.3 1.6 4.6 1.7 -0.5 1.8 1.4 1.2 0.1 0.8 2.1 1.6 1.5 -0.4 -1.0 0.5 -1.0
Qualifications: A levels/AS levels or equivalent 2.5 5.6 10.4 -3.0 -2.5 -1.9 -2.5 -2.5 -2.0 -2.6 -3.2 -2.4 -2.5 3.2 1.2 0.4 -1.2
Serious illness, injury or assault of a close relative in last 2 years 1.2 1.4 8.7 -0.0 -1.4 0.6 0.5 0.2 0.2 1.5 -0.3 -0.0 1.0 -0.7 0.3 2.2 3.0
Mouth/teeth dental problems: Dentures 1.0 1.6 5.0 1.8 -0.3 -0.3 1.4 1.5 0.6 -0.8 1.8 0.7 -0.8 0.3 -2.2 -0.9 -2.0
Asthma 1.0 2.0 7.5 -1.4 -1.5 -0.8 -2.2 -1.2 -2.7 -0.7 -0.5 -1.6 0.1 1.2 1.0 -1.3 -1.3
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.6 2.6 -0.7 1.3 0.1 -0.4 0.0 0.8 -0.3 -0.6 0.3 0.4 0.3 1.6 -0.6 -1.4
Medication: Cholesterol lowering 1.3 2.0 5.2 2.3 0.4 1.0 1.6 2.2 1.6 0.7 2.0 1.4 0.9 -1.4 -1.3 0.4 -0.2
Depression (self-reported) 2.1 2.5 7.8 -1.7 -1.4 -0.8 -1.9 -1.9 -2.8 -0.9 -2.1 -2.0 -1.8 0.5 1.2 -1.0 0.0
Medication: Lansoprazole 1.7 2.0 7.6 1.5 -0.4 0.1 2.1 2.8 1.7 1.2 1.0 0.9 0.9 -1.6 -1.8 -0.3 0.1
Prospective memory result 2.0 2.4 6.8 1.4 2.6 1.1 2.0 2.0 1.6 1.1 1.7 2.3 1.3 -0.8 -1.0 0.4 -0.7
Lung cancer (father) 0.4 0.4 2.1 0.5 0.1 0.3 0.1 0.3 1.1 -0.3 -0.2 0.1 -1.1 0.3 0.8 1.4 0.2
Illnesses of mother 0.6 0.7 1.9 0.6 1.1 0.3 -0.1 0.3 1.0 1.3 1.0 0.7 -0.3 -1.2 0.1 -0.8 1.4
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.8 3.0 -0.8 1.7 0.3 0.5 0.0 1.4 1.3 0.3 0.6 0.7 -0.3 -0.9 0.0 -0.9
Pulse wave Arterial Stiffness index 1.9 2.2 5.0 -1.6 -0.9 -1.8 -1.4 -1.3 -0.6 -1.5 -2.0 -1.4 -2.2 2.1 0.9 -0.9 -1.0
Impedance of arm (left) 0.3 1.2 3.3 -0.2 -0.1 -0.2 -0.8 -0.7 -1.8 -0.4 1.2 -1.2 -1.2 0.4 -1.7 -1.7 -1.5
Arm fat mass (right) 0.4 1.5 5.4 -0.0 1.9 0.7 0.9 1.0 2.3 0.0 -1.1 1.0 1.7 0.0 1.8 1.0 0.5
Trunk predicted mass 0.5 3.0 8.7 -0.7 2.5 0.9 0.3 1.0 2.1 1.1 -0.9 1.8 2.1 -1.3 3.0 2.1 1.9
Standing height 0.2 2.0 13.6 -1.9 3.7 0.6 -0.8 -0.3 0.6 1.3 -0.4 0.8 1.0 -1.2 2.0 0.7 -0.1
Length of working week for main job 0.4 0.4 0.9 0.2 -0.5 0.3 0.9 0.9 0.4 0.4 0.8 0.6 0.8 -0.4 -0.9 0.8 0.1
Exposure to tobacco smoke at home 1.1 1.2 2.8 1.7 0.4 0.9 1.4 1.6 0.8 1.2 1.6 1.3 0.5 -1.3 0.2 0.4 0.1
Breastfed as a baby 0.4 0.5 2.1 -0.3 -0.6 0.0 -0.7 -1.1 -0.6 0.9 -0.4 -0.7 -0.1 -0.6 0.2 -0.3 1.5
Tense / ‘highly strung’ 2.3 3.9 7.0 -2.4 -1.8 -2.3 -2.6 -2.4 -1.5 -1.6 -2.6 -2.5 -1.6 1.9 1.0 -1.4 -0.3
Seen doctor (GP) for nerves, anxiety, tension or depression 5.1 7.7 11.4 -3.1 -1.6 -3.3 -2.7 -2.3 -2.3 -3.1 -3.0 -3.1 -3.2 2.9 0.7 -3.4 -2.9
