Hub : Genes

KIAA1841

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0460	0.0160	3.0e-07	0.055	0.053	0.058	0.051	0.056	2.9e-07	4.2e-07	1.2e-07	6.6e-07	2.3e-07
2	GTEx	Adrenal Gland	0.1280	0.0570	4.7e-03	0.008	NA	0.024	NA	0.004	1.6e-01	NA	4.6e-02	NA	2.3e-01
3	GTEx	Brain Cerebellar Hemisphere	0.1610	0.0710	6.6e-04	0.076	NA	0.089	NA	-0.009	5.4e-03	NA	2.7e-03	NA	6.2e-01
4	GTEx	Brain Cerebellum	0.0990	0.0480	2.6e-03	0.048	NA	0.036	NA	0.053	1.6e-02	NA	3.2e-02	NA	1.2e-02
5	GTEx	Brain Cortex	0.1080	0.0560	4.6e-03	0.055	NA	0.054	NA	0.057	1.3e-02	NA	1.3e-02	NA	1.1e-02
6	GTEx	Brain Nucleus accumbens basal ganglia	0.1710	0.0730	6.1e-04	0.165	NA	0.141	NA	0.177	3.5e-05	NA	1.3e-04	NA	1.7e-05
7	GTEx	Brain Putamen basal ganglia	0.1620	0.0850	5.6e-03	0.162	NA	0.107	NA	0.127	1.2e-04	NA	1.7e-03	NA	6.3e-04
8	GTEx	Esophagus Muscularis	0.0650	0.0270	1.2e-04	0.104	NA	0.102	NA	0.102	7.2e-07	NA	9.0e-07	NA	9.7e-07
9	GTEx	Nerve Tibial	0.0615	0.0272	2.8e-04	0.010	NA	0.017	NA	0.019	6.1e-02	NA	2.2e-02	NA	1.5e-02
10	GTEx	Thyroid	0.0630	0.0290	1.4e-03	0.006	NA	0.020	NA	0.010	1.0e-01	NA	1.0e-02	NA	5.6e-02
11	ROSMAP	Brain Pre-frontal Cortex	0.1428	0.0397	1.0e-12	0.127	0.114	0.093	0.125	0.126	4.8e-16	1.7e-14	4.8e-12	8.2e-16	6.2e-16
12	TCGA	Breast Invasive Carcinoma	0.0597	0.0344	4.3e-03	0.001	0.012	0.025	NA	0.001	2.0e-01	1.1e-03	5.4e-06	NA	1.8e-01
13	TCGA	Lung Squamous Cell Carcinoma	0.0471	0.0257	4.2e-03	0.016	0.017	0.012	NA	0.013	5.2e-03	4.5e-03	1.4e-02	NA	1.0e-02
14	TCGA	Pheochromocytoma and Paraganglioma	0.1620	0.0780	3.1e-03	0.021	0.031	0.029	NA	0.007	4.8e-02	2.1e-02	2.4e-02	NA	1.6e-01

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14
Bipolar Disorder (2018)	0.7	1.1	4.4	-1.6	1.6	-0.1	-1.6	-1.3	0.2	0.1	-1.3	-0.3	0.6	0.1	2.1	-0.7	-0.1
Bipolar Disorder or Schizophrenia	0.5	1.2	6.4	-1.6	0.7	0.0	-1.5	-1.3	0.0	0.3	-1.5	-0.3	0.5	0.1	2.5	-0.8	0.4
Depressed Affect (Nagel 2018)	3.8	8.0	12.8	-2.7	-2.2	-3.6	-2.5	-2.1	-1.8	-3.3	-3.1	-3.1	-3.2	3.3	1.2	-3.5	-3.0
Depression (Nagel 2018)	2.5	3.7	8.4	-1.5	-1.7	-2.6	-1.0	-0.7	-0.5	-2.6	-2.2	-1.7	-1.8	2.9	0.4	-2.0	-2.8
Intelligence (Savage-Jansen 2018)	0.8	2.5	6.4	-2.4	-0.1	-1.2	-2.1	-2.5	-2.1	-0.8	-2.3	-1.5	-0.8	0.9	1.6	-0.1	0.2
Neuroticism (Nagel 2018)	6.0	14.2	21.8	-3.9	-3.0	-4.7	-3.6	-3.5	-3.0	-4.5	-4.3	-4.5	-4.2	4.0	1.2	-3.8	-2.9
Schizophrenia (2018)	0.2	0.4	2.3	-0.7	-0.4	0.1	-0.6	-0.6	-0.1	0.3	-0.9	-0.2	0.2	0.0	1.5	-0.4	0.5
Schizophrenia vs Biploar Disorder	0.1	0.2	1.9	-0.3	-1.4	0.1	-0.2	-0.2	0.1	-0.0	0.2	0.3	0.1	0.3	0.3	0.2	0.1
Worry (Nagel 2018)	5.9	12.4	19.5	-4.0	-2.4	-4.3	-3.7	-3.6	-3.4	-3.8	-4.4	-4.1	-3.4	3.7	1.0	-3.4	-2.7
Alzheimer’s Disease (in mother)	0.6	0.7	3.3	0.5	-0.8	0.5	0.9	0.4	-0.7	1.0	0.6	-0.2	-0.2	-1.0	-1.8	-1.2	0.2
Alzheimer’s Disease (in father)	3.0	3.3	10.4	-2.4	-1.3	-1.8	-2.1	-3.2	-2.1	-0.4	-1.4	-2.1	-1.6	1.1	-1.1	-2.1	-0.2
Alzheimer’s Disease (including proxy)	0.4	0.6	1.9	-0.6	-0.6	-0.0	-0.3	-1.2	-1.4	0.3	0.0	-0.6	-0.1	-0.3	-1.3	-1.4	-0.3
Crohns Disease (2017)	6.4	14.1	26.9	-4.2	-1.4	-4.1	-4.1	-3.9	-5.2	-4.0	-4.0	-4.5	-3.0	3.9	0.6	-3.8	-3.6
Irritable Bowel Disease (IBD)	14.2	33.8	61.3	-5.9	-4.1	-6.6	-6.1	-5.7	-7.6	-5.3	-5.8	-7.8	-6.4	5.3	-0.1	-6.4	-4.3
Ulcerative Colitis (UC)	14.5	27.2	57.2	-5.2	-5.1	-6.2	-5.0	-4.8	-6.4	-3.9	-5.0	-7.6	-6.8	4.1	-1.0	-5.8	-2.6
Major Depression (MDD)	0.2	0.3	1.6	0.3	-0.0	0.4	-0.2	-0.2	0.8	-0.2	-0.3	-0.4	-0.4	0.6	1.2	0.4	-0.0
Reaction Time	1.1	2.1	4.4	2.1	0.9	2.0	1.9	1.5	0.9	0.8	1.8	1.7	1.0	-1.2	-0.5	1.2	1.3
Verbal and Numeric Reasoning (VNR)	1.3	3.2	8.9	-3.0	0.2	-1.1	-2.2	-2.4	-1.9	-1.1	-2.8	-1.6	-1.0	1.6	1.9	0.2	-0.9
Breast Cancer	0.5	1.3	3.5	1.6	0.9	1.1	1.5	1.3	1.9	-0.1	1.2	0.9	0.9	-0.5	0.2	1.5	-0.3
Ovarian Cancer	0.4	0.5	1.8	0.2	0.1	1.1	0.5	0.4	0.3	1.2	0.5	0.5	0.8	-0.2	0.3	1.4	0.8
Prostate Cancer	0.3	0.5	1.4	-0.0	0.6	0.5	0.6	0.6	1.1	1.0	0.2	0.6	0.8	-1.2	-0.2	0.2	0.9
Age at First Birth	7.0	10.2	17.5	-3.9	-2.5	-3.2	-3.3	-4.2	-4.0	-2.5	-3.7	-3.8	-3.6	3.1	0.4	-2.3	-2.0
Bipolar Disorder (2011)	0.5	0.5	2.2	-0.2	1.5	-0.2	-0.4	-0.6	0.0	-1.0	-0.6	0.1	0.2	0.7	-0.7	-0.9	-1.1
Body Mass Index (BMI) (2010)	1.0	1.4	3.8	1.9	0.9	0.9	1.5	1.8	1.9	0.3	1.0	1.1	0.8	-0.7	-0.1	1.2	0.6
Coronary Artery Disease (CAD)	0.3	0.3	1.5	-0.5	0.1	-0.3	-0.3	0.4	0.2	-1.1	-0.9	-0.2	-0.3	1.2	-0.3	0.1	-0.2
Crohns Disease (2012)	2.7	4.3	10.8	-2.1	-0.5	-1.9	-1.9	-1.9	-3.3	-2.0	-1.5	-2.6	-1.6	2.1	-0.4	-2.5	-2.8
Mean Putamen Volume	1.3	1.5	7.3	0.6	-0.3	1.0	-0.8	-0.8	-0.2	1.1	-0.5	-0.1	0.7	-0.9	1.7	2.2	2.7
Fasting Glucose	0.7	0.9	3.7	0.4	-0.6	-0.6	-0.9	-0.6	-1.8	-0.7	0.1	-1.1	-1.9	0.6	0.9	-0.3	-0.3
HbA1C	0.5	0.6	3.5	-0.0	-0.6	0.8	-1.2	-1.0	-0.4	0.1	0.3	-0.2	-0.3	0.5	1.9	0.5	0.7
HDL Cholesterol	0.8	1.3	9.2	-0.4	-0.8	-1.3	-1.0	-0.7	-0.9	-0.7	-0.5	-1.3	-1.1	-0.3	-0.3	-3.0	0.4
