Best TWAS P=2.4e-26 · Best GWAS P=4.14e-26 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | DOK6 | 0.18 | 0.18 | lasso | 5 | 0.18 | 3.2e-56 | 10.4 | 10.6 | 2.4e-26 | 0.96 | 0.01 | 0.99 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CD226 | 0.04 | 0.04 | enet | 7 | 0.05 | 5.3e-10 | 10.5 | -10.6 | 4.4e-26 | -0.93 | 0.00 | 1.00 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CD226 | 0.09 | 0.03 | blup | 76 | 0.06 | 1.7e-07 | 10.5 | -9.5 | 1.3e-21 | -0.81 | 0.00 | 1.00 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CD226 | 0.03 | 0.01 | enet | 7 | 0.02 | 4.3e-03 | 2.3 | -8.0 | 1.2e-15 | -0.51 | 0.02 | 0.60 | FALSE |