Hair/balding pattern: Pattern 4 3.7 9.0 17.9 3.0 2.2 3.6 3.3 3.7 3.6 1.6 2.6 3.8 3.7 -2.1 -0.3 4.2 1.8
Birth weight of first child 0.6 1.1 2.9 -1.0 1.7 -0.5 -0.9 -0.7 1.5 -0.2 -0.2 0.5 -0.0 1.2 1.6 0.6 -1.6
Peak expiratory flow (PEF) 0.6 1.3 5.7 -2.4 -1.0 -1.0 -1.3 -1.0 -0.3 0.7 -1.4 -1.5 -0.6 -0.1 0.4 -1.4 -0.7
Pulse wave reflection index 1.1 1.3 5.9 -0.8 -1.4 -1.1 -0.4 -0.7 -0.9 -0.8 -1.4 -0.9 -2.4 1.3 -0.1 -1.0 -1.0
Ever highly irritable/argumentative for 2 days 0.5 0.6 1.3 -0.7 -1.1 -0.8 -0.5 -0.9 -1.1 -0.3 -0.8 -1.1 -0.8 0.2 -0.6 -1.2 -0.1
Loud music exposure frequency 1.6 1.8 4.7 -1.9 -1.2 -1.6 -1.4 -1.3 -1.6 -0.6 -1.5 -1.5 -1.0 0.6 -0.1 -2.2 -0.5
Qualifications: O levels/GCSEs or equivalent 0.3 0.5 1.9 -1.4 -0.3 -0.9 -0.5 -0.3 0.2 -0.0 -1.1 -0.4 -0.6 0.7 0.6 0.0 -1.1
Mouth/teeth dental problems: Bleeding gums 0.3 0.4 1.3 -0.6 -0.7 -0.3 -0.7 -0.9 -0.3 1.1 -0.2 -0.5 -0.8 -0.3 -0.1 -1.2 0.5
Blood clot in the leg (DVT) 0.8 1.1 3.7 -0.3 -0.9 -1.6 -1.3 -0.8 -1.1 -0.3 -0.5 -1.2 -1.4 0.5 0.2 -1.9 -0.3
Medication: Paracetamol 0.5 0.8 1.5 1.0 1.1 1.1 1.0 0.5 0.9 0.3 0.8 0.9 1.2 -1.2 -0.9 0.6 0.9
Headache pain in last month 0.2 0.3 1.0 -0.7 0.6 0.3 0.3 0.4 0.5 0.0 -0.6 -0.3 1.0 0.3 -0.1 -0.8 -0.3
Medication for cholesterol, blood pressure or diabetes 3.6 6.0 12.0 -3.5 -1.5 -2.9 -2.3 -2.9 -2.6 -2.0 -2.8 -2.9 -2.3 2.9 0.0 -2.2 -1.7
Glaucoma (self-reported) 1.5 1.7 5.5 2.3 0.7 1.3 1.2 1.2 1.0 0.4 2.1 1.9 1.0 -0.6 -0.9 1.4 0.6
Gout (self-reported) 5.7 7.8 16.1 4.0 1.7 3.1 2.9 3.5 4.0 1.5 3.5 3.5 2.4 -2.4 -0.4 2.3 0.5
Hypothyroidism/myxoedema (self-reported) 1.6 3.2 6.9 -1.7 -0.4 -2.1 -2.4 -2.1 -2.1 -2.3 -1.7 -1.8 -1.2 2.6 0.8 -0.5 -1.5
Medication: Amlodipine 6.4 9.0 15.7 3.0 1.2 4.0 2.7 3.0 2.9 3.5 3.1 3.0 3.6 -3.6 -0.0 2.9 3.3
Medication: Ventolin 100micrograms inhaler 1.2 1.6 3.7 -1.2 -1.0 -0.9 -1.9 -1.4 -1.7 -0.8 -0.8 -1.6 -1.3 1.2 1.5 -1.0 -0.7
Birth weight 0.3 0.7 4.8 -0.2 1.6 -0.0 0.1 0.5 0.9 -0.2 0.2 0.6 -0.1 0.4 0.5 -0.4 -2.2
Chronic bronchitis/emphysema (mother) 0.6 0.7 1.7 -0.8 0.2 -0.4 -0.8 -0.7 -0.9 -1.2 -1.3 -0.8 -0.4 0.8 1.3 0.8 0.4
High blood pressure (siblings) 3.9 5.6 8.9 2.8 1.0 3.0 2.3 2.5 2.5 2.3 2.0 2.7 2.3 -2.4 0.5 3.0 2.5
Forced vital capacity (FVC), Best measure 1.7 6.3 11.7 1.8 3.1 3.0 2.5 2.1 3.0 3.4 2.9 2.9 2.7 -2.5 -1.0 2.0 0.7
Body fat percentage 0.2 0.7 2.5 -0.2 1.4 -0.1 0.6 0.5 1.6 -0.7 -1.3 0.1 0.6 0.8 0.7 -0.3 -0.5
Leg fat percentage (right) 0.1 0.5 2.4 -0.2 0.6 -0.2 0.6 0.2 1.3 -0.5 -1.6 -0.1 0.8 0.5 0.5 -0.4 0.2