LDL Cholesterol	0.2	0.3	0.8	0.9	-0.0	0.1	0.6	0.3	0.4	-0.7	0.8	0.1	0.4	0.7	-0.5	0.7	-0.5
Lupus	2.0	3.0	10.4	-1.1	-1.8	-1.7	-0.8	-1.3	-0.4	-2.0	-0.7	-1.9	-2.4	1.7	-0.8	-2.1	-3.2
Neuroticism (2016)	6.0	8.7	15.8	-3.6	-2.0	-3.2	-3.1	-3.3	-2.5	-2.8	-3.4	-3.2	-2.7	4.0	1.0	-2.7	-2.6
Primary Biliary Cirrhosis	0.5	0.7	2.3	-0.6	0.6	-0.8	-0.7	-0.6	1.1	-1.4	-1.0	0.2	-0.5	1.5	0.4	0.6	-1.2
Rheumatoid Arthritis	1.0	1.4	5.3	1.8	-1.5	0.2	1.2	1.6	0.7	0.2	1.5	0.0	-2.3	-0.2	-1.3	-0.0	-0.2
Schizophrenia (2014)	0.5	1.0	6.2	-1.4	0.3	0.2	-1.1	-1.5	0.0	0.1	-1.4	-0.4	0.2	0.0	2.5	-0.6	0.7
Triglycerides	1.1	1.8	5.2	2.0	0.8	1.1	2.3	2.2	1.4	-0.3	1.4	1.0	0.3	-0.3	-1.2	1.5	-0.6
Type 2 Diabetes (T2D) (2012)	0.5	0.6	1.7	-1.3	-0.1	-0.4	-0.6	-0.7	-1.2	0.8	-0.6	-0.6	-0.7	0.7	0.4	-1.0	-0.4
Ulcerative Colitis	8.7	12.6	28.4	-3.5	-2.9	-4.2	-3.2	-3.1	-4.3	-1.9	-3.0	-5.3	-4.5	2.6	-1.2	-4.9	-2.6
Blood Eosinophil Count	4.0	30.6	62.3	5.3	5.6	7.7	4.3	5.1	3.7	4.2	7.3	7.8	7.9	-4.6	0.3	5.5	2.0
Blood Platelet Count	0.8	9.3	28.3	3.9	2.2	3.0	3.0	3.3	2.9	2.4	5.3	3.8	2.6	-3.0	-2.6	1.2	0.5
Blood Red Count	0.5	4.7	20.1	-4.0	1.3	-1.3	-0.2	-0.5	1.0	-1.6	-2.5	0.2	0.6	3.1	-0.5	-2.5	-4.5
Blood White Count	11.1	82.3	123.2	9.9	5.5	11.1	8.9	9.2	8.6	9.0	10.7	10.9	10.7	-9.4	-1.8	9.0	7.7
Heel T-Score	0.1	0.9	3.5	0.8	-1.1	-0.6	-0.1	0.4	0.6	-1.2	1.2	0.0	-0.8	1.9	-0.8	-0.7	-1.6
BMI	0.5	2.7	11.0	0.8	1.3	1.1	1.6	1.6	3.3	0.3	-1.1	1.2	1.9	-0.9	1.5	1.9	2.3
Height	0.4	7.4	35.8	-0.6	6.0	2.8	0.5	1.1	2.5	2.2	1.4	3.5	3.1	-1.8	3.4	2.5	-1.3
Waist Hip Ratio (WHR)	0.8	3.7	8.7	2.2	1.2	1.8	1.8	1.2	1.0	2.2	2.7	1.4	2.1	-3.0	-2.8	-0.8	0.7
Systolic Blood Pressure	0.6	2.9	14.1	3.8	0.4	1.7	1.7	2.1	1.1	-0.3	2.0	1.2	0.8	-1.4	0.9	2.2	1.1
Smoking Status	1.8	4.3	10.8	3.3	0.6	2.0	3.1	3.0	2.7	1.2	2.1	2.1	1.3	-2.1	-0.4	1.2	1.1
Allergy or Eczema	6.2	16.5	27.8	-5.1	-0.2	-4.3	-5.2	-4.3	-5.3	-3.7	-4.3	-4.0	-2.7	4.4	2.0	-3.7	-4.4
Cardiovascular Disease	2.9	9.5	17.0	4.1	2.8	4.0	2.5	2.2	2.7	2.5	3.4	3.8	3.8	-3.1	0.5	3.1	2.7
Hypothyroidism (self reported)	2.5	5.6	11.7	-2.4	-1.0	-2.7	-2.8	-2.4	-2.3	-3.1	-2.5	-2.3	-2.0	3.4	1.5	-0.9	-2.4
Respiratory disease	1.0	2.3	10.8	-1.0	-2.4	-0.9	-2.2	-1.6	-3.3	-0.3	-0.6	-2.1	-0.4	0.3	0.6	-0.8	0.8
Type 2 Diabetes (T2D) (2018)	0.2	0.3	1.2	0.9	-0.6	0.4	0.5	0.4	0.2	-1.1	0.3	0.4	0.2	0.0	-0.4	0.5	-0.9
Lung FEV1/FVC ratio	5.1	25.7	47.9	-6.9	-3.6	-6.9	-4.7	-4.3	-3.6	-5.2	-6.6	-5.7	-4.6	5.3	-0.5	-5.4	-3.9
Lung FVC	2.3	11.9	22.5	3.6	1.6	3.8	4.2	3.0	3.6	4.5	4.7	3.4	4.1	-2.7	-4.2	1.5	0.6
Neuroticism	5.5	13.2	20.7	-3.5	-3.1	-4.2	-3.3	-3.2	-3.5	-4.5	-4.1	-4.1	-4.1	4.3	0.9	-3.4	-3.2
Chronotype (morning person)	4.1	9.6	21.2	-4.6	-1.6	-3.7	-3.0	-3.1	-2.7	-3.4	-3.4	-2.5	-2.1	4.1	0.2	-2.0	-4.0
Hair Pigment	0.1	1.8	9.4	-0.4	3.1	0.8	-0.1	-0.5	0.8	0.4	-0.8	0.5	1.4	0.1	2.6	2.1	0.8
Tanning	0.2	2.1	5.9	-1.8	-0.9	-1.8	-1.5	-2.0	-1.1	0.5	-1.4	-1.9	-1.4	0.4	-0.7	-2.4	-0.2
Hand grip strength (left)	0.4	1.1	3.2	0.7	0.5	1.5	0.1	-0.0	-0.7	1.0	0.1	-0.0	0.7	-1.5	1.6	1.8	1.6
Number of treatments/medications taken	0.3	0.5	2.5	1.6	0.6	0.9	0.3	0.7	0.1	-0.5	0.9	0.8	0.8	-0.1	0.5	0.5	-0.7
Average weekly spirits intake	0.5	0.7	2.2	-0.1	-0.6	-1.1	-0.0	0.1	-0.5	-1.5	-0.9	-0.7	-1.1	1.0	0.1	-0.6	-1.0
Sensitivity / hurt feelings	0.4	0.7	2.0	-0.1	-0.9	-0.3	-0.7	-0.6	-1.1	-0.2	-0.7	-1.2	-0.9	-0.5	1.0	-0.3	1.4
Frequency of depressed mood in last 2 weeks	3.7	5.1	9.3	-2.1	-2.0	-3.0	-1.9	-1.6	-1.3	-2.5	-2.7	-2.7	-2.7	2.7	1.0	-2.2	-2.2
Hearing difficulty/problems: Yes	0.6	0.9	2.0	-1.1	-1.4	-0.6	-1.1	-1.2	-1.2	-0.5	-1.2	-1.1	-1.0	1.1	0.5	0.1	-0.2
Relative age of first facial hair	4.1	8.5	19.3	-3.6	0.1	-3.4	-2.5	-3.0	-2.2	-2.9	-3.1	-2.6	-2.4	4.1	0.6	-2.8	-4.4
Other serious medical condition/disability diagnosed by doctor	4.0	5.2	10.6	-2.2	-1.1	-2.6	-2.4	-1.6	-3.0	-3.2	-2.6	-2.2	-1.9	2.5	1.3	-1.9	-2.2
Ever used hormone-replacement therapy (HRT)	0.6	0.8	1.9	0.1	-0.5	-0.8	-1.0	-0.6	-0.4	-1.4	-0.8	-0.2	-0.8	1.0	1.4	0.9	1.1
Ever had hysterectomy (womb removed)	1.7	1.9	4.1	-1.1	-1.6	-1.8	-1.2	-1.0	-1.3	-2.0	-1.8	-1.3	-1.4	2.0	0.5	-0.2	-1.2
Systolic blood pressure, automated reading	0.3	0.8	3.2	1.8	-0.6	-0.2	0.2	0.5	-0.0	-1.5	0.2	0.2	-0.6	0.6	1.4	1.5	0.6
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.3	1.0	0.1	0.2	0.9	1.1	0.2	-0.1	0.0	0.4	-0.6	-0.3	-0.7	-0.1	0.1
Angina	0.6	0.8	2.4	0.1	-1.6	-0.3	-0.2	0.9	1.1	-1.2	-0.8	-0.4	-1.0	1.0	1.3	0.8	-0.6
Medication for hormone replacement therapy	1.7	1.9	5.9	-1.5	-0.7	-1.9	-1.0	-0.6	0.3	-1.6	-2.4	-1.8	-1.5	1.2	1.9	-0.2	0.7
Vitamin and mineral supplements	0.7	0.9	2.7	-1.6	0.6	-1.1	-0.9	-0.8	-0.5	-0.3	-1.5	-0.5	-0.6	0.7	0.3	-1.5	-0.8
Supplements: Zinc	0.8	0.9	4.8	-0.3	-2.2	-0.6	-0.9	-1.2	-0.8	-0.7	-0.2	-1.4	-1.2	0.7	-0.4	-0.1	-0.0
