Best TWAS P=1.08e-10 · Best GWAS P=2.24e-10 conditioned to 0.00641
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | CYB5A | 0.19 | 0.14 | lasso | 6 | 0.11 | 1.2e-08 | 4.7 | -5.1 | 2.6e-07 | -0.40 | 0.98 | 0.02 | FALSE |
| 2 | GTEx | Brain Cerebellum | CYB5A | 0.44 | 0.14 | enet | 18 | 0.20 | 1.3e-06 | 4.7 | 5.9 | 4.7e-09 | 0.50 | 0.31 | 0.68 | FALSE |
| 3 | GTEx | Cells Transformed fibroblasts | CYB5A | 0.21 | 0.07 | lasso | 3 | 0.11 | 2.3e-08 | 4.6 | -5.5 | 3.5e-08 | -0.54 | 0.63 | 0.37 | FALSE |
| 4 | The Cancer Genome Atlas | Glioblastoma Multiforme | CYB5A | 0.17 | 0.14 | enet | 15 | 0.13 | 9.2e-05 | 4.5 | -5.2 | 2.0e-07 | -0.48 | 0.04 | 0.76 | FALSE |
| 5 | The Cancer Genome Atlas | Soft Tissue Sarcoma | CYB5A | 0.04 | 0.02 | enet | 4 | 0.03 | 4.5e-03 | 6.3 | -6.2 | 5.2e-10 | -0.59 | 0.02 | 0.85 | FALSE |
| 6 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | CYB5A | 0.11 | 0.04 | blup | 91 | 0.03 | 2.8e-02 | 5.8 | -6.5 | 1.1e-10 | -0.67 | 0.03 | 0.47 | TRUE |