Arm fat-free mass (right) 0.4 2.0 7.8 -0.7 2.1 0.2 0.1 0.7 2.1 0.4 -1.5 1.2 1.2 -0.6 2.8 1.6 1.4
Exposure to tobacco smoke outside home 0.6 0.8 1.6 0.8 0.7 1.2 1.2 1.3 0.6 0.2 1.0 1.2 1.3 -0.5 0.6 -0.2 -1.1
Comparative body size at age 10 4.0 11.0 27.8 1.9 1.7 4.0 2.1 2.9 3.3 2.4 2.5 4.2 4.9 -3.1 1.7 5.3 3.9
Number of full brothers 0.5 0.6 2.4 1.1 0.7 -0.4 0.8 1.6 1.3 -0.4 0.0 0.5 -0.5 -0.4 0.7 0.4 0.5
Worry too long after embarrassment 4.2 7.1 12.5 -2.7 -0.5 -3.1 -2.8 -2.7 -2.2 -3.1 -2.8 -3.5 -2.5 2.9 0.9 -3.1 -2.7
Seen a psychiatrist for nerves, anxiety, tension or depression 3.9 5.0 11.5 -2.7 -1.3 -2.8 -1.7 -1.4 -1.3 -2.4 -2.4 -2.1 -2.3 2.6 0.6 -2.8 -3.4
Wheeze or whistling in the chest in last year 0.1 0.1 0.3 -0.1 -0.5 -0.4 0.1 0.3 0.2 0.1 -0.5 0.0 0.5 0.2 0.4 -0.3 0.2
Number of children fathered 1.1 1.2 4.5 -1.4 -1.0 -1.5 -0.7 -0.7 0.2 0.4 -1.2 -1.3 -1.5 0.3 -0.5 -2.1 -0.7
Reason for reducing amount of alcohol drunk: Health precaution 0.8 1.0 5.0 0.5 0.7 0.3 0.5 0.8 1.1 -0.2 -0.7 0.3 0.9 -0.3 1.8 2.2 1.0
Age at first live birth 2.6 4.7 8.7 -2.9 -2.1 -2.4 -1.6 -2.0 -2.4 -1.8 -2.8 -2.4 -2.5 2.4 0.4 -0.9 -2.2
Pulse wave peak to peak time 1.7 2.0 4.4 1.4 1.1 1.6 1.3 1.3 0.7 1.4 1.9 1.3 2.1 -2.1 -0.7 0.9 0.9
Health satisfaction 1.2 1.6 4.5 -0.3 0.5 -0.9 -0.5 0.2 0.4 -2.1 -1.3 -0.6 -1.1 2.1 2.1 -0.0 -2.0
Shortness of breath walking on level ground 0.8 0.9 4.4 1.4 -0.6 0.9 1.0 1.0 0.7 0.0 0.6 0.6 0.8 -0.1 0.8 2.1 0.7
Qualifications: College or University degree 1.6 5.1 11.5 -3.4 -1.9 -1.5 -2.9 -3.0 -3.1 -1.7 -2.8 -2.4 -1.5 2.5 0.7 -0.0 -1.2
Eye problems/disorders: None of the above 0.5 0.5 3.3 -0.4 0.2 0.5 0.4 -0.1 0.8 1.8 0.4 0.2 1.0 -1.2 -0.4 -0.6 0.3
Mouth/teeth dental problems: Loose teeth 0.8 1.0 3.0 1.0 1.4 0.7 1.2 1.1 1.7 -0.9 0.5 1.1 0.7 -0.0 -0.4 0.9 -0.7
Emphysema/chronic bronchitis 2.3 2.6 7.2 -1.1 -2.7 -1.6 -1.8 -1.6 -1.6 -1.5 -1.6 -2.0 -1.8 1.6 1.3 0.4 0.6
Medication for pain relief, constipation, heartburn 1.0 1.7 2.9 -1.6 -1.6 -1.3 -1.4 -1.5 -1.4 -0.4 -1.3 -1.5 -1.6 1.7 0.8 0.3 0.1
Neck or shoulder pain in last month 1.9 2.8 6.0 1.8 1.4 2.4 1.7 1.8 1.4 1.6 1.8 1.5 1.6 -2.0 0.4 1.2 1.6
Medication: Blood pressure 4.1 7.2 13.4 2.9 2.5 3.7 2.2 2.8 2.5 2.2 2.6 3.4 3.2 -3.3 1.1 2.4 1.7
Angina (self-reported) 0.6 0.8 2.1 0.4 -1.4 -0.0 -0.0 1.1 1.3 -1.0 -0.6 -0.1 -0.8 0.8 1.4 1.0 -0.3
Migraine (self-reported) 2.6 3.2 6.3 1.7 1.8 2.3 1.6 2.2 1.9 1.4 1.6 2.5 2.4 -1.4 0.8 1.7 0.6
Medication: Ibuprofen 0.8 0.9 3.7 -1.5 0.6 -0.2 -1.1 -0.8 -0.2 -0.3 -1.3 -0.6 -0.2 0.5 1.9 -0.9 -1.2