Medication: Co-codamol	0.7	0.8	2.5	1.6	0.5	0.9	1.3	1.2	0.3	0.1	1.3	0.9	-0.6	-0.4	-0.1	1.1	0.2
Medication: Metformin	0.2	0.2	0.8	0.9	-0.9	0.3	0.2	0.6	-0.1	-0.4	-0.1	-0.3	-0.2	-0.6	0.4	0.6	0.0
Diabetes (father)	0.9	1.1	3.6	-0.9	-1.3	-1.0	-0.2	-0.3	-1.0	-0.5	-1.4	-1.9	-1.6	0.4	-0.3	-1.3	-0.6
Diabetes (mother)	0.4	0.5	1.9	-0.9	0.8	-0.6	-0.7	-0.7	-0.6	-1.4	-1.3	-0.2	0.2	0.5	0.6	0.0	-0.6
Severe depression (siblings)	0.6	0.6	1.6	0.9	-1.3	-0.2	0.4	1.1	-0.5	0.6	0.7	-0.2	-1.1	-0.6	-1.2	-0.8	0.6
Pack years adult smoking proportion	1.8	2.7	7.6	2.0	0.8	1.5	2.0	2.1	2.8	0.3	1.3	1.9	1.6	-1.2	0.6	2.2	0.8
Impedance of leg (right)	0.2	1.2	3.5	-0.1	-1.0	-0.6	-0.7	-1.2	-1.9	-0.4	0.4	-1.4	-1.3	0.1	-1.7	-1.6	-0.7
Leg fat-free mass (left)	0.5	2.9	9.1	-0.7	2.8	1.1	0.4	1.2	2.3	0.7	-1.1	1.6	2.1	-0.9	3.0	2.0	1.3
Trunk fat percentage	0.2	0.8	4.0	0.1	2.0	0.3	0.7	0.8	1.9	-0.4	-0.8	0.5	0.8	0.5	0.8	0.1	-0.6
Hand grip strength (right)	1.2	3.2	6.9	1.8	1.5	2.6	1.2	1.0	0.9	2.5	1.7	1.4	1.6	-2.3	1.2	2.4	1.8
Townsend deprivation index at recruitment	0.2	0.3	0.9	0.6	-0.3	-0.3	-0.1	0.9	-0.3	-1.0	0.5	-0.0	-0.6	0.5	0.6	-0.2	-0.5
Current tobacco smoking	0.8	1.3	5.9	2.4	0.8	0.9	1.7	1.4	1.4	-0.1	1.3	1.3	0.4	-0.6	-0.2	0.2	-0.1
Average weekly fortified wine intake	0.4	0.5	3.5	-0.3	-0.4	-0.7	0.5	-0.5	-0.3	0.2	-0.1	-0.4	-0.7	-0.1	-1.9	-0.7	0.7
Maternal smoking around birth	2.4	3.4	9.6	1.3	1.6	2.0	1.9	2.5	3.1	1.1	1.7	2.5	1.7	-1.0	0.4	2.5	0.2
Fed-up feelings	2.4	4.4	9.1	-2.5	-1.1	-2.0	-3.0	-2.3	-1.3	-2.0	-2.5	-1.9	-1.2	2.0	2.8	-2.1	-1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	2.0	2.7	5.2	-1.7	-1.1	-1.9	-1.3	-1.3	-0.7	-1.5	-2.3	-1.5	-2.2	2.0	0.5	-1.9	-1.8
Relative age voice broke	0.4	0.6	4.0	0.0	0.4	-0.4	0.8	-0.0	-0.4	-0.7	-0.2	0.0	-0.0	1.1	-1.2	-0.3	-2.0
Taking other prescription medications	0.5	0.8	3.3	0.1	1.0	-0.1	-0.8	-0.3	-0.5	-1.6	0.0	0.2	0.7	1.2	1.1	0.5	-1.8
Age when periods started (menarche)	2.1	5.1	21.3	3.5	0.1	0.2	3.0	2.2	1.9	0.6	3.7	1.3	-0.7	-0.3	-4.6	-0.3	-1.7
Bilateral oophorectomy (both ovaries removed)	0.8	1.0	2.8	-0.8	-1.7	-1.1	-0.8	-1.2	-1.4	-0.2	-0.8	-1.1	-0.5	0.7	-0.4	-1.5	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	3.6	1.9	-0.2	1.2	1.2	0.7	0.7	1.3	1.7	0.8	0.8	-0.7	-1.2	-0.0	0.3
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	2.7	1.0	0.3	0.7	1.1	1.3	1.4	0.9	0.9	0.8	1.1	-1.2	-0.3	1.6	1.1
Qualifications: CSEs or equivalent	0.7	0.9	3.0	0.5	1.5	0.5	0.6	1.7	1.6	-0.3	0.2	0.9	0.4	-0.5	1.3	-0.4	-0.7
Serious illness, injury or assault to yourself	1.3	1.6	4.4	-1.1	-1.0	-1.4	-1.3	-1.0	-0.5	-1.2	-1.1	-0.9	-2.1	1.7	1.6	-0.2	-1.3
High blood pressure	3.2	9.0	16.7	4.1	2.7	4.0	2.1	2.3	2.0	2.6	3.5	3.6	3.4	-3.2	1.0	3.2	2.6
Hayfever, allergic rhinitis or eczema	7.3	15.9	29.5	-5.0	-0.6	-4.2	-5.2	-4.1	-5.4	-3.8	-4.4	-4.0	-2.7	4.1	2.7	-3.3	-3.8
Multivitamins +/- minerals	0.7	0.8	2.9	1.7	0.0	1.4	0.8	0.5	0.6	0.3	1.7	0.4	0.6	-0.6	-0.2	1.2	0.7
Stomach or abdominal pain in last month	0.8	1.1	3.0	-0.3	0.1	-1.7	-0.3	0.4	0.1	-1.4	-1.1	-0.9	-1.6	1.2	0.4	-1.3	-1.4
Supplements: Glucosamine	6.5	8.5	15.1	3.1	1.3	3.6	2.9	3.0	3.9	2.6	2.9	3.6	3.3	-2.5	0.2	3.6	2.0
Diverticular disease/diverticulitis (self-reported)	2.9	3.5	7.5	2.6	1.7	1.7	2.7	2.7	2.3	1.5	2.0	1.6	1.6	-1.9	-1.0	-0.5	-0.1
Medication: Atenolol	2.4	3.0	7.4	2.3	1.7	2.2	1.8	2.0	2.7	0.2	0.7	1.8	0.9	-1.4	1.4	1.9	1.5
Medication: Levothyroxine sodium	2.4	4.0	7.2	-1.6	-0.8	-2.1	-2.6	-2.5	-2.7	-2.5	-1.8	-2.3	-2.0	2.4	0.6	-1.1	-1.5
Sitting height	0.4	2.7	9.9	-2.1	2.9	1.4	-1.1	-0.5	0.7	1.3	-0.8	1.2	1.8	-0.9	3.1	1.7	0.6
Chronic bronchitis/emphysema (father)	2.4	2.8	6.0	1.9	0.8	1.8	2.3	2.4	2.5	0.3	1.4	1.8	0.9	-1.4	0.0	2.2	1.2
High blood pressure (mother)	0.2	0.3	1.8	-0.2	-0.4	0.4	-0.1	-0.4	0.1	-0.2	-0.0	-0.2	1.4	0.1	0.2	1.4	-0.2
Body mass index (BMI)	0.3	1.3	5.2	0.1	1.0	0.3	0.9	1.1	2.3	-0.3	-1.4	0.8	1.4	0.1	1.6	1.0	1.0
Impedance of leg (left)	0.3	1.3	3.5	-0.1	-0.8	-0.9	-0.6	-1.1	-1.2	-0.5	0.3	-1.3	-1.7	0.6	-1.5	-1.9	-1.6
Leg predicted mass (left)	0.6	3.0	9.3	-0.7	2.8	1.1	0.5	1.3	2.4	0.7	-1.1	1.6	2.2	-1.0	3.0	2.0	1.3
Trunk fat mass	0.3	1.3	5.8	-0.2	2.4	0.4	0.6	0.8	2.2	-0.2	-1.1	0.7	1.2	0.2	1.5	0.4	-0.2
Waist circumference	0.8	2.9	8.4	1.2	2.3	1.4	1.8	2.0	2.9	0.9	0.3	2.0	2.5	-1.4	0.4	1.1	1.0
Number of incorrect matches in round	0.9	1.6	4.9	1.1	0.5	1.8	0.6	0.9	0.7	0.8	1.4	1.2	1.7	-1.0	0.2	2.2	1.6
Past tobacco smoking	0.9	1.7	4.9	-1.5	0.3	-1.2	-2.2	-2.0	-1.7	-0.9	-0.6	-0.7	-0.9	1.3	0.9	-0.7	-1.3
Alcohol usually taken with meals	0.8	1.3	2.9	-1.3	-1.7	-0.9	-1.5	-1.0	-1.2	-0.8	-0.9	-1.3	-1.5	1.3	0.9	0.1	-0.5
Nervous feelings	4.0	7.5	13.0	-2.8	-1.4	-2.7	-3.3	-3.1	-2.8	-2.8	-3.1	-3.6	-2.9	2.5	1.7	-2.8	-2.1
Frequency of tenseness / restlessness in last 2 weeks	2.2	3.4	7.0	-1.9	-1.0	-2.5	-1.4	-1.5	-0.2	-1.9	-2.2	-1.9	-2.1	2.6	0.6	-2.1	-2.2
