TWAS
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Traits
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Traits
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Blood Platelet Count
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chr20:730,289-2,617,003
Best TWAS P=1.1e-19 · Best GWAS P=6.86e-54 conditioned to 1.17e-32
1M
1.5M
2M
2.5M
0
10
20
30
40
50
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
YFS
Blood
SIRPA
0.07
0.02
enet
34
0.03
3.6e-11
2.87
9.1
1.1e-19
-0.42
0.98
0.01
TRUE
1
GTEx
Brain Cerebellar Hemisphere
NSFL1C
0.39
-0.01
lasso
6
0.00
2.5e-01
-0.16
-6.8
7.4e-12
0.39
0.06
0.24
TRUE