Medication: Allopurinol 5.4 7.2 14.1 3.8 2.0 2.9 3.3 3.5 3.5 1.8 3.0 3.1 1.9 -2.5 -0.6 2.6 0.9
Medication: Omeprazole 0.3 0.3 2.5 0.2 0.7 0.5 -0.0 -0.2 -0.2 -0.3 0.8 0.4 1.6 -0.2 -0.0 -0.1 0.4
Medication: Seretide 50 evohaler 1.2 1.4 8.1 0.2 -2.9 -0.6 -1.0 -0.5 -1.6 -1.1 -0.3 -0.9 -1.5 1.1 1.1 0.2 0.5
Mean time to correctly identify matches 1.4 2.7 5.4 2.3 1.3 1.8 2.3 2.1 1.9 0.8 2.1 2.2 1.1 -1.1 -0.7 1.0 0.9
Heart disease (mother) 0.3 0.4 1.4 0.8 -0.5 0.5 0.8 0.8 0.4 -0.4 0.4 0.6 0.5 0.6 0.2 1.2 -0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.0 1.2 5.8 1.0 2.4 0.9 1.2 1.3 1.2 -0.4 0.7 1.3 0.7 -0.9 0.3 0.7 -0.0
Whole body fat mass 0.3 1.2 4.8 -0.3 2.0 0.2 0.6 0.8 2.2 -0.5 -1.4 0.6 1.1 0.4 1.6 0.5 -0.2
Leg fat mass (right) 0.2 1.0 3.9 -0.6 1.1 -0.2 0.5 0.6 1.9 -0.7 -2.0 0.1 0.9 0.5 1.5 0.2 -0.1
Arm predicted mass (right) 0.5 2.6 7.3 -0.4 2.6 0.6 0.5 1.0 2.5 0.8 -1.2 1.7 1.6 -1.0 2.7 2.0 1.6
Pulse rate, automated reading 0.1 0.3 1.3 -0.5 -0.7 -0.0 -0.8 -0.6 -0.2 -0.3 0.1 -0.2 0.9 0.2 0.7 1.1 0.5
Alcohol intake frequency. 1.2 2.9 6.6 -2.6 1.3 -1.6 -1.4 -1.7 -0.5 -2.1 -2.3 -0.7 0.6 2.5 0.5 -1.3 -2.2
Comparative height size at age 10 1.0 5.3 12.5 0.5 3.5 2.6 0.2 1.0 1.1 2.9 0.9 2.3 3.2 -3.1 3.1 1.8 2.2
Number of full sisters 0.6 0.8 2.1 0.1 0.8 0.3 1.0 1.4 1.3 0.9 -0.2 0.9 0.8 -0.9 0.3 0.6 1.5
Suffer from ‘nerves’ 5.1 8.0 14.1 -3.5 -0.9 -2.8 -3.1 -3.2 -2.8 -2.5 -3.8 -3.5 -2.8 2.4 1.6 -3.1 -1.8
Overall health rating 0.8 1.8 7.2 -0.1 -1.3 -1.7 -0.2 0.6 -0.2 -2.7 -1.6 -0.9 -1.1 2.1 1.0 -0.7 -1.7
Chest pain or discomfort 1.4 2.0 4.4 -1.0 -2.0 -1.3 -0.9 -0.4 -1.4 -1.9 -1.4 -1.3 -2.1 1.9 0.9 -0.6 -1.5
Had major operations 1.6 1.9 4.4 1.3 0.2 1.1 1.6 1.3 1.3 2.1 1.9 1.5 0.9 -1.5 -2.0 0.1 0.4
Age at last live birth 2.5 3.6 8.1 -2.9 -1.8 -1.6 -1.8 -2.0 -1.8 -1.8 -2.5 -2.0 -1.8 2.4 1.0 -0.1 -1.7
Family relationship satisfaction 1.6 1.9 5.4 -1.5 0.0 -1.7 -0.4 -0.3 -0.1 -0.9 -1.6 -0.9 -1.8 2.1 0.6 -2.0 -2.3
Leg pain on walking 0.9 1.1 4.4 -0.7 -0.6 -1.4 -0.5 -0.7 -0.1 -0.5 -1.0 -0.9 -2.1 0.9 -0.7 -1.7 -1.2
Qualifications: NVQ or HND or HNC or equivalent 0.5 0.6 1.9 -0.8 0.4 -1.0 -0.3 0.1 0.8 -1.4 -1.3 0.1 -0.2 1.1 1.2 -0.1 -0.4
Commuting to job workplace: Car/motor vehicle 1.0 1.2 3.5 0.8 1.3 1.6 0.9 0.7 1.2 0.9 0.6 1.2 1.3 -0.6 0.6 1.9 0.5
Illness, injury, bereavement, stress in last 2 years 1.8 2.2 7.8 1.4 2.8 1.2 1.3 1.1 1.5 0.7 1.9 1.7 1.9 -1.1 -1.7 0.3 -0.5
Medication: Aspirin 0.9 1.2 3.0 1.5 0.9 0.8 1.6 1.7 1.0 0.2 1.1 1.3 0.5 -1.2 -1.4 -0.1 -0.0