Hearing difficulty/problems with background noise	2.3	3.7	9.2	-2.5	-1.2	-1.6	-2.6	-3.0	-2.0	-1.0	-2.4	-2.0	-1.5	2.1	1.4	-1.5	-1.1
Hair/balding pattern: Pattern 2	3.9	5.0	10.2	2.5	1.8	2.5	2.6	2.5	2.0	2.4	3.2	3.0	2.3	-1.9	-1.0	1.7	0.4
Had menopause	0.4	0.5	1.6	0.3	-0.5	-0.9	-0.3	-0.6	-0.7	-1.3	-0.6	-0.6	-1.1	0.7	-0.2	-0.1	-0.7
Had other major operations	0.8	1.0	3.3	-0.3	-0.7	-1.1	-0.3	-0.3	0.4	-1.8	-0.9	-0.3	-1.2	1.6	0.6	0.8	-1.7
Forced vital capacity (FVC)	1.6	6.2	11.9	1.9	2.8	3.1	2.5	2.1	2.8	3.5	3.0	2.9	2.8	-2.4	-1.2	1.7	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	2.3	1.2	-1.5	0.1	0.4	-0.0	-0.2	0.6	0.7	-0.7	-0.6	-0.1	-1.2	-0.6	0.3
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	2.3	-0.9	-0.9	-1.1	-0.7	-0.3	-1.0	-1.0	-0.5	-0.6	-1.2	1.2	0.0	-1.3	-1.5
Qualifications: None of the above	0.8	1.6	6.1	2.5	0.1	0.4	1.7	1.2	1.2	0.0	1.8	0.7	0.4	-0.8	-2.4	0.1	0.7
Financial difficulties in last 2 years	0.5	0.6	2.8	0.0	-1.7	-0.8	-0.1	0.3	-0.4	-0.5	-0.8	-1.0	-1.3	0.4	0.3	-0.8	0.5
Mouth/teeth dental problems	1.4	2.2	5.3	0.3	2.1	1.9	0.3	0.4	0.9	0.7	0.3	1.7	2.1	-1.4	1.7	2.3	1.8
Heart attack	2.9	3.8	6.8	2.2	1.2	2.2	2.6	2.6	2.2	1.8	2.0	1.9	1.9	-2.2	-1.0	1.5	0.8
Allergy	7.0	16.2	37.5	4.6	1.9	4.2	5.4	4.1	6.1	3.3	3.8	4.6	2.4	-3.9	-2.6	3.6	3.5
Pain all over the body in last month	0.3	0.3	1.0	0.5	-0.1	-0.1	0.9	0.8	0.5	0.2	0.5	0.7	0.2	0.0	-0.9	-0.5	-1.0
Diabetes (self-reported)	0.4	0.6	4.1	0.4	-2.0	-0.2	0.1	0.5	-0.6	-1.2	-0.7	-0.5	-0.7	0.3	0.1	0.5	-0.1
Hayfever/allergic rhinitis (self-reported)	1.0	1.4	3.4	-1.2	1.0	-0.7	-1.4	-1.2	-1.9	-1.3	-1.4	-0.5	-0.3	1.1	1.8	0.0	-1.0
Medication: Ramipril	1.0	1.3	2.8	1.3	1.7	1.5	-0.1	0.7	0.5	-0.5	0.7	1.5	1.5	-0.1	1.6	1.4	-0.1
Medication: Simvastatin	1.3	1.9	7.0	2.6	-0.3	1.3	1.3	1.7	1.3	0.4	1.7	1.4	0.6	-0.9	-0.7	1.8	1.1
Fluid intelligence score	3.8	8.0	14.2	-3.8	-0.9	-2.8	-3.4	-3.4	-3.5	-2.5	-3.5	-3.3	-2.9	2.6	1.2	-1.6	-2.3
Illnesses of siblings	2.6	3.6	8.5	-2.6	-0.6	-2.4	-1.7	-1.9	-1.5	-1.2	-1.5	-2.1	-1.7	1.9	-0.9	-2.9	-2.2
Neuroticism score	5.6	11.7	18.8	-3.8	-2.1	-3.9	-3.7	-3.5	-2.7	-3.7	-4.3	-4.3	-3.5	3.3	2.0	-3.6	-2.3
Weight	0.5	2.2	6.7	-0.7	2.6	0.6	0.5	0.9	2.5	0.3	-1.5	1.2	1.8	-0.4	2.5	1.4	0.9
Impedance of arm (right)	0.2	0.9	3.3	0.1	0.2	0.6	-0.1	-0.0	-1.4	-0.2	1.6	-0.5	-0.5	0.1	-1.6	-1.0	-1.8
Arm fat percentage (right)	0.2	0.8	2.9	0.1	1.2	0.7	0.9	0.9	1.7	-0.4	-1.0	0.4	1.4	0.4	0.9	0.4	-0.0
Trunk fat-free mass	0.5	3.1	8.5	-0.6	2.7	1.0	0.4	1.0	2.2	1.2	-0.8	1.9	2.2	-1.3	2.9	2.2	1.8
Hip circumference	0.2	1.1	4.2	-0.3	1.7	0.4	0.2	0.9	1.8	0.1	-1.1	0.8	0.8	-0.0	2.0	0.8	0.5
Time employed in main current job	0.6	0.7	3.5	-0.6	0.8	0.2	-0.5	-1.4	-0.4	0.1	-0.4	-0.1	0.6	-0.1	0.8	1.3	1.9
Alcohol intake versus 10 years previously	0.7	1.1	3.3	0.2	1.8	0.5	0.9	1.3	1.8	0.1	1.0	1.6	0.9	-0.1	0.3	-0.3	-1.2
Father’s age at death	1.7	2.3	5.3	-2.3	-0.3	-2.3	-1.0	-1.2	-1.2	-0.7	-1.4	-1.1	-1.1	1.7	-1.5	-2.0	-2.1
Worrier / anxious feelings	5.7	10.8	17.4	-3.8	-2.8	-3.7	-4.2	-3.8	-3.6	-3.3	-3.4	-3.7	-3.1	2.9	0.4	-3.5	-1.9
Frequency of tiredness / lethargy in last 2 weeks	2.3	3.8	6.9	-1.4	-2.1	-2.4	-1.7	-1.4	-1.8	-2.2	-1.9	-2.4	-2.6	2.3	0.5	-2.0	-1.5
Falls in the last year	0.4	0.6	1.7	0.9	0.9	0.3	0.8	0.8	1.2	-0.8	0.6	1.3	0.6	0.1	0.0	0.2	-0.9
Hair/balding pattern: Pattern 3	2.5	3.8	7.2	-1.1	-1.3	-2.1	-1.9	-2.0	-1.4	-2.4	-1.5	-2.2	-1.9	2.6	0.2	-2.2	-2.7
Number of live births	0.7	1.0	2.7	1.2	-0.4	1.5	0.9	0.4	1.5	0.7	1.4	0.9	0.1	-0.1	0.3	1.6	0.9
Forced expiratory volume in 1-second (FEV1)	0.3	1.0	3.2	-0.8	1.4	0.6	0.6	0.1	1.2	1.8	0.5	0.7	1.1	-0.4	-1.2	-0.4	-1.3
Pulse rate	0.2	0.3	0.8	-0.3	-0.3	0.1	-0.9	-0.8	-0.6	-0.3	0.1	-0.5	0.6	0.0	0.7	0.7	0.6
Happiness	2.5	3.1	11.5	-1.3	-0.7	-1.8	-1.0	-0.8	-0.8	-1.4	-1.1	-1.5	-2.0	2.1	0.5	-3.1	-3.4
Noisy workplace	1.3	1.6	4.6	1.7	-0.5	1.8	1.4	1.2	0.1	0.8	2.1	1.6	1.5	-0.4	-1.0	0.5	-1.0
Qualifications: A levels/AS levels or equivalent	2.5	5.6	10.4	-3.0	-2.5	-1.9	-2.5	-2.5	-2.0	-2.6	-3.2	-2.4	-2.5	3.2	1.2	0.4	-1.2
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	8.7	-0.0	-1.4	0.6	0.5	0.2	0.2	1.5	-0.3	-0.0	1.0	-0.7	0.3	2.2	3.0
Mouth/teeth dental problems: Dentures	1.0	1.6	5.0	1.8	-0.3	-0.3	1.4	1.5	0.6	-0.8	1.8	0.7	-0.8	0.3	-2.2	-0.9	-2.0
Asthma	1.0	2.0	7.5	-1.4	-1.5	-0.8	-2.2	-1.2	-2.7	-0.7	-0.5	-1.6	0.1	1.2	1.0	-1.3	-1.3
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	2.6	-0.7	1.3	0.1	-0.4	0.0	0.8	-0.3	-0.6	0.3	0.4	0.3	1.6	-0.6	-1.4
Medication: Cholesterol lowering	1.3	2.0	5.2	2.3	0.4	1.0	1.6	2.2	1.6	0.7	2.0	1.4	0.9	-1.4	-1.3	0.4	-0.2
Depression (self-reported)	2.1	2.5	7.8	-1.7	-1.4	-0.8	-1.9	-1.9	-2.8	-0.9	-2.1	-2.0	-1.8	0.5	1.2	-1.0	0.0
Medication: Lansoprazole	1.7	2.0	7.6	1.5	-0.4	0.1	2.1	2.8	1.7	1.2	1.0	0.9	0.9	-1.6	-1.8	-0.3	0.1