Supplements: Vitamin C 0.5 0.6 2.2 -0.4 -0.7 -0.7 -0.7 -0.3 -0.1 -1.5 -1.2 -0.6 -0.8 0.8 0.9 0.8 0.1
Knee pain experienced in last month 2.4 3.8 11.0 2.3 1.6 1.7 2.6 2.5 3.3 0.8 2.3 2.6 1.3 -0.5 -1.2 1.4 0.3
Hypertension (Self-reported) 2.5 6.9 12.1 3.5 2.4 3.4 1.7 1.8 1.9 2.3 2.9 3.1 3.2 -3.0 1.0 2.7 2.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.3 0.3 0.9 -0.9 -0.1 0.2 -0.6 -0.9 -0.3 -0.0 -0.9 -0.2 0.8 0.3 0.7 -0.2 -0.3
Illnesses of father: Heart disease 0.6 0.8 2.6 1.1 0.4 1.4 0.9 0.8 -0.1 -0.3 0.4 0.9 0.9 -0.7 0.5 1.6 1.0
Illnesses of siblings: Diabetes 0.6 0.7 2.1 -0.2 -1.4 -1.2 -0.7 -0.8 -0.9 -1.4 -0.9 -0.3 -0.9 0.5 0.1 -0.0 0.4
Smoking status: Previous 1.1 1.7 3.8 1.1 -0.1 1.5 2.0 1.8 1.5 1.1 0.7 0.8 1.0 -1.6 -1.1 1.0 1.6
Forced expiratory volume in 1-second (FEV1), predicted 0.4 0.9 7.3 -0.6 2.7 0.6 0.0 -0.0 0.6 0.7 0.2 0.8 0.9 -0.7 0.9 0.4 -0.1
Whole body fat-free mass 0.6 3.5 9.6 -0.5 2.9 1.1 0.5 1.2 2.5 1.1 -0.9 2.0 2.2 -1.3 3.1 2.4 1.7
Leg fat-free mass (right) 0.5 2.9 9.8 -0.6 2.8 1.1 0.5 1.2 2.4 0.7 -0.9 1.8 1.9 -0.8 3.1 2.1 1.0
Arm fat percentage (left) 0.1 0.5 1.9 -0.1 1.0 0.2 0.5 0.5 1.4 -0.6 -1.2 0.1 1.0 0.6 0.7 -0.1 0.0
Average weekly red wine intake 0.4 0.6 3.5 0.0 -1.9 0.0 -0.5 -0.3 -0.6 0.5 -0.2 -0.9 -0.7 -0.6 0.2 0.5 1.4
Handedness (chirality/laterality): Left-handed 2.1 2.5 6.3 -2.5 0.2 -1.4 -1.6 -1.5 -0.5 -1.2 -2.1 -0.9 -0.8 2.4 1.8 -1.4 -2.0
Mood swings 1.6 2.8 6.9 -1.3 -1.3 -2.0 -1.1 -1.3 -1.5 -2.1 -1.8 -2.0 -1.6 1.8 0.1 -2.6 -1.7
Loneliness, isolation 2.2 3.1 7.3 -2.0 -1.6 -2.3 -1.3 -1.1 -0.3 -1.9 -2.7 -2.4 -2.5 1.6 1.0 -1.3 -0.3
Long-standing illness, disability or infirmity 1.2 1.8 7.1 -0.6 -0.7 -1.7 -0.5 0.1 -0.9 -2.7 -0.7 -0.7 -1.7 2.0 -0.4 -1.0 -2.0
Ever had bowel cancer screening 0.4 0.4 1.7 -0.4 -0.5 -0.8 -0.1 -0.2 -1.1 -0.4 -0.1 -0.9 0.0 0.5 -0.5 -0.7 -1.3
Diabetes diagnosed by doctor 0.3 0.5 1.9 0.5 -1.2 -0.2 -0.2 0.0 -0.1 -1.4 -0.8 -0.5 -0.8 0.5 0.4 0.9 0.1
Ever had stillbirth, spontaneous miscarriage or termination 1.3 1.4 4.5 -0.7 -2.1 -1.5 -0.4 -0.7 -0.6 -1.7 -1.4 -1.6 -0.3 1.3 -0.1 -1.3 -0.6
Friendships satisfaction 2.2 2.7 9.0 -1.9 -0.7 -1.8 -1.5 -1.2 0.2 -1.6 -2.0 -1.1 -1.7 3.0 1.5 -0.6 -2.0
Qualifications: nursing, teaching 1.7 2.6 7.8 -2.8 -1.0 -1.6 -1.4 -1.7 -1.1 -1.1 -1.7 -1.8 -1.6 2.2 -0.1 -0.8 -1.8
Commuting to job workplace: Walk 0.3 0.3 1.3 -0.0 0.6 0.3 0.3 0.2 0.8 -0.0 0.7 1.0 0.6 0.3 -1.1 -0.3 -0.7
Eye problems/disorders: Cataract 0.4 0.5 2.1 -0.4 -0.3 -0.0 -0.7 -0.3 -0.3 -1.4 -0.7 -0.2 -0.3 0.9 0.8 1.2 -0.3
Mouth/teeth dental problems: Mouth ulcers 1.3 2.0 4.8 -1.3 -1.7 -1.8 -0.5 -0.7 -1.1 -1.0 -1.6 -2.2 -1.8 1.8 -0.5 -1.1 -1.5
Medication for cholesterol 1.4 2.1 7.2 -1.9 -0.7 -1.3 -0.8 -1.1 -1.7 -0.5 -0.6 -1.1 -0.7 1.3 -1.8 -2.0 -2.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.1 0.1 0.4 0.1 0.4 -0.4 -0.3 0.2 0.3 0.6 0.1 0.2 -0.5 -0.3 0.1 -0.2 -0.1
Back pain experienced in last month 1.8 2.6 7.1 2.1 -0.3 1.7 2.5 1.8 1.0 0.9 0.6 1.0 1.3 -1.7 -1.0 2.7 1.7
Mineral and other dietary supplements 2.7 3.6 6.7 -2.2 0.3 -2.3 -2.6 -2.3 -2.3 -1.8 -1.7 -1.6 -1.7 1.8 0.4 -2.0 -1.9
Breast cancer (self-reported) 0.3 0.3 1.1 -0.3 -0.5 -0.4 -0.1 -0.4 -0.9 -0.1 -0.2 -0.5 -0.8 0.6 -0.7 -0.4 -1.1
Asthma (self-reported) 0.9 1.8 7.6 -1.3 -1.5 -0.8 -2.1 -1.1 -2.8 -0.7 -0.5 -1.6 0.1 1.1 0.9 -1.2 -0.9
Osteoporosis (self-reported) 0.6 0.8 2.0 -0.9 -0.5 -1.0 -0.6 -1.1 -1.0 -1.1 -1.0 -1.1 -0.8 1.4 -0.0 0.0 -0.8
Osteoarthritis (self-reported) 1.7 2.2 5.3 1.5 0.7 1.2 1.8 2.3 2.2 -0.2 1.2 2.3 1.5 -0.2 0.3 1.9 -0.0
Medication: Aspirin 0.9 1.2 2.6 1.5 1.1 1.1 1.4 1.6 1.1 0.1 1.2 1.4 0.6 -1.1 -0.8 0.5 -0.0
Medication: Gliclazide 0.1 0.1 0.5 0.1 -0.7 -0.0 0.3 0.3 -0.1 0.4 -0.7 -0.7 -0.2 -0.3 0.2 -0.1 0.2
Illnesses of father: None of the above (group 1) 0.4 0.5 1.4 0.3 0.7 0.1 0.3 0.8 1.0 1.1 1.2 1.1 1.0 -0.3 -0.3 0.0 -0.4
Smoking status: Current 0.7 1.1 5.4 2.3 0.5 0.7 1.6 1.3 1.2 0.0 1.4 1.2 0.5 -0.5 -0.3 -0.2 -0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.7 1.4 4.7 -0.2 1.6 0.5 1.2 0.7 1.5 2.2 1.1 1.2 0.8 -0.7 -2.0 -0.2 -0.8
Whole body water mass 0.6 3.5 9.0 -0.4 2.9 1.2 0.6 1.3 2.5 1.1 -0.8 2.0 2.3 -1.3 3.0 2.4 1.7
Leg predicted mass (right) 0.5 2.9 9.5 -0.6 2.8 1.1 0.5 1.3 2.5 0.7 -1.0 1.8 1.9 -0.8 3.1 2.1 0.9
Arm fat mass (left) 0.3 1.2 4.5 -0.2 1.7 0.5 0.6 0.8 2.1 -0.2 -1.3 0.7 1.4 0.1 1.8 0.8 0.6
Number of self-reported non-cancer illnesses 0.4 0.7 4.1 0.3 0.6 0.1 -1.0 -0.3 -0.9 -1.4 -0.2 -0.0 0.3 0.8 2.0 0.8 -0.3
Average weekly champagne plus white wine intake 0.9 1.2 3.5 -1.9 -0.4 -0.4 -1.1 -1.6 -1.5 -0.4 -1.0 -1.2 -0.4 1.2 -0.2 -0.7 -1.3
Miserableness 4.6 8.0 14.7 -2.7 -2.7 -3.1 -3.1 -2.8 -2.4 -2.6 -2.8 -3.5 -3.8 2.6 1.1 -3.3 -2.1
Guilty feelings 2.9 4.4 9.7 -2.7 -1.9 -2.5 -1.9 -2.3 -1.4 -1.3 -2.3 -2.5 -2.3 1.8 0.1 -3.1 -1.4
Wears glasses or contact lenses 0.3 0.3 1.9 -0.9 0.1 0.2 0.2 0.1 -0.4 0.8 -0.3 -0.1 -0.2 0.0 -1.4 -0.5 -0.3