Prospective memory result	2.0	2.4	6.8	1.4	2.6	1.1	2.0	2.0	1.6	1.1	1.7	2.3	1.3	-0.8	-1.0	0.4	-0.7
Lung cancer (father)	0.4	0.4	2.1	0.5	0.1	0.3	0.1	0.3	1.1	-0.3	-0.2	0.1	-1.1	0.3	0.8	1.4	0.2
Illnesses of mother	0.6	0.7	1.9	0.6	1.1	0.3	-0.1	0.3	1.0	1.3	1.0	0.7	-0.3	-1.2	0.1	-0.8	1.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.8	3.0	-0.8	1.7	0.3	0.5	0.0	1.4	1.3	0.3	0.6	0.7	-0.3	-0.9	0.0	-0.9
Pulse wave Arterial Stiffness index	1.9	2.2	5.0	-1.6	-0.9	-1.8	-1.4	-1.3	-0.6	-1.5	-2.0	-1.4	-2.2	2.1	0.9	-0.9	-1.0
Impedance of arm (left)	0.3	1.2	3.3	-0.2	-0.1	-0.2	-0.8	-0.7	-1.8	-0.4	1.2	-1.2	-1.2	0.4	-1.7	-1.7	-1.5
Arm fat mass (right)	0.4	1.5	5.4	-0.0	1.9	0.7	0.9	1.0	2.3	0.0	-1.1	1.0	1.7	0.0	1.8	1.0	0.5
Trunk predicted mass	0.5	3.0	8.7	-0.7	2.5	0.9	0.3	1.0	2.1	1.1	-0.9	1.8	2.1	-1.3	3.0	2.1	1.9
Standing height	0.2	2.0	13.6	-1.9	3.7	0.6	-0.8	-0.3	0.6	1.3	-0.4	0.8	1.0	-1.2	2.0	0.7	-0.1
Length of working week for main job	0.4	0.4	0.9	0.2	-0.5	0.3	0.9	0.9	0.4	0.4	0.8	0.6	0.8	-0.4	-0.9	0.8	0.1
Exposure to tobacco smoke at home	1.1	1.2	2.8	1.7	0.4	0.9	1.4	1.6	0.8	1.2	1.6	1.3	0.5	-1.3	0.2	0.4	0.1
Breastfed as a baby	0.4	0.5	2.1	-0.3	-0.6	0.0	-0.7	-1.1	-0.6	0.9	-0.4	-0.7	-0.1	-0.6	0.2	-0.3	1.5
Tense / ‘highly strung’	2.3	3.9	7.0	-2.4	-1.8	-2.3	-2.6	-2.4	-1.5	-1.6	-2.6	-2.5	-1.6	1.9	1.0	-1.4	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	5.1	7.7	11.4	-3.1	-1.6	-3.3	-2.7	-2.3	-2.3	-3.1	-3.0	-3.1	-3.2	2.9	0.7	-3.4	-2.9
Hair/balding pattern: Pattern 4	3.7	9.0	17.9	3.0	2.2	3.6	3.3	3.7	3.6	1.6	2.6	3.8	3.7	-2.1	-0.3	4.2	1.8
Birth weight of first child	0.6	1.1	2.9	-1.0	1.7	-0.5	-0.9	-0.7	1.5	-0.2	-0.2	0.5	-0.0	1.2	1.6	0.6	-1.6
Peak expiratory flow (PEF)	0.6	1.3	5.7	-2.4	-1.0	-1.0	-1.3	-1.0	-0.3	0.7	-1.4	-1.5	-0.6	-0.1	0.4	-1.4	-0.7
Pulse wave reflection index	1.1	1.3	5.9	-0.8	-1.4	-1.1	-0.4	-0.7	-0.9	-0.8	-1.4	-0.9	-2.4	1.3	-0.1	-1.0	-1.0
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.3	-0.7	-1.1	-0.8	-0.5	-0.9	-1.1	-0.3	-0.8	-1.1	-0.8	0.2	-0.6	-1.2	-0.1
Loud music exposure frequency	1.6	1.8	4.7	-1.9	-1.2	-1.6	-1.4	-1.3	-1.6	-0.6	-1.5	-1.5	-1.0	0.6	-0.1	-2.2	-0.5
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	1.9	-1.4	-0.3	-0.9	-0.5	-0.3	0.2	-0.0	-1.1	-0.4	-0.6	0.7	0.6	0.0	-1.1
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.3	-0.6	-0.7	-0.3	-0.7	-0.9	-0.3	1.1	-0.2	-0.5	-0.8	-0.3	-0.1	-1.2	0.5
Blood clot in the leg (DVT)	0.8	1.1	3.7	-0.3	-0.9	-1.6	-1.3	-0.8	-1.1	-0.3	-0.5	-1.2	-1.4	0.5	0.2	-1.9	-0.3
Medication: Paracetamol	0.5	0.8	1.5	1.0	1.1	1.1	1.0	0.5	0.9	0.3	0.8	0.9	1.2	-1.2	-0.9	0.6	0.9
Headache pain in last month	0.2	0.3	1.0	-0.7	0.6	0.3	0.3	0.4	0.5	0.0	-0.6	-0.3	1.0	0.3	-0.1	-0.8	-0.3
Medication for cholesterol, blood pressure or diabetes	3.6	6.0	12.0	-3.5	-1.5	-2.9	-2.3	-2.9	-2.6	-2.0	-2.8	-2.9	-2.3	2.9	0.0	-2.2	-1.7
Glaucoma (self-reported)	1.5	1.7	5.5	2.3	0.7	1.3	1.2	1.2	1.0	0.4	2.1	1.9	1.0	-0.6	-0.9	1.4	0.6
Gout (self-reported)	5.7	7.8	16.1	4.0	1.7	3.1	2.9	3.5	4.0	1.5	3.5	3.5	2.4	-2.4	-0.4	2.3	0.5
Hypothyroidism/myxoedema (self-reported)	1.6	3.2	6.9	-1.7	-0.4	-2.1	-2.4	-2.1	-2.1	-2.3	-1.7	-1.8	-1.2	2.6	0.8	-0.5	-1.5
Medication: Amlodipine	6.4	9.0	15.7	3.0	1.2	4.0	2.7	3.0	2.9	3.5	3.1	3.0	3.6	-3.6	-0.0	2.9	3.3
Medication: Ventolin 100micrograms inhaler	1.2	1.6	3.7	-1.2	-1.0	-0.9	-1.9	-1.4	-1.7	-0.8	-0.8	-1.6	-1.3	1.2	1.5	-1.0	-0.7
Birth weight	0.3	0.7	4.8	-0.2	1.6	-0.0	0.1	0.5	0.9	-0.2	0.2	0.6	-0.1	0.4	0.5	-0.4	-2.2
Chronic bronchitis/emphysema (mother)	0.6	0.7	1.7	-0.8	0.2	-0.4	-0.8	-0.7	-0.9	-1.2	-1.3	-0.8	-0.4	0.8	1.3	0.8	0.4
High blood pressure (siblings)	3.9	5.6	8.9	2.8	1.0	3.0	2.3	2.5	2.5	2.3	2.0	2.7	2.3	-2.4	0.5	3.0	2.5
Forced vital capacity (FVC), Best measure	1.7	6.3	11.7	1.8	3.1	3.0	2.5	2.1	3.0	3.4	2.9	2.9	2.7	-2.5	-1.0	2.0	0.7
Body fat percentage	0.2	0.7	2.5	-0.2	1.4	-0.1	0.6	0.5	1.6	-0.7	-1.3	0.1	0.6	0.8	0.7	-0.3	-0.5
Leg fat percentage (right)	0.1	0.5	2.4	-0.2	0.6	-0.2	0.6	0.2	1.3	-0.5	-1.6	-0.1	0.8	0.5	0.5	-0.4	0.2
Arm fat-free mass (right)	0.4	2.0	7.8	-0.7	2.1	0.2	0.1	0.7	2.1	0.4	-1.5	1.2	1.2	-0.6	2.8	1.6	1.4
Exposure to tobacco smoke outside home	0.6	0.8	1.6	0.8	0.7	1.2	1.2	1.3	0.6	0.2	1.0	1.2	1.3	-0.5	0.6	-0.2	-1.1
Comparative body size at age 10	4.0	11.0	27.8	1.9	1.7	4.0	2.1	2.9	3.3	2.4	2.5	4.2	4.9	-3.1	1.7	5.3	3.9
Number of full brothers	0.5	0.6	2.4	1.1	0.7	-0.4	0.8	1.6	1.3	-0.4	0.0	0.5	-0.5	-0.4	0.7	0.4	0.5
Worry too long after embarrassment	4.2	7.1	12.5	-2.7	-0.5	-3.1	-2.8	-2.7	-2.2	-3.1	-2.8	-3.5	-2.5	2.9	0.9	-3.1	-2.7
Seen a psychiatrist for nerves, anxiety, tension or depression	3.9	5.0	11.5	-2.7	-1.3	-2.8	-1.7	-1.4	-1.3	-2.4	-2.4	-2.1	-2.3	2.6	0.6	-2.8	-3.4
Wheeze or whistling in the chest in last year	0.1	0.1	0.3	-0.1	-0.5	-0.4	0.1	0.3	0.2	0.1	-0.5	0.0	0.5	0.2	0.4	-0.3	0.2