Ever taken oral contraceptive pill 0.3 0.3 1.5 -0.8 -0.6 -0.0 -0.5 -0.3 -0.1 -0.6 -0.7 -0.1 -0.2 0.7 1.2 0.6 0.5
Hearing aid user 1.6 1.9 3.7 -1.8 -1.6 -1.4 -1.8 -1.7 -1.4 -0.7 -1.9 -1.6 -1.4 0.9 0.3 -1.1 0.2
Mother’s age at death 2.6 3.2 8.1 -1.9 -2.4 -2.6 -1.0 -1.3 -1.4 -0.8 -1.4 -1.7 -2.8 1.8 -0.9 -2.2 -1.4
Financial situation satisfaction 1.4 1.8 5.1 -1.0 -0.7 -0.9 -0.9 -0.2 0.4 -1.5 -1.7 -0.2 -1.7 1.9 2.3 -1.4 -1.7
Tinnitus: Yes, now most or all of the time 0.6 0.7 2.0 -0.8 0.4 -0.8 -0.7 -1.4 -0.6 -0.8 -1.1 -1.2 -1.1 0.6 -0.4 -0.8 -0.3
Commuting to job workplace: Public transport 0.5 0.6 4.0 -0.7 -2.0 -1.0 -0.5 -0.4 -0.7 -0.5 -0.4 -0.5 -0.4 0.3 -0.2 -0.8 0.2
Eye problems/disorders: Glaucoma 1.2 1.4 5.6 2.4 -0.1 1.1 1.0 1.2 1.2 0.0 1.4 1.3 0.3 -0.2 -0.3 1.9 1.2
Medication: Blood pressure 2.7 5.1 9.7 3.1 1.8 2.7 1.6 1.8 2.3 1.6 2.5 2.5 2.1 -2.0 1.3 2.9 2.5
Pain type(s) experienced in last month: Hip pain 0.7 0.9 3.3 0.5 -0.3 0.7 0.8 0.8 1.1 -0.1 0.1 0.9 0.7 -0.0 1.1 1.7 1.8
Supplements: Fish oil (including cod liver oil) 4.0 5.2 10.2 2.1 1.4 2.6 2.8 2.4 3.2 2.0 1.7 2.5 3.2 -2.0 -0.6 2.1 1.6
High cholesterol (Self-reported) 1.9 3.4 10.2 3.2 0.5 2.2 1.7 1.9 1.9 0.4 2.5 2.3 0.9 -1.0 -0.2 2.7 1.2
Medication: Bendroflumethiazide 1.9 2.8 7.6 1.9 1.0 1.9 0.9 1.0 1.5 1.2 1.4 1.8 1.7 -1.4 1.5 2.5 2.8
Medication: Paracetamol 0.4 0.6 1.9 0.6 0.6 0.9 0.7 0.2 0.2 0.6 0.6 0.4 1.0 -1.4 -1.3 0.2 1.2
Medication: Lisinopril 1.0 1.3 2.6 1.4 -0.8 1.2 1.6 1.5 1.1 1.3 1.3 0.6 0.4 -1.2 -0.8 1.0 1.0
Medication: Atorvastatin 0.1 0.2 0.4 0.6 0.2 0.3 0.6 0.7 0.1 0.2 0.4 0.3 0.1 -0.5 -0.1 -0.5 -0.3
Illnesses of father: High blood pressure 1.0 1.3 3.8 1.6 -0.9 1.3 0.8 0.4 -0.0 1.2 1.1 0.6 1.3 -1.2 -0.1 1.3 2.0
Alcohol drinker status: Never 0.8 1.0 4.1 -0.5 2.0 -0.1 -0.2 -0.6 0.9 -1.1 -0.7 0.3 0.8 1.5 0.1 0.7 -1.8
Ever smoked 0.2 0.3 1.2 0.7 -0.7 0.2 1.1 0.8 0.5 -0.2 -0.5 -0.5 -0.2 -0.1 -0.3 0.1 0.6
Basal metabolic rate 0.6 3.2 9.3 -0.6 2.9 1.0 0.5 1.2 2.5 0.9 -1.1 1.9 2.2 -1.0 3.0 2.1 1.4
Leg fat percentage (left) 0.2 0.7 2.9 -0.3 0.7 -0.4 0.6 0.3 1.7 -0.6 -1.7 -0.0 0.6 0.7 0.7 -0.5 -0.4
Arm fat-free mass (left) 0.6 3.0 8.3 -0.4 2.5 0.9 0.7 1.3 2.5 0.8 -1.1 1.8 2.0 -1.1 2.9 2.3 1.5
Number of operations (self-reported) 0.4 0.6 1.8 0.4 -1.3 -0.4 1.1 0.7 0.6 0.4 0.6 0.1 -0.9 0.3 -1.3 -0.2 -1.2
Average weekly beer plus cider intake 1.3 1.9 5.5 2.4 0.3 0.6 1.4 2.1 1.4 1.0 1.9 1.4 0.9 -1.9 -0.4 0.6 1.2
Irritability 1.4 2.3 4.5 -2.0 -1.1 -1.2 -1.4 -1.8 -1.4 -2.1 -1.9 -2.1 -1.5 1.2 0.4 -1.1 -0.9