Number of children fathered	1.1	1.2	4.5	-1.4	-1.0	-1.5	-0.7	-0.7	0.2	0.4	-1.2	-1.3	-1.5	0.3	-0.5	-2.1	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.8	1.0	5.0	0.5	0.7	0.3	0.5	0.8	1.1	-0.2	-0.7	0.3	0.9	-0.3	1.8	2.2	1.0
Age at first live birth	2.6	4.7	8.7	-2.9	-2.1	-2.4	-1.6	-2.0	-2.4	-1.8	-2.8	-2.4	-2.5	2.4	0.4	-0.9	-2.2
Pulse wave peak to peak time	1.7	2.0	4.4	1.4	1.1	1.6	1.3	1.3	0.7	1.4	1.9	1.3	2.1	-2.1	-0.7	0.9	0.9
Health satisfaction	1.2	1.6	4.5	-0.3	0.5	-0.9	-0.5	0.2	0.4	-2.1	-1.3	-0.6	-1.1	2.1	2.1	-0.0	-2.0
Shortness of breath walking on level ground	0.8	0.9	4.4	1.4	-0.6	0.9	1.0	1.0	0.7	0.0	0.6	0.6	0.8	-0.1	0.8	2.1	0.7
Qualifications: College or University degree	1.6	5.1	11.5	-3.4	-1.9	-1.5	-2.9	-3.0	-3.1	-1.7	-2.8	-2.4	-1.5	2.5	0.7	-0.0	-1.2
Eye problems/disorders: None of the above	0.5	0.5	3.3	-0.4	0.2	0.5	0.4	-0.1	0.8	1.8	0.4	0.2	1.0	-1.2	-0.4	-0.6	0.3
Mouth/teeth dental problems: Loose teeth	0.8	1.0	3.0	1.0	1.4	0.7	1.2	1.1	1.7	-0.9	0.5	1.1	0.7	-0.0	-0.4	0.9	-0.7
Emphysema/chronic bronchitis	2.3	2.6	7.2	-1.1	-2.7	-1.6	-1.8	-1.6	-1.6	-1.5	-1.6	-2.0	-1.8	1.6	1.3	0.4	0.6
Medication for pain relief, constipation, heartburn	1.0	1.7	2.9	-1.6	-1.6	-1.3	-1.4	-1.5	-1.4	-0.4	-1.3	-1.5	-1.6	1.7	0.8	0.3	0.1
Neck or shoulder pain in last month	1.9	2.8	6.0	1.8	1.4	2.4	1.7	1.8	1.4	1.6	1.8	1.5	1.6	-2.0	0.4	1.2	1.6
Medication: Blood pressure	4.1	7.2	13.4	2.9	2.5	3.7	2.2	2.8	2.5	2.2	2.6	3.4	3.2	-3.3	1.1	2.4	1.7
Angina (self-reported)	0.6	0.8	2.1	0.4	-1.4	-0.0	-0.0	1.1	1.3	-1.0	-0.6	-0.1	-0.8	0.8	1.4	1.0	-0.3
Migraine (self-reported)	2.6	3.2	6.3	1.7	1.8	2.3	1.6	2.2	1.9	1.4	1.6	2.5	2.4	-1.4	0.8	1.7	0.6
Medication: Ibuprofen	0.8	0.9	3.7	-1.5	0.6	-0.2	-1.1	-0.8	-0.2	-0.3	-1.3	-0.6	-0.2	0.5	1.9	-0.9	-1.2
Medication: Allopurinol	5.4	7.2	14.1	3.8	2.0	2.9	3.3	3.5	3.5	1.8	3.0	3.1	1.9	-2.5	-0.6	2.6	0.9
Medication: Omeprazole	0.3	0.3	2.5	0.2	0.7	0.5	-0.0	-0.2	-0.2	-0.3	0.8	0.4	1.6	-0.2	-0.0	-0.1	0.4
Medication: Seretide 50 evohaler	1.2	1.4	8.1	0.2	-2.9	-0.6	-1.0	-0.5	-1.6	-1.1	-0.3	-0.9	-1.5	1.1	1.1	0.2	0.5
Mean time to correctly identify matches	1.4	2.7	5.4	2.3	1.3	1.8	2.3	2.1	1.9	0.8	2.1	2.2	1.1	-1.1	-0.7	1.0	0.9
Heart disease (mother)	0.3	0.4	1.4	0.8	-0.5	0.5	0.8	0.8	0.4	-0.4	0.4	0.6	0.5	0.6	0.2	1.2	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.2	5.8	1.0	2.4	0.9	1.2	1.3	1.2	-0.4	0.7	1.3	0.7	-0.9	0.3	0.7	-0.0
Whole body fat mass	0.3	1.2	4.8	-0.3	2.0	0.2	0.6	0.8	2.2	-0.5	-1.4	0.6	1.1	0.4	1.6	0.5	-0.2
Leg fat mass (right)	0.2	1.0	3.9	-0.6	1.1	-0.2	0.5	0.6	1.9	-0.7	-2.0	0.1	0.9	0.5	1.5	0.2	-0.1
Arm predicted mass (right)	0.5	2.6	7.3	-0.4	2.6	0.6	0.5	1.0	2.5	0.8	-1.2	1.7	1.6	-1.0	2.7	2.0	1.6
Pulse rate, automated reading	0.1	0.3	1.3	-0.5	-0.7	-0.0	-0.8	-0.6	-0.2	-0.3	0.1	-0.2	0.9	0.2	0.7	1.1	0.5
Alcohol intake frequency.	1.2	2.9	6.6	-2.6	1.3	-1.6	-1.4	-1.7	-0.5	-2.1	-2.3	-0.7	0.6	2.5	0.5	-1.3	-2.2
Comparative height size at age 10	1.0	5.3	12.5	0.5	3.5	2.6	0.2	1.0	1.1	2.9	0.9	2.3	3.2	-3.1	3.1	1.8	2.2
Number of full sisters	0.6	0.8	2.1	0.1	0.8	0.3	1.0	1.4	1.3	0.9	-0.2	0.9	0.8	-0.9	0.3	0.6	1.5
Suffer from ‘nerves’	5.1	8.0	14.1	-3.5	-0.9	-2.8	-3.1	-3.2	-2.8	-2.5	-3.8	-3.5	-2.8	2.4	1.6	-3.1	-1.8
Overall health rating	0.8	1.8	7.2	-0.1	-1.3	-1.7	-0.2	0.6	-0.2	-2.7	-1.6	-0.9	-1.1	2.1	1.0	-0.7	-1.7
Chest pain or discomfort	1.4	2.0	4.4	-1.0	-2.0	-1.3	-0.9	-0.4	-1.4	-1.9	-1.4	-1.3	-2.1	1.9	0.9	-0.6	-1.5
Had major operations	1.6	1.9	4.4	1.3	0.2	1.1	1.6	1.3	1.3	2.1	1.9	1.5	0.9	-1.5	-2.0	0.1	0.4
Age at last live birth	2.5	3.6	8.1	-2.9	-1.8	-1.6	-1.8	-2.0	-1.8	-1.8	-2.5	-2.0	-1.8	2.4	1.0	-0.1	-1.7
Family relationship satisfaction	1.6	1.9	5.4	-1.5	0.0	-1.7	-0.4	-0.3	-0.1	-0.9	-1.6	-0.9	-1.8	2.1	0.6	-2.0	-2.3
Leg pain on walking	0.9	1.1	4.4	-0.7	-0.6	-1.4	-0.5	-0.7	-0.1	-0.5	-1.0	-0.9	-2.1	0.9	-0.7	-1.7	-1.2
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	1.9	-0.8	0.4	-1.0	-0.3	0.1	0.8	-1.4	-1.3	0.1	-0.2	1.1	1.2	-0.1	-0.4
Commuting to job workplace: Car/motor vehicle	1.0	1.2	3.5	0.8	1.3	1.6	0.9	0.7	1.2	0.9	0.6	1.2	1.3	-0.6	0.6	1.9	0.5
Illness, injury, bereavement, stress in last 2 years	1.8	2.2	7.8	1.4	2.8	1.2	1.3	1.1	1.5	0.7	1.9	1.7	1.9	-1.1	-1.7	0.3	-0.5
Medication: Aspirin	0.9	1.2	3.0	1.5	0.9	0.8	1.6	1.7	1.0	0.2	1.1	1.3	0.5	-1.2	-1.4	-0.1	-0.0
Supplements: Vitamin C	0.5	0.6	2.2	-0.4	-0.7	-0.7	-0.7	-0.3	-0.1	-1.5	-1.2	-0.6	-0.8	0.8	0.9	0.8	0.1
Knee pain experienced in last month	2.4	3.8	11.0	2.3	1.6	1.7	2.6	2.5	3.3	0.8	2.3	2.6	1.3	-0.5	-1.2	1.4	0.3
Hypertension (Self-reported)	2.5	6.9	12.1	3.5	2.4	3.4	1.7	1.8	1.9	2.3	2.9	3.1	3.2	-3.0	1.0	2.7	2.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	0.9	-0.9	-0.1	0.2	-0.6	-0.9	-0.3	-0.0	-0.9	-0.2	0.8	0.3	0.7	-0.2	-0.3