Risk taking 0.5 0.7 3.1 -1.1 0.4 -0.1 -0.8 0.1 0.2 -0.9 -1.1 0.2 0.7 0.7 1.7 1.1 -0.4
Ever had prostate specific antigen (PSA) test 0.6 0.7 2.1 0.0 0.7 0.9 1.0 1.0 1.0 1.4 0.8 0.4 0.6 -1.4 -0.7 -0.2 0.1
Fractured/broken bones in last 5 years 0.3 0.4 2.7 0.4 1.6 0.9 1.1 0.2 0.2 -0.2 -0.1 0.7 -0.1 -0.4 -0.1 0.6 0.1
Age started oral contraceptive pill 1.2 1.5 6.7 -0.9 -1.2 -1.3 -1.2 -1.4 -2.6 -0.2 -0.5 -0.6 -1.1 1.4 -1.1 -0.9 -0.8
Diastolic blood pressure, automated reading 1.6 4.9 10.9 3.3 1.5 2.4 2.3 2.3 2.1 1.4 3.0 2.5 2.3 -1.8 0.4 2.4 1.5
Ever depressed for a whole week 2.5 3.1 5.7 -1.8 -1.4 -2.2 -1.7 -1.0 -1.3 -1.6 -1.7 -1.9 -2.0 2.3 0.8 -2.4 -1.9
Unable to work because of sickness or disability 0.9 1.2 3.1 1.4 0.6 1.0 1.2 1.5 1.5 -0.5 0.7 1.5 0.6 -0.3 0.7 1.8 0.5
Commuting to job workplace: Cycle 0.7 0.8 3.1 -1.2 0.0 -0.6 -0.8 -1.3 -1.8 -0.0 -0.5 -0.6 -0.5 0.2 -1.3 -1.1 -0.6
Myopia 0.3 0.4 1.3 -0.1 -0.2 -0.6 -0.3 0.1 -0.9 1.1 0.9 -0.3 0.3 -0.5 -0.4 -1.2 -0.1
Vascular/heart problems diagnosed by doctor 3.6 9.8 18.4 -4.3 -2.5 -4.2 -2.5 -2.9 -2.4 -2.7 -3.8 -3.8 -3.4 3.2 -1.0 -3.1 -2.3
Cholesterol lowering medication 2.9 4.3 11.8 3.1 1.0 2.4 1.6 1.7 2.2 1.1 1.9 2.5 1.7 -1.4 1.2 3.4 2.2
Medication: Omeprazole (e.g. Zanprol) 1.4 1.8 7.0 1.2 1.1 1.5 0.9 0.8 1.0 0.9 1.9 1.5 2.6 -1.2 0.0 1.0 1.1
Pain experienced in last month 1.1 1.8 4.3 -1.4 -0.7 -1.2 -2.1 -1.9 -1.6 -1.3 -0.9 -1.4 -1.5 1.2 1.1 -0.7 -0.8
Supplements: Calcium 0.5 0.5 3.2 0.1 -1.8 -0.3 0.3 -0.1 -0.3 0.1 0.1 -0.7 -1.0 0.2 -1.4 -0.1 -0.2
Basal cell carcinoma (self-reported) 2.5 3.0 5.2 1.6 2.0 2.1 1.9 2.0 2.2 0.9 1.2 2.3 2.3 -1.4 0.0 1.8 0.5
Heart attack/myocardial infarction (self-reported) 2.6 3.3 6.0 1.9 1.3 2.0 2.4 2.5 2.1 1.6 1.7 1.8 1.9 -2.1 -0.9 1.5 0.9
Deep venous thrombosis (DVT) (self-reported) 1.5 2.0 5.0 -1.0 -1.2 -2.2 -1.8 -1.3 -1.4 -0.6 -1.2 -1.7 -1.6 1.0 0.3 -2.2 -0.6
Heart disease (siblings) 0.4 0.5 2.9 0.3 -1.3 0.1 -0.5 0.1 -0.5 -0.4 -0.3 0.0 0.1 0.1 1.7 0.7 0.7
Alcohol drinker status: Previous 0.3 0.3 1.1 -1.0 0.9 -0.1 -0.0 -0.3 0.2 0.6 -0.1 0.8 1.1 0.2 -0.6 -0.4 -0.0
Pack years of smoking 1.4 2.0 5.9 1.8 0.4 1.2 1.9 1.8 2.4 0.2 1.0 1.6 1.2 -0.9 0.2 2.0 0.9
Impedance of whole body 0.4 1.9 4.9 -0.5 -0.4 -0.7 -1.0 -1.2 -1.9 -0.7 0.7 -1.6 -1.9 0.8 -1.8 -2.2 -2.0
Leg fat mass (left) 0.3 1.1 4.1 -0.5 1.3 -0.2 0.5 0.6 2.0 -0.7 -2.0 0.2 0.8 0.6 1.7 0.0 -0.3
Arm predicted mass (left) 0.7 3.7 8.9 -0.1 2.9 1.2 0.9 1.4 2.7 1.1 -0.8 2.2 2.2 -1.4 3.0 2.5 1.8