Illnesses of father: Heart disease	0.6	0.8	2.6	1.1	0.4	1.4	0.9	0.8	-0.1	-0.3	0.4	0.9	0.9	-0.7	0.5	1.6	1.0
Illnesses of siblings: Diabetes	0.6	0.7	2.1	-0.2	-1.4	-1.2	-0.7	-0.8	-0.9	-1.4	-0.9	-0.3	-0.9	0.5	0.1	-0.0	0.4
Smoking status: Previous	1.1	1.7	3.8	1.1	-0.1	1.5	2.0	1.8	1.5	1.1	0.7	0.8	1.0	-1.6	-1.1	1.0	1.6
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	7.3	-0.6	2.7	0.6	0.0	-0.0	0.6	0.7	0.2	0.8	0.9	-0.7	0.9	0.4	-0.1
Whole body fat-free mass	0.6	3.5	9.6	-0.5	2.9	1.1	0.5	1.2	2.5	1.1	-0.9	2.0	2.2	-1.3	3.1	2.4	1.7
Leg fat-free mass (right)	0.5	2.9	9.8	-0.6	2.8	1.1	0.5	1.2	2.4	0.7	-0.9	1.8	1.9	-0.8	3.1	2.1	1.0
Arm fat percentage (left)	0.1	0.5	1.9	-0.1	1.0	0.2	0.5	0.5	1.4	-0.6	-1.2	0.1	1.0	0.6	0.7	-0.1	0.0
Average weekly red wine intake	0.4	0.6	3.5	0.0	-1.9	0.0	-0.5	-0.3	-0.6	0.5	-0.2	-0.9	-0.7	-0.6	0.2	0.5	1.4
Handedness (chirality/laterality): Left-handed	2.1	2.5	6.3	-2.5	0.2	-1.4	-1.6	-1.5	-0.5	-1.2	-2.1	-0.9	-0.8	2.4	1.8	-1.4	-2.0
Mood swings	1.6	2.8	6.9	-1.3	-1.3	-2.0	-1.1	-1.3	-1.5	-2.1	-1.8	-2.0	-1.6	1.8	0.1	-2.6	-1.7
Loneliness, isolation	2.2	3.1	7.3	-2.0	-1.6	-2.3	-1.3	-1.1	-0.3	-1.9	-2.7	-2.4	-2.5	1.6	1.0	-1.3	-0.3
Long-standing illness, disability or infirmity	1.2	1.8	7.1	-0.6	-0.7	-1.7	-0.5	0.1	-0.9	-2.7	-0.7	-0.7	-1.7	2.0	-0.4	-1.0	-2.0
Ever had bowel cancer screening	0.4	0.4	1.7	-0.4	-0.5	-0.8	-0.1	-0.2	-1.1	-0.4	-0.1	-0.9	0.0	0.5	-0.5	-0.7	-1.3
Diabetes diagnosed by doctor	0.3	0.5	1.9	0.5	-1.2	-0.2	-0.2	0.0	-0.1	-1.4	-0.8	-0.5	-0.8	0.5	0.4	0.9	0.1
Ever had stillbirth, spontaneous miscarriage or termination	1.3	1.4	4.5	-0.7	-2.1	-1.5	-0.4	-0.7	-0.6	-1.7	-1.4	-1.6	-0.3	1.3	-0.1	-1.3	-0.6
Friendships satisfaction	2.2	2.7	9.0	-1.9	-0.7	-1.8	-1.5	-1.2	0.2	-1.6	-2.0	-1.1	-1.7	3.0	1.5	-0.6	-2.0
Qualifications: nursing, teaching	1.7	2.6	7.8	-2.8	-1.0	-1.6	-1.4	-1.7	-1.1	-1.1	-1.7	-1.8	-1.6	2.2	-0.1	-0.8	-1.8
Commuting to job workplace: Walk	0.3	0.3	1.3	-0.0	0.6	0.3	0.3	0.2	0.8	-0.0	0.7	1.0	0.6	0.3	-1.1	-0.3	-0.7
Eye problems/disorders: Cataract	0.4	0.5	2.1	-0.4	-0.3	-0.0	-0.7	-0.3	-0.3	-1.4	-0.7	-0.2	-0.3	0.9	0.8	1.2	-0.3
Mouth/teeth dental problems: Mouth ulcers	1.3	2.0	4.8	-1.3	-1.7	-1.8	-0.5	-0.7	-1.1	-1.0	-1.6	-2.2	-1.8	1.8	-0.5	-1.1	-1.5
Medication for cholesterol	1.4	2.1	7.2	-1.9	-0.7	-1.3	-0.8	-1.1	-1.7	-0.5	-0.6	-1.1	-0.7	1.3	-1.8	-2.0	-2.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.4	0.1	0.4	-0.4	-0.3	0.2	0.3	0.6	0.1	0.2	-0.5	-0.3	0.1	-0.2	-0.1
Back pain experienced in last month	1.8	2.6	7.1	2.1	-0.3	1.7	2.5	1.8	1.0	0.9	0.6	1.0	1.3	-1.7	-1.0	2.7	1.7
Mineral and other dietary supplements	2.7	3.6	6.7	-2.2	0.3	-2.3	-2.6	-2.3	-2.3	-1.8	-1.7	-1.6	-1.7	1.8	0.4	-2.0	-1.9
Breast cancer (self-reported)	0.3	0.3	1.1	-0.3	-0.5	-0.4	-0.1	-0.4	-0.9	-0.1	-0.2	-0.5	-0.8	0.6	-0.7	-0.4	-1.1
Asthma (self-reported)	0.9	1.8	7.6	-1.3	-1.5	-0.8	-2.1	-1.1	-2.8	-0.7	-0.5	-1.6	0.1	1.1	0.9	-1.2	-0.9
Osteoporosis (self-reported)	0.6	0.8	2.0	-0.9	-0.5	-1.0	-0.6	-1.1	-1.0	-1.1	-1.0	-1.1	-0.8	1.4	-0.0	0.0	-0.8
Osteoarthritis (self-reported)	1.7	2.2	5.3	1.5	0.7	1.2	1.8	2.3	2.2	-0.2	1.2	2.3	1.5	-0.2	0.3	1.9	-0.0
Medication: Aspirin	0.9	1.2	2.6	1.5	1.1	1.1	1.4	1.6	1.1	0.1	1.2	1.4	0.6	-1.1	-0.8	0.5	-0.0
Medication: Gliclazide	0.1	0.1	0.5	0.1	-0.7	-0.0	0.3	0.3	-0.1	0.4	-0.7	-0.7	-0.2	-0.3	0.2	-0.1	0.2
Illnesses of father: None of the above (group 1)	0.4	0.5	1.4	0.3	0.7	0.1	0.3	0.8	1.0	1.1	1.2	1.1	1.0	-0.3	-0.3	0.0	-0.4
Smoking status: Current	0.7	1.1	5.4	2.3	0.5	0.7	1.6	1.3	1.2	0.0	1.4	1.2	0.5	-0.5	-0.3	-0.2	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.4	4.7	-0.2	1.6	0.5	1.2	0.7	1.5	2.2	1.1	1.2	0.8	-0.7	-2.0	-0.2	-0.8
Whole body water mass	0.6	3.5	9.0	-0.4	2.9	1.2	0.6	1.3	2.5	1.1	-0.8	2.0	2.3	-1.3	3.0	2.4	1.7
Leg predicted mass (right)	0.5	2.9	9.5	-0.6	2.8	1.1	0.5	1.3	2.5	0.7	-1.0	1.8	1.9	-0.8	3.1	2.1	0.9
Arm fat mass (left)	0.3	1.2	4.5	-0.2	1.7	0.5	0.6	0.8	2.1	-0.2	-1.3	0.7	1.4	0.1	1.8	0.8	0.6
Number of self-reported non-cancer illnesses	0.4	0.7	4.1	0.3	0.6	0.1	-1.0	-0.3	-0.9	-1.4	-0.2	-0.0	0.3	0.8	2.0	0.8	-0.3
Average weekly champagne plus white wine intake	0.9	1.2	3.5	-1.9	-0.4	-0.4	-1.1	-1.6	-1.5	-0.4	-1.0	-1.2	-0.4	1.2	-0.2	-0.7	-1.3
Miserableness	4.6	8.0	14.7	-2.7	-2.7	-3.1	-3.1	-2.8	-2.4	-2.6	-2.8	-3.5	-3.8	2.6	1.1	-3.3	-2.1
Guilty feelings	2.9	4.4	9.7	-2.7	-1.9	-2.5	-1.9	-2.3	-1.4	-1.3	-2.3	-2.5	-2.3	1.8	0.1	-3.1	-1.4
Wears glasses or contact lenses	0.3	0.3	1.9	-0.9	0.1	0.2	0.2	0.1	-0.4	0.8	-0.3	-0.1	-0.2	0.0	-1.4	-0.5	-0.3
Ever taken oral contraceptive pill	0.3	0.3	1.5	-0.8	-0.6	-0.0	-0.5	-0.3	-0.1	-0.6	-0.7	-0.1	-0.2	0.7	1.2	0.6	0.5
Hearing aid user	1.6	1.9	3.7	-1.8	-1.6	-1.4	-1.8	-1.7	-1.4	-0.7	-1.9	-1.6	-1.4	0.9	0.3	-1.1	0.2
Mother’s age at death	2.6	3.2	8.1	-1.9	-2.4	-2.6	-1.0	-1.3	-1.4	-0.8	-1.4	-1.7	-2.8	1.8	-0.9	-2.2	-1.4
Financial situation satisfaction	1.4	1.8	5.1	-1.0	-0.7	-0.9	-0.9	-0.2	0.4	-1.5	-1.7	-0.2	-1.7	1.9	2.3	-1.4	-1.7
Tinnitus: Yes, now most or all of the time	0.6	0.7	2.0	-0.8	0.4	-0.8	-0.7	-1.4	-0.6	-0.8	-1.1	-1.2	-1.1	0.6	-0.4	-0.8	-0.3
Commuting to job workplace: Public transport	0.5	0.6	4.0	-0.7	-2.0	-1.0	-0.5	-0.4	-0.7	-0.5	-0.4	-0.5	-0.4	0.3	-0.2	-0.8	0.2
Eye problems/disorders: Glaucoma	1.2	1.4	5.6	2.4	-0.1	1.1	1.0	1.2	1.2	0.0	1.4	1.3	0.3	-0.2	-0.3	1.9	1.2
Medication: Blood pressure	2.7	5.1	9.7	3.1	1.8	2.7	1.6	1.8	2.3	1.6	2.5	2.5	2.1	-2.0	1.3	2.9	2.5
Pain type(s) experienced in last month: Hip pain	0.7	0.9	3.3	0.5	-0.3	0.7	0.8	0.8	1.1	-0.1	0.1	0.9	0.7	-0.0	1.1	1.7	1.8
Supplements: Fish oil (including cod liver oil)	4.0	5.2	10.2	2.1	1.4	2.6	2.8	2.4	3.2	2.0	1.7	2.5	3.2	-2.0	-0.6	2.1	1.6
High cholesterol (Self-reported)	1.9	3.4	10.2	3.2	0.5	2.2	1.7	1.9	1.9	0.4	2.5	2.3	0.9	-1.0	-0.2	2.7	1.2
Medication: Bendroflumethiazide	1.9	2.8	7.6	1.9	1.0	1.9	0.9	1.0	1.5	1.2	1.4	1.8	1.7	-1.4	1.5	2.5	2.8
Medication: Paracetamol	0.4	0.6	1.9	0.6	0.6	0.9	0.7	0.2	0.2	0.6	0.6	0.4	1.0	-1.4	-1.3	0.2	1.2
Medication: Lisinopril	1.0	1.3	2.6	1.4	-0.8	1.2	1.6	1.5	1.1	1.3	1.3	0.6	0.4	-1.2	-0.8	1.0	1.0
Medication: Atorvastatin	0.1	0.2	0.4	0.6	0.2	0.3	0.6	0.7	0.1	0.2	0.4	0.3	0.1	-0.5	-0.1	-0.5	-0.3
Illnesses of father: High blood pressure	1.0	1.3	3.8	1.6	-0.9	1.3	0.8	0.4	-0.0	1.2	1.1	0.6	1.3	-1.2	-0.1	1.3	2.0
Alcohol drinker status: Never	0.8	1.0	4.1	-0.5	2.0	-0.1	-0.2	-0.6	0.9	-1.1	-0.7	0.3	0.8	1.5	0.1	0.7	-1.8
Ever smoked	0.2	0.3	1.2	0.7	-0.7	0.2	1.1	0.8	0.5	-0.2	-0.5	-0.5	-0.2	-0.1	-0.3	0.1	0.6
Basal metabolic rate	0.6	3.2	9.3	-0.6	2.9	1.0	0.5	1.2	2.5	0.9	-1.1	1.9	2.2	-1.0	3.0	2.1	1.4
Leg fat percentage (left)	0.2	0.7	2.9	-0.3	0.7	-0.4	0.6	0.3	1.7	-0.6	-1.7	-0.0	0.6	0.7	0.7	-0.5	-0.4
Arm fat-free mass (left)	0.6	3.0	8.3	-0.4	2.5	0.9	0.7	1.3	2.5	0.8	-1.1	1.8	2.0	-1.1	2.9	2.3	1.5
Number of operations (self-reported)	0.4	0.6	1.8	0.4	-1.3	-0.4	1.1	0.7	0.6	0.4	0.6	0.1	-0.9	0.3	-1.3	-0.2	-1.2
Average weekly beer plus cider intake	1.3	1.9	5.5	2.4	0.3	0.6	1.4	2.1	1.4	1.0	1.9	1.4	0.9	-1.9	-0.4	0.6	1.2
Irritability	1.4	2.3	4.5	-2.0	-1.1	-1.2	-1.4	-1.8	-1.4	-2.1	-1.9	-2.1	-1.5	1.2	0.4	-1.1	-0.9
Risk taking	0.5	0.7	3.1	-1.1	0.4	-0.1	-0.8	0.1	0.2	-0.9	-1.1	0.2	0.7	0.7	1.7	1.1	-0.4
Ever had prostate specific antigen (PSA) test	0.6	0.7	2.1	0.0	0.7	0.9	1.0	1.0	1.0	1.4	0.8	0.4	0.6	-1.4	-0.7	-0.2	0.1
Fractured/broken bones in last 5 years	0.3	0.4	2.7	0.4	1.6	0.9	1.1	0.2	0.2	-0.2	-0.1	0.7	-0.1	-0.4	-0.1	0.6	0.1
Age started oral contraceptive pill	1.2	1.5	6.7	-0.9	-1.2	-1.3	-1.2	-1.4	-2.6	-0.2	-0.5	-0.6	-1.1	1.4	-1.1	-0.9	-0.8
Diastolic blood pressure, automated reading	1.6	4.9	10.9	3.3	1.5	2.4	2.3	2.3	2.1	1.4	3.0	2.5	2.3	-1.8	0.4	2.4	1.5
Ever depressed for a whole week	2.5	3.1	5.7	-1.8	-1.4	-2.2	-1.7	-1.0	-1.3	-1.6	-1.7	-1.9	-2.0	2.3	0.8	-2.4	-1.9
Unable to work because of sickness or disability	0.9	1.2	3.1	1.4	0.6	1.0	1.2	1.5	1.5	-0.5	0.7	1.5	0.6	-0.3	0.7	1.8	0.5
Commuting to job workplace: Cycle	0.7	0.8	3.1	-1.2	0.0	-0.6	-0.8	-1.3	-1.8	-0.0	-0.5	-0.6	-0.5	0.2	-1.3	-1.1	-0.6
Myopia	0.3	0.4	1.3	-0.1	-0.2	-0.6	-0.3	0.1	-0.9	1.1	0.9	-0.3	0.3	-0.5	-0.4	-1.2	-0.1
Vascular/heart problems diagnosed by doctor	3.6	9.8	18.4	-4.3	-2.5	-4.2	-2.5	-2.9	-2.4	-2.7	-3.8	-3.8	-3.4	3.2	-1.0	-3.1	-2.3
Cholesterol lowering medication	2.9	4.3	11.8	3.1	1.0	2.4	1.6	1.7	2.2	1.1	1.9	2.5	1.7	-1.4	1.2	3.4	2.2
Medication: Omeprazole (e.g. Zanprol)	1.4	1.8	7.0	1.2	1.1	1.5	0.9	0.8	1.0	0.9	1.9	1.5	2.6	-1.2	0.0	1.0	1.1
Pain experienced in last month	1.1	1.8	4.3	-1.4	-0.7	-1.2	-2.1	-1.9	-1.6	-1.3	-0.9	-1.4	-1.5	1.2	1.1	-0.7	-0.8
Supplements: Calcium	0.5	0.5	3.2	0.1	-1.8	-0.3	0.3	-0.1	-0.3	0.1	0.1	-0.7	-1.0	0.2	-1.4	-0.1	-0.2
Basal cell carcinoma (self-reported)	2.5	3.0	5.2	1.6	2.0	2.1	1.9	2.0	2.2	0.9	1.2	2.3	2.3	-1.4	0.0	1.8	0.5
Heart attack/myocardial infarction (self-reported)	2.6	3.3	6.0	1.9	1.3	2.0	2.4	2.5	2.1	1.6	1.7	1.8	1.9	-2.1	-0.9	1.5	0.9
Deep venous thrombosis (DVT) (self-reported)	1.5	2.0	5.0	-1.0	-1.2	-2.2	-1.8	-1.3	-1.4	-0.6	-1.2	-1.7	-1.6	1.0	0.3	-2.2	-0.6
Heart disease (siblings)	0.4	0.5	2.9	0.3	-1.3	0.1	-0.5	0.1	-0.5	-0.4	-0.3	0.0	0.1	0.1	1.7	0.7	0.7
Alcohol drinker status: Previous	0.3	0.3	1.1	-1.0	0.9	-0.1	-0.0	-0.3	0.2	0.6	-0.1	0.8	1.1	0.2	-0.6	-0.4	-0.0
Pack years of smoking	1.4	2.0	5.9	1.8	0.4	1.2	1.9	1.8	2.4	0.2	1.0	1.6	1.2	-0.9	0.2	2.0	0.9
Impedance of whole body	0.4	1.9	4.9	-0.5	-0.4	-0.7	-1.0	-1.2	-1.9	-0.7	0.7	-1.6	-1.9	0.8	-1.8	-2.2	-2.0
Leg fat mass (left)	0.3	1.1	4.1	-0.5	1.3	-0.2	0.5	0.6	2.0	-0.7	-2.0	0.2	0.8	0.6	1.7	0.0	-0.3
Arm predicted mass (left)	0.7	3.7	8.9	-0.1	2.9	1.2	0.9	1.4	2.7	1.1	-0.8	2.2	2.2	-1.4	3.0	2.5